48 items (Tursiops truncatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GPR176	Probable G-protein coupled receptor 176. (515 aa)
	DRD3	D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
	ADCY5	Adenylate cyclase 5. (1263 aa)
	HTR4	5-hydroxytryptamine receptor 4 isoform X4; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	GRM2	Metabotropic glutamate receptor 2. (1080 aa)
	HTR1A	5-hydroxytryptamine receptor 1A. (422 aa)
	GNAI3	G protein subunit alpha i3. (354 aa)
	GRIK3	Glutamate ionotropic receptor kainate type subunit 3. (880 aa)
	EDNRA	Endothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
	GRM8	Metabotropic glutamate receptor 8-like. (907 aa)
	GPR37	Prosaposin receptor GPR37. (614 aa)
	HTR1F	5-hydroxytryptamine receptor 1F. (365 aa)
	GRM5	Metabotropic glutamate receptor 5 isoform X1. (1199 aa)
	PDE2A	Phosphodiesterase. (936 aa)
	FSHR	Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
	HTR1E	5-hydroxytryptamine receptor 1E. (365 aa)
	OPRK1	Kappa-type opioid receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	OPRM1	Mu-type opioid receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (457 aa)
	S1PR1	Sphingosine 1-phosphate receptor 1 isoform X2; Belongs to the G-protein coupled receptor 1 family. (382 aa)
	SSTR2	Somatostatin receptor type 2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
	OPRL1	Nociceptin receptor; Belongs to the G-protein coupled receptor 1 family. (370 aa)
	EDN1	Endothelin-1. (202 aa)
	GRM4	Glutamate metabotropic receptor 4. (912 aa)
	ADRA2A	alpha-2A adrenergic receptor. (448 aa)
	CHRM5	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (533 aa)
	DRD2	D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (445 aa)
	GNAT1	Guanine nucleotide-binding protein G(T) subunit alpha-1. (350 aa)
	GNAI2	G protein subunit alpha i2. (351 aa)
	GABBR1	Gamma-aminobutyric acid type B receptor subunit 1. (928 aa)
	CHRM2	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)
	LPAR1	Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	GRM1	Metabotropic glutamate receptor 1 isoform X1. (1195 aa)
	HTR5A	5-hydroxytryptamine receptor 5A. (357 aa)
	GABBR2	Gamma-aminobutyric acid type B receptor subunit 2. (940 aa)
	HRH3	Histamine receptor H3. (457 aa)
	PSAP	Prosaposin. (547 aa)
	GPR37L1	Prosaposin receptor GPR37L1. (462 aa)
	ADCY6	Adenylate cyclase 6. (1167 aa)
	PTGDR2	Prostaglandin D2 receptor 2; Belongs to the G-protein coupled receptor 1 family. (394 aa)
	GRM6	Glutamate metabotropic receptor 6. (889 aa)
	GRM3	Metabotropic glutamate receptor 3 isoform X1. (876 aa)
	RIC8A	synembryn-A. (536 aa)
	OPRD1	Delta-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (368 aa)
	FLNA	filamin-A-like. (2634 aa)
	AKAP12	A-kinase anchor protein 12. (1686 aa)
	GRM7	Metabotropic glutamate receptor 7. (924 aa)
	P2RY12	P2Y purinoceptor 12. (339 aa)
	HRH4	Histamine H4 receptor. (322 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	ADCY6	ENSTTRP00000000558	ENSTTRP00000010703	Adenylate cyclase 5.	Adenylate cyclase 6.	0.903
ADCY5	ADRA2A	ENSTTRP00000000558	ENSTTRP00000006604	Adenylate cyclase 5.	alpha-2A adrenergic receptor.	0.651
ADCY5	GNAI2	ENSTTRP00000000558	ENSTTRP00000007306	Adenylate cyclase 5.	G protein subunit alpha i2.	0.922
ADCY5	GNAI3	ENSTTRP00000000558	ENSTTRP00000001378	Adenylate cyclase 5.	G protein subunit alpha i3.	0.916
ADCY5	GNAT1	ENSTTRP00000000558	ENSTTRP00000007304	Adenylate cyclase 5.	Guanine nucleotide-binding protein G(T) subunit alpha-1.	0.541
ADCY5	PDE2A	ENSTTRP00000000558	ENSTTRP00000002791	Adenylate cyclase 5.	Phosphodiesterase.	0.888
ADCY6	ADCY5	ENSTTRP00000010703	ENSTTRP00000000558	Adenylate cyclase 6.	Adenylate cyclase 5.	0.903
ADCY6	ADRA2A	ENSTTRP00000010703	ENSTTRP00000006604	Adenylate cyclase 6.	alpha-2A adrenergic receptor.	0.571
ADCY6	GNAI2	ENSTTRP00000010703	ENSTTRP00000007306	Adenylate cyclase 6.	G protein subunit alpha i2.	0.920
ADCY6	GNAI3	ENSTTRP00000010703	ENSTTRP00000001378	Adenylate cyclase 6.	G protein subunit alpha i3.	0.919
ADCY6	GNAT1	ENSTTRP00000010703	ENSTTRP00000007304	Adenylate cyclase 6.	Guanine nucleotide-binding protein G(T) subunit alpha-1.	0.497
ADCY6	PDE2A	ENSTTRP00000010703	ENSTTRP00000002791	Adenylate cyclase 6.	Phosphodiesterase.	0.888
ADRA2A	ADCY5	ENSTTRP00000006604	ENSTTRP00000000558	alpha-2A adrenergic receptor.	Adenylate cyclase 5.	0.651
ADRA2A	ADCY6	ENSTTRP00000006604	ENSTTRP00000010703	alpha-2A adrenergic receptor.	Adenylate cyclase 6.	0.571
ADRA2A	EDN1	ENSTTRP00000006604	ENSTTRP00000005761	alpha-2A adrenergic receptor.	Endothelin-1.	0.465
ADRA2A	GNAI2	ENSTTRP00000006604	ENSTTRP00000007306	alpha-2A adrenergic receptor.	G protein subunit alpha i2.	0.650
ADRA2A	GNAI3	ENSTTRP00000006604	ENSTTRP00000001378	alpha-2A adrenergic receptor.	G protein subunit alpha i3.	0.574
ADRA2A	GRM5	ENSTTRP00000006604	ENSTTRP00000002786	alpha-2A adrenergic receptor.	Metabotropic glutamate receptor 5 isoform X1.	0.401
CHRM2	CHRM5	ENSTTRP00000008202	ENSTTRP00000006844	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.611
CHRM2	EDN1	ENSTTRP00000008202	ENSTTRP00000005761	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Endothelin-1.	0.858