11 items (Tursiops truncatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HRH4	Histamine H4 receptor. (322 aa)
	HRH3	Histamine receptor H3. (457 aa)
	GNAI2	G protein subunit alpha i2. (351 aa)
	CHRM5	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (533 aa)
	OPRM1	Mu-type opioid receptor isoform X2; Belongs to the G-protein coupled receptor 1 family. (457 aa)
	AGRN	Agrin. (2004 aa)
	RGS10	Regulator of G-protein signaling 10. (164 aa)
	GRK2	G protein-coupled receptor kinase 2. (651 aa)
	GNAQ	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
	GNA11	G protein subunit alpha 11. (359 aa)
	CHRM2	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (466 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHRM2	CHRM5	ENSTTRP00000008202	ENSTTRP00000006844	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.611
CHRM2	GNA11	ENSTTRP00000008202	ENSTTRP00000011654	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit alpha 11.	0.904
CHRM2	GNAI2	ENSTTRP00000008202	ENSTTRP00000007306	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit alpha i2.	0.888
CHRM2	GNAQ	ENSTTRP00000008202	ENSTTRP00000008242	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1.	0.904
CHRM2	GRK2	ENSTTRP00000008202	ENSTTRP00000001761	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein-coupled receptor kinase 2.	0.405
CHRM2	HRH3	ENSTTRP00000008202	ENSTTRP00000010495	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Histamine receptor H3.	0.582
CHRM2	HRH4	ENSTTRP00000008202	ENSTTRP00000016201	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Histamine H4 receptor.	0.582
CHRM5	CHRM2	ENSTTRP00000006844	ENSTTRP00000008202	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.611
CHRM5	GNA11	ENSTTRP00000006844	ENSTTRP00000011654	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit alpha 11.	0.958
CHRM5	GNAI2	ENSTTRP00000006844	ENSTTRP00000007306	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit alpha i2.	0.571
CHRM5	GNAQ	ENSTTRP00000006844	ENSTTRP00000008242	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1.	0.939
CHRM5	GRK2	ENSTTRP00000006844	ENSTTRP00000001761	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein-coupled receptor kinase 2.	0.604
CHRM5	HRH3	ENSTTRP00000006844	ENSTTRP00000010495	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Histamine receptor H3.	0.452
CHRM5	HRH4	ENSTTRP00000006844	ENSTTRP00000016201	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Histamine H4 receptor.	0.452
GNA11	CHRM2	ENSTTRP00000011654	ENSTTRP00000008202	G protein subunit alpha 11.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.904
GNA11	CHRM5	ENSTTRP00000011654	ENSTTRP00000006844	G protein subunit alpha 11.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.958
GNA11	GNAQ	ENSTTRP00000011654	ENSTTRP00000008242	G protein subunit alpha 11.	Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1.	0.913
GNA11	GRK2	ENSTTRP00000011654	ENSTTRP00000001761	G protein subunit alpha 11.	G protein-coupled receptor kinase 2.	0.998
GNA11	OPRM1	ENSTTRP00000011654	ENSTTRP00000004570	G protein subunit alpha 11.	Mu-type opioid receptor isoform X2; Belongs to the G-protein coupled receptor 1 family.	0.626
GNA11	RGS10	ENSTTRP00000011654	ENSTTRP00000013819	G protein subunit alpha 11.	Regulator of G-protein signaling 10.	0.440