STRINGSTRING
ARHGAP42 ARHGAP42 STK39 STK39 NAV2 NAV2 GLP1R GLP1R LVRN LVRN NOS3 NOS3 GRIP2 GRIP2 DDAH1 DDAH1 UMOD UMOD EDNRB EDNRB ACE ACE ATP1A2 ATP1A2 AVPR1A AVPR1A EDNRA EDNRA ADH5 ADH5 NPY1R NPY1R ERAP2 ERAP2 LNPEP LNPEP CORIN CORIN EXT2 EXT2 SPX SPX FSHR FSHR CPA3 CPA3 ACE2 ACE2 F2RL1 F2RL1 COL1A2 COL1A2 GNA12 GNA12 ECE1 ECE1 AGT AGT RNLS RNLS ACTA2 ACTA2 AR AR ADRB1 ADRB1 MECP2 MECP2 ADRA1A ADRA1A ACVRL1 ACVRL1 BMPR2 BMPR2 EMILIN1 EMILIN1 NPR3 NPR3 EDN2 EDN2 TBXA2R TBXA2R NCALD NCALD OXTR OXTR EDN1 EDN1 MKKS MKKS SLC4A5 SLC4A5 ATP2B1 ATP2B1 SERPINF2 SERPINF2 PTGS1 PTGS1 ADM ADM F2R F2R DRD2 DRD2 AVPR2 AVPR2 NPY NPY GCH1 GCH1 GSK3A GSK3A ADRB2 ADRB2 UTS2B UTS2B ID2 ID2 REN REN WNK1 WNK1 GAS6 GAS6 F11R F11R GNA13 GNA13 ENSTTRP00000008884 ENSTTRP00000008884 EDN3 EDN3 OR51E2 OR51E2 AGTR1 AGTR1 KCNK6 KCNK6 ADRA1D ADRA1D PRCP PRCP PLCB3 PLCB3 UTS2 UTS2 ENSTTRP00000010071 ENSTTRP00000010071 EMP2 EMP2 CORO2A CORO2A ENSTTRP00000010502 ENSTTRP00000010502 ASIC2 ASIC2 GPR37L1 GPR37L1 CARTPT CARTPT NPPA NPPA ATP1A1 ATP1A1 RAMP2 RAMP2 BBS4 BBS4 SCPEP1 SCPEP1 OXT OXT NDST2 NDST2 PTGS2 PTGS2 GNA11 GNA11 UCN UCN ADRA1B ADRA1B TAC3 TAC3 KCNQ1 KCNQ1 NOX1 NOX1 DLL1 DLL1 RASL10B RASL10B P2RX4 P2RX4 EXT1 EXT1 NPR1 NPR1 QRFP QRFP PTPRO PTPRO ENPEP ENPEP ANPEP ANPEP AVPR1B AVPR1B TNNI3 TNNI3 TRHDE TRHDE CORO2B CORO2B ERAP1 ERAP1 LRP5 LRP5 ADIPOQ ADIPOQ ABCC9 ABCC9 RHOA RHOA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ARHGAP42Rho GTPase-activating protein 42. (653 aa)
STK39STE20/SPS1-related proline-alanine-rich protein kinase isoform X1. (538 aa)
NAV2Neuron navigator 2 isoform X1. (2479 aa)
GLP1RGlucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. (441 aa)
LVRNAminopeptidase. (867 aa)
NOS3Nitric oxide synthase 3. (1197 aa)
GRIP2Glutamate receptor-interacting protein 2-like. (1028 aa)
DDAH1N(G),N(G)-dimethylarginine dimethylaminohydrolase 1. (285 aa)
UMODUromodulin. (657 aa)
EDNRBEndothelin B receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (530 aa)
ACEAngiotensin-converting enzyme. (1308 aa)
ATP1A2ATPase Na+/K+ transporting subunit alpha 2. (1020 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa)
NPY1RNeuropeptide Y receptor type 1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
ERAP2Aminopeptidase. (926 aa)
LNPEPLeucyl-cystinyl aminopeptidase. (1052 aa)
CORINAtrial natriuretic peptide-converting enzyme. (981 aa)
EXT2Exostosin-2 isoform X3; Belongs to the glycosyltransferase 47 family. (726 aa)
SPXSpexin. (115 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
CPA3LOW QUALITY PROTEIN: mast cell carboxypeptidase A. (413 aa)
ACE2Angiotensin-converting enzyme. (804 aa)
F2RL1Proteinase-activated receptor 2. (397 aa)
COL1A2Collagen alpha-2(I) chain isoform X1. (1360 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (382 aa)
ECE1Endothelin-converting enzyme 1-like. (771 aa)
AGTAngiotensinogen; Belongs to the serpin family. (484 aa)
RNLSRenalase isoform X1. (342 aa)
ACTA2Actin, aortic smooth muscle. (378 aa)
ARAndrogen receptor. (886 aa)
ADRB1Beta-1 adrenergic receptor. (467 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
ADRA1Aalpha-1A adrenergic receptor. (423 aa)
ACVRL1Activin A receptor like type 1. (497 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
EMILIN1EMILIN-1. (994 aa)
NPR3Atrial natriuretic peptide receptor 3 isoform X2. (532 aa)
EDN2Endothelin-2. (180 aa)
TBXA2RThromboxane A2 receptor. (324 aa)
NCALDNeurocalcin delta. (172 aa)
OXTROxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (391 aa)
EDN1Endothelin-1. (202 aa)
MKKSMcKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin. (568 aa)
SLC4A5Anion exchange protein. (1118 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1217 aa)
SERPINF2Alpha-2-antiplasmin; Belongs to the serpin family. (494 aa)
PTGS1Prostaglandin G/H synthase 1. (600 aa)
ADMADM. (185 aa)
F2RProteinase-activated receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (426 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (445 aa)
AVPR2Arginine vasopressin receptor 2. (370 aa)
NPYPro-neuropeptide Y isoform X2. (97 aa)
GCH1GTP cyclohydrolase 1 isoform X1. (249 aa)
GSK3AGlycogen synthase kinase-3 alpha. (483 aa)
ADRB2Beta-2 adrenergic receptor. (418 aa)
UTS2Burotensin-2B. (118 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
RENRenin isoform X1; Belongs to the peptidase A1 family. (407 aa)
WNK1Serine/threonine-protein kinase WNK1 isoform X2. (2240 aa)
GAS6Growth arrest specific 6. (719 aa)
F11RJunctional adhesion molecule A isoform X1. (298 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (282 aa)
ENSTTRP00000008884annotation not available (287 aa)
EDN3Endothelin-3. (213 aa)
OR51E2Olfactory receptor. (324 aa)
AGTR1Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
KCNK6Potassium channel subfamily K member 6; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (313 aa)
ADRA1Dalpha-1D adrenergic receptor. (569 aa)
PRCPLysosomal Pro-X carboxypeptidase. (514 aa)
PLCB3Phosphoinositide phospholipase C. (1230 aa)
UTS2Urotensin-2. (137 aa)
ENSTTRP00000010071annotation not available (254 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
CORO2ACoronin 2A. (525 aa)
ENSTTRP00000010502annotation not available (261 aa)
ASIC2Acid-sensing ion channel 2; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (361 aa)
GPR37L1Prosaposin receptor GPR37L1. (462 aa)
CARTPTCocaine- and amphetamine-regulated transcript protein. (81 aa)
NPPAAtrial natriuretic peptide. (177 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
RAMP2Receptor activity modifying protein 2. (176 aa)
BBS4Bardet-Biedl syndrome 4 protein. (516 aa)
SCPEP1Carboxypeptidase; Belongs to the peptidase S10 family. (426 aa)
OXTOxytocin-neurophysin 1; Belongs to the vasopressin/oxytocin family. (85 aa)
NDST2Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2. (883 aa)
PTGS2Prostaglandin G/H synthase 2. (603 aa)
GNA11G protein subunit alpha 11. (359 aa)
UCNUrocortin. (126 aa)
ADRA1Balpha-1B adrenergic receptor. (395 aa)
TAC3Tachykinin precursor 3. (139 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1. (673 aa)
NOX1LOW QUALITY PROTEIN: NADPH oxidase 1. (558 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (784 aa)
RASL10BRas-like protein family member 10B isoform X2. (131 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (388 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
NPR1Natriuretic peptide receptor 1. (1055 aa)
QRFPPyroglutamylated RFamide peptide. (134 aa)
PTPROReceptor-type tyrosine-protein phosphatase O isoform X1. (1181 aa)
ENPEPAminopeptidase. (693 aa)
ANPEPAminopeptidase N. (964 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (355 aa)
TNNI3Troponin I3, cardiac type. (211 aa)
TRHDEThyrotropin-releasing hormone-degrading ectoenzyme. (996 aa)
CORO2BCoronin; Belongs to the WD repeat coronin family. (431 aa)
ERAP1Aminopeptidase. (946 aa)
LRP5LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5. (1582 aa)
ADIPOQAdiponectin. (242 aa)
ABCC9ATP-binding cassette sub-family C member 9. (1540 aa)
RHOATransforming protein RhoA. (193 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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