STRINGSTRING
DGKQ DGKQ BMP2 BMP2 REST REST DKKL1 DKKL1 EGR1 EGR1 BMP5 BMP5 SIRT5 SIRT5 DKK3 DKK3 LOC101333926 LOC101333926 H6PD H6PD CLCN2 CLCN2 ENSTTRP00000012446 ENSTTRP00000012446 PPTC7 PPTC7 BMP6 BMP6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DGKQDiacylglycerol kinase. (949 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
RESTRE1-silencing transcription factor. (656 aa)
DKKL1Dickkopf-like protein 1 isoform X1. (209 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (509 aa)
BMP5Bone morphogenetic protein 5 isoform X2. (454 aa)
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinyl [...] (309 aa)
DKK3Dickkopf-related protein 3. (282 aa)
LOC101333926RE1-silencing transcription factor-like. (974 aa)
H6PDGDH/6PGL endoplasmic bifunctional protein. (791 aa)
CLCN2Chloride voltage-gated channel 2. (901 aa)
ENSTTRP00000012446annotation not available (184 aa)
PPTC7Protein phosphatase; Belongs to the PP2C family. (304 aa)
BMP6Bone morphogenetic protein 6. (304 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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