STRINGSTRING
IRF6 IRF6 LRG1 LRG1 FGFR2 FGFR2 ZFP36L1 ZFP36L1 ZFP36 ZFP36 IFT52 IFT52 IFT74 IFT74 PTPRK PTPRK CASK CASK MED1 MED1 TGM1 TGM1 FGF7 FGF7 FGF10 FGF10 PTCH1 PTCH1 TP63 TP63 YAP1 YAP1 ZEB1 ZEB1 STXBP4 STXBP4 BCL11B BCL11B VDR VDR INTU INTU ENSTTRP00000013191 ENSTTRP00000013191 PRKD1 PRKD1 CD109 CD109 SRSF6 SRSF6 CDH3 CDH3 IFT57 IFT57 SFN SFN KDF1 KDF1 OVOL1 OVOL1 KLF9 KLF9 NOTCH2 NOTCH2 IFT80 IFT80
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IRF6Interferon regulatory factor 6 isoform X2. (467 aa)
LRG1Leucine-rich alpha-2-glycoprotein. (347 aa)
FGFR2Fibroblast growth factor receptor. (811 aa)
ZFP36L1mRNA decay activator protein ZFP36L1. (338 aa)
ZFP36ZFP36 ring finger protein. (322 aa)
IFT52Intraflagellar transport protein 52 homolog isoform X1. (437 aa)
IFT74Intraflagellar transport protein 74 homolog isoform X1. (598 aa)
PTPRKReceptor-type tyrosine-protein phosphatase kappa. (1338 aa)
CASKPeripheral plasma membrane protein CASK isoform X8; Belongs to the MAGUK family. (926 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1512 aa)
TGM1Protein-glutamine gamma-glutamyltransferase K. (824 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF10Fibroblast growth factor 10. (142 aa)
PTCH1Protein patched homolog 1 isoform X1. (1313 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
YAP1Transcriptional coactivator YAP1 isoform X4. (488 aa)
ZEB1Zinc finger E-box-binding homeobox 1 isoform X1. (1120 aa)
STXBP4Syntaxin-binding protein 4. (553 aa)
BCL11BB-cell lymphoma/leukemia 11B. (897 aa)
VDRVitamin D3 receptor. (427 aa)
INTUProtein inturned. (931 aa)
ENSTTRP00000013191annotation not available (60 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (876 aa)
CD109CD109 antigen isoform X1. (1440 aa)
SRSF6LOW QUALITY PROTEIN: serine/arginine-rich splicing factor 6-like. (259 aa)
CDH3Cadherin-3; Cadherins are calcium-dependent cell adhesion proteins. (830 aa)
IFT57Intraflagellar transport protein 57 homolog. (427 aa)
SFNStratifin. (248 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
OVOL1Ovo like transcriptional repressor 1. (267 aa)
KLF9Krueppel-like factor 9. (212 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa)
IFT80Intraflagellar transport protein 80 homolog isoform X2. (777 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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