STRINGSTRING
LRRC1 LRRC1 LMO4 LMO4 SFRP1 SFRP1 BCL10 BCL10 PRICKLE1 PRICKLE1 PHACTR4 PHACTR4 CECR2 CECR2 RARG RARG MTHFD1 MTHFD1 OPA1 OPA1 DVL3 DVL3 NODAL NODAL HECTD1 HECTD1 CELSR1 CELSR1 BRD2 BRD2 SFRP2 SFRP2 APAF1 APAF1 WNT5A WNT5A TEAD2 TEAD2 MED12 MED12 TULP3 TULP3 FUZ FUZ GRHL2 GRHL2 FZD3 FZD3 MTHFD1L MTHFD1L LRP2 LRP2 KAT2A KAT2A KDM6A KDM6A MKS1 MKS1 PTK7 PTK7 SALL4 SALL4 SEMA4C SEMA4C VASP VASP SUFU SUFU TRAF6 TRAF6 BMP4 BMP4 SPINT2 SPINT2 DVL2 DVL2 ST14 ST14 RALA RALA FOLR1 FOLR1 PTCH1 PTCH1 LHX2 LHX2 PRKACB PRKACB ARHGAP35 ARHGAP35 SPINT1 SPINT1 MTHFR MTHFR BBS4 BBS4 PLXNB2 PLXNB2 HIF1A HIF1A TGFB1 TGFB1 CC2D2A CC2D2A COBL COBL CITED2 CITED2 LIAS LIAS KDM2B KDM2B TSC1 TSC1 GLMN GLMN PRKACA PRKACA SHROOM3 SHROOM3 ABL1 ABL1 BMP7 BMP7 FZD6 FZD6 CTHRC1 CTHRC1 SETD2 SETD2 GRHL3 GRHL3 SEC24B SEC24B IFT57 IFT57 TBXT TBXT TRIM71 TRIM71 RARA RARA CLUAP1 CLUAP1 DVL1 DVL1 SCRIB SCRIB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC1Leucine-rich repeat-containing protein 1 isoform X1. (522 aa)
LMO4LIM domain transcription factor LMO4. (165 aa)
SFRP1Secreted frizzled-related protein 1 isoform X2. (307 aa)
BCL10B-cell lymphoma/leukemia 10. (233 aa)
PRICKLE1Prickle-like protein 1. (832 aa)
PHACTR4Phosphatase and actin regulator. (718 aa)
CECR2Cat eye syndrome critical region protein 2 isoform X2. (1388 aa)
RARGRetinoic acid receptor beta. (453 aa)
MTHFD1C-1-tetrahydrofolate synthase, cytoplasmic isoform X2. (936 aa)
OPA1Dynamin-like 120 kDa protein, mitochondrial isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3. (498 aa)
NODALNodal homolog. (348 aa)
HECTD1E3 ubiquitin-protein ligase HECTD1 isoform X1. (2600 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (3004 aa)
BRD2Bromodomain-containing protein 2 isoform X1. (803 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
APAF1Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1246 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
TEAD2Transcriptional enhancer factor TEF-4 isoform X2. (447 aa)
MED12Mediator of RNA polymerase II transcription subunit 12. (2173 aa)
TULP3Tubby-related protein 3 isoform X1; Belongs to the TUB family. (429 aa)
FUZFuzzy planar cell polarity protein. (419 aa)
GRHL2Grainyhead-like protein 2 homolog isoform X4. (619 aa)
FZD3Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
MTHFD1LMonofunctional C1-tetrahydrofolate synthase, mitochondrial. (901 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4599 aa)
KAT2AHistone acetyltransferase KAT2A. (835 aa)
KDM6ALysine-specific demethylase 6A isoform X4. (1346 aa)
MKS1Meckel syndrome type 1 protein. (559 aa)
PTK7Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
SALL4Sal-like protein 4. (1005 aa)
SEMA4Csemaphorin-4C. (833 aa)
VASPVasodilator-stimulated phosphoprotein. (406 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (423 aa)
TRAF6TNF receptor associated factor 6. (523 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
SPINT2LOW QUALITY PROTEIN: kunitz-type protease inhibitor 2-like. (249 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X9. (736 aa)
ST14Suppression of tumorigenicity 14. (627 aa)
RALARas-related protein Ral-A isoform X1. (206 aa)
FOLR1Folate receptor gamma. (251 aa)
PTCH1Protein patched homolog 1 isoform X1. (1313 aa)
LHX2LIM/homeobox protein Lhx2. (397 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
ARHGAP35Rho GTPase-activating protein 35 isoform X1. (1510 aa)
SPINT1Kunitz-type protease inhibitor 1. (500 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (696 aa)
BBS4Bardet-Biedl syndrome 4 protein. (516 aa)
PLXNB2Plexin B2. (1819 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (824 aa)
TGFB1Transforming growth factor beta 1. (338 aa)
CC2D2ACoiled-coil and C2 domain-containing protein 2A isoform X1. (1519 aa)
COBLProtein cordon-bleu isoform X4. (1337 aa)
CITED2Cbp/p300-interacting transactivator 2. (272 aa)
LIASLipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa)
KDM2BLOW QUALITY PROTEIN: lysine-specific demethylase 2B. (1332 aa)
TSC1Hamartin isoform X1. (1168 aa)
GLMNGlomulin. (589 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (351 aa)
SHROOM3Protein Shroom3 isoform X2. (1948 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (707 aa)
CTHRC1Collagen triple helix repeat-containing protein 1. (197 aa)
SETD2Histone-lysine N-methyltransferase SETD2. (2054 aa)
GRHL3Grainyhead-like protein 3 homolog. (605 aa)
SEC24BProtein transport protein Sec24B. (1253 aa)
IFT57Intraflagellar transport protein 57 homolog. (427 aa)
TBXTBrachyury protein isoform X1. (435 aa)
TRIM71E3 ubiquitin-protein ligase TRIM71. (613 aa)
RARARetinoic acid receptor alpha-like. (618 aa)
CLUAP1Clusterin-associated protein 1 isoform X4. (412 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
SCRIBProtein scribble homolog. (1596 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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