STRINGSTRING
DIPK2A DIPK2A ADPRHL1 ADPRHL1 ARID2 ARID2 ADRA1A ADRA1A POU4F1 POU4F1 S1PR1 S1PR1 SGCD SGCD TENM4 TENM4 WNT5A WNT5A HNRNPU HNRNPU GJC1 GJC1 PRMT1 PRMT1 CBY1 CBY1 CSRP3 CSRP3 TBX18 TBX18 MYL10 MYL10 ZMPSTE24 ZMPSTE24 CAV3 CAV3 MYL7 MYL7 VWA5B1 VWA5B1 LRP2 LRP2 ENSTTRP00000006381 ENSTTRP00000006381 IFRD2 IFRD2 SRF SRF FHOD3 FHOD3 FHL2 FHL2 NOTCH1 NOTCH1 ALPK2 ALPK2 MYLK2 MYLK2 SMAD1 SMAD1 BMPR1A BMPR1A TCAP TCAP PPP1R13L PPP1R13L MED1 MED1 TNNC1 TNNC1 RYR2 RYR2 SEMA3C SEMA3C ASB2 ASB2 BMP4 BMP4 NEBL NEBL C10orf113 C10orf113 PGM5 PGM5 SAV1 SAV1 ENSTTRP00000009296 ENSTTRP00000009296 ITGB1 ITGB1 IFT20 IFT20 KDM6B KDM6B WNT2 WNT2 PLEC PLEC ISL1 ISL1 RARB RARB CXADR CXADR GATA5 GATA5 NEB NEB LRRC10B LRRC10B ENSTTRP00000010661 ENSTTRP00000010661 VWA5B2 VWA5B2 DLL4 DLL4 SGCG SGCG SMAD4 SMAD4 PTCD2 PTCD2 NRAP NRAP NPRL3 NPRL3 MAPK11 MAPK11 NKX2-6 NKX2-6 SLC9A1 SLC9A1 PDGFRA PDGFRA EYA1 EYA1 ACTN2 ACTN2 PRKAR1A PRKAR1A NOX4 NOX4 ATG5 ATG5 TGFB1 TGFB1 MYLK3 MYLK3 GATA6 GATA6 SGCZ SGCZ BMP10 BMP10 TGFB2 TGFB2 TGFBR1 TGFBR1 SHH SHH PLN PLN JARID2 JARID2 ACADM ACADM MYBPC3 MYBPC3 ADPRH ADPRH TSC1 TSC1 ZFPM1 ZFPM1 ANKRD1 ANKRD1 MYL2 MYL2 BVES BVES ALPK3 ALPK3 ENSTTRP00000014726 ENSTTRP00000014726 BMP7 BMP7 MYL3 MYL3 MEF2A MEF2A HEY2 HEY2 ENG ENG EGLN1 EGLN1 DSP DSP RARA RARA TBX20 TBX20 MAML1 MAML1 MYO18B MYO18B FGF9 FGF9 DSG2 DSG2 TBX5 TBX5 MTOR MTOR LMNA LMNA TNNT2 TNNT2 SHOX2 SHOX2 FOXH1 FOXH1 SIK1 SIK1 ALDH1A2 ALDH1A2 NDUFV2 NDUFV2 EDNRA EDNRA BMP2 BMP2 HAND1 HAND1 MYOCD MYOCD TBX3 TBX3 PROX1 PROX1 ZIC3 ZIC3 EYA2 EYA2 XIRP2 XIRP2 MEF2C MEF2C PKP2 PKP2 ZFPM2 ZFPM2 HEG1 HEG1 CHD7 CHD7 SMAD7 SMAD7 NKX2-5 NKX2-5 TBX2 TBX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DIPK2ADeleted in autism protein 1. (430 aa)
ADPRHL1Protein ADP-ribosylarginine hydrolase-like protein 1. (353 aa)
ARID2AT-rich interactive domain-containing protein 2 isoform X2. (1772 aa)
ADRA1Aalpha-1A adrenergic receptor. (423 aa)
POU4F1POU domain protein. (419 aa)
S1PR1Sphingosine 1-phosphate receptor 1 isoform X2; Belongs to the G-protein coupled receptor 1 family. (382 aa)
SGCDDelta-sarcoglycan. (289 aa)
TENM4Teneurin-4. (2766 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform X1. (818 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (387 aa)
PRMT1Protein arginine methyltransferase 1. (360 aa)
CBY1Protein chibby homolog 1 isoform X3. (127 aa)
CSRP3Cysteine and glycine-rich protein 3. (192 aa)
TBX18T-box transcription factor TBX18. (612 aa)
MYL10Myosin light chain 10. (117 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (192 aa)
MYL7Myosin light chain 7. (141 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1212 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4599 aa)
ENSTTRP00000006381annotation not available (382 aa)
IFRD2Interferon-related developmental regulator 2 isoform X2. (584 aa)
SRFSerum response factor isoform X2. (509 aa)
FHOD3LOW QUALITY PROTEIN: FH1/FH2 domain-containing protein 3. (1437 aa)
FHL2Four and a half LIM domains protein 2 isoform X1. (362 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2527 aa)
ALPK2Alpha-protein kinase 2. (2163 aa)
MYLK2Myosin light chain kinase 2. (597 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
TCAPTitin-cap. (167 aa)
PPP1R13LLOW QUALITY PROTEIN: relA-associated inhibitor. (814 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1512 aa)
TNNC1Troponin C, slow skeletal and cardiac muscles. (161 aa)
RYR2Ryanodine receptor 2. (4945 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
ASB2Ankyrin repeat and SOCS box protein 2 isoform X1. (585 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
NEBLNebulette isoform X2. (1011 aa)
C10orf113Uncharacterized protein. (141 aa)
PGM5Phosphoglucomutase-like protein 5; Belongs to the phosphohexose mutase family. (480 aa)
SAV1Protein salvador homolog 1. (385 aa)
ENSTTRP00000009296annotation not available (181 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (786 aa)
IFT20LOW QUALITY PROTEIN: intraflagellar transport protein 20 homolog. (158 aa)
KDM6BDynein heavy chain 2, axonemal. (1642 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
PLECPlectin. (4664 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
RARBRetinoic acid receptor beta. (522 aa)
CXADRCoxsackievirus and adenovirus receptor isoform X1. (365 aa)
GATA5GATA binding protein 5. (398 aa)
NEBNebulin. (6623 aa)
LRRC10BLeucine-rich repeat-containing protein 10B. (242 aa)
ENSTTRP00000010661annotation not available (123 aa)
VWA5B2Von Willebrand factor A domain-containing protein 5B2 isoform X2. (1007 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (750 aa)
SGCGGamma-sarcoglycan. (291 aa)
SMAD4Mothers against decapentaplegic homolog. (407 aa)
PTCD2Pentatricopeptide repeat-containing protein 2, mitochondrial. (388 aa)
NRAPNebulin-related-anchoring protein. (1729 aa)
NPRL3Nitrogen permease regulator 3-like protein isoform X1. (569 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
NKX2-6Homeobox protein Nkx-2.6. (299 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1040 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (589 aa)
ACTN2Alpha-actinin-2 isoform X2. (891 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (380 aa)
NOX4NADPH oxidase 4. (577 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
TGFB1Transforming growth factor beta 1. (338 aa)
MYLK3Myosin light chain kinase 3. (800 aa)
GATA6Transcription factor GATA-6. (592 aa)
SGCZZeta-sarcoglycan isoform X1. (312 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (458 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
JARID2Protein Jumonji. (1235 aa)
ACADMMedium-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1. (454 aa)
MYBPC3Myosin binding protein C, cardiac. (1266 aa)
ADPRHADP-ribosylarginine hydrolase isoform X2. (339 aa)
TSC1Hamartin isoform X1. (1168 aa)
ZFPM1Zinc finger protein ZFPM1. (984 aa)
ANKRD1Ankyrin repeat domain-containing protein 1. (318 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
BVESBlood vessel epicardial substance. (360 aa)
ALPK3Alpha-protein kinase 3 isoform X1. (1851 aa)
ENSTTRP00000014726annotation not available (263 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
MYL3Myosin light chain 3. (197 aa)
MEF2AMyocyte-specific enhancer factor 2A isoform X2. (498 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (336 aa)
ENGEndoglin. (655 aa)
EGLN1Egl nine homolog 1 isoform X1. (378 aa)
DSPDesmoplakin isoform X1. (2806 aa)
RARARetinoic acid receptor alpha-like. (618 aa)
TBX20T-box transcription factor TBX20. (449 aa)
MAML1Mastermind-like protein 1. (1013 aa)
MYO18BLOW QUALITY PROTEIN: unconventional myosin-XVIIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2527 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
DSG2Desmoglein-2 isoform X1. (1116 aa)
TBX5T-box transcription factor TBX5. (519 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2442 aa)
LMNALamin A/C. (664 aa)
TNNT2Troponin T, cardiac muscle. (283 aa)
SHOX2LOW QUALITY PROTEIN: short stature homeobox protein 2. (282 aa)
FOXH1Forkhead box H1. (360 aa)
SIK1Serine/threonine-protein kinase SIK1 isoform X1. (718 aa)
ALDH1A2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa)
NDUFV2NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial. (178 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
MYOCDMyocardin isoform X1. (968 aa)
TBX3T-box transcription factor TBX3. (742 aa)
PROX1Prospero homeobox protein 1. (744 aa)
ZIC3Zinc finger protein ZIC 3 isoform X1. (462 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (542 aa)
XIRP2Xin actin-binding repeat-containing protein 2 isoform X1. (3547 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (472 aa)
PKP2Plakophilin-2. (839 aa)
ZFPM2Zinc finger protein ZFPM2. (1148 aa)
HEG1Protein HEG homolog 1 isoform X1. (1370 aa)
CHD7chromodomain-helicase-DNA-binding protein 7 isoform X3. (2970 aa)
SMAD7Mothers against decapentaplegic homolog 7 isoform X1. (426 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
TBX2T-box transcription factor TBX2. (703 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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