STRINGSTRING
EXOSC2 EXOSC2 TNRC6A TNRC6A DDX3X DDX3X SESN2 SESN2 YTHDF1 YTHDF1 ENSTTRP00000001654 ENSTTRP00000001654 DCP2 DCP2 EXOSC9 EXOSC9 DCPS DCPS PUS7 PUS7 YBX1 YBX1 TARDBP TARDBP TIA1 TIA1 BTG2 BTG2 IREB2 IREB2 FMR1 FMR1 EIF4A3 EIF4A3 RBM24 RBM24 PNPT1 PNPT1 GIGYF2 GIGYF2 CIRBP CIRBP RBM4 RBM4 EIF4G1 EIF4G1 PURA PURA TNRC6B TNRC6B UPF1 UPF1 EXOSC3 EXOSC3 PCIF1 PCIF1 TPR TPR PAIP2B PAIP2B CPEB3 CPEB3 CNOT7 CNOT7 FTO FTO EXOSC5 EXOSC5 DAPK1 DAPK1 LSM14A LSM14A CPEB1 CPEB1 EPRS1 EPRS1 SHMT2 SHMT2 NOCT NOCT YTHDF2 YTHDF2 NANOS2 NANOS2 TSC1 TSC1 YTHDF3 YTHDF3 FXR1 FXR1 PDE12 PDE12 BANK1 BANK1 AGO4 AGO4 AGO1 AGO1 AGO3 AGO3 METTL14 METTL14 TOB1 TOB1 ROCK1 ROCK1 EIF2S1 EIF2S1 UNK UNK LARP1 LARP1 CNOT8 CNOT8 RIDA RIDA GAPDH GAPDH CNOT11 CNOT11 ILF3 ILF3 CNOT10 CNOT10 TRIM71 TRIM71 DHX36 DHX36 RC3H2 RC3H2 GZMB GZMB EIF6 EIF6 TNRC6C TNRC6C CNOT9 CNOT9 PNLDC1 PNLDC1 DND1 DND1 EIF4ENIF1 EIF4ENIF1 MARF1 MARF1 FXR2 FXR2 SRP9 SRP9 MOV10 MOV10 PATL1 PATL1 CNOT6 CNOT6 DIS3L2 DIS3L2 ENSTTRP00000008635 ENSTTRP00000008635 IGFBP5 IGFBP5 MALSU1 MALSU1 ZC3H12A ZC3H12A RC3H1 RC3H1 CAPRIN2 CAPRIN2 CNOT1 CNOT1 NANOS3 NANOS3 SAMD4A SAMD4A GRB7 GRB7 SHMT1 SHMT1 MEX3D MEX3D DCP1A DCP1A EXOSC8 EXOSC8 CAPRIN1 CAPRIN1 PUM1 PUM1 IGF2BP1 IGF2BP1 EXOSC7 EXOSC7 PAN2 PAN2 EIF2AK2 EIF2AK2 CNOT3 CNOT3 ZFP36L2 ZFP36L2 RNF139 RNF139 MRPL13 MRPL13 RPS3 RPS3 ENSTTRP00000005476 ENSTTRP00000005476 CNOT6L CNOT6L RPL13A RPL13A CPEB4 CPEB4 CNOT2 CNOT2 PABPN1L PABPN1L SHFL SHFL LSM1 LSM1 EIF4EBP1 EIF4EBP1 SYNCRIP SYNCRIP DDX6 DDX6 EIF4E EIF4E CPEB2 CPEB2 CALR CALR ZFP36 ZFP36 SAMD4B SAMD4B ZFP36L1 ZFP36L1 PLEKHN1 PLEKHN1 EIF4EBP2 EIF4EBP2 ENSTTRP00000002832 ENSTTRP00000002832 AGO2 AGO2 PARN PARN PAN3 PAN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EXOSC2Exosome complex component RRP4. (289 aa)
TNRC6ATrinucleotide repeat-containing gene 6A protein isoform X9. (1955 aa)
DDX3XATP-dependent RNA helicase DDX3X; Belongs to the DEAD box helicase family. (645 aa)
SESN2Sestrin 2. (470 aa)
YTHDF1YTH domain-containing family protein 1 isoform X2. (554 aa)
ENSTTRP00000001654annotation not available (218 aa)
DCP2m7GpppN-mRNA hydrolase isoform X1. (417 aa)
EXOSC9Exosome complex component RRP45. (456 aa)
DCPSDecapping enzyme, scavenger. (337 aa)
PUS7Pseudouridylate synthase 7 homolog isoform X1. (657 aa)
YBX1Nuclease-sensitive element-binding protein 1 isoform X1. (316 aa)
TARDBPTAR DNA-binding protein 43. (411 aa)
TIA1Nucleolysin TIA-1 isoform X1. (386 aa)
BTG2Protein BTG2 isoform X1. (117 aa)
IREB2Iron-responsive element-binding protein 2 isoform X1; Belongs to the aconitase/IPM isomerase family. (962 aa)
FMR1Synaptic functional regulator FMR1 isoform X1. (597 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (354 aa)
RBM24RNA-binding protein 24. (237 aa)
PNPT1Polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1. (729 aa)
GIGYF2PERQ amino acid-rich with GYF domain-containing protein 2 isoform X1. (1290 aa)
CIRBPCold-inducible RNA-binding protein. (172 aa)
RBM4RNA-binding protein 4 isoform X1. (363 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1537 aa)
PURATranscriptional activator protein Pur-alpha. (325 aa)
TNRC6BTrinucleotide repeat-containing gene 6B protein isoform X8. (1756 aa)
UPF1Regulator of nonsense transcripts 1 isoform X2. (1112 aa)
EXOSC3Exosome complex component RRP40 isoform X1. (275 aa)
PCIF1Phosphorylated CTD-interacting factor 1 isoform X1. (704 aa)
TPRNucleoprotein TPR isoform X3. (2361 aa)
PAIP2BPolyadenylate-binding protein-interacting protein 2B. (121 aa)
CPEB3Cytoplasmic polyadenylation element-binding protein 3 isoform X1. (690 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
FTOAlpha-ketoglutarate-dependent dioxygenase FTO isoform X1. (505 aa)
EXOSC5Exosome complex component RRP46. (235 aa)
DAPK1Death-associated protein kinase 1 isoform X2. (1449 aa)
LSM14AProtein LSM14 homolog A isoform X7. (464 aa)
CPEB1Cytoplasmic polyadenylation element-binding protein 1. (561 aa)
EPRS1Bifunctional glutamate/proline--tRNA ligase isoform X2. (1511 aa)
SHMT2Serine hydroxymethyltransferase, mitochondrial. (502 aa)
NOCTNocturnin. (383 aa)
YTHDF2YTH domain-containing family protein 2. (573 aa)
NANOS2Nanos homolog 2; Belongs to the nanos family. (138 aa)
TSC1Hamartin isoform X1. (1168 aa)
YTHDF3YTH domain-containing family protein 3 isoform X2. (575 aa)
FXR1Fragile X mental retardation syndrome-related protein 1 isoform X3. (620 aa)
PDE122',5'-phosphodiesterase 12. (609 aa)
BANK1B-cell scaffold protein with ankyrin repeats isoform X4. (743 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (854 aa)
AGO1Protein argonaute-1 isoform X1; Belongs to the argonaute family. (854 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (853 aa)
METTL14N6-adenosine-methyltransferase subunit METTL14 isoform X1; Belongs to the MT-A70-like family. (468 aa)
TOB1Protein Tob1. (344 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1353 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit 1. (315 aa)
UNKRING finger protein unkempt homolog. (810 aa)
LARP1La-related protein 1 isoform X2. (954 aa)
CNOT8CCR4-NOT transcription complex subunit 8 isoform X1. (292 aa)
RIDARibonuclease UK114. (133 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (333 aa)
CNOT11CCR4-NOT transcription complex subunit 11. (512 aa)
ILF3Interleukin enhancer-binding factor 3. (892 aa)
CNOT10CCR4-NOT transcription complex subunit 10 isoform X3. (743 aa)
TRIM71E3 ubiquitin-protein ligase TRIM71. (613 aa)
DHX36ATP-dependent RNA helicase DHX36 isoform X1. (1012 aa)
RC3H2Roquin-2 isoform X1. (1191 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (283 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
TNRC6CTrinucleotide repeat-containing gene 6C protein isoform X3. (1736 aa)
CNOT9Cell differentiation protein RCD1 homolog. (299 aa)
PNLDC1poly(A)-specific ribonuclease PARN-like domain-containing protein 1 isoform X2. (530 aa)
DND1Dead end protein homolog 1. (303 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E transporter isoform X2. (980 aa)
MARF1Meiosis arrest female protein 1 isoform X2. (1742 aa)
FXR2Fragile X mental retardation syndrome-related protein 2 isoform X1. (695 aa)
SRP9Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. (62 aa)
MOV10Putative helicase MOV-10. (997 aa)
PATL1Protein PAT1 homolog 1 isoform X2. (655 aa)
CNOT6CCR4-NOT transcription complex subunit 6 isoform X1. (557 aa)
DIS3L2DIS3-like exonuclease 2 isoform X2. (801 aa)
ENSTTRP00000008635annotation not available (109 aa)
IGFBP5Insulin-like growth factor-binding protein 5. (159 aa)
MALSU1Mitochondrial assembly of ribosomal large subunit protein 1. (234 aa)
ZC3H12AEndoribonuclease ZC3H12A. (598 aa)
RC3H1Roquin-1 isoform X1. (1135 aa)
CAPRIN2Caprin-2 isoform X3. (1119 aa)
CNOT1CCR4-NOT transcription complex subunit 1 isoform X4. (2376 aa)
NANOS3Nanos C2HC-type zinc finger 3. (169 aa)
SAMD4AProtein Smaug homolog 1. (717 aa)
GRB7Growth factor receptor bound protein 7. (532 aa)
SHMT1Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (484 aa)
MEX3DRNA-binding protein MEX3D. (499 aa)
DCP1AmRNA-decapping enzyme 1A isoform X1. (532 aa)
EXOSC8Exosome complex component RRP43. (271 aa)
CAPRIN1Caprin-1 isoform X1. (665 aa)
PUM1Pumilio homolog 1 isoform X5. (1223 aa)
IGF2BP1Insulin-like growth factor 2 mRNA-binding protein 1. (577 aa)
EXOSC7Exosome complex component RRP42. (291 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1199 aa)
EIF2AK2Interferon-induced, double-stranded RNA-activated protein kinase isoform X1. (539 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (559 aa)
ZFP36L2mRNA decay activator protein ZFP36L2. (494 aa)
RNF139E3 ubiquitin-protein ligase RNF139. (664 aa)
MRPL1339S ribosomal protein L13, mitochondrial; Belongs to the universal ribosomal protein uL13 family. (178 aa)
RPS340S ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
ENSTTRP00000005476annotation not available (451 aa)
CNOT6LCCR4-NOT transcription complex subunit 6-like isoform X6. (482 aa)
RPL13A60S ribosomal protein L13a. (203 aa)
CPEB4Cytoplasmic polyadenylation element-binding protein 4 isoform X1. (729 aa)
CNOT2CCR4-NOT transcription complex subunit 2 isoform X2. (542 aa)
PABPN1LPABPN1 like, cytoplasmic. (277 aa)
SHFLShiftless antiviral inhibitor of ribosomal frameshifting. (275 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (118 aa)
SYNCRIPHeterogeneous nuclear ribonucleoprotein Q isoform X1. (623 aa)
DDX6Probable ATP-dependent RNA helicase DDX6; Belongs to the DEAD box helicase family. (483 aa)
EIF4EEukaryotic translation initiation factor 4E isoform X2; Belongs to the eukaryotic initiation factor 4E family. (211 aa)
CPEB2Cytoplasmic polyadenylation element-binding protein 2 isoform X1. (480 aa)
CALRCalreticulin. (417 aa)
ZFP36ZFP36 ring finger protein. (322 aa)
SAMD4BProtein Smaug homolog 2. (686 aa)
ZFP36L1mRNA decay activator protein ZFP36L1. (338 aa)
PLEKHN1Pleckstrin homology domain containing N1. (606 aa)
EIF4EBP2Eukaryotic translation initiation factor 4E-binding protein 2. (120 aa)
ENSTTRP00000002832annotation not available (618 aa)
AGO2Argonaute RISC catalytic component 2. (852 aa)
PARNpoly(A)-specific ribonuclease PARN isoform X2. (627 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (739 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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