STRINGSTRING
EPHA2 EPHA2 CERS3 CERS3 IRF6 IRF6 TMEM79 TMEM79 ACER1 ACER1 PAX6 PAX6 KRT80 KRT80 KRT7 KRT7 LOC101324147 LOC101324147 LOC101323852 LOC101323852 KRT85 KRT85 KRT84 KRT84 LOC109552089 LOC109552089 KRT75 KRT75 ENSTTRP00000002651 ENSTTRP00000002651 LOC101321922 LOC101321922 LOC101322971 LOC101322971 KRT5 KRT5 PPP3CA PPP3CA SCEL SCEL FOXN1 FOXN1 ENSTTRP00000004744 ENSTTRP00000004744 WNT5A WNT5A IFT74 IFT74 CYP26B1 CYP26B1 LATS1 LATS1 EXPH5 EXPH5 PALLD PALLD SHARPIN SHARPIN ENSTTRP00000006141 ENSTTRP00000006141 NOTCH1 NOTCH1 STK4 STK4 KEL KEL DNASE1L2 DNASE1L2 MED1 MED1 TGM1 TGM1 BCR BCR CLIC4 CLIC4 SAV1 SAV1 ENSTTRP00000009296 ENSTTRP00000009296 LATS2 LATS2 ANXA1 ANXA1 MAP2K1 MAP2K1 PLEC PLEC ST14 ST14 TGM3 TGM3 PNPLA1 PNPLA1 TP63 TP63 YAP1 YAP1 OPN3 OPN3 MAFB MAFB BCL11B BCL11B FOSL2 FOSL2 KRT4 KRT4 KRT78 KRT78 KRT8 KRT8 INTU INTU TSG101 TSG101 CNFN CNFN ADAM9 ADAM9 UGCG UGCG CDH3 CDH3 WNT16 WNT16 SFN SFN KDF1 KDF1 DSP DSP TXNIP TXNIP KRT17 KRT17 KRT16 KRT16 KAZN KAZN EZH2 EZH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPHA2Ephrin type-A receptor 2-like. (974 aa)
CERS3Ceramide synthase 3. (399 aa)
IRF6Interferon regulatory factor 6 isoform X2. (467 aa)
TMEM79Transmembrane protein 79. (395 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
PAX6Paired box protein Pax-6. (436 aa)
KRT80LOW QUALITY PROTEIN: keratin, type II cytoskeletal 80; Belongs to the intermediate filament family. (471 aa)
KRT7Keratin, type II cytoskeletal 7; Belongs to the intermediate filament family. (467 aa)
LOC101324147LOW QUALITY PROTEIN: keratin, type II cuticular Hb6-like; Belongs to the intermediate filament family. (192 aa)
LOC101323852Keratin, type II cuticular Hb1; Belongs to the intermediate filament family. (492 aa)
KRT85Keratin, type II cuticular Hb5-like. (504 aa)
KRT84LOW QUALITY PROTEIN: keratin, type II cuticular Hb4; Belongs to the intermediate filament family. (565 aa)
LOC109552089LOW QUALITY PROTEIN: keratin, type II cuticular Hb2-like; Belongs to the intermediate filament family. (306 aa)
KRT75LOW QUALITY PROTEIN: keratin, type II cytoskeletal 75; Belongs to the intermediate filament family. (465 aa)
ENSTTRP00000002651annotation not available (497 aa)
LOC101321922Keratin, type II cytoskeletal 6A-like; Belongs to the intermediate filament family. (559 aa)
LOC101322971LOW QUALITY PROTEIN: keratin, type II cytoskeletal 6A-like; Belongs to the intermediate filament family. (486 aa)
KRT5Keratin, type II cytoskeletal 5; Belongs to the intermediate filament family. (541 aa)
PPP3CASerine/threonine-protein phosphatase. (560 aa)
SCELSciellin isoform X1. (665 aa)
FOXN1Forkhead box protein N1 isoform X1. (645 aa)
ENSTTRP00000004744annotation not available (93 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
IFT74Intraflagellar transport protein 74 homolog isoform X1. (598 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1. (511 aa)
LATS1Serine/threonine-protein kinase LATS1. (958 aa)
EXPH5Exophilin-5 isoform X1. (1982 aa)
PALLDPalladin, cytoskeletal associated protein. (1101 aa)
SHARPINSharpin. (333 aa)
ENSTTRP00000006141annotation not available (161 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2527 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (435 aa)
KELKell blood group glycoprotein. (730 aa)
DNASE1L2Deoxyribonuclease; Belongs to the DNase I family. (296 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1512 aa)
TGM1Protein-glutamine gamma-glutamyltransferase K. (824 aa)
BCRBCR activator of RhoGEF and GTPase. (1260 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
SAV1Protein salvador homolog 1. (385 aa)
ENSTTRP00000009296annotation not available (181 aa)
LATS2Large tumor suppressor kinase 2. (992 aa)
ANXA1Annexin. (328 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (393 aa)
PLECPlectin. (4664 aa)
ST14Suppression of tumorigenicity 14. (627 aa)
TGM3Protein-glutamine gamma-glutamyltransferase E. (694 aa)
PNPLA1Patatin-like phospholipase domain-containing protein 1 isoform X2. (476 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
YAP1Transcriptional coactivator YAP1 isoform X4. (488 aa)
OPN3Opsin 3. (392 aa)
MAFBTranscription factor MafB. (323 aa)
BCL11BB-cell lymphoma/leukemia 11B. (897 aa)
FOSL2Fos-related antigen 2 isoform X5. (326 aa)
KRT4Keratin 4. (590 aa)
KRT78Keratin, type II cytoskeletal 78; Belongs to the intermediate filament family. (515 aa)
KRT8LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8-like; Belongs to the intermediate filament family. (483 aa)
INTUProtein inturned. (931 aa)
TSG101Tumor susceptibility 101. (391 aa)
CNFNCornifelin. (110 aa)
ADAM9Disintegrin and metalloproteinase domain-containing protein 9 isoform X1. (819 aa)
UGCGCeramide glucosyltransferase. (394 aa)
CDH3Cadherin-3; Cadherins are calcium-dependent cell adhesion proteins. (830 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
SFNStratifin. (248 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
DSPDesmoplakin isoform X1. (2806 aa)
TXNIPThioredoxin-interacting protein. (389 aa)
KRT17Keratin, type I cytoskeletal 17; Belongs to the intermediate filament family. (420 aa)
KRT16Keratin 16. (420 aa)
KAZNKazrin. (695 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X2. (751 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.