STRINGSTRING
TBR1 TBR1 RBFOX2 RBFOX2 HSPA5 HSPA5 EZH2 EZH2 SCRIB SCRIB PTPRS PTPRS PTF1A PTF1A NEUROD1 NEUROD1 ENSTTRP00000015833 ENSTTRP00000015833 CRK CRK GNPAT GNPAT NAGLU NAGLU SKOR2 SKOR2 SEC24B SEC24B ASCL1 ASCL1 KLHL1 KLHL1 ENSTTRP00000015243 ENSTTRP00000015243 CUNH5orf42 CUNH5orf42 BMP7 BMP7 WHRN WHRN ABL1 ABL1 ENSTTRP00000014183 ENSTTRP00000014183 XRCC1 XRCC1 OGDH OGDH KDM2B KDM2B DLL1 DLL1 SHH SHH EN2 EN2 SERPINE2 SERPINE2 GLI1 GLI1 RPGRIP1L RPGRIP1L PLXNA2 PLXNA2 CEND1 CEND1 HOXB3 HOXB3 HOXB2 HOXB2 HOXB1 HOXB1 AGTPBP1 AGTPBP1 MAFB MAFB GSX2 GSX2 TTC21B TTC21B KLHL4 KLHL4 SPTBN2 SPTBN2 NFIB NFIB ATP1B2 ATP1B2 MAP2K1 MAP2K1 EGR2 EGR2 ZNF365 ZNF365 PHOX2A PHOX2A ITGB1 ITGB1 LOC109547947 LOC109547947 GBA GBA ATRN ATRN LOC101334385 LOC101334385 CRKL CRKL PTPN11 PTPN11 LHX1 LHX1 SMO SMO ENSTTRP00000007731 ENSTTRP00000007731 KIF14 KIF14 LEF1 LEF1 SMAD1 SMAD1 KCNE1 KCNE1 SEMA4C SEMA4C RORA RORA CNTN1 CNTN1 GBX2 GBX2 PDSS2 PDSS2 TTLL1 TTLL1 GRID2 GRID2 RERE RERE NEUROD2 NEUROD2 COQ8B COQ8B ARL13B ARL13B HOXA2 HOXA2 KAT2A KAT2A HAP1 HAP1 FZD4 FZD4 CTNNB1 CTNNB1 OPHN1 OPHN1 SEZ6L2 SEZ6L2 OTX1 OTX1 AHI1 AHI1 BCL2 BCL2 POU4F1 POU4F1 WNT1 WNT1 EGF EGF MECP2 MECP2 ARCN1 ARCN1 SEZ6 SEZ6 PHOX2B PHOX2B LMX1A LMX1A PROX1 PROX1 NHLH2 NHLH2 ALDH1A2 ALDH1A2 CLP1 CLP1 NHLH1 NHLH1 HES1 HES1 B4GALT2 B4GALT2 ATF5 ATF5 EN1 EN1 FAIM2 FAIM2 CDK5 CDK5 LRRC1 LRRC1 KLHL5 KLHL5 ATF2 ATF2 NAV2 NAV2 ZNF423 ZNF423 CBLN1 CBLN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBR1T-box brain protein 1. (450 aa)
RBFOX2RNA binding protein fox-1 homolog 2 isoform X1. (389 aa)
HSPA578 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family. (654 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X2. (751 aa)
SCRIBProtein scribble homolog. (1596 aa)
PTPRSReceptor-type tyrosine-protein phosphatase S-like. (1946 aa)
PTF1APancreas transcription factor 1 subunit alpha. (326 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
ENSTTRP00000015833annotation not available (280 aa)
CRKAdapter molecule crk isoform X4. (223 aa)
GNPATGlyceronephosphate O-acyltransferase. (680 aa)
NAGLUalpha-N-acetylglucosaminidase. (744 aa)
SKOR2SKI family transcriptional corepressor 2. (296 aa)
SEC24BProtein transport protein Sec24B. (1253 aa)
ASCL1Achaete-scute homolog 1. (172 aa)
KLHL1Kelch-like protein 1 isoform X1. (750 aa)
ENSTTRP00000015243annotation not available (1080 aa)
CUNH5orf42Protein JBTS17. (2023 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
WHRNWhirlin. (901 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
ENSTTRP00000014183annotation not available (197 aa)
XRCC1DNA repair protein XRCC1 isoform X1. (598 aa)
OGDHOxoglutarate dehydrogenase. (1021 aa)
KDM2BLOW QUALITY PROTEIN: lysine-specific demethylase 2B. (1332 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (784 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
EN2Homeobox protein engrailed-2. (324 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (398 aa)
GLI1Zinc finger protein GLI1. (1106 aa)
RPGRIP1LProtein fantom. (1255 aa)
PLXNA2plexin-A2. (1909 aa)
CEND1Cell cycle exit and neuronal differentiation 1. (146 aa)
HOXB3Homeobox protein Hox-B3. (424 aa)
HOXB2Homeobox protein Hox-B2. (257 aa)
HOXB1Homeobox B1. (298 aa)
AGTPBP1Cytosolic carboxypeptidase 1 isoform X2. (1227 aa)
MAFBTranscription factor MafB. (323 aa)
GSX2GS homeobox 2. (302 aa)
TTC21BTetratricopeptide repeat protein 21B. (1281 aa)
KLHL4Kelch-like protein 4. (699 aa)
SPTBN2Spectrin beta chain, non-erythrocytic 2. (2388 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
ATP1B2ATPase Na+/K+ transporting subunit beta 2. (290 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (393 aa)
EGR2E3 SUMO-protein ligase EGR2. (455 aa)
ZNF365Protein ZNF365 isoform X2. (447 aa)
PHOX2APaired like homeobox 2A. (285 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (786 aa)
LOC109547947Cystathionine beta-synthase-like. (561 aa)
GBAGlucosylceramidase. (394 aa)
ATRNAttractin isoform X1. (1418 aa)
LOC101334385LOW QUALITY PROTEIN: protein FAM205A-like. (609 aa)
CRKLCrk-like protein. (303 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
ENSTTRP00000007731annotation not available (287 aa)
KIF14Kinesin-like protein KIF14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1509 aa)
LEF1Lymphoid enhancer binding factor 1. (396 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
KCNE1Potassium voltage-gated channel subfamily E member 1. (129 aa)
SEMA4Csemaphorin-4C. (833 aa)
RORANuclear receptor ROR-alpha isoform X5. (522 aa)
CNTN1Contactin-1 isoform X1. (937 aa)
GBX2Homeobox protein GBX-2 isoform X1. (348 aa)
PDSS2Decaprenyl-diphosphate synthase subunit 2 isoform X1; Belongs to the FPP/GGPP synthase family. (394 aa)
TTLL1Probable tubulin polyglutamylase TTLL1. (423 aa)
GRID2Glutamate receptor ionotropic, delta-2. (1008 aa)
REREArginine-glutamic acid dipeptide repeats. (1527 aa)
NEUROD2Neuronal differentiation 2. (382 aa)
COQ8BCoenzyme Q8B. (541 aa)
ARL13BADP-ribosylation factor-like protein 13B. (410 aa)
HOXA2Homeobox protein Hox-A2. (295 aa)
KAT2AHistone acetyltransferase KAT2A. (835 aa)
HAP1Huntingtin associated protein 1. (648 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
CTNNB1Catenin beta-1. (781 aa)
OPHN1Oligophrenin-1. (803 aa)
SEZ6L2Seizure 6-like protein 2. (909 aa)
OTX1Homeobox protein OTX1. (355 aa)
AHI1Jouberin isoform X1. (1168 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
POU4F1POU domain protein. (419 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
ARCN1Coatomer subunit delta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (501 aa)
SEZ6Seizure protein 6 homolog. (993 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (234 aa)
LMX1ALIM homeobox transcription factor 1-alpha. (382 aa)
PROX1Prospero homeobox protein 1. (744 aa)
NHLH2Helix-loop-helix protein 2. (135 aa)
ALDH1A2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
NHLH1Helix-loop-helix protein 1. (133 aa)
HES1Transcription factor HES-1. (280 aa)
B4GALT2Beta-1,4-galactosyltransferase 2 isoform X2. (369 aa)
ATF5Activating transcription factor 5. (278 aa)
EN1Homeobox protein engrailed-like. (400 aa)
FAIM2Fas apoptotic inhibitory molecule 2. (316 aa)
CDK5Cyclin dependent kinase 5. (292 aa)
LRRC1Leucine-rich repeat-containing protein 1 isoform X1. (522 aa)
KLHL5Kelch-like protein 5 isoform X2. (736 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
NAV2Neuron navigator 2 isoform X1. (2479 aa)
ZNF423Zinc finger protein 423. (1278 aa)
CBLN1Cerebellin-1. (192 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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