(17 nodes) Post-anal tail morphogenesis network (Tursiops truncatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSTTRP00000009086	annotation not available (269 aa)
	AXIN1	Axin-1 isoform X2. (866 aa)
	TCF15	Transcription factor 15. (197 aa)
	ENSTTRP00000006381	annotation not available (382 aa)
	FZD3	Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	MED12	Mediator of RNA polymerase II transcription subunit 12. (2173 aa)
	CHST11	Carbohydrate sulfotransferase. (350 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
	DCHS1	Protocadherin-16. (3134 aa)
	SFRP2	Secreted frizzled-related protein 2. (294 aa)
	SP5	Sp5 transcription factor. (396 aa)
	LRRC1	Leucine-rich repeat-containing protein 1 isoform X1. (522 aa)
	EPHA2	Ephrin type-A receptor 2-like. (974 aa)
	SCRIB	Protein scribble homolog. (1596 aa)
	TBXT	Brachyury protein isoform X1. (435 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	HES7	Hes family bHLH transcription factor 7. (226 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN1	ENSTTRP00000006381	ENSTTRP00000008625	ENSTTRP00000006381	Axin-1 isoform X2.	annotation not available	0.798
AXIN1	SFRP2	ENSTTRP00000008625	ENSTTRP00000004282	Axin-1 isoform X2.	Secreted frizzled-related protein 2.	0.465
AXIN1	WNT5A	ENSTTRP00000008625	ENSTTRP00000004970	Axin-1 isoform X2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.617
ENSTTRP00000006381	AXIN1	ENSTTRP00000006381	ENSTTRP00000008625	annotation not available	Axin-1 isoform X2.	0.798
ENSTTRP00000006381	FZD3	ENSTTRP00000006381	ENSTTRP00000005592	annotation not available	Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family.	0.958
ENSTTRP00000006381	SFRP2	ENSTTRP00000006381	ENSTTRP00000004282	annotation not available	Secreted frizzled-related protein 2.	0.964
FZD3	ENSTTRP00000006381	ENSTTRP00000005592	ENSTTRP00000006381	Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family.	annotation not available	0.958
FZD3	SFRP2	ENSTTRP00000005592	ENSTTRP00000004282	Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2.	0.857
FZD3	WNT5A	ENSTTRP00000005592	ENSTTRP00000004970	Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.981
LRRC1	TCF15	ENSTTRP00000000699	ENSTTRP00000006662	Leucine-rich repeat-containing protein 1 isoform X1.	Transcription factor 15.	0.464
SFRP2	AXIN1	ENSTTRP00000004282	ENSTTRP00000008625	Secreted frizzled-related protein 2.	Axin-1 isoform X2.	0.465
SFRP2	ENSTTRP00000006381	ENSTTRP00000004282	ENSTTRP00000006381	Secreted frizzled-related protein 2.	annotation not available	0.964
SFRP2	FZD3	ENSTTRP00000004282	ENSTTRP00000005592	Secreted frizzled-related protein 2.	Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family.	0.857
SFRP2	WNT5A	ENSTTRP00000004282	ENSTTRP00000004970	Secreted frizzled-related protein 2.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.949
TCF15	LRRC1	ENSTTRP00000006662	ENSTTRP00000000699	Transcription factor 15.	Leucine-rich repeat-containing protein 1 isoform X1.	0.464
WNT5A	AXIN1	ENSTTRP00000004970	ENSTTRP00000008625	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Axin-1 isoform X2.	0.617
WNT5A	FZD3	ENSTTRP00000004970	ENSTTRP00000005592	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family.	0.981
WNT5A	SFRP2	ENSTTRP00000004970	ENSTTRP00000004282	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 2.	0.949