STRINGSTRING
PQBP1 PQBP1 MCC MCC PIWIL1 PIWIL1 RC3H2 RC3H2 CASC3 CASC3 DHX36 DHX36 GABPB1 GABPB1 TRIM71 TRIM71 HELZ HELZ PASD1 PASD1 CTSH CTSH CDK9 CDK9 RNF135 RNF135 UPF2 UPF2 NUFIP2 NUFIP2 PNRC2 PNRC2 MCRIP2 MCRIP2 CNOT8 CNOT8 LARP1 LARP1 HAX1 HAX1 EIF2S1 EIF2S1 ROCK1 ROCK1 POLDIP3 POLDIP3 AGO3 AGO3 AGO1 AGO1 AGO4 AGO4 CARHSP1 CARHSP1 FXR1 FXR1 POLI POLI TIAL1 TIAL1 YTHDF3 YTHDF3 PABPC4 PABPC4 NANOS2 NANOS2 LSM2 LSM2 USP3 USP3 TDRD10 TDRD10 SHE SHE G3BP2 G3BP2 YTHDF2 YTHDF2 SHF SHF NOCT NOCT OGFOD1 OGFOD1 MEX3A MEX3A TDRD5 TDRD5 DYNC1I1 DYNC1I1 LARP1B LARP1B WTIP WTIP KIAA0355 KIAA0355 LSM14A LSM14A PIWIL2 PIWIL2 NSUN2 NSUN2 LIG4 LIG4 KHNYN KHNYN NYNRIN NYNRIN CNOT7 CNOT7 RBPMS RBPMS DDX25 DDX25 DYRK3 DYRK3 ENSTTRP00000011175 ENSTTRP00000011175 MEX3B MEX3B TNRC6B TNRC6B LSM3 LSM3 RBM4 RBM4 LARP4B LARP4B CIRBP CIRBP ASZ1 ASZ1 GIGYF2 GIGYF2 TNRC6C TNRC6C CNOT9 CNOT9 PSMC2 PSMC2 PIWIL4 PIWIL4 KHSRP KHSRP LIMD1 LIMD1 EIF4ENIF1 EIF4ENIF1 FXR2 FXR2 ELAVL1 ELAVL1 TDRD1 TDRD1 MOV10 MOV10 MBNL1 MBNL1 PATL1 PATL1 ENSTTRP00000008904 ENSTTRP00000008904 TRIM21 TRIM21 SNCAIP SNCAIP DDX4 DDX4 EDC4 EDC4 STAU2 STAU2 DIS3L2 DIS3L2 G3BP1 G3BP1 IGF2BP3 IGF2BP3 ZC3H12A ZC3H12A RC3H1 RC3H1 CNOT1 CNOT1 TDRD6 TDRD6 NANOS3 NANOS3 SAMD4A SAMD4A IGF2BP2 IGF2BP2 GRB7 GRB7 DCP1A DCP1A TRIM25 TRIM25 EDC3 EDC3 PSMA6 PSMA6 CAPRIN1 CAPRIN1 DHX9 DHX9 PABPC1L PABPC1L ZC3H12B ZC3H12B PUM1 PUM1 IGF2BP1 IGF2BP1 C19orf54 C19orf54 PAN2 PAN2 GHR GHR CNOT3 CNOT3 ENSTTRP00000006136 ENSTTRP00000006136 ARC ARC TDRD9 TDRD9 SNRPB2 SNRPB2 NFKBIZ NFKBIZ VCP VCP MAEL MAEL ATXN2L ATXN2L DDX19B DDX19B HABP4 HABP4 LOC109547085 LOC109547085 RBFOX1 RBFOX1 C9orf72 C9orf72 PMS2 PMS2 HNRNPU HNRNPU SMG1 SMG1 ZC3H12C ZC3H12C DDX1 DDX1 LOC101330346 LOC101330346 NBDY NBDY IQGAP1 IQGAP1 BTBD1 BTBD1 PUM2 PUM2 CNOT2 CNOT2 KPNB1 KPNB1 PABPC1 PABPC1 LSM6 LSM6 SHFL SHFL LSM1 LSM1 SQSTM1 SQSTM1 DDX6 DDX6 ZNFX1 ZNFX1 STAU1 STAU1 SLC39A2 SLC39A2 EIF4E EIF4E SERPINB1 SERPINB1 PRKAA2 PRKAA2 LARP4 LARP4 ZFP36 ZFP36 UHMK1 UHMK1 SAMD4B SAMD4B ZFP36L1 ZFP36L1 INA INA ICOSLG ICOSLG TDRKH TDRKH ENSTTRP00000002832 ENSTTRP00000002832 AGO2 AGO2 PAN3 PAN3 ZFAND1 ZFAND1 POLR2G POLR2G TNRC6A TNRC6A DDX3X DDX3X YTHDF1 YTHDF1 SHD SHD DCP2 DCP2 DCPS DCPS AJUBA AJUBA YBX1 YBX1 LOC101334492 LOC101334492 SNRPG SNRPG TIA1 TIA1 CLOCK CLOCK ATXN2 ATXN2 MOV10L1 MOV10L1 CHTOP CHTOP PSMA4 PSMA4 AICDA AICDA FMR1 FMR1 RPTOR RPTOR ENSTTRP00000000414 ENSTTRP00000000414 TDRD7 TDRD7 TDRD15 TDRD15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PQBP1Polyglutamine-binding protein 1. (263 aa)
MCCColorectal mutant cancer protein isoform X1. (964 aa)
PIWIL1Piwi-like protein 1; Belongs to the argonaute family. (861 aa)
RC3H2Roquin-2 isoform X1. (1191 aa)
CASC3Protein CASC3. (604 aa)
DHX36ATP-dependent RNA helicase DHX36 isoform X1. (1012 aa)
GABPB1GA-binding protein subunit beta-1 isoform X1. (392 aa)
TRIM71E3 ubiquitin-protein ligase TRIM71. (613 aa)
HELZProbable helicase with zinc finger domain isoform X2. (1940 aa)
PASD1Circadian clock protein PASD1. (620 aa)
CTSHCathepsin H. (335 aa)
CDK9Cyclin-dependent kinase 9 isoform X1; Belongs to the protein kinase superfamily. (487 aa)
RNF135LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase RNF135. (235 aa)
UPF2Regulator of nonsense transcripts 2 isoform X2. (1270 aa)
NUFIP2Nuclear fragile X mental retardation-interacting protein 2. (694 aa)
PNRC2Proline-rich nuclear receptor coactivator 2. (139 aa)
MCRIP2MAPK regulated corepressor interacting protein 2 isoform X2. (138 aa)
CNOT8CCR4-NOT transcription complex subunit 8 isoform X1. (292 aa)
LARP1La-related protein 1 isoform X2. (954 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (277 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit 1. (315 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1353 aa)
POLDIP3Polymerase delta-interacting protein 3 isoform X1. (401 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (853 aa)
AGO1Protein argonaute-1 isoform X1; Belongs to the argonaute family. (854 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (854 aa)
CARHSP1Calcium regulated heat stable protein 1. (147 aa)
FXR1Fragile X mental retardation syndrome-related protein 1 isoform X3. (620 aa)
POLIDNA polymerase iota isoform X2. (738 aa)
TIAL1Nucleolysin TIAR isoform X1. (391 aa)
YTHDF3YTH domain-containing family protein 3 isoform X2. (575 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (555 aa)
NANOS2Nanos homolog 2; Belongs to the nanos family. (138 aa)
LSM2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
USP3Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (489 aa)
TDRD10Tudor domain-containing protein 10 isoform X2. (342 aa)
SHESH2 domain-containing adapter protein E. (468 aa)
G3BP2Ras GTPase-activating protein-binding protein 2 isoform X2. (482 aa)
YTHDF2YTH domain-containing family protein 2. (573 aa)
SHFSH2 domain-containing adapter protein F. (332 aa)
NOCTNocturnin. (383 aa)
OGFOD1Prolyl 3-hydroxylase OGFOD1. (544 aa)
MEX3AMex-3 RNA binding family member A. (457 aa)
TDRD5Tudor domain-containing protein 5. (979 aa)
DYNC1I1Cytoplasmic dynein 1 intermediate chain 1. (645 aa)
LARP1BLa-related protein 1B. (914 aa)
WTIPWilms tumor protein 1-interacting protein. (292 aa)
KIAA0355Uncharacterized protein KIAA0355 homolog isoform X1. (1061 aa)
LSM14AProtein LSM14 homolog A isoform X7. (464 aa)
PIWIL2Piwi-like protein 2 isoform X1; Belongs to the argonaute family. (964 aa)
NSUN2tRNA (Cytosine(34)-C(5))-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (760 aa)
LIG4DNA ligase. (911 aa)
KHNYNProtein KHNYN. (669 aa)
NYNRINProtein NYNRIN. (484 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
RBPMSRNA-binding protein with multiple splicing isoform X1. (218 aa)
DDX25ATP-dependent RNA helicase DDX25. (483 aa)
DYRK3Dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1. (580 aa)
ENSTTRP00000011175annotation not available (505 aa)
MEX3BRNA-binding protein MEX3B. (565 aa)
TNRC6BTrinucleotide repeat-containing gene 6B protein isoform X8. (1756 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
RBM4RNA-binding protein 4 isoform X1. (363 aa)
LARP4BLa-related protein 4B isoform X1. (731 aa)
CIRBPCold-inducible RNA-binding protein. (172 aa)
ASZ1Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 isoform X1. (473 aa)
GIGYF2PERQ amino acid-rich with GYF domain-containing protein 2 isoform X1. (1290 aa)
TNRC6CTrinucleotide repeat-containing gene 6C protein isoform X3. (1736 aa)
CNOT9Cell differentiation protein RCD1 homolog. (299 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
PIWIL4Piwi-like protein 4; Belongs to the argonaute family. (850 aa)
KHSRPKH-type splicing regulatory protein. (696 aa)
LIMD1LIM domain-containing protein 1 isoform X1. (654 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E transporter isoform X2. (980 aa)
FXR2Fragile X mental retardation syndrome-related protein 2 isoform X1. (695 aa)
ELAVL1ELAV-like protein 1. (326 aa)
TDRD1Tudor domain-containing protein 1. (1189 aa)
MOV10Putative helicase MOV-10. (997 aa)
MBNL1Muscleblind-like protein 1 isoform X6. (387 aa)
PATL1Protein PAT1 homolog 1 isoform X2. (655 aa)
ENSTTRP00000008904annotation not available (193 aa)
TRIM21E3 ubiquitin-protein ligase TRIM21-like. (454 aa)
SNCAIPSynphilin-1. (1013 aa)
DDX4LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DDX4; Belongs to the DEAD box helicase family. (724 aa)
EDC4Enhancer of mRNA decapping 4. (1392 aa)
STAU2Double-stranded RNA-binding protein Staufen homolog 2 isoform X4. (570 aa)
DIS3L2DIS3-like exonuclease 2 isoform X2. (801 aa)
G3BP1Ras GTPase-activating protein-binding protein 1. (465 aa)
IGF2BP3Insulin-like growth factor 2 mRNA-binding protein 3. (579 aa)
ZC3H12AEndoribonuclease ZC3H12A. (598 aa)
RC3H1Roquin-1 isoform X1. (1135 aa)
CNOT1CCR4-NOT transcription complex subunit 1 isoform X4. (2376 aa)
TDRD6Tudor domain-containing protein 6 isoform X1. (1947 aa)
NANOS3Nanos C2HC-type zinc finger 3. (169 aa)
SAMD4AProtein Smaug homolog 1. (717 aa)
IGF2BP2Insulin-like growth factor 2 mRNA-binding protein 2. (580 aa)
GRB7Growth factor receptor bound protein 7. (532 aa)
DCP1AmRNA-decapping enzyme 1A isoform X1. (532 aa)
TRIM25E3 ubiquitin/ISG15 ligase TRIM25 isoform X1. (475 aa)
EDC3Enhancer of mRNA-decapping protein 3. (506 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
CAPRIN1Caprin-1 isoform X1. (665 aa)
DHX9ATP-dependent RNA helicase A isoform X1. (1153 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (585 aa)
ZC3H12BProbable ribonuclease ZC3H12B. (771 aa)
PUM1Pumilio homolog 1 isoform X5. (1223 aa)
IGF2BP1Insulin-like growth factor 2 mRNA-binding protein 1. (577 aa)
C19orf54Chromosome 19 open reading frame 54. (350 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1199 aa)
GHRGrowth hormone receptor. (640 aa)
CNOT3CCR4-NOT transcription complex subunit 3. (559 aa)
ENSTTRP00000006136annotation not available (91 aa)
ARCActivity-regulated cytoskeleton-associated protein. (396 aa)
TDRD9Putative ATP-dependent RNA helicase TDRD9. (906 aa)
SNRPB2U2 small nuclear ribonucleoprotein B'. (225 aa)
NFKBIZNF-kappa-B inhibitor zeta isoform X1. (720 aa)
VCPTransitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (795 aa)
MAELProtein maelstrom homolog isoform X1. (424 aa)
ATXN2LAtaxin-2-like protein. (1097 aa)
DDX19BATP-dependent RNA helicase DDX19B. (478 aa)
HABP4Intracellular hyaluronan-binding protein 4. (415 aa)
LOC109547085ATP-dependent RNA helicase DDX19A-like. (460 aa)
RBFOX1RNA binding protein fox-1 homolog; RNA-binding protein that regulates alternative splicing events. (418 aa)
C9orf72Protein C9orf72 homolog. (481 aa)
PMS2Mismatch repair endonuclease PMS2 isoform X4. (863 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform X1. (818 aa)
SMG1Serine/threonine-protein kinase SMG1 isoform X1; Belongs to the PI3/PI4-kinase family. (3627 aa)
ZC3H12CProbable ribonuclease ZC3H12C. (875 aa)
DDX1ATP-dependent RNA helicase DDX1 isoform X1. (738 aa)
LOC101330346Survival motor neuron protein. (291 aa)
NBDYNegative regulator of P-body association. (68 aa)
IQGAP1Ras GTPase-activating-like protein IQGAP1. (1658 aa)
BTBD1BTB/POZ domain-containing protein 1 isoform X1. (348 aa)
PUM2Pumilio homolog 2 isoform X1. (1063 aa)
CNOT2CCR4-NOT transcription complex subunit 2 isoform X2. (542 aa)
KPNB1Importin subunit beta-1. (843 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (620 aa)
LSM6U6 snRNA-associated Sm-like protein LSm6. (80 aa)
SHFLShiftless antiviral inhibitor of ribosomal frameshifting. (275 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
SQSTM1Sequestosome-1. (440 aa)
DDX6Probable ATP-dependent RNA helicase DDX6; Belongs to the DEAD box helicase family. (483 aa)
ZNFX1NFX1-type zinc finger-containing protein 1 isoform X1. (1918 aa)
STAU1Double-stranded RNA-binding protein Staufen homolog 1 isoform X7. (575 aa)
SLC39A2Zinc transporter ZIP2 isoform X1. (306 aa)
EIF4EEukaryotic translation initiation factor 4E isoform X2; Belongs to the eukaryotic initiation factor 4E family. (211 aa)
SERPINB1Serpin family B member 1. (377 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
LARP4La-related protein 4 isoform X1. (729 aa)
ZFP36ZFP36 ring finger protein. (322 aa)
UHMK1Serine/threonine-protein kinase Kist. (419 aa)
SAMD4BProtein Smaug homolog 2. (686 aa)
ZFP36L1mRNA decay activator protein ZFP36L1. (338 aa)
INAAlpha-internexin; Belongs to the intermediate filament family. (499 aa)
ICOSLGICOS ligand isoform X1. (424 aa)
TDRKHTudor and KH domain-containing protein isoform X1. (561 aa)
ENSTTRP00000002832annotation not available (618 aa)
AGO2Argonaute RISC catalytic component 2. (852 aa)
PAN3PAN2-PAN3 deadenylation complex subunit PAN3; Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA deca [...] (739 aa)
ZFAND1Zinc finger AN1-type containing 1. (267 aa)
POLR2GDNA-directed RNA polymerase II subunit RPB7. (172 aa)
TNRC6ATrinucleotide repeat-containing gene 6A protein isoform X9. (1955 aa)
DDX3XATP-dependent RNA helicase DDX3X; Belongs to the DEAD box helicase family. (645 aa)
YTHDF1YTH domain-containing family protein 1 isoform X2. (554 aa)
SHDSrc homology 2 domain containing transforming protein D. (340 aa)
DCP2m7GpppN-mRNA hydrolase isoform X1. (417 aa)
DCPSDecapping enzyme, scavenger. (337 aa)
AJUBALIM domain-containing protein ajuba. (537 aa)
YBX1Nuclease-sensitive element-binding protein 1 isoform X1. (316 aa)
LOC101334492DNA dC->dU-editing enzyme APOBEC-3B-like isoform X3. (178 aa)
SNRPGSmall nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (65 aa)
TIA1Nucleolysin TIA-1 isoform X1. (386 aa)
CLOCKCircadian locomoter output cycles protein kaput. (845 aa)
ATXN2Ataxin-2 isoform X5. (1270 aa)
MOV10L1Mov10 like RISC complex RNA helicase 1. (1188 aa)
CHTOPChromatin target of PRMT1 protein isoform X4. (248 aa)
PSMA4Proteasome subunit alpha type. (258 aa)
AICDASingle-stranded DNA cytosine deaminase. (182 aa)
FMR1Synaptic functional regulator FMR1 isoform X1. (597 aa)
RPTORRegulatory-associated protein of mTOR-like. (1324 aa)
ENSTTRP00000000414annotation not available (481 aa)
TDRD7Tudor domain-containing protein 7. (1099 aa)
TDRD15LOW QUALITY PROTEIN: tudor domain-containing protein 15. (1905 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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