(19 nodes) Chemoattractant activity network (Tursiops truncatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HPS5	Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1128 aa)
	VEGFD	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
	CCL16	C-C motif chemokine. (118 aa)
	LOC101330180	C-C motif chemokine. (93 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
	VEGFC	Vascular endothelial growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family. (420 aa)
	LGALS3	Galectin. (252 aa)
	LOC101326055	Beta-defensin 103-like. (67 aa)
	PGF	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family. (215 aa)
	PDGFB	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa)
	HGF	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (727 aa)
	COLEC10	Collectin-10. (227 aa)
	ENSTTRP00000007731	annotation not available (287 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	CXCL10	C-X-C motif chemokine. (92 aa)
	BMP4	Bone morphogenetic protein 4. (407 aa)
	ALKBH1	alkB homolog 1, histone H2A dioxygenase. (387 aa)
	VEGFB	Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (172 aa)
	FGF10	Fibroblast growth factor 10. (142 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	ENSTTRP00000007731	ENSTTRP00000008787	ENSTTRP00000007731	Bone morphogenetic protein 4.	annotation not available	0.763
BMP4	FGF10	ENSTTRP00000008787	ENSTTRP00000009805	Bone morphogenetic protein 4.	Fibroblast growth factor 10.	0.819
BMP4	FGF7	ENSTTRP00000008787	ENSTTRP00000008275	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.658
BMP4	HGF	ENSTTRP00000008787	ENSTTRP00000000215	Bone morphogenetic protein 4.	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.493
BMP4	WNT5A	ENSTTRP00000008787	ENSTTRP00000004970	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.591
CCL16	CXCL10	ENSTTRP00000005522	ENSTTRP00000008515	C-C motif chemokine.	C-X-C motif chemokine.	0.737
CXCL10	CCL16	ENSTTRP00000008515	ENSTTRP00000005522	C-X-C motif chemokine.	C-C motif chemokine.	0.737
CXCL10	ENSTTRP00000007731	ENSTTRP00000008515	ENSTTRP00000007731	C-X-C motif chemokine.	annotation not available	0.414
CXCL10	LOC101330180	ENSTTRP00000008515	ENSTTRP00000005464	C-X-C motif chemokine.	C-C motif chemokine.	0.889
ENSTTRP00000007731	BMP4	ENSTTRP00000007731	ENSTTRP00000008787	annotation not available	Bone morphogenetic protein 4.	0.763
ENSTTRP00000007731	CXCL10	ENSTTRP00000007731	ENSTTRP00000008515	annotation not available	C-X-C motif chemokine.	0.414
ENSTTRP00000007731	FGF10	ENSTTRP00000007731	ENSTTRP00000009805	annotation not available	Fibroblast growth factor 10.	0.544
ENSTTRP00000007731	FGF7	ENSTTRP00000007731	ENSTTRP00000008275	annotation not available	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.474
ENSTTRP00000007731	HGF	ENSTTRP00000007731	ENSTTRP00000000215	annotation not available	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.	0.752
ENSTTRP00000007731	LOC101330180	ENSTTRP00000007731	ENSTTRP00000005464	annotation not available	C-C motif chemokine.	0.523
ENSTTRP00000007731	PDGFB	ENSTTRP00000007731	ENSTTRP00000001187	annotation not available	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	0.588
ENSTTRP00000007731	PGF	ENSTTRP00000007731	ENSTTRP00000001801	annotation not available	Placenta growth factor; Belongs to the PDGF/VEGF growth factor family.	0.691
ENSTTRP00000007731	VEGFB	ENSTTRP00000007731	ENSTTRP00000009735	annotation not available	Vascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.506
ENSTTRP00000007731	VEGFC	ENSTTRP00000007731	ENSTTRP00000004737	annotation not available	Vascular endothelial growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family.	0.552
ENSTTRP00000007731	VEGFD	ENSTTRP00000007731	ENSTTRP00000006399	annotation not available	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family.	0.414