STRINGSTRING
SLC9A1 SLC9A1 DUPD1 DUPD1 MAML1 MAML1 MYO18B MYO18B TMOD1 TMOD1 PRADC1 PRADC1 PPP3CB PPP3CB SMARCD3 SMARCD3 LMOD2 LMOD2 TBX5 TBX5 ENSTTRP00000001241 ENSTTRP00000001241 MTOR MTOR MYL9 MYL9 DOCK5 DOCK5 LMNA LMNA TNNT2 TNNT2 EDNRB EDNRB ENSTTRP00000001370 ENSTTRP00000001370 HES1 HES1 HDGFL2 HDGFL2 SHOX2 SHOX2 CASQ1 CASQ1 SIK1 SIK1 KLHL41 KLHL41 DOCK2 DOCK2 EDNRA EDNRA BMP2 BMP2 CAPN3 CAPN3 WFIKKN2 WFIKKN2 SPAG9 SPAG9 PPP3CA PPP3CA MYOCD MYOCD MYOZ2 MYOZ2 SYNE1 SYNE1 MYOM2 MYOM2 TBX3 TBX3 PROX1 PROX1 NPHS1 NPHS1 R3HDM1 R3HDM1 MEF2C MEF2C DYRK1B DYRK1B ENSTTRP00000003732 ENSTTRP00000003732 HEY1 HEY1 ACTA2 ACTA2 RB1 RB1 KLF5 KLF5 ADAMTS5 ADAMTS5 CAPN2 CAPN2 TBX2 TBX2 ADPRHL1 ADPRHL1 MECP2 MECP2 WNT10B WNT10B WNT1 WNT1 TNNT3 TNNT3 ADRA1A ADRA1A SDC1 SDC1 NPNT NPNT BCL2 BCL2 SGCD SGCD PLEKHO1 PLEKHO1 HNRNPU HNRNPU SMYD3 SMYD3 MEGF10 MEGF10 SOX9 SOX9 DMD DMD CSRP3 CSRP3 TBX18 TBX18 FOXF1 FOXF1 MYL10 MYL10 ZMPSTE24 ZMPSTE24 LMOD1 LMOD1 CAV3 CAV3 CTNNB1 CTNNB1 VWA5B1 VWA5B1 ACTG1 ACTG1 ENSTTRP00000006381 ENSTTRP00000006381 MRTFB MRTFB IFRD2 IFRD2 TMOD4 TMOD4 SRF SRF PLD3 PLD3 FHOD3 FHOD3 DOCK1 DOCK1 ENSTTRP00000007008 ENSTTRP00000007008 FHL2 FHL2 NOTCH1 NOTCH1 ALPK2 ALPK2 RORA RORA NFATC2 NFATC2 LOX LOX LDB3 LDB3 KEL KEL ENSTTRP00000007431 ENSTTRP00000007431 FER1L5 FER1L5 SEMA4C SEMA4C BMPR1A BMPR1A TANC1 TANC1 FLII FLII TCAP TCAP MYOF MYOF SMO SMO CAV2 CAV2 NFATC4 NFATC4 ASB2 ASB2 WFIKKN1 WFIKKN1 BMP4 BMP4 NEBL NEBL C10orf113 C10orf113 SORT1 SORT1 ENSTTRP00000009090 ENSTTRP00000009090 PGM5 PGM5 CD9 CD9 KLHL40 KLHL40 ENSTTRP00000009296 ENSTTRP00000009296 LOC101318745 LOC101318745 SKI SKI ITGB1 ITGB1 IFT20 IFT20 KDM6B KDM6B FGF10 FGF10 PLEC PLEC COMP COMP MYORG MYORG C9orf24 C9orf24 ENSTTRP00000010071 ENSTTRP00000010071 MYH6 MYH6 MYH7 MYH7 SPG11 SPG11 ISL1 ISL1 LMOD3 LMOD3 RARB RARB CXADR CXADR TMEM182 TMEM182 NEB NEB LRRC10B LRRC10B ENSTTRP00000010661 ENSTTRP00000010661 VWA5B2 VWA5B2 MRTFA MRTFA FBXO40 FBXO40 SPEG SPEG RAMP2 RAMP2 PTCD2 PTCD2 DYSF DYSF NRAP NRAP TMEM204 TMEM204 MYOZ1 MYOZ1 SYNPO2L SYNPO2L CDON CDON ACTN1 ACTN1 NKX2-6 NKX2-6 ENSTTRP00000011747 ENSTTRP00000011747 PDGFRA PDGFRA SELENON SELENON ACTN2 ACTN2 PRKAR1A PRKAR1A KRAS KRAS NOX4 NOX4 WDR1 WDR1 ATG5 ATG5 BIN3 BIN3 PTGFRN PTGFRN STAC3 STAC3 R3HDM2 R3HDM2 CD81 CD81 MYLK3 MYLK3 MYPN MYPN GATA6 GATA6 BMP10 BMP10 SHH SHH CACNA1S CACNA1S SIX1 SIX1 SIX4 SIX4 MYOD1 MYOD1 ASF1A ASF1A ACADM ACADM MYMK MYMK ENSTTRP00000013510 ENSTTRP00000013510 ADPRH ADPRH TSC1 TSC1 POPDC2 POPDC2 GLMN GLMN MYH9 MYH9 BIN1 BIN1 CSRP2 CSRP2 FLNC FLNC ADAMTS15 ADAMTS15 KRT19 KRT19 ATP2A2 ATP2A2 ACTC1 ACTC1 MYL2 MYL2 BVES BVES POPDC3 POPDC3 APLNR APLNR ALPK3 ALPK3 ADGRB3 ADGRB3 ENSTTRP00000014726 ENSTTRP00000014726 CACNB4 CACNB4 TNNT1 TNNT1 DNER DNER MEF2A MEF2A LOC101329540 LOC101329540 RIPOR2 RIPOR2 TMOD2 TMOD2 TMOD3 TMOD3 HEY2 HEY2 ENG ENG CSRP1 CSRP1 RARA RARA IGF1 IGF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa)
DUPD1Dual specificity phosphatase and pro isomerase domain containing 1. (216 aa)
MAML1Mastermind-like protein 1. (1013 aa)
MYO18BLOW QUALITY PROTEIN: unconventional myosin-XVIIIb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2527 aa)
TMOD1Tropomodulin 1. (359 aa)
PRADC1Protease associated domain containing 1. (183 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
SMARCD3SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3. (369 aa)
LMOD2Leiomodin-2 isoform X2. (215 aa)
TBX5T-box transcription factor TBX5. (519 aa)
ENSTTRP00000001241annotation not available (390 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2442 aa)
MYL9Myosin regulatory light polypeptide 9. (172 aa)
DOCK5Dedicator of cytokinesis protein 5 isoform X1; Belongs to the DOCK family. (1865 aa)
LMNALamin A/C. (664 aa)
TNNT2Troponin T, cardiac muscle. (283 aa)
EDNRBEndothelin B receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (530 aa)
ENSTTRP00000001370annotation not available (184 aa)
HES1Transcription factor HES-1. (280 aa)
HDGFL2Hepatoma-derived growth factor-related protein 2 isoform X1. (664 aa)
SHOX2LOW QUALITY PROTEIN: short stature homeobox protein 2. (282 aa)
CASQ1Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (398 aa)
SIK1Serine/threonine-protein kinase SIK1 isoform X1. (718 aa)
KLHL41Bardet-Biedl syndrome 5 protein isoform X2. (606 aa)
DOCK2Dedicator of cytokinesis protein 2 isoform X1; Belongs to the DOCK family. (1810 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
CAPN3Calpain-3; Belongs to the peptidase C2 family. (822 aa)
WFIKKN2WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2. (574 aa)
SPAG9C-Jun-amino-terminal kinase-interacting protein 4 isoform X2. (1316 aa)
PPP3CASerine/threonine-protein phosphatase. (560 aa)
MYOCDMyocardin isoform X1. (968 aa)
MYOZ2Myozenin-2. (264 aa)
SYNE1Nesprin-1 isoform X1. (8745 aa)
MYOM2Myomesin 2. (1463 aa)
TBX3T-box transcription factor TBX3. (742 aa)
PROX1Prospero homeobox protein 1. (744 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1240 aa)
R3HDM1R3H domain-containing protein 1 isoform X5. (1096 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (472 aa)
DYRK1BDual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X2. (629 aa)
ENSTTRP00000003732annotation not available (574 aa)
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1. (193 aa)
ACTA2Actin, aortic smooth muscle. (378 aa)
RB1Retinoblastoma-associated protein. (922 aa)
KLF5Krueppel-like factor 5. (370 aa)
ADAMTS5A disintegrin and metalloproteinase with thrombospondin motifs 5. (931 aa)
CAPN2Calpain-2 catalytic subunit; Belongs to the peptidase C2 family. (700 aa)
TBX2T-box transcription factor TBX2. (703 aa)
ADPRHL1Protein ADP-ribosylarginine hydrolase-like protein 1. (353 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TNNT3Troponin T3, fast skeletal type. (254 aa)
ADRA1Aalpha-1A adrenergic receptor. (423 aa)
SDC1Syndecan 1. (295 aa)
NPNTNephronectin isoform X2. (560 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
SGCDDelta-sarcoglycan. (289 aa)
PLEKHO1Pleckstrin homology domain containing O1. (435 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U isoform X1. (818 aa)
SMYD3Histone-lysine N-methyltransferase SMYD3 isoform X2. (428 aa)
MEGF10Multiple epidermal growth factor-like domains protein 10. (1137 aa)
SOX9Transcription factor SOX-9. (509 aa)
DMDDystrophin. (3674 aa)
CSRP3Cysteine and glycine-rich protein 3. (192 aa)
TBX18T-box transcription factor TBX18. (612 aa)
FOXF1Forkhead box F1. (372 aa)
MYL10Myosin light chain 10. (117 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
LMOD1Leiomodin 1. (610 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (192 aa)
CTNNB1Catenin beta-1. (781 aa)
VWA5B1Von Willebrand factor A domain containing 5B1. (1212 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
ENSTTRP00000006381annotation not available (382 aa)
MRTFBMKL/myocardin-like protein 2 isoform X3. (969 aa)
IFRD2Interferon-related developmental regulator 2 isoform X2. (584 aa)
TMOD4Tropomodulin-4. (342 aa)
SRFSerum response factor isoform X2. (509 aa)
PLD3Phospholipase D3. (490 aa)
FHOD3LOW QUALITY PROTEIN: FH1/FH2 domain-containing protein 3. (1437 aa)
DOCK1Dedicator of cytokinesis protein 1 isoform X2; Belongs to the DOCK family. (1926 aa)
ENSTTRP00000007008annotation not available (158 aa)
FHL2Four and a half LIM domains protein 2 isoform X1. (362 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2527 aa)
ALPK2Alpha-protein kinase 2. (2163 aa)
RORANuclear receptor ROR-alpha isoform X5. (522 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X2. (919 aa)
LOXLysyl oxidase. (411 aa)
LDB3LIM domain-binding protein 3 isoform X2. (724 aa)
KELKell blood group glycoprotein. (730 aa)
ENSTTRP00000007431annotation not available (141 aa)
FER1L5Fer-1-like protein 5. (795 aa)
SEMA4Csemaphorin-4C. (833 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
TANC1Protein TANC1 isoform X1. (1862 aa)
FLIIProtein flightless-1 homolog. (1264 aa)
TCAPTitin-cap. (167 aa)
MYOFMyoferlin isoform X3. (2056 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
NFATC4Nuclear factor of activated T cells 4. (746 aa)
ASB2Ankyrin repeat and SOCS box protein 2 isoform X1. (585 aa)
WFIKKN1WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1. (550 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
NEBLNebulette isoform X2. (1011 aa)
C10orf113Uncharacterized protein. (141 aa)
SORT1Sortilin. (831 aa)
ENSTTRP00000009090annotation not available (334 aa)
PGM5Phosphoglucomutase-like protein 5; Belongs to the phosphohexose mutase family. (480 aa)
CD9Tetraspanin. (205 aa)
KLHL40Kelch-like protein 40. (622 aa)
ENSTTRP00000009296annotation not available (181 aa)
LOC101318745Histone H3.3-like. (136 aa)
SKISki oncogene. (633 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (786 aa)
IFT20LOW QUALITY PROTEIN: intraflagellar transport protein 20 homolog. (158 aa)
KDM6BDynein heavy chain 2, axonemal. (1642 aa)
FGF10Fibroblast growth factor 10. (142 aa)
PLECPlectin. (4664 aa)
COMPCartilage oligomeric matrix protein. (756 aa)
MYORGUncharacterized family 31 glucosidase KIAA1161 homolog isoform X2; Belongs to the glycosyl hydrolase 31 family. (630 aa)
C9orf24Spermatid-specific manchette-related protein 1 isoform X1. (261 aa)
ENSTTRP00000010071annotation not available (254 aa)
MYH6Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1934 aa)
MYH7Myosin-7-like. (1896 aa)
SPG11Spatacsin isoform X2. (2435 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
LMOD3Leiomodin-3. (566 aa)
RARBRetinoic acid receptor beta. (522 aa)
CXADRCoxsackievirus and adenovirus receptor isoform X1. (365 aa)
TMEM182Transmembrane protein 182 isoform X2. (217 aa)
NEBNebulin. (6623 aa)
LRRC10BLeucine-rich repeat-containing protein 10B. (242 aa)
ENSTTRP00000010661annotation not available (123 aa)
VWA5B2Von Willebrand factor A domain-containing protein 5B2 isoform X2. (1007 aa)
MRTFAPhosphatase and actin regulator. (925 aa)
FBXO40F-box only protein 40. (676 aa)
SPEGStriated muscle enriched protein kinase. (3256 aa)
RAMP2Receptor activity modifying protein 2. (176 aa)
PTCD2Pentatricopeptide repeat-containing protein 2, mitochondrial. (388 aa)
DYSFDysferlin-like. (2076 aa)
NRAPNebulin-related-anchoring protein. (1729 aa)
TMEM204Transmembrane protein 204. (225 aa)
MYOZ1Myozenin-1 isoform X1. (298 aa)
SYNPO2LSynaptopodin 2 like. (974 aa)
CDONCell adhesion molecule-related/down-regulated by oncogenes. (1273 aa)
ACTN1Alpha-actinin-1. (913 aa)
NKX2-6Homeobox protein Nkx-2.6. (299 aa)
ENSTTRP00000011747annotation not available (136 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1040 aa)
SELENONSelenoprotein N. (564 aa)
ACTN2Alpha-actinin-2 isoform X2. (891 aa)
PRKAR1AcAMP-dependent protein kinase type I-alpha regulatory subunit. (380 aa)
KRASGTPase KRas. (189 aa)
NOX4NADPH oxidase 4. (577 aa)
WDR1WD repeat domain 1. (607 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
BIN3Bridging integrator 3. (251 aa)
PTGFRNProstaglandin F2 receptor inhibitor. (927 aa)
STAC3SH3 and cysteine-rich domain-containing protein 3 isoform X1. (340 aa)
R3HDM2R3H domain-containing protein 2 isoform X2. (1034 aa)
CD81CD81 molecule. (214 aa)
MYLK3Myosin light chain kinase 3. (800 aa)
MYPNMyopalladin. (1296 aa)
GATA6Transcription factor GATA-6. (592 aa)
BMP10Bone morphogenetic protein 10. (423 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha-1S-like. (1856 aa)
SIX1Homeobox protein SIX1. (284 aa)
SIX4Homeobox protein SIX4. (494 aa)
MYOD1Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (319 aa)
ASF1AHistone chaperone ASF1A isoform X2. (168 aa)
ACADMMedium-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1. (454 aa)
MYMKMyomaker, myoblast fusion factor. (221 aa)
ENSTTRP00000013510annotation not available (503 aa)
ADPRHADP-ribosylarginine hydrolase isoform X2. (339 aa)
TSC1Hamartin isoform X1. (1168 aa)
POPDC2Popeye domain-containing protein 2 isoform X2. (365 aa)
GLMNGlomulin. (589 aa)
MYH9Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1885 aa)
BIN1Myc box-dependent-interacting protein 1. (594 aa)
CSRP2Cysteine and glycine-rich protein 2. (193 aa)
FLNCFilamin C. (2716 aa)
ADAMTS15A disintegrin and metalloproteinase with thrombospondin motifs 15. (950 aa)
KRT19Keratin 19. (400 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1041 aa)
ACTC1Actin alpha cardiac muscle 1. (376 aa)
MYL2Myosin regulatory light chain 2, ventricular/cardiac muscle isoform. (166 aa)
BVESBlood vessel epicardial substance. (360 aa)
POPDC3Popeye domain-containing protein 3. (290 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
ALPK3Alpha-protein kinase 3 isoform X1. (1851 aa)
ADGRB3Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1521 aa)
ENSTTRP00000014726annotation not available (263 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4. (520 aa)
TNNT1Troponin T, slow skeletal muscle. (268 aa)
DNERDelta and Notch-like epidermal growth factor-related receptor. (738 aa)
MEF2AMyocyte-specific enhancer factor 2A isoform X2. (498 aa)
LOC101329540Histone H3; Belongs to the histone H3 family. (136 aa)
RIPOR2Protein FAM65B isoform X7. (1064 aa)
TMOD2Tropomodulin-2 isoform X2. (351 aa)
TMOD3Tropomodulin-3 isoform X1. (309 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (336 aa)
ENGEndoglin. (655 aa)
CSRP1Cysteine and glycine-rich protein 1. (193 aa)
RARARetinoic acid receptor alpha-like. (618 aa)
IGF1Insulin-like growth factor 1 transcript variant X4. (194 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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