STRINGSTRING
HEY1 HEY1 HES1 HES1 PAX6 PAX6 NEPRO NEPRO FEZF2 FEZF2 MIB1 MIB1 APP APP CALR CALR GLI3 GLI3 LMX1A LMX1A REST REST PHOX2B PHOX2B EIF4E EIF4E DDX6 DDX6 LSM1 LSM1 SOX9 SOX9 SOX8 SOX8 JAG1 JAG1 HMG20A HMG20A CNTN2 CNTN2 ENSTTRP00000006381 ENSTTRP00000006381 HOXA2 HOXA2 CDK5RAP2 CDK5RAP2 POU4F2 POU4F2 NOTCH1 NOTCH1 DLX6 DLX6 TTC3 TTC3 CNTN4 CNTN4 TLX3 TLX3 MED1 MED1 NR2E1 NR2E1 NKX2-2 NKX2-2 GDF11 GDF11 ENSTTRP00000009296 ENSTTRP00000009296 ZNF536 ZNF536 ITGB1 ITGB1 EIF4ENIF1 EIF4ENIF1 DIXDC1 DIXDC1 LOC101333926 LOC101333926 ISL1 ISL1 GPR37L1 GPR37L1 DLX1 DLX1 DLX2 DLX2 ISL2 ISL2 CTDSP1 CTDSP1 SHH SHH DLL1 DLL1 MEIS2 MEIS2 MEIS1 MEIS1 LBX1 LBX1 BMP7 BMP7 DISP3 DISP3 ASCL1 ASCL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HEY1Hairy/enhancer-of-split related with YRPW motif protein 1 isoform X1. (193 aa)
HES1Transcription factor HES-1. (280 aa)
PAX6Paired box protein Pax-6. (436 aa)
NEPRONucleolus and neural progenitor protein isoform X1. (563 aa)
FEZF2Fez family zinc finger protein 2. (457 aa)
MIB1E3 ubiquitin-protein ligase MIB1. (1006 aa)
APPAmyloid beta A4 protein isoform X1. (763 aa)
CALRCalreticulin. (417 aa)
GLI3Transcriptional activator GLI3. (1580 aa)
LMX1ALIM homeobox transcription factor 1-alpha. (382 aa)
RESTRE1-silencing transcription factor. (656 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (234 aa)
EIF4EEukaryotic translation initiation factor 4E isoform X2; Belongs to the eukaryotic initiation factor 4E family. (211 aa)
DDX6Probable ATP-dependent RNA helicase DDX6; Belongs to the DEAD box helicase family. (483 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (133 aa)
SOX9Transcription factor SOX-9. (509 aa)
SOX8Transcription factor SOX-8. (445 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
HMG20AHigh mobility group protein 20A. (346 aa)
CNTN2Contactin 2. (1001 aa)
ENSTTRP00000006381annotation not available (382 aa)
HOXA2Homeobox protein Hox-A2. (295 aa)
CDK5RAP2LOW QUALITY PROTEIN: CDK5 regulatory subunit-associated protein 2. (1890 aa)
POU4F2POU class 4 homeobox 2. (409 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2527 aa)
DLX6Homeobox protein DLX-6. (232 aa)
TTC3E3 ubiquitin-protein ligase TTC3-like isoform X1. (1934 aa)
CNTN4Contactin-4. (1026 aa)
TLX3T-cell leukemia homeobox protein 3. (291 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1512 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (419 aa)
NKX2-2Homeobox protein Nkx-2.2. (271 aa)
GDF11Growth differentiation factor 11. (313 aa)
ENSTTRP00000009296annotation not available (181 aa)
ZNF536Zinc finger protein 536. (1298 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (786 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E transporter isoform X2. (980 aa)
DIXDC1Dixin isoform X1. (650 aa)
LOC101333926RE1-silencing transcription factor-like. (974 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
GPR37L1Prosaposin receptor GPR37L1. (462 aa)
DLX1Distal-less homeobox 1. (255 aa)
DLX2Homeobox protein DLX-2. (281 aa)
ISL2Insulin gene enhancer protein ISL-2. (324 aa)
CTDSP1Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1. (261 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (784 aa)
MEIS2Homeobox protein Meis2 isoform X1. (345 aa)
MEIS1Homeobox protein Meis1 isoform X2. (463 aa)
LBX1Transcription factor LBX1. (281 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
DISP3Dispatched RND transporter family member 3. (1437 aa)
ASCL1Achaete-scute homolog 1. (172 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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