STRINGSTRING
LRP3 LRP3 ENSTTRP00000011869 ENSTTRP00000011869 HDAC7 HDAC7 GLI1 GLI1 GDF10 GDF10 NOCT NOCT PRKD1 PRKD1 ATF4 ATF4 PRKACA PRKACA TWSG1 TWSG1 SMOC1 SMOC1 BMPR1B BMPR1B BMP7 BMP7 CTHRC1 CTHRC1 BMP6 BMP6 IL6ST IL6ST ID3 ID3 SMAD5 SMAD5 ACVR2A ACVR2A LRP5 LRP5 SUCO SUCO FBN2 FBN2 LTF LTF IGF1 IGF1 WNT10B WNT10B SFRP2 SFRP2 FERMT2 FERMT2 TENT5A TENT5A CEBPB CEBPB MEF2C MEF2C TCIRG1 TCIRG1 REST REST GLI3 GLI3 WWTR1 WWTR1 SEMA4D SEMA4D HDAC4 HDAC4 BAMBI BAMBI CTNNBIP1 CTNNBIP1 SMAD3 SMAD3 PPP3CA PPP3CA TOB1 TOB1 ZHX3 ZHX3 BMP2 BMP2 TNFAIP6 TNFAIP6 HAND2 HAND2 CYR61 CYR61 WDR63 WDR63 SFRP1 SFRP1 FBXO5 FBXO5 WISP1 WISP1 ILK ILK NPNT NPNT BMPR2 BMPR2 VEGFC VEGFC SOX11 SOX11 CRIM1 CRIM1 SOX9 SOX9 CTNNB1 CTNNB1 JAG1 JAG1 JUND JUND SCUBE2 SCUBE2 HOXA2 HOXA2 RUNX2 RUNX2 NOTCH1 NOTCH1 GDPD2 GDPD2 SMAD1 SMAD1 BMPR1A BMPR1A ENSTTRP00000007731 ENSTTRP00000007731 RANBP3L RANBP3L FFAR4 FFAR4 RORB RORB OSTN OSTN LOC101330177 LOC101330177 MEN1 MEN1 RASSF2 RASSF2 BMP4 BMP4 AXIN2 AXIN2 SCUBE3 SCUBE3 PDLIM7 PDLIM7 FNDC3B FNDC3B ENSTTRP00000009296 ENSTTRP00000009296 SKI SKI SMAD6 SMAD6 LIMD1 LIMD1 TNN TNN HEMGN HEMGN LOC101333926 LOC101333926 PTCH1 PTCH1 DDR2 DDR2 UCMA UCMA CHRD CHRD CDK6 CDK6 TP63 TP63 YAP1 YAP1 NBR1 NBR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRP3Low-density lipoprotein receptor-related protein 3 isoform X1. (750 aa)
ENSTTRP00000011869annotation not available (286 aa)
HDAC7Histone deacetylase 7. (983 aa)
GLI1Zinc finger protein GLI1. (1106 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (476 aa)
NOCTNocturnin. (383 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (876 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (351 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
SMOC1SPARC related modular calcium binding 1. (432 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
CTHRC1Collagen triple helix repeat-containing protein 1. (197 aa)
BMP6Bone morphogenetic protein 6. (304 aa)
IL6STInterleukin-6 receptor subunit beta isoform X1. (918 aa)
ID3DNA-binding protein inhibitor ID-3. (119 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
LRP5LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5. (1582 aa)
SUCOSUN domain-containing ossification factor isoform X8. (1366 aa)
FBN2Fibrillin-2. (2776 aa)
LTFLactotransferrin isoform X1; Belongs to the transferrin family. (708 aa)
IGF1Insulin-like growth factor 1 transcript variant X4. (194 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
FERMT2Fermitin family homolog 2. (614 aa)
TENT5AProtein FAM46A. (521 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (472 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (826 aa)
RESTRE1-silencing transcription factor. (656 aa)
GLI3Transcriptional activator GLI3. (1580 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
SEMA4Dsemaphorin-4D isoform X1; Belongs to the semaphorin family. (863 aa)
HDAC4Histone deacetylase 4. (1065 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (234 aa)
CTNNBIP1Beta-catenin-interacting protein 1 isoform X1. (176 aa)
SMAD3Mothers against decapentaplegic homolog 3. (291 aa)
PPP3CASerine/threonine-protein phosphatase. (560 aa)
TOB1Protein Tob1. (344 aa)
ZHX3Zinc fingers and homeoboxes protein 3 isoform X2. (952 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
TNFAIP6Tumor necrosis factor-inducible gene 6 protein isoform X2. (277 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (208 aa)
CYR61Protein CYR61. (382 aa)
WDR63WD repeat-containing protein 63. (891 aa)
SFRP1Secreted frizzled-related protein 1 isoform X2. (307 aa)
FBXO5F-box only protein 5 isoform X1. (448 aa)
WISP1WNT1-inducible-signaling pathway protein 1. (259 aa)
ILKIntegrin-linked protein kinase. (450 aa)
NPNTNephronectin isoform X2. (560 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
VEGFCVascular endothelial growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family. (420 aa)
SOX11Transcription factor SOX. (309 aa)
CRIM1Cysteine-rich motor neuron 1 protein isoform X1. (1025 aa)
SOX9Transcription factor SOX-9. (509 aa)
CTNNB1Catenin beta-1. (781 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (345 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1. (995 aa)
HOXA2Homeobox protein Hox-A2. (295 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (587 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2527 aa)
GDPD2Glycerophosphoinositol inositolphosphodiesterase GDPD2. (520 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
ENSTTRP00000007731annotation not available (287 aa)
RANBP3LRan-binding protein 3-like. (466 aa)
FFAR4Free fatty acid receptor 4. (377 aa)
RORBNuclear receptor ROR-beta isoform X1. (519 aa)
OSTNOsteocrin. (128 aa)
LOC101330177Extracellular serine/threonine protein kinase FAM20C. (259 aa)
MEN1Menin 1. (615 aa)
RASSF2Ras association domain-containing protein 2. (326 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
AXIN2Axin-2-like. (839 aa)
SCUBE3Signal peptide, CUB and EGF-like domain-containing protein 1. (1007 aa)
PDLIM7PDZ and LIM domain protein 7. (458 aa)
FNDC3BFibronectin type III domain-containing protein 3B isoform X4. (1203 aa)
ENSTTRP00000009296annotation not available (181 aa)
SKISki oncogene. (633 aa)
SMAD6SMAD family member 6. (492 aa)
LIMD1LIM domain-containing protein 1 isoform X1. (654 aa)
TNNtenascin-N. (1241 aa)
HEMGNHemogen isoform X1. (443 aa)
LOC101333926RE1-silencing transcription factor-like. (974 aa)
PTCH1Protein patched homolog 1 isoform X1. (1313 aa)
DDR2Discoidin domain-containing receptor 2. (853 aa)
UCMAUnique cartilage matrix-associated protein. (138 aa)
CHRDChordin. (908 aa)
CDK6Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
YAP1Transcriptional coactivator YAP1 isoform X4. (488 aa)
NBR1Next to BRCA1 gene 1 protein isoform X1. (478 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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