STRINGSTRING
IGF1 IGF1 WISP1 WISP1 FBXO5 FBXO5 WDR63 WDR63 CYR61 CYR61 BMP2 BMP2 ZHX3 ZHX3 PPP3CA PPP3CA CTNNBIP1 CTNNBIP1 WWTR1 WWTR1 GLI3 GLI3 MEF2C MEF2C CEBPB CEBPB TENT5A TENT5A FERMT2 FERMT2 SFRP2 SFRP2 WNT10B WNT10B ILK ILK NPNT NPNT BMPR2 BMPR2 SOX11 SOX11 CTNNB1 CTNNB1 JAG1 JAG1 JUND JUND SCUBE2 SCUBE2 RUNX2 RUNX2 GDPD2 GDPD2 SMAD1 SMAD1 BMPR1A BMPR1A ENSTTRP00000007731 ENSTTRP00000007731 FFAR4 FFAR4 LOC101330177 LOC101330177 BMP4 BMP4 SCUBE3 SCUBE3 PDLIM7 PDLIM7 DDR2 DDR2 TP63 TP63 YAP1 YAP1 LRP3 LRP3 ENSTTRP00000011869 ENSTTRP00000011869 PRKD1 PRKD1 BMPR1B BMPR1B BMP7 BMP7 CTHRC1 CTHRC1 BMP6 BMP6 IL6ST IL6ST SMAD5 SMAD5 ACVR2A ACVR2A LRP5 LRP5 SUCO SUCO FBN2 FBN2 LTF LTF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IGF1Insulin-like growth factor 1 transcript variant X4. (194 aa)
WISP1WNT1-inducible-signaling pathway protein 1. (259 aa)
FBXO5F-box only protein 5 isoform X1. (448 aa)
WDR63WD repeat-containing protein 63. (891 aa)
CYR61Protein CYR61. (382 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
ZHX3Zinc fingers and homeoboxes protein 3 isoform X2. (952 aa)
PPP3CASerine/threonine-protein phosphatase. (560 aa)
CTNNBIP1Beta-catenin-interacting protein 1 isoform X1. (176 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
GLI3Transcriptional activator GLI3. (1580 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (472 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
TENT5AProtein FAM46A. (521 aa)
FERMT2Fermitin family homolog 2. (614 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
ILKIntegrin-linked protein kinase. (450 aa)
NPNTNephronectin isoform X2. (560 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
SOX11Transcription factor SOX. (309 aa)
CTNNB1Catenin beta-1. (781 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
JUNDJunD proto-oncogene, AP-1 transcription factor subunit. (345 aa)
SCUBE2Signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1. (995 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (587 aa)
GDPD2Glycerophosphoinositol inositolphosphodiesterase GDPD2. (520 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
ENSTTRP00000007731annotation not available (287 aa)
FFAR4Free fatty acid receptor 4. (377 aa)
LOC101330177Extracellular serine/threonine protein kinase FAM20C. (259 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
SCUBE3Signal peptide, CUB and EGF-like domain-containing protein 1. (1007 aa)
PDLIM7PDZ and LIM domain protein 7. (458 aa)
DDR2Discoidin domain-containing receptor 2. (853 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
YAP1Transcriptional coactivator YAP1 isoform X4. (488 aa)
LRP3Low-density lipoprotein receptor-related protein 3 isoform X1. (750 aa)
ENSTTRP00000011869annotation not available (286 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (876 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
CTHRC1Collagen triple helix repeat-containing protein 1. (197 aa)
BMP6Bone morphogenetic protein 6. (304 aa)
IL6STInterleukin-6 receptor subunit beta isoform X1. (918 aa)
SMAD5Mothers against decapentaplegic homolog. (465 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
LRP5LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5. (1582 aa)
SUCOSUN domain-containing ossification factor isoform X8. (1366 aa)
FBN2Fibrillin-2. (2776 aa)
LTFLactotransferrin isoform X1; Belongs to the transferrin family. (708 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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