STRINGSTRING
FOXF1 FOXF1 GLI3 GLI3 SHOX2 SHOX2 SIX2 SIX2 NIPBL NIPBL SHH SHH PDGFRA PDGFRA FGF10 FGF10 IHH IHH TCF21 TCF21 ID2 ID2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FOXF1Forkhead box F1. (372 aa)
GLI3Transcriptional activator GLI3. (1580 aa)
SHOX2LOW QUALITY PROTEIN: short stature homeobox protein 2. (282 aa)
SIX2Homeobox protein SIX2. (168 aa)
NIPBLNipped-B protein. (2801 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1040 aa)
FGF10Fibroblast growth factor 10. (142 aa)
IHHIndian hedgehog protein. (409 aa)
TCF21Transcription factor 21. (162 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.