STRINGSTRING
HOXD13 HOXD13 RXFP2 RXFP2 SIX4 SIX4 VASH2 VASH2 BPTF BPTF MSH4 MSH4 DMRT1 DMRT1 WDR19 WDR19 DAZAP1 DAZAP1 GRB2 GRB2 CYP27C1 CYP27C1 PTX3 PTX3 KRT19 KRT19 DLG2 DLG2 CCDC134 CCDC134 DHCR24 DHCR24 FGF8 FGF8 STK11 STK11 CDKN1B CDKN1B BMPR1B BMPR1B AGO4 AGO4 SALL1 SALL1 HS6ST1 HS6ST1 DMRTA1 DMRTA1 PKD2 PKD2 GCM1 GCM1 TMF1 TMF1 KIT KIT LHX8 LHX8 IGF2 IGF2 ZNF830 ZNF830 PKD1 PKD1 BMP7 BMP7 SPO11 SPO11 NUP107 NUP107 SETD2 SETD2 LOC101329540 LOC101329540 BMP6 BMP6 GAS2 GAS2 FEM1B FEM1B NIPBL NIPBL SCAPER SCAPER SIRT1 SIRT1 HEY2 HEY2 MDFI MDFI MERTK MERTK EGLN1 EGLN1 KITLG KITLG MAPK1 MAPK1 PLAG1 PLAG1 GPR149 GPR149 RARA RARA FOSL1 FOSL1 SP3 SP3 FOXO3 FOXO3 NR5A1 NR5A1 ASB1 ASB1 E2F7 E2F7 NOTCH2 NOTCH2 TPPP3 TPPP3 FGF9 FGF9 SOCS3 SOCS3 ENSTTRP00000000710 ENSTTRP00000000710 KDM5B KDM5B SFRP1 SFRP1 NSDHL NSDHL RBM15 RBM15 CYR61 CYR61 TNFAIP6 TNFAIP6 LIF LIF LEP LEP HES1 HES1 HSD17B3 HSD17B3 BIRC6 BIRC6 EPOR EPOR COL9A3 COL9A3 NHLH1 NHLH1 EIF2B2 EIF2B2 TRIM28 TRIM28 SPATA2 SPATA2 SNAI1 SNAI1 ETV2 ETV2 CSMD2 CSMD2 IMMP2L IMMP2L KDR KDR HAND1 HAND1 RARG RARG TYRO3 TYRO3 FOXA1 FOXA1 MYOCD MYOCD ESR1 ESR1 EIF2B5 EIF2B5 TIPARP TIPARP NHLH2 NHLH2 NODAL NODAL TBX3 TBX3 ENSTTRP00000003065 ENSTTRP00000003065 ENSTTRP00000003132 ENSTTRP00000003132 LHCGR LHCGR FSHR FSHR ZFP36L1 ZFP36L1 HOXA11 HOXA11 JUNB JUNB INHBA INHBA WNT9B WNT9B ZFAT ZFAT HECTD1 HECTD1 RSPO3 RSPO3 CEBPB CEBPB STRA6 STRA6 SLIT3 SLIT3 AR AR MSH2 MSH2 CHD7 CHD7 ATRX ATRX FANCA FANCA SFRP2 SFRP2 BRIP1 BRIP1 GATA1 GATA1 VGF VGF DHH DHH ATN1 ATN1 PTPN6 PTPN6 GREB1L GREB1L TAF10 TAF10 BMPR2 BMPR2 GATA3 GATA3 BCL2 BCL2 TBC1D20 TBC1D20 SERPINB5 SERPINB5 PLEKHA1 PLEKHA1 HTRA1 HTRA1 WNT5A WNT5A PCYT1B PCYT1B TNC TNC DMC1 DMC1 SOX9 SOX9 SRC SRC E2F8 E2F8 SLIT2 SLIT2 FOXF2 FOXF2 GRHL2 GRHL2 SOX8 SOX8 TFAP2C TFAP2C UBE3A UBE3A ATM ATM BCL2L11 BCL2L11 CTNNB1 CTNNB1 WDR48 WDR48 TIFAB TIFAB CITED1 CITED1 NRIP1 NRIP1 FZD4 FZD4 PLCD3 PLCD3 STK3 STK3 FANCG FANCG RTCB RTCB SCX SCX LRP2 LRP2 AFP AFP EIF2S2 EIF2S2 KLHL10 KLHL10 STAT5B STAT5B HSD17B2 HSD17B2 SERPINF1 SERPINF1 HYAL3 HYAL3 BAK1 BAK1 CSF2 CSF2 CUL7 CUL7 AXL AXL LRRC6 LRRC6 STAT5A STAT5A HOXB13 HOXB13 BIK BIK ARNT ARNT GHRL GHRL LHX3 LHX3 SGPL1 SGPL1 NOTCH1 NOTCH1 STK4 STK4 ADAMTS1 ADAMTS1 YBX3 YBX3 LEF1 LEF1 ERCC1 ERCC1 CYP27B1 CYP27B1 HNF1A HNF1A MED1 MED1 REC8 REC8 PTN PTN BCL2L2 BCL2L2 ETNK2 ETNK2 REN REN SF1 SF1 LHX1 LHX1 PTPN11 PTPN11 HESX1 HESX1 CRKL CRKL TAF4 TAF4 RDH10 RDH10 BMP4 BMP4 LOC101336078 LOC101336078 ALKBH1 ALKBH1 BMP15 BMP15 STOX2 STOX2 PPARD PPARD ENSTTRP00000008984 ENSTTRP00000008984 NKX2-1 NKX2-1 ING2 ING2 TCF21 TCF21 PHLDA2 PHLDA2 SPINT2 SPINT2 ENSTTRP00000009296 ENSTTRP00000009296 LOC101318745 LOC101318745 OSR1 OSR1 WNT2B WNT2B ARID5B ARID5B PTPRN PTPRN ANXA1 ANXA1 ADGRG1 ADGRG1 ENSTTRP00000009655 ENSTTRP00000009655 MAP2K1 MAP2K1 SOX15 SOX15 PATZ1 PATZ1 WNT2 WNT2 FGF10 FGF10 KIF18A KIF18A ST14 ST14 BRCA2 BRCA2 FBXW8 FBXW8 CDX4 CDX4 PRDX3 PRDX3 GFRA1 GFRA1 RAB13 RAB13 SYCP2 SYCP2 SPINT1 SPINT1 EAF2 EAF2 TP63 TP63 SMAD4 SMAD4 EPAS1 EPAS1 GATA4 GATA4 GGNBP2 GGNBP2 MAP3K4 MAP3K4 PCDH12 PCDH12 WDR77 WDR77 PTGS2 PTGS2 LHX4 LHX4 NKX3-1 NKX3-1 FST FST PRDX4 PRDX4 ENSTTRP00000011747 ENSTTRP00000011747 PDGFRA PDGFRA DLG1 DLG1 ZFX ZFX EIF2B4 EIF2B4 FRS2 FRS2 HIF1A HIF1A VDR VDR SRD5A2 SRD5A2 ZFP42 ZFP42 WT1 WT1 PRDM1 PRDM1 KRT8 KRT8 PLK4 PLK4 CSMD1 CSMD1 ADA ADA LHX9 LHX9 ADAM19 ADAM19 TEX19 TEX19 GHSR GHSR GREB1 GREB1 VASH1 VASH1 NR0B1 NR0B1 ASH1L ASH1L GATA6 GATA6 SERPINE2 SERPINE2 LGR4 LGR4 ARID4A ARID4A SAFB2 SAFB2 CITED2 CITED2 TGFBR1 TGFBR1 SHH SHH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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HOXD13Homeobox protein Hox-D13. (321 aa)
RXFP2Relaxin receptor 2 isoform X1. (752 aa)
SIX4Homeobox protein SIX4. (494 aa)
VASH2Vasohibin 2. (311 aa)
BPTFNucleosome-remodeling factor subunit BPTF isoform X12. (2907 aa)
MSH4mutS protein homolog 4. (909 aa)
DMRT1Doublesex- and mab-3-related transcription factor 1. (374 aa)
WDR19WD repeat-containing protein 19 isoform X1. (1335 aa)
DAZAP1DAZ associated protein 1. (397 aa)
GRB2Growth factor receptor-bound protein 2. (156 aa)
CYP27C1Cytochrome P450 27C1 isoform X1. (372 aa)
PTX3Pentraxin 3. (381 aa)
KRT19Keratin 19. (400 aa)
DLG2Disks large homolog 2 isoform X2. (966 aa)
CCDC134Coiled-coil domain-containing protein 134 isoform X3. (154 aa)
DHCR24Delta(24)-sterol reductase isoform X1. (516 aa)
FGF8Fibroblast growth factor 8; Belongs to the heparin-binding growth factors family. (221 aa)
STK11Serine/threonine-protein kinase STK11 isoform X3. (340 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (173 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (854 aa)
SALL1Spalt like transcription factor 1. (1316 aa)
HS6ST1Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (247 aa)
DMRTA1Doublesex- and mab-3-related transcription factor A1. (498 aa)
PKD2Polycystin-2 isoform X2. (975 aa)
GCM1Chorion-specific transcription factor GCMa. (434 aa)
TMF1TATA element modulatory factor. (1091 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (953 aa)
LHX8LIM/homeobox protein Lhx8. (354 aa)
IGF2Insulin-like growth factor II. (184 aa)
ZNF830Zinc finger protein 830. (371 aa)
PKD1Polycystin-1 isoform X3. (4289 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
SPO11Meiotic recombination protein SPO11 isoform X1. (406 aa)
NUP107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (914 aa)
SETD2Histone-lysine N-methyltransferase SETD2. (2054 aa)
LOC101329540Histone H3; Belongs to the histone H3 family. (136 aa)
BMP6Bone morphogenetic protein 6. (304 aa)
GAS2Growth arrest-specific protein 2 isoform X4. (283 aa)
FEM1BProtein fem-1 homolog B isoform X1. (625 aa)
NIPBLNipped-B protein. (2801 aa)
SCAPERS phase cyclin A-associated protein in the endoplasmic reticulum isoform X2. (1367 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (616 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (336 aa)
MDFImyoD family inhibitor isoform X2. (246 aa)
MERTKTyrosine-protein kinase Mer. (999 aa)
EGLN1Egl nine homolog 1 isoform X1. (378 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa)
PLAG1Zinc finger protein PLAG1 isoform X1. (499 aa)
GPR149Probable G-protein coupled receptor 149. (734 aa)
RARARetinoic acid receptor alpha-like. (618 aa)
FOSL1Fos-related antigen 1. (271 aa)
SP3Transcription factor Sp3. (781 aa)
FOXO3Forkhead box protein O3. (612 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
ASB1Ankyrin repeat and SOCS box protein 1. (333 aa)
E2F7Transcription factor E2F7. (904 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa)
TPPP3Tubulin polymerization promoting protein family member 3. (176 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
SOCS3Suppressor of cytokine signaling 3. (229 aa)
ENSTTRP00000000710annotation not available (306 aa)
KDM5BLysine-specific demethylase 5B isoform X1. (1631 aa)
SFRP1Secreted frizzled-related protein 1 isoform X2. (307 aa)
NSDHLSterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family. (371 aa)
RBM15Putative RNA-binding protein 15. (975 aa)
CYR61Protein CYR61. (382 aa)
TNFAIP6Tumor necrosis factor-inducible gene 6 protein isoform X2. (277 aa)
LIFLeukemia inhibitory factor. (202 aa)
LEPLeptin. (167 aa)
HES1Transcription factor HES-1. (280 aa)
HSD17B3Testosterone 17-beta-dehydrogenase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa)
BIRC6LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 6. (4817 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (509 aa)
COL9A3Collagen alpha-3(IX) chain. (683 aa)
NHLH1Helix-loop-helix protein 1. (133 aa)
EIF2B2Translation initiation factor eIF-2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (316 aa)
TRIM28Transcription intermediary factor 1-beta. (720 aa)
SPATA2Spermatogenesis-associated protein 2. (520 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
ETV2ETS translocation variant 2. (362 aa)
CSMD2LOW QUALITY PROTEIN: CUB and sushi domain-containing protein 2-like. (3632 aa)
IMMP2LMitochondrial inner membrane protease subunit. (176 aa)
KDRVascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1307 aa)
HAND1Heart- and neural crest derivatives-expressed protein 1. (218 aa)
RARGRetinoic acid receptor beta. (453 aa)
TYRO3TYRO3 protein tyrosine kinase. (869 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (442 aa)
MYOCDMyocardin isoform X1. (968 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
EIF2B5Translation initiation factor eIF-2B subunit epsilon. (726 aa)
TIPARPTCDD-inducible poly [ADP-ribose] polymerase isoform X2. (657 aa)
NHLH2Helix-loop-helix protein 2. (135 aa)
NODALNodal homolog. (348 aa)
TBX3T-box transcription factor TBX3. (742 aa)
ENSTTRP00000003065annotation not available (386 aa)
ENSTTRP00000003132annotation not available (134 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (642 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (695 aa)
ZFP36L1mRNA decay activator protein ZFP36L1. (338 aa)
HOXA11Homeobox protein Hox-A11. (311 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
INHBAInhibin beta A chain. (421 aa)
WNT9BWnt family member 9B. (330 aa)
ZFATLOW QUALITY PROTEIN: zinc finger protein ZFAT. (1237 aa)
HECTD1E3 ubiquitin-protein ligase HECTD1 isoform X1. (2600 aa)
RSPO3R-spondin-3. (293 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
STRA6Stimulated by retinoic acid gene 6 protein homolog. (664 aa)
SLIT3Slit homolog 3 protein. (1521 aa)
ARAndrogen receptor. (886 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (931 aa)
CHD7chromodomain-helicase-DNA-binding protein 7 isoform X3. (2970 aa)
ATRXTranscriptional regulator ATRX isoform X3. (2518 aa)
FANCAFanconi anemia group A protein isoform X1. (1445 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
BRIP1Fanconi anemia group J protein isoform X1. (1232 aa)
GATA1Erythroid transcription factor. (383 aa)
VGFVGF nerve growth factor inducible. (616 aa)
DHHDesert hedgehog protein. (396 aa)
ATN1Atrophin 1. (1185 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type 6. (620 aa)
GREB1LGREB1-like protein. (871 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
TBC1D20TBC1 domain family member 20. (379 aa)
SERPINB5Serpin B5; Belongs to the serpin family. (375 aa)
PLEKHA1Pleckstrin homology domain-containing family A member 1 isoform X1. (398 aa)
HTRA1Serine protease HTRA1. (322 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
PCYT1BCholine-phosphate cytidylyltransferase B. (369 aa)
TNCTenascin isoform X2. (2104 aa)
DMC1Meiotic recombination protein DMC1/LIM15 homolog; Belongs to the RecA family. (340 aa)
SOX9Transcription factor SOX-9. (509 aa)
SRCProto-oncogene tyrosine-protein kinase Src. (538 aa)
E2F8Transcription factor E2F8 isoform X1. (866 aa)
SLIT2Slit homolog 2 protein isoform X2. (1470 aa)
FOXF2Forkhead box protein F1. (288 aa)
GRHL2Grainyhead-like protein 2 homolog isoform X4. (619 aa)
SOX8Transcription factor SOX-8. (445 aa)
TFAP2CUncharacterized protein LOC101321868. (450 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (853 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3043 aa)
BCL2L11Bcl-2-like protein 11 isoform X1. (196 aa)
CTNNB1Catenin beta-1. (781 aa)
WDR48WD repeat-containing protein 48 isoform X2. (677 aa)
TIFABTRAF-interacting protein with FHA domain-containing protein B. (162 aa)
CITED1Cbp/p300-interacting transactivator 1 isoform X1. (191 aa)
NRIP1Nuclear receptor-interacting protein 1. (819 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
PLCD3Phosphoinositide phospholipase C. (782 aa)
STK3Serine/threonine-protein kinase 3 isoform X1. (480 aa)
FANCGFanconi anemia group G protein isoform X1. (585 aa)
RTCBRNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. (470 aa)
SCXScleraxis bHLH transcription factor. (203 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4599 aa)
AFPAlpha-fetoprotein. (610 aa)
EIF2S2Eukaryotic translation initiation factor 2 subunit 2. (322 aa)
KLHL10LOW QUALITY PROTEIN: kelch-like protein 10. (608 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
HSD17B2Estradiol 17-beta-dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (386 aa)
SERPINF1Pigment epithelium-derived factor; Belongs to the serpin family. (416 aa)
HYAL3Hyaluronidase. (459 aa)
BAK1BCL2 antagonist/killer 1. (212 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
CUL7Cullin-7; Belongs to the cullin family. (1691 aa)
AXLTyrosine-protein kinase receptor UFO. (870 aa)
LRRC6Protein tilB homolog. (473 aa)
STAT5ASignal transducer and activator of transcription 5A. (794 aa)
HOXB13Homeobox B13. (285 aa)
BIKBcl-2-interacting killer isoform X2. (143 aa)
ARNTAryl hydrocarbon receptor nuclear translocator isoform X3. (845 aa)
GHRLAppetite-regulating hormone. (117 aa)
LHX3LIM/homeobox protein Lhx3. (403 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (406 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2527 aa)
STK4Serine/threonine-protein kinase 4 isoform X1. (435 aa)
ADAMTS1A disintegrin and metalloproteinase with thrombospondin motifs 1. (956 aa)
YBX3Y-box-binding protein 3 isoform X1. (264 aa)
LEF1Lymphoid enhancer binding factor 1. (396 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (315 aa)
CYP27B125-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial isoform X2; Belongs to the cytochrome P450 family. (508 aa)
HNF1AHNF1 homeobox A. (632 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1512 aa)
REC8Meiotic recombination protein REC8 homolog. (546 aa)
PTNPleiotrophin isoform X1. (249 aa)
BCL2L2Bcl-2-like protein 2. (193 aa)
ETNK2Ethanolamine kinase 2. (393 aa)
RENRenin isoform X1; Belongs to the peptidase A1 family. (407 aa)
SF1Splicing factor 1. (526 aa)
LHX1LIM/homeobox protein Lhx1. (406 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
HESX1Homeobox expressed in ES cells 1 isoform X1. (132 aa)
CRKLCrk-like protein. (303 aa)
TAF4Transcription initiation factor TFIID subunit 4 isoform X1. (709 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
LOC101336078Schwannomin-interacting protein 1 isoform X1. (484 aa)
ALKBH1alkB homolog 1, histone H2A dioxygenase. (387 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
STOX2Storkhead-box protein 2 isoform X2. (949 aa)
PPARDPeroxisome proliferator-activated receptor delta. (441 aa)
ENSTTRP00000008984annotation not available (113 aa)
NKX2-1Homeobox protein Nkx-2.1. (394 aa)
ING2Inhibitor of growth protein. (222 aa)
TCF21Transcription factor 21. (162 aa)
PHLDA2Pleckstrin homology-like domain family A member 2. (131 aa)
SPINT2LOW QUALITY PROTEIN: kunitz-type protease inhibitor 2-like. (249 aa)
ENSTTRP00000009296annotation not available (181 aa)
LOC101318745Histone H3.3-like. (136 aa)
OSR1Protein odd-skipped-related 1. (267 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
ARID5BAT-rich interactive domain-containing protein 5B isoform X1. (1176 aa)
PTPRNProtein tyrosine phosphatase receptor type N. (980 aa)
ANXA1Annexin. (328 aa)
ADGRG1Adhesion G-protein coupled receptor G1. (691 aa)
ENSTTRP00000009655annotation not available (318 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (393 aa)
SOX15Transcription factor SOX-1. (175 aa)
PATZ1POZ-, AT hook-, and zinc finger-containing protein 1. (687 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
FGF10Fibroblast growth factor 10. (142 aa)
KIF18AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (891 aa)
ST14Suppression of tumorigenicity 14. (627 aa)
BRCA2Breast cancer type 2 susceptibility protein. (3307 aa)
FBXW8F-box/WD repeat-containing protein 8. (599 aa)
CDX4Homeobox protein CDX-4. (282 aa)
PRDX3Thioredoxin-dependent peroxide reductase, mitochondrial isoform X1. (257 aa)
GFRA1GDNF family receptor alpha; Belongs to the GDNFR family. (463 aa)
RAB13Ras-related protein Rab-13. (203 aa)
SYCP2Synaptonemal complex protein 2. (1501 aa)
SPINT1Kunitz-type protease inhibitor 1. (500 aa)
EAF2ELL-associated factor 2. (263 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
SMAD4Mothers against decapentaplegic homolog. (407 aa)
EPAS1Endothelial PAS domain protein 1. (870 aa)
GATA4Transcription factor GATA-4 isoform X2. (442 aa)
GGNBP2Gametogenetin-binding protein 2 isoform X6. (696 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4 isoform X1. (1594 aa)
PCDH12Protocadherin-12. (1183 aa)
WDR77Methylosome protein 50 isoform X1. (341 aa)
PTGS2Prostaglandin G/H synthase 2. (603 aa)
LHX4LIM/homeobox protein Lhx4. (390 aa)
NKX3-1Homeobox protein Nkx-3.1. (138 aa)
FSTFollistatin isoform X2. (343 aa)
PRDX4Peroxiredoxin-4. (271 aa)
ENSTTRP00000011747annotation not available (136 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1040 aa)
DLG1Disks large homolog 1 isoform X3; Belongs to the MAGUK family. (920 aa)
ZFXZinc finger X-chromosomal protein isoform X1. (800 aa)
EIF2B4Eukaryotic translation initiation factor 2B subunit delta. (524 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (824 aa)
VDRVitamin D3 receptor. (427 aa)
SRD5A23-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). (254 aa)
ZFP42Zinc finger protein 42 homolog. (304 aa)
WT1Wilms tumor protein isoform X2. (336 aa)
PRDM1PR domain zinc finger protein 1 isoform X1. (787 aa)
KRT8LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8-like; Belongs to the intermediate filament family. (483 aa)
PLK4Serine/threonine-protein kinase PLK4 isoform X2. (973 aa)
CSMD1CUB and sushi domain-containing protein 1. (3040 aa)
ADAAdenosine deaminase isoform X3. (406 aa)
LHX9LIM/homeobox protein Lhx9 isoform X3. (285 aa)
ADAM19Disintegrin and metalloproteinase domain-containing protein 19. (909 aa)
TEX19Testis-expressed sequence 19 protein. (166 aa)
GHSRGrowth hormone secretagogue receptor type 1; Belongs to the G-protein coupled receptor 1 family. (365 aa)
GREB1Growth regulating estrogen receptor binding 1. (1943 aa)
VASH1Vasohibin-1. (363 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (464 aa)
ASH1LHistone-lysine N-methyltransferase ASH1L isoform X1. (2967 aa)
GATA6Transcription factor GATA-6. (592 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (398 aa)
LGR4Leucine-rich repeat-containing G-protein coupled receptor 4 isoform X1. (908 aa)
ARID4AAT-rich interactive domain-containing protein 4A isoform X2. (1258 aa)
SAFB2Scaffold attachment factor B2 isoform X1. (947 aa)
CITED2Cbp/p300-interacting transactivator 2. (272 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (458 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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