STRINGSTRING
UBE3A UBE3A TBX3 TBX3 LAMA1 LAMA1 NODAL NODAL SMAD3 SMAD3 NRG3 NRG3 ESR1 ESR1 TYR TYR MSN MSN FOXA1 FOXA1 PDX1 PDX1 RARG RARG MST1 MST1 OTP OTP SLC9A3R1 SLC9A3R1 BMP2 BMP2 FRZB FRZB BRAF BRAF EDNRA EDNRA PAX1 PAX1 PAX6 PAX6 IGSF3 IGSF3 PLXNA1 PLXNA1 ACER1 ACER1 RELA RELA CSMD2 CSMD2 NKX2-3 NKX2-3 SELENOH SELENOH DNAAF1 DNAAF1 SMARCB1 SMARCB1 GHRH GHRH ENSTTRP00000001685 ENSTTRP00000001685 HES1 HES1 HAND2 HAND2 EDA EDA IRF6 IRF6 IQGAP3 IQGAP3 SFRP1 SFRP1 KDM5B KDM5B C6orf58 C6orf58 SRP54 SRP54 LRRC1 LRRC1 PCK1 PCK1 ZBTB1 ZBTB1 CCDC40 CCDC40 ATF2 ATF2 FA2H FA2H GHRHR GHRHR NOTCH2 NOTCH2 CUL3 CUL3 CADM1 CADM1 HGF HGF E2F7 E2F7 PML PML SULF2 SULF2 NR5A1 NR5A1 EPHA2 EPHA2 EZH2 EZH2 CCND1 CCND1 SCRIB SCRIB SP3 SP3 ZNF703 ZNF703 PITX1 PITX1 PLAG1 PLAG1 TGM2 TGM2 MAPK1 MAPK1 NTN1 NTN1 CDK5RAP3 CDK5RAP3 LRP5 LRP5 UPF2 UPF2 RXFP1 RXFP1 ASCL1 ASCL1 PRL PRL PYGO2 PYGO2 ZBTB7B ZBTB7B ENSTTRP00000015206 ENSTTRP00000015206 FEM1B FEM1B HNF1B HNF1B CREB1 CREB1 BMP7 BMP7 PKD1 PKD1 CACNB4 CACNB4 PCSK9 PCSK9 NPHP3 NPHP3 NF1 NF1 PROP1 PROP1 MAN2A1 MAN2A1 TGFB3 TGFB3 PKD2 PKD2 ABL1 ABL1 SALL1 SALL1 CDKN1B CDKN1B STK11 STK11 FGF8 FGF8 BTRC BTRC TWSG1 TWSG1 RB1CC1 RB1CC1 CCDC39 CCDC39 ESRP2 ESRP2 EXT1 EXT1 CCL11 CCL11 BAAT BAAT ORAI1 ORAI1 ACADM ACADM JARID2 JARID2 CSN3 CSN3 PIK3CA PIK3CA TPH1 TPH1 SIX4 SIX4 SIX1 SIX1 NOTCH4 NOTCH4 HOXD3 HOXD3 HOXD13 HOXD13 SHH SHH TGFBR1 TGFBR1 CITED2 CITED2 TGFB2 TGFB2 TNFRSF11A TNFRSF11A COBL COBL SERPINE2 SERPINE2 ONECUT1 ONECUT1 GATA6 GATA6 ASH1L ASH1L WNT11 WNT11 NR0B1 NR0B1 EPHB3 EPHB3 CSN2 CSN2 GLI1 GLI1 STAT6 STAT6 ADA ADA CSMD1 CSMD1 HNF4A HNF4A ONECUT2 ONECUT2 TGFB1 TGFB1 WT1 WT1 RPGRIP1L RPGRIP1L VDR VDR HIF1A HIF1A FRS2 FRS2 ARMC5 ARMC5 PDGFRA PDGFRA NKX3-1 NKX3-1 ATP2C2 ATP2C2 HOXB9 HOXB9 HOXB3 HOXB3 DDR1 DDR1 WDR77 WDR77 MSX1 MSX1 BCL11B BCL11B PAX8 PAX8 RHBDD3 RHBDD3 PTCD2 PTCD2 MAFB MAFB SMAD4 SMAD4 AREG AREG TP63 TP63 JUN JUN EAF2 EAF2 ARHGAP35 ARHGAP35 GFER GFER PLXND1 PLXND1 CLCN2 CLCN2 BSX BSX LAMA5 LAMA5 PTCH1 PTCH1 NFKB1 NFKB1 ISL1 ISL1 MAD1L1 MAD1L1 NFIB NFIB DKK3 DKK3 ENSTTRP00000009881 ENSTTRP00000009881 FGF10 FGF10 WNT2 WNT2 CTC1 CTC1 MAP2K1 MAP2K1 TNFSF11 TNFSF11 ERBB4 ERBB4 ANXA1 ANXA1 ELK1 ELK1 WNT10A WNT10A ARID5B ARID5B SOSTDC1 SOSTDC1 ENSTTRP00000009296 ENSTTRP00000009296 POLB POLB TCF21 TCF21 NKX2-1 NKX2-1 FASN FASN LSR LSR SLC46A2 SLC46A2 PSEN1 PSEN1 BMP4 BMP4 CRKL CRKL HESX1 HESX1 ENSTTRP00000008594 ENSTTRP00000008594 IL6 IL6 SEC63 SEC63 SEMA3C SEMA3C FGF7 FGF7 ID2 ID2 RIPK3 RIPK3 PCK2 PCK2 CAV1 CAV1 MED1 MED1 SMO SMO HNF1A HNF1A AGAP2 AGAP2 ENSTTRP00000007731 ENSTTRP00000007731 BMPR1A BMPR1A LEF1 LEF1 ZDHHC21 ZDHHC21 ASXL1 ASXL1 NOTCH1 NOTCH1 LHX3 LHX3 ZNF330 ZNF330 EDAR EDAR DRD2 DRD2 HOXB13 HOXB13 DDX55 DDX55 STAT5A STAT5A SRF SRF TGFA TGFA SERPINF1 SERPINF1 HOXA5 HOXA5 HOXA3 HOXA3 ENSTTRP00000006381 ENSTTRP00000006381 STAT5B STAT5B CTNNB1 CTNNB1 BCL2L11 BCL2L11 EDN1 EDN1 ATM ATM LATS1 LATS1 ELF3 ELF3 ZMPSTE24 ZMPSTE24 FOXF1 FOXF1 E2F8 E2F8 SRC SRC GSX1 GSX1 SOX9 SOX9 TNC TNC MAPK3 MAPK3 WNT5A WNT5A SERPINB5 SERPINB5 ALDH1A3 ALDH1A3 BCL2 BCL2 GATA3 GATA3 TAF10 TAF10 SOX10 SOX10 PHB2 PHB2 EGF EGF TBX2 TBX2 NKX2-5 NKX2-5 AR AR STRA6 STRA6 FOXN1 FOXN1 CEBPB CEBPB WNT3 WNT3 GCM2 GCM2 GLI3 GLI3 SLC6A3 SLC6A3 GPAT4 GPAT4 FGL1 FGL1 ZIC3 ZIC3 PROX1 PROX1 TFCP2L1 TFCP2L1 NEURL1 NEURL1 ENSTTRP00000003132 ENSTTRP00000003132 SOCS2 SOCS2
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (853 aa)
TBX3T-box transcription factor TBX3. (742 aa)
LAMA1Laminin subunit alpha-1. (3051 aa)
NODALNodal homolog. (348 aa)
SMAD3Mothers against decapentaplegic homolog 3. (291 aa)
NRG3Pro-neuregulin-3, membrane-bound isoform. (724 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
TYRTyrosinase. (530 aa)
MSNMoesin. (576 aa)
FOXA1Hepatocyte nuclear factor 3-alpha. (442 aa)
PDX1Pancreas/duodenum homeobox protein 1. (283 aa)
RARGRetinoic acid receptor beta. (453 aa)
MST1Hepatocyte growth factor-like protein isoform X1; Belongs to the peptidase S1 family. Plasminogen subfamily. (709 aa)
OTPHomeobox protein orthopedia. (325 aa)
SLC9A3R1SLC9A3 regulator 1. (359 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X4. (757 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PAX1Paired box protein Pax-1. (422 aa)
PAX6Paired box protein Pax-6. (436 aa)
IGSF3Immunoglobulin superfamily member 3. (1099 aa)
PLXNA1plexin-A1. (1889 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
RELARELA proto-oncogene, NF-kB subunit. (574 aa)
CSMD2LOW QUALITY PROTEIN: CUB and sushi domain-containing protein 2-like. (3632 aa)
NKX2-3Homeobox protein Nkx-2.3. (365 aa)
SELENOHSelenoprotein H isoform X2. (118 aa)
DNAAF1Dynein assembly factor 1, axonemal. (647 aa)
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1. (387 aa)
GHRHSomatoliberin isoform X2. (107 aa)
ENSTTRP00000001685annotation not available (391 aa)
HES1Transcription factor HES-1. (280 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (208 aa)
EDAectodysplasin-A isoform X1. (391 aa)
IRF6Interferon regulatory factor 6 isoform X2. (467 aa)
IQGAP3Ras GTPase-activating-like protein IQGAP3 isoform X1. (1636 aa)
SFRP1Secreted frizzled-related protein 1 isoform X2. (307 aa)
KDM5BLysine-specific demethylase 5B isoform X1. (1631 aa)
C6orf58Protein LEG1 homolog. (327 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
LRRC1Leucine-rich repeat-containing protein 1 isoform X1. (522 aa)
PCK1Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa)
ZBTB1Zinc finger and BTB domain-containing protein 1. (713 aa)
CCDC40Coiled-coil domain-containing protein 40. (1124 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
FA2HFatty acid 2-hydroxylase; Belongs to the cytochrome b5 family. (372 aa)
GHRHRGrowth hormone-releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (420 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa)
CUL3Cullin-3 isoform X1; Belongs to the cullin family. (745 aa)
CADM1Cell adhesion molecule 1 isoform X2. (445 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (727 aa)
E2F7Transcription factor E2F7. (904 aa)
PMLProtein PML isoform X2. (871 aa)
SULF2Sulfatase 2. (847 aa)
NR5A1Nuclear receptor subfamily 5 group A member 1. (461 aa)
EPHA2Ephrin type-A receptor 2-like. (974 aa)
EZH2Histone-lysine N-methyltransferase EZH2 isoform X2. (751 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
SCRIBProtein scribble homolog. (1596 aa)
SP3Transcription factor Sp3. (781 aa)
ZNF703Zinc finger protein 703. (585 aa)
PITX1Homeobox protein. (314 aa)
PLAG1Zinc finger protein PLAG1 isoform X1. (499 aa)
TGM2Protein-glutamine gamma-glutamyltransferase 2. (717 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa)
NTN1Netrin-1. (604 aa)
CDK5RAP3CDK5 regulatory subunit-associated protein 3 isoform X1. (505 aa)
LRP5LOW QUALITY PROTEIN: low-density lipoprotein receptor-related protein 5. (1582 aa)
UPF2Regulator of nonsense transcripts 2 isoform X2. (1270 aa)
RXFP1Relaxin receptor 1. (757 aa)
ASCL1Achaete-scute homolog 1. (172 aa)
PRLProlactin isoform X1. (230 aa)
PYGO2Pygopus family PHD finger 2. (406 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (416 aa)
ENSTTRP00000015206annotation not available (554 aa)
FEM1BProtein fem-1 homolog B isoform X1. (625 aa)
HNF1BHepatocyte nuclear factor 1-beta isoform X2. (436 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
PKD1Polycystin-1 isoform X3. (4289 aa)
CACNB4Voltage-dependent L-type calcium channel subunit beta-4. (520 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (692 aa)
NPHP3Nephrocystin-3 isoform X1. (1356 aa)
NF1Neurofibromin. (2814 aa)
PROP1Homeobox protein prophet of Pit-1. (226 aa)
MAN2A1Alpha-mannosidase. (1134 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
PKD2Polycystin-2 isoform X2. (975 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
SALL1Spalt like transcription factor 1. (1316 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (173 aa)
STK11Serine/threonine-protein kinase STK11 isoform X3. (340 aa)
FGF8Fibroblast growth factor 8; Belongs to the heparin-binding growth factors family. (221 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (605 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
RB1CC1RB1-inducible coiled-coil protein 1 isoform X4. (1518 aa)
CCDC39Coiled-coil domain-containing protein 39. (732 aa)
ESRP2Epithelial splicing regulatory protein 2. (717 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
CCL11C-C motif chemokine. (97 aa)
BAATLOW QUALITY PROTEIN: bile acid-CoA:amino acid N-acyltransferase-like. (419 aa)
ORAI1Calcium release-activated calcium channel protein 1. (238 aa)
ACADMMedium-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1. (454 aa)
JARID2Protein Jumonji. (1235 aa)
CSN3Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk; Belongs to the kappa-casein family. (181 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1067 aa)
TPH1Tryptophan 5-hydroxylase 1. (465 aa)
SIX4Homeobox protein SIX4. (494 aa)
SIX1Homeobox protein SIX1. (284 aa)
NOTCH4Neurogenic locus notch homolog protein 4. (1982 aa)
HOXD3Homeobox protein Hox-D3. (432 aa)
HOXD13Homeobox protein Hox-D13. (321 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (458 aa)
CITED2Cbp/p300-interacting transactivator 2. (272 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
TNFRSF11ATumor necrosis factor receptor superfamily member 11A isoform X2. (562 aa)
COBLProtein cordon-bleu isoform X4. (1337 aa)
SERPINE2Glia-derived nexin; Belongs to the serpin family. (398 aa)
ONECUT1One cut homeobox 1. (465 aa)
GATA6Transcription factor GATA-6. (592 aa)
ASH1LHistone-lysine N-methyltransferase ASH1L isoform X1. (2967 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (464 aa)
EPHB3EPH receptor B3. (994 aa)
CSN2Beta-casein. (216 aa)
GLI1Zinc finger protein GLI1. (1106 aa)
STAT6Signal transducer and activator of transcription 6. (847 aa)
ADAAdenosine deaminase isoform X3. (406 aa)
CSMD1CUB and sushi domain-containing protein 1. (3040 aa)
HNF4AHepatocyte nuclear factor 4-alpha isoform X1. (448 aa)
ONECUT2One cut domain family member 2. (419 aa)
TGFB1Transforming growth factor beta 1. (338 aa)
WT1Wilms tumor protein isoform X2. (336 aa)
RPGRIP1LProtein fantom. (1255 aa)
VDRVitamin D3 receptor. (427 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (824 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
ARMC5Armadillo repeat-containing protein 5-like. (777 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1040 aa)
NKX3-1Homeobox protein Nkx-3.1. (138 aa)
ATP2C2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (937 aa)
HOXB9Homeobox protein Hox-B9. (250 aa)
HOXB3Homeobox protein Hox-B3. (424 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (915 aa)
WDR77Methylosome protein 50 isoform X1. (341 aa)
MSX1Homeobox protein MSX-1. (303 aa)
BCL11BB-cell lymphoma/leukemia 11B. (897 aa)
PAX8Paired box protein Pax-8. (445 aa)
RHBDD3Rhomboid domain-containing protein 3. (385 aa)
PTCD2Pentatricopeptide repeat-containing protein 2, mitochondrial. (388 aa)
MAFBTranscription factor MafB. (323 aa)
SMAD4Mothers against decapentaplegic homolog. (407 aa)
AREGAmphiregulin isoform X2. (253 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (321 aa)
EAF2ELL-associated factor 2. (263 aa)
ARHGAP35Rho GTPase-activating protein 35 isoform X1. (1510 aa)
GFERGrowth factor, augmenter of liver regeneration. (206 aa)
PLXND1plexin-D1. (1687 aa)
CLCN2Chloride voltage-gated channel 2. (901 aa)
BSXBrain-specific homeobox protein homolog. (197 aa)
LAMA5Laminin subunit alpha-5-like. (3506 aa)
PTCH1Protein patched homolog 1 isoform X1. (1313 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
MAD1L1Mitotic spindle assembly checkpoint protein MAD1 isoform X1. (755 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
DKK3Dickkopf-related protein 3. (282 aa)
ENSTTRP00000009881annotation not available (525 aa)
FGF10Fibroblast growth factor 10. (142 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
CTC1CST complex subunit CTC1. (1156 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (393 aa)
TNFSF11Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family. (318 aa)
ERBB4Receptor protein-tyrosine kinase. (1299 aa)
ANXA1Annexin. (328 aa)
ELK1ETS domain-containing protein Elk-1 isoform X2. (469 aa)
WNT10AWnt family member 10A. (417 aa)
ARID5BAT-rich interactive domain-containing protein 5B isoform X1. (1176 aa)
SOSTDC1Sclerostin domain-containing protein 1. (229 aa)
ENSTTRP00000009296annotation not available (181 aa)
POLBDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (335 aa)
TCF21Transcription factor 21. (162 aa)
NKX2-1Homeobox protein Nkx-2.1. (394 aa)
FASNFatty acid synthase. (2087 aa)
LSRLipolysis stimulated lipoprotein receptor. (558 aa)
SLC46A2Thymic stromal cotransporter homolog. (362 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (466 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
CRKLCrk-like protein. (303 aa)
HESX1Homeobox expressed in ES cells 1 isoform X1. (132 aa)
ENSTTRP00000008594annotation not available (430 aa)
IL6Interleukin-6. (208 aa)
SEC63Translocation protein SEC63 homolog. (759 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
RIPK3Receptor interacting serine/threonine kinase 3. (502 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (560 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (134 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1512 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
HNF1AHNF1 homeobox A. (632 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1190 aa)
ENSTTRP00000007731annotation not available (287 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
LEF1Lymphoid enhancer binding factor 1. (396 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
ASXL1Putative Polycomb group protein ASXL1 isoform X1. (1526 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2527 aa)
LHX3LIM/homeobox protein Lhx3. (403 aa)
ZNF330Zinc finger protein 330 isoform X1. (320 aa)
EDARTumor necrosis factor receptor superfamily member EDAR. (473 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (445 aa)
HOXB13Homeobox B13. (285 aa)
DDX55RNA helicase. (600 aa)
STAT5ASignal transducer and activator of transcription 5A. (794 aa)
SRFSerum response factor isoform X2. (509 aa)
TGFAProtransforming growth factor alpha isoform X1. (224 aa)
SERPINF1Pigment epithelium-derived factor; Belongs to the serpin family. (416 aa)
HOXA5Homeobox A5. (268 aa)
HOXA3Homeobox protein Hox-A3. (432 aa)
ENSTTRP00000006381annotation not available (382 aa)
STAT5BSignal transducer and activator of transcription. (787 aa)
CTNNB1Catenin beta-1. (781 aa)
BCL2L11Bcl-2-like protein 11 isoform X1. (196 aa)
EDN1Endothelin-1. (202 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3043 aa)
LATS1Serine/threonine-protein kinase LATS1. (958 aa)
ELF3ETS-related transcription factor Elf-3. (340 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)
FOXF1Forkhead box F1. (372 aa)
E2F8Transcription factor E2F8 isoform X1. (866 aa)
SRCProto-oncogene tyrosine-protein kinase Src. (538 aa)
GSX1GS homeobox 1. (233 aa)
SOX9Transcription factor SOX-9. (509 aa)
TNCTenascin isoform X2. (2104 aa)
MAPK3Mitogen-activated protein kinase 3. (382 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
SERPINB5Serpin B5; Belongs to the serpin family. (375 aa)
ALDH1A3Aldehyde dehydrogenase family 1 member A3 isoform X1; Belongs to the aldehyde dehydrogenase family. (478 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
SOX10Transcription factor SOX-10. (468 aa)
PHB2Prohibitin 2. (298 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1205 aa)
TBX2T-box transcription factor TBX2. (703 aa)
NKX2-5Homeobox protein Nkx-2.5. (323 aa)
ARAndrogen receptor. (886 aa)
STRA6Stimulated by retinoic acid gene 6 protein homolog. (664 aa)
FOXN1Forkhead box protein N1 isoform X1. (645 aa)
CEBPBCCAAT/enhancer-binding protein. (345 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
GCM2Chorion-specific transcription factor GCMb. (507 aa)
GLI3Transcriptional activator GLI3. (1580 aa)
SLC6A3Solute carrier family 6 member 3. (617 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4 isoform X1. (454 aa)
FGL1Fibrinogen-like protein 1 isoform X1. (312 aa)
ZIC3Zinc finger protein ZIC 3 isoform X1. (462 aa)
PROX1Prospero homeobox protein 1. (744 aa)
TFCP2L1Transcription factor CP2-like protein 1. (472 aa)
NEURL1E3 ubiquitin-protein ligase NEURL1. (574 aa)
ENSTTRP00000003132annotation not available (134 aa)
SOCS2Suppressor of cytokine signaling 2. (198 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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