STRINGSTRING
SEMA3G SEMA3G ANXA6 ANXA6 SFRP1 SFRP1 SIX2 SIX2 SEMA3A SEMA3A AMER1 AMER1 HAND2 HAND2 SEMA4A SEMA4A EDNRB EDNRB FAM172A FAM172A RET RET EPB41L5 EPB41L5 HES1 HES1 SEMA6B SEMA6B PHACTR4 PHACTR4 TRIM28 TRIM28 SNAI1 SNAI1 GDNF GDNF ALDH1A2 ALDH1A2 EDNRA EDNRA FRZB FRZB BMP2 BMP2 HMGA2 HMGA2 RFLNB RFLNB TASOR TASOR TBX3 TBX3 HAS2 HAS2 SEMA4D SEMA4D WWTR1 WWTR1 PHOX2B PHOX2B MEF2C MEF2C CORO1C CORO1C FGFR1 FGFR1 RTN4 RTN4 OTUD5 OTUD5 SOX10 SOX10 SEMA6A SEMA6A SEMA5A SEMA5A BCL2 BCL2 SEMA3E SEMA3E WNT5A WNT5A AKNA AKNA MAPK3 MAPK3 DDX17 DDX17 SOX9 SOX9 AMELX AMELX SOX8 SOX8 EFNB1 EFNB1 EDN1 EDN1 JAG1 JAG1 KLHL12 KLHL12 CUL7 CUL7 SEMA6C SEMA6C CDH2 CDH2 GBX2 GBX2 NOTCH1 NOTCH1 FAM83D FAM83D SEMA3F SEMA3F SEMA3B SEMA3B ACVR1 ACVR1 DLG5 DLG5 SEMA4C SEMA4C GSC GSC SEMA7A SEMA7A LEF1 LEF1 BMPR1A BMPR1A RANBP3L RANBP3L SMO SMO SEMA3C SEMA3C DDX5 DDX5 RDH10 RDH10 BMP4 BMP4 NRTN NRTN SEMA3D SEMA3D TCF21 TCF21 ENSTTRP00000009296 ENSTTRP00000009296 OSR1 OSR1 NRP1 NRP1 WNT10A WNT10A ERBB4 ERBB4 WNT2 WNT2 FGF10 FGF10 FOLR1 FOLR1 ISL1 ISL1 LAMA5 LAMA5 TMEM100 TMEM100 SEMA5B SEMA5B SMAD4 SMAD4 RADIL RADIL KBTBD8 KBTBD8 MSX1 MSX1 LOXL2 LOXL2 CYP26C1 CYP26C1 HIF1A HIF1A LOXL3 LOXL3 SEMA4F SEMA4F LRP6 LRP6 TGFB1 TGFB1 TCOF1 TCOF1 PEF1 PEF1 WNT11 WNT11 TGFB2 TGFB2 CITED2 CITED2 TGFBR1 TGFBR1 SHH SHH NOTCH4 NOTCH4 SIX1 SIX1 FLNA FLNA TGFBR3 TGFBR3 HEYL HEYL EXT1 EXT1 ALX1 ALX1 NRP2 NRP2 FGF8 FGF8 NOLC1 NOLC1 SEMA4G SEMA4G ROCK1 ROCK1 BMP7 BMP7 SEMA6D SEMA6D SEMA4B SEMA4B HTR2B HTR2B EFNA1 EFNA1 ADAM15 ADAM15 WNT16 WNT16 HEY2 HEY2 ENG ENG GSK3B GSK3B MAPK1 MAPK1 ENSTTRP00000016529 ENSTTRP00000016529 TBX20 TBX20
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEMA3GSemaphorin 3G. (765 aa)
ANXA6Annexin. (722 aa)
SFRP1Secreted frizzled-related protein 1 isoform X2. (307 aa)
SIX2Homeobox protein SIX2. (168 aa)
SEMA3Asemaphorin-3A; Belongs to the semaphorin family. (772 aa)
AMER1APC membrane recruitment protein 1. (1114 aa)
HAND2Heart- and neural crest derivatives-expressed protein 2. (208 aa)
SEMA4Asemaphorin-4A; Belongs to the semaphorin family. (762 aa)
EDNRBEndothelin B receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (530 aa)
FAM172AProtein FAM172A isoform X1. (416 aa)
RETRet proto-oncogene. (1113 aa)
EPB41L5Band 4.1-like protein 5 isoform X3. (728 aa)
HES1Transcription factor HES-1. (280 aa)
SEMA6Bsemaphorin-6B-like. (677 aa)
PHACTR4Phosphatase and actin regulator. (718 aa)
TRIM28Transcription intermediary factor 1-beta. (720 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
GDNFGlial cell line-derived neurotrophic factor isoform X2. (211 aa)
ALDH1A2Retinal dehydrogenase 2; Belongs to the aldehyde dehydrogenase family. (518 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
HMGA2High mobility group protein HMGI-C. (83 aa)
RFLNBFilamin-interacting protein FAM101B isoform X1. (146 aa)
TASORProtein TASOR isoform X3. (1229 aa)
TBX3T-box transcription factor TBX3. (742 aa)
HAS2Hyaluronan synthase 2. (552 aa)
SEMA4Dsemaphorin-4D isoform X1; Belongs to the semaphorin family. (863 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (234 aa)
MEF2CMyocyte-specific enhancer factor 2C isoform X1. (472 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (464 aa)
FGFR1Fibroblast growth factor receptor 1. (822 aa)
RTN4Reticulon. (1189 aa)
OTUD5OTU domain-containing protein 5 isoform X4. (568 aa)
SOX10Transcription factor SOX-10. (468 aa)
SEMA6Asemaphorin-6A isoform X1; Belongs to the semaphorin family. (1032 aa)
SEMA5Asemaphorin-5A. (1073 aa)
BCL2Apoptosis regulator Bcl-2 isoform X1. (233 aa)
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (775 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
AKNAAT-hook-containing transcription factor. (1460 aa)
MAPK3Mitogen-activated protein kinase 3. (382 aa)
DDX17Probable ATP-dependent RNA helicase DDX17 isoform X2; Belongs to the DEAD box helicase family. (632 aa)
SOX9Transcription factor SOX-9. (509 aa)
AMELXAmelogenin, X isoform. (183 aa)
SOX8Transcription factor SOX-8. (445 aa)
EFNB1Ephrin B1. (346 aa)
EDN1Endothelin-1. (202 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
KLHL12Kelch-like protein 12 isoform X4. (567 aa)
CUL7Cullin-7; Belongs to the cullin family. (1691 aa)
SEMA6CSemaphorin 6C. (966 aa)
CDH2Cadherin-2 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
GBX2Homeobox protein GBX-2 isoform X1. (348 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2527 aa)
FAM83DProtein FAM83D. (587 aa)
SEMA3FSemaphorin 3F. (784 aa)
SEMA3Bsemaphorin-3B; Belongs to the semaphorin family. (747 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (485 aa)
DLG5Disks large homolog 5; Belongs to the MAGUK family. (1816 aa)
SEMA4Csemaphorin-4C. (833 aa)
GSCHomeobox protein goosecoid. (256 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group). (663 aa)
LEF1Lymphoid enhancer binding factor 1. (396 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
RANBP3LRan-binding protein 3-like. (466 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
DDX5Probable ATP-dependent RNA helicase DDX5. (614 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
NRTNNeurturin. (197 aa)
SEMA3Dsemaphorin-3D; Belongs to the semaphorin family. (777 aa)
TCF21Transcription factor 21. (162 aa)
ENSTTRP00000009296annotation not available (181 aa)
OSR1Protein odd-skipped-related 1. (267 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
WNT10AWnt family member 10A. (417 aa)
ERBB4Receptor protein-tyrosine kinase. (1299 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
FGF10Fibroblast growth factor 10. (142 aa)
FOLR1Folate receptor gamma. (251 aa)
ISL1Insulin gene enhancer protein ISL-1. (349 aa)
LAMA5Laminin subunit alpha-5-like. (3506 aa)
TMEM100Transmembrane protein 100. (134 aa)
SEMA5BSemaphorin 5B. (1138 aa)
SMAD4Mothers against decapentaplegic homolog. (407 aa)
RADILRas-associating and dilute domain-containing protein-like. (1072 aa)
KBTBD8Kelch repeat and BTB domain-containing protein 8. (574 aa)
MSX1Homeobox protein MSX-1. (303 aa)
LOXL2Lysyl oxidase homolog 2. (771 aa)
CYP26C1Cytochrome P450 26C1; Belongs to the cytochrome P450 family. (398 aa)
HIF1AHypoxia-inducible factor 1-alpha isoform X1. (824 aa)
LOXL3Lysyl oxidase homolog 3 isoform X2. (752 aa)
SEMA4Fsemaphorin-4F isoform X1; Belongs to the semaphorin family. (773 aa)
LRP6Low-density lipoprotein receptor-related protein 6. (1611 aa)
TGFB1Transforming growth factor beta 1. (338 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1294 aa)
PEF1Peflin isoform X1. (290 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
CITED2Cbp/p300-interacting transactivator 2. (272 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (458 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
NOTCH4Neurogenic locus notch homolog protein 4. (1982 aa)
SIX1Homeobox protein SIX1. (284 aa)
FLNAfilamin-A-like. (2634 aa)
TGFBR3Transforming growth factor beta receptor type 3 isoform X4. (848 aa)
HEYLHairy/enhancer-of-split related with YRPW motif-like protein. (323 aa)
EXT1Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
ALX1ALX homeobox protein 1. (326 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
FGF8Fibroblast growth factor 8; Belongs to the heparin-binding growth factors family. (221 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (716 aa)
SEMA4Gsemaphorin-4G; Belongs to the semaphorin family. (774 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1353 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
SEMA6Dsemaphorin-6D; Belongs to the semaphorin family. (1073 aa)
SEMA4Bsemaphorin-4B isoform X1; Belongs to the semaphorin family. (827 aa)
HTR2BLOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 2B. (479 aa)
EFNA1ephrin-A1 isoform X2; Belongs to the ephrin family. (205 aa)
ADAM15ADAM metallopeptidase domain 15. (862 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (336 aa)
ENGEndoglin. (655 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X2; Belongs to the protein kinase superfamily. (433 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa)
ENSTTRP00000016529annotation not available (169 aa)
TBX20T-box transcription factor TBX20. (449 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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