STRINGSTRING
LRRC1 LRRC1 PLS1 PLS1 ENSTTRP00000009296 ENSTTRP00000009296 DVL2 DVL2 DFNB59 DFNB59 USH2A USH2A BMP4 BMP4 BCR BCR HESX1 HESX1 PTPN11 PTPN11 CYTL1 CYTL1 SOBP SOBP TCAP TCAP ENSTTRP00000007731 ENSTTRP00000007731 TRIP11 TRIP11 DLX5 DLX5 NOTCH1 NOTCH1 LHX3 LHX3 OTOP1 OTOP1 GBX2 GBX2 LGR5 LGR5 PTK7 PTK7 MKS1 MKS1 ENSTTRP00000006381 ENSTTRP00000006381 PRRX1 PRRX1 NOX3 NOX3 JAG1 JAG1 IFT88 IFT88 CXCL14 CXCL14 TIFAB TIFAB FZD3 FZD3 STRC STRC SOX9 SOX9 C1QTNF5 C1QTNF5 WDPCP WDPCP OTX1 OTX1 WNT5A WNT5A LOC101323724 LOC101323724 ADAM10 ADAM10 ALDH1A3 ALDH1A3 AHI1 AHI1 GATA3 GATA3 DCHS1 DCHS1 WNT1 WNT1 TBX2 TBX2 CHD7 CHD7 CELSR1 CELSR1 CLRN2 CLRN2 PHOX2B PHOX2B GLI3 GLI3 BMPER BMPER PROX1 PROX1 TBX3 TBX3 CHRNA9 CHRNA9 TTC39C TTC39C C1QB C1QB EPHB2 EPHB2 USH1G USH1G SLC9A3R1 SLC9A3R1 BMP2 BMP2 FRZB FRZB CECR2 CECR2 FOXI1 FOXI1 LRIG3 LRIG3 MCOLN3 MCOLN3 LRIG1 LRIG1 HES1 HES1 JAG2 JAG2 LRP10 LRP10 PAFAH1B1 PAFAH1B1 CCM2 CCM2 POU4F3 POU4F3 IFT20 IFT20 COL2A1 COL2A1 FGF9 FGF9 EPHA4 EPHA4 TMIE TMIE ATG4B ATG4B MCM2 MCM2 SCRIB SCRIB DVL1 DVL1 GRXCR1 GRXCR1 CLRN1 CLRN1 NEUROD1 NEUROD1 GRXCR2 GRXCR2 GSDME GSDME NTN1 NTN1 ENSTTRP00000015751 ENSTTRP00000015751 NAGLU NAGLU HEY2 HEY2 SEC24B SEC24B GABRB2 GABRB2 HMX2 HMX2 HMX3 HMX3 GRHL3 GRHL3 RIPOR2 RIPOR2 MYO6 MYO6 CTHRC1 CTHRC1 FZD6 FZD6 ATP8B1 ATP8B1 FREM2 FREM2 TPRN TPRN WHRN WHRN ENSTTRP00000014335 ENSTTRP00000014335 USH1C USH1C CDKN1B CDKN1B FGF8 FGF8 LIN7A LIN7A PTPRQ PTPRQ LHFPL5 LHFPL5 ROR1 ROR1 SLC44A4 SLC44A4 PCDH15 PCDH15 DLL1 DLL1 HPCA HPCA SIX4 SIX4 SIX1 SIX1 SHH SHH HHLA1 HHLA1 KCNQ1 KCNQ1 TFAP2A TFAP2A ATG5 ATG5 RPGRIP1L RPGRIP1L FGF20 FGF20 EYA1 EYA1 STOX1 STOX1 ATP6V1B1 ATP6V1B1 MAPKAPK2 MAPKAPK2 PAX8 PAX8 PLPPR4 PLPPR4 ZEB1 ZEB1 TTC8 TTC8 MAFB MAFB SPRY2 SPRY2 HPN HPN CDH23 CDH23 FGFR1-2 FGFR1-2 ANP32B ANP32B GABRA5 GABRA5 SLC4A7 SLC4A7 INSIG2 INSIG2 KCNQ4 KCNQ4 FGF10 FGF10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LRRC1Leucine-rich repeat-containing protein 1 isoform X1. (522 aa)
PLS1Plastin-1. (628 aa)
ENSTTRP00000009296annotation not available (181 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X9. (736 aa)
DFNB59Pejvakin. (352 aa)
USH2AUsherin isoform X1. (5216 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
BCRBCR activator of RhoGEF and GTPase. (1260 aa)
HESX1Homeobox expressed in ES cells 1 isoform X1. (132 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
CYTL1Cytokine-like protein 1. (108 aa)
SOBPSine oculis-binding protein homolog. (868 aa)
TCAPTitin-cap. (167 aa)
ENSTTRP00000007731annotation not available (287 aa)
TRIP11Thyroid receptor-interacting protein 11 isoform X1. (1979 aa)
DLX5Homeobox protein DLX-5. (289 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2527 aa)
LHX3LIM/homeobox protein Lhx3. (403 aa)
OTOP1Otopetrin-1 isoform X2. (549 aa)
GBX2Homeobox protein GBX-2 isoform X1. (348 aa)
LGR5Leucine-rich repeat-containing G-protein coupled receptor 5 isoform X1. (890 aa)
PTK7Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1070 aa)
MKS1Meckel syndrome type 1 protein. (559 aa)
ENSTTRP00000006381annotation not available (382 aa)
PRRX1Paired mesoderm homeobox protein 1. (164 aa)
NOX3NADPH oxidase 3. (568 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
IFT88Intraflagellar transport protein 88 homolog isoform X1. (827 aa)
CXCL14C-X-C motif chemokine 14 isoform X2. (109 aa)
TIFABTRAF-interacting protein with FHA domain-containing protein B. (162 aa)
FZD3Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
STRCStereocilin. (1764 aa)
SOX9Transcription factor SOX-9. (509 aa)
C1QTNF5C1q and TNF related 5. (243 aa)
WDPCPWD repeat-containing and planar cell polarity effector protein fritz homolog. (689 aa)
OTX1Homeobox protein OTX1. (355 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
LOC101323724Oncomodulin; Belongs to the parvalbumin family. (88 aa)
ADAM10Disintegrin and metalloproteinase domain-containing protein 10 isoform X1. (729 aa)
ALDH1A3Aldehyde dehydrogenase family 1 member A3 isoform X1; Belongs to the aldehyde dehydrogenase family. (478 aa)
AHI1Jouberin isoform X1. (1168 aa)
GATA3Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
DCHS1Protocadherin-16. (3134 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
TBX2T-box transcription factor TBX2. (703 aa)
CHD7chromodomain-helicase-DNA-binding protein 7 isoform X3. (2970 aa)
CELSR1Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (3004 aa)
CLRN2Clarin-2. (242 aa)
PHOX2BPaired mesoderm homeobox protein 2B. (234 aa)
GLI3Transcriptional activator GLI3. (1580 aa)
BMPERBMP-binding endothelial regulator protein. (640 aa)
PROX1Prospero homeobox protein 1. (744 aa)
TBX3T-box transcription factor TBX3. (742 aa)
CHRNA9Neuronal acetylcholine receptor subunit alpha-9. (480 aa)
TTC39CTetratricopeptide repeat protein 39C isoform X1. (520 aa)
C1QBComplement C1q B chain. (253 aa)
EPHB2Ephrin type-B receptor 2. (1031 aa)
USH1GUsher syndrome type-1G protein isoform X2. (519 aa)
SLC9A3R1SLC9A3 regulator 1. (359 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
FRZBSecreted frizzled-related protein 3. (325 aa)
CECR2Cat eye syndrome critical region protein 2 isoform X2. (1388 aa)
FOXI1Forkhead box protein I1. (371 aa)
LRIG3Leucine-rich repeats and immunoglobulin-like domains protein 3 isoform X2. (1073 aa)
MCOLN3Mucolipin-3 isoform X1. (551 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1023 aa)
HES1Transcription factor HES-1. (280 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1158 aa)
LRP10Low-density lipoprotein receptor-related protein 10. (712 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
CCM2CCM2 scaffold protein. (467 aa)
POU4F3POU domain protein. (338 aa)
IFT20LOW QUALITY PROTEIN: intraflagellar transport protein 20 homolog. (158 aa)
COL2A1Collagen type II alpha 1 chain. (1487 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
EPHA4Ephrin type-A receptor 4 isoform X1. (979 aa)
TMIETransmembrane inner ear expressed protein. (154 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (376 aa)
MCM2Minichromosome maintenance complex component 2. (905 aa)
SCRIBProtein scribble homolog. (1596 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
GRXCR1Glutaredoxin domain-containing cysteine-rich protein 1. (290 aa)
CLRN1Clarin-1. (232 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
GRXCR2Glutaredoxin domain-containing cysteine-rich protein 2. (246 aa)
GSDMENon-syndromic hearing impairment protein 5. (497 aa)
NTN1Netrin-1. (604 aa)
ENSTTRP00000015751annotation not available (328 aa)
NAGLUalpha-N-acetylglucosaminidase. (744 aa)
HEY2Hairy/enhancer-of-split related with YRPW motif protein 2. (336 aa)
SEC24BProtein transport protein Sec24B. (1253 aa)
GABRB2Gamma-aminobutyric acid receptor subunit beta-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
HMX2H6 family homeobox 2. (183 aa)
HMX3Homeobox protein HMX3. (357 aa)
GRHL3Grainyhead-like protein 3 homolog. (605 aa)
RIPOR2Protein FAM65B isoform X7. (1064 aa)
MYO6Unconventional myosin-VI isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1283 aa)
CTHRC1Collagen triple helix repeat-containing protein 1. (197 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (707 aa)
ATP8B1Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1177 aa)
FREM2FRAS1-related extracellular matrix protein 2. (3168 aa)
TPRNTaperin. (419 aa)
WHRNWhirlin. (901 aa)
ENSTTRP00000014335annotation not available (507 aa)
USH1CLOW QUALITY PROTEIN: harmonin. (895 aa)
CDKN1BCyclin-dependent kinase inhibitor 1B. (173 aa)
FGF8Fibroblast growth factor 8; Belongs to the heparin-binding growth factors family. (221 aa)
LIN7AProtein lin-7 homolog A isoform X1. (233 aa)
PTPRQPhosphatidylinositol phosphatase PTPRQ. (134 aa)
LHFPL5Tetraspan membrane protein of hair cell stereocilia isoform X2. (243 aa)
ROR1Inactive tyrosine-protein kinase transmembrane receptor ROR1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (937 aa)
SLC44A4Choline transporter-like protein 4; Belongs to the CTL (choline transporter-like) family. (711 aa)
PCDH15Protocadherin-15 isoform X4. (1939 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (784 aa)
HPCANeuron-specific calcium-binding protein hippocalcin. (193 aa)
SIX4Homeobox protein SIX4. (494 aa)
SIX1Homeobox protein SIX1. (284 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
HHLA1HERV-H LTR-associating protein 1. (629 aa)
KCNQ1Potassium voltage-gated channel subfamily KQT member 1. (673 aa)
TFAP2ATranscription factor AP-2-alpha isoform X6. (439 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
RPGRIP1LProtein fantom. (1255 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (589 aa)
STOX1Storkhead-box protein 1. (965 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. (513 aa)
MAPKAPK2MAP kinase-activated protein kinase 2. (400 aa)
PAX8Paired box protein Pax-8. (445 aa)
PLPPR4Phospholipid phosphatase-related protein type 4 isoform X2. (761 aa)
ZEB1Zinc finger E-box-binding homeobox 1 isoform X1. (1120 aa)
TTC8Tetratricopeptide repeat protein 8. (523 aa)
MAFBTranscription factor MafB. (323 aa)
SPRY2Protein sprouty homolog 2. (315 aa)
HPNHepsin. (526 aa)
CDH23Cadherin-23-like. (3357 aa)
FGFR1-2Fibroblast growth factor receptor 1. (692 aa)
ANP32BAcidic leucine-rich nuclear phosphoprotein 32 family member B. (235 aa)
GABRA5Gamma-aminobutyric acid receptor subunit alpha-5; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (460 aa)
SLC4A7Anion exchange protein. (1198 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (238 aa)
KCNQ4Potassium voltage-gated channel subfamily KQT member 4; Belongs to the potassium channel family. (589 aa)
FGF10Fibroblast growth factor 10. (142 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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