STRINGSTRING
DCDC1 DCDC1 FGF4 FGF4 ZZZ3 ZZZ3 E2F7 E2F7 PIK3C3 PIK3C3 DRD3 DRD3 CUL3 CUL3 NLRP5 NLRP5 FGF9 FGF9 ENSTTRP00000000710 ENSTTRP00000000710 PTN PTN PIN1 PIN1 ENSTTRP00000007731 ENSTTRP00000007731 PLK5 PLK5 KIF14 KIF14 RACK1 RACK1 GIPC1 GIPC1 FLCN FLCN KLHL9 KLHL9 ENTR1 ENTR1 TADA3 TADA3 DRD2 DRD2 DR1 DR1 TGFA TGFA VEGFD VEGFD KAT2A KAT2A PKP4 PKP4 KLHL21 KLHL21 KIF18B KIF18B RAB11FIP4 RAB11FIP4 CDC14B CDC14B GIPC3 GIPC3 E2F8 E2F8 CDC42 CDC42 FGF3 FGF3 KIF20A KIF20A WDR5 WDR5 PLK1 PLK1 PRC1 PRC1 VEGFC VEGFC AURKC AURKC FGF1 FGF1 SFRP2 SFRP2 WNT9B WNT9B FSD1L FSD1L PLK3 PLK3 YEATS2 YEATS2 AHCTF1 AHCTF1 CXCR5 CXCR5 MBIP MBIP MAP9 MAP9 CHMP4C CHMP4C PDGFA PDGFA PIK3R4 PIK3R4 CCP110 CCP110 PAX6 PAX6 DCDC1-2 DCDC1-2 ENSTTRP00000002013 ENSTTRP00000002013 BTC BTC SUSD2 SUSD2 RBL1 RBL1 PGF PGF THBS4 THBS4 BIRC6 BIRC6 FSD1 FSD1 CIT CIT OOEP OOEP CAT CAT YBX1 YBX1 PDGFB PDGFB CETN2 CETN2 ENSTTRP00000001124 ENSTTRP00000001124 RACGAP1 RACGAP1 ITGB1BP1 ITGB1BP1 SMYD5 SMYD5 SH3GLB1 SH3GLB1 PDXP PDXP RHOA RHOA CSPP1 CSPP1 NUP62CL NUP62CL TXNIP TXNIP CDC6 CDC6 KDF1 KDF1 SFN SFN SVIL SVIL KAT14 KAT14 BLM BLM GIT1 GIT1 MYC MYC CIB1 CIB1 HTR2B HTR2B SETD2 SETD2 ZFYVE26 ZFYVE26 IGF2 IGF2 EVI2B EVI2B GIPC2 GIPC2 CDC14A CDC14A TGFB3 TGFB3 EFHC1 EFHC1 C10orf99 C10orf99 NUP62 NUP62 PDGFD PDGFD AURKA AURKA PLK2 PLK2 ECT2 ECT2 HDGF HDGF KLHL13 KLHL13 PKN2 PKN2 DLL1 DLL1 SHH SHH TGFB2 TGFB2 ORC6 ORC6 CDK2AP2 CDK2AP2 PLK4 PLK4 INTU INTU TGFB1 TGFB1 RBL2 RBL2 PRDM15 PRDM15 NKX3-1 NKX3-1 ANKRD53 ANKRD53 MYO19 MYO19 INSC INSC RAB11A RAB11A PRKCE PRKCE SIRT2 SIRT2 BBS4 BBS4 INCENP INCENP BECN1 BECN1 TP63 TP63 TAS1R2 TAS1R2 ZFYVE19 ZFYVE19 PDGFC PDGFC IL1B IL1B IL1A IL1A GAREM1 GAREM1 PTCH1 PTCH1 BRCA2 BRCA2 AURKB AURKB VEGFB VEGFB GAREM2 GAREM2 VPS4A VPS4A UVRAG UVRAG MLLT3 MLLT3 CDC25B CDC25B RAB11FIP3 RAB11FIP3 FGF5 FGF5 VEGFA VEGFA TADA2A TADA2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DCDC1Doublecortin domain-containing protein 5. (672 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (147 aa)
ZZZ3ZZ-type zinc finger-containing protein 3 isoform X1. (903 aa)
E2F7Transcription factor E2F7. (904 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (885 aa)
DRD3D(3) dopamine receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
CUL3Cullin-3 isoform X1; Belongs to the cullin family. (745 aa)
NLRP5NACHT, LRR and PYD domains-containing protein 5. (1121 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
ENSTTRP00000000710annotation not available (306 aa)
PTNPleiotrophin isoform X1. (249 aa)
PIN1LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase NIMA-interacting 1. (162 aa)
ENSTTRP00000007731annotation not available (287 aa)
PLK5Polo like kinase 5. (335 aa)
KIF14Kinesin-like protein KIF14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1509 aa)
RACK1Receptor of activated protein C kinase 1. (346 aa)
GIPC1PDZ domain-containing protein GIPC1. (332 aa)
FLCNFolliculin isoform X2. (574 aa)
KLHL9Kelch-like protein 9. (617 aa)
ENTR1Serologically defined colon cancer antigen 3. (430 aa)
TADA3Transcriptional adapter 3. (425 aa)
DRD2D(2) dopamine receptor; Belongs to the G-protein coupled receptor 1 family. (445 aa)
DR1Protein Dr1. (176 aa)
TGFAProtransforming growth factor alpha isoform X1. (224 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
KAT2AHistone acetyltransferase KAT2A. (835 aa)
PKP4Plakophilin-4 isoform X1. (1192 aa)
KLHL21Kelch like family member 21. (596 aa)
KIF18BKinesin-like protein KIF18B isoform X1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (861 aa)
RAB11FIP4Rab11 family-interacting protein 4. (555 aa)
CDC14BDual specificity protein phosphatase CDC14B isoform X2. (498 aa)
GIPC3PDZ domain-containing protein GIPC3. (237 aa)
E2F8Transcription factor E2F8 isoform X1. (866 aa)
CDC42Cell division control protein 42 homolog. (156 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (159 aa)
KIF20AKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (890 aa)
WDR5WD repeat-containing protein 5B. (334 aa)
PLK1Serine/threonine-protein kinase PLK. (602 aa)
PRC1Protein regulator of cytokinesis 1 isoform X1. (616 aa)
VEGFCVascular endothelial growth factor C isoform X1; Belongs to the PDGF/VEGF growth factor family. (420 aa)
AURKCAurora kinase C isoform X1; Belongs to the protein kinase superfamily. (279 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
WNT9BWnt family member 9B. (330 aa)
FSD1LFSD1-like protein. (495 aa)
PLK3Serine/threonine-protein kinase PLK. (639 aa)
YEATS2YEATS domain-containing protein 2 isoform X2. (1400 aa)
AHCTF1Protein ELYS isoform X1. (2275 aa)
CXCR5C-X-C motif chemokine receptor 5. (374 aa)
MBIPMAP3K12-binding inhibitory protein 1 isoform X1. (344 aa)
MAP9Microtubule-associated protein 9. (456 aa)
CHMP4CCharged multivesicular body protein 4c. (237 aa)
PDGFAPlatelet-derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (196 aa)
PIK3R4Phosphoinositide 3-kinase regulatory subunit 4 isoform X1. (1357 aa)
CCP110Centriolar coiled-coil protein of 110 kDa isoform X1. (1013 aa)
PAX6Paired box protein Pax-6. (436 aa)
DCDC1-2Doublecortin domain-containing protein 1. (350 aa)
ENSTTRP00000002013annotation not available (500 aa)
BTCProbetacellulin isoform X2. (178 aa)
SUSD2Sushi domain-containing protein 2. (820 aa)
RBL1Retinoblastoma-like protein 1 isoform X2. (1067 aa)
PGFPlacenta growth factor; Belongs to the PDGF/VEGF growth factor family. (215 aa)
THBS4Thrombospondin-4. (948 aa)
BIRC6LOW QUALITY PROTEIN: baculoviral IAP repeat-containing protein 6. (4817 aa)
FSD1Fibronectin type III and SPRY domain-containing protein 1. (443 aa)
CITCitron Rho-interacting kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2055 aa)
OOEPOocyte-expressed protein homolog isoform X2. (140 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (526 aa)
YBX1Nuclease-sensitive element-binding protein 1 isoform X1. (316 aa)
PDGFBPlatelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa)
CETN2Centrin-2. (172 aa)
ENSTTRP00000001124annotation not available (522 aa)
RACGAP1Rac GTPase-activating protein 1-like. (632 aa)
ITGB1BP1Integrin beta-1-binding protein 1. (199 aa)
SMYD5SET and MYND domain-containing protein 5 isoform X1. (417 aa)
SH3GLB1endophilin-B1. (362 aa)
PDXPPyridoxal phosphate phosphatase; Belongs to the HAD-like hydrolase superfamily. (216 aa)
RHOATransforming protein RhoA. (193 aa)
CSPP1Centrosome and spindle pole-associated protein 1 isoform X1. (1254 aa)
NUP62CLNucleoporin-62 C-terminal-like protein. (267 aa)
TXNIPThioredoxin-interacting protein. (389 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (499 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
SFNStratifin. (248 aa)
SVILSupervillin isoform X8. (2175 aa)
KAT14Cysteine-rich protein 2-binding protein isoform X3. (694 aa)
BLMBloom syndrome protein isoform X1. (1409 aa)
GIT1ARF GTPase-activating protein GIT1. (697 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa)
CIB1Calcium and integrin binding 1. (191 aa)
HTR2BLOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 2B. (479 aa)
SETD2Histone-lysine N-methyltransferase SETD2. (2054 aa)
ZFYVE26Zinc finger FYVE domain-containing protein 26 isoform X4. (2476 aa)
IGF2Insulin-like growth factor II. (184 aa)
EVI2BProtein EVI2B. (451 aa)
GIPC2PDZ domain-containing protein GIPC2. (312 aa)
CDC14ADual specificity protein phosphatase CDC14A isoform X1. (622 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
EFHC1EF-hand domain-containing protein 1 isoform X1. (640 aa)
C10orf99Chromosome 10 open reading frame 99. (81 aa)
NUP62Nuclear pore glycoprotein p62. (516 aa)
PDGFDPlatelet-derived growth factor D isoform X1. (368 aa)
AURKAAurora kinase A isoform X1; Belongs to the protein kinase superfamily. (403 aa)
PLK2Serine/threonine-protein kinase PLK. (684 aa)
ECT2Protein ECT2 isoform X5. (914 aa)
HDGFHeparin binding growth factor. (247 aa)
KLHL13Kelch-like protein 13 isoform X1. (655 aa)
PKN2Serine/threonine-protein kinase N2 isoform X1. (917 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (784 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
ORC6Origin recognition complex subunit 6. (252 aa)
CDK2AP2Cyclin-dependent kinase 2-associated protein; Belongs to the CDK2AP family. (117 aa)
PLK4Serine/threonine-protein kinase PLK4 isoform X2. (973 aa)
INTUProtein inturned. (931 aa)
TGFB1Transforming growth factor beta 1. (338 aa)
RBL2Retinoblastoma-like protein 2. (1140 aa)
PRDM15PR domain zinc finger protein 15-like. (1330 aa)
NKX3-1Homeobox protein Nkx-3.1. (138 aa)
ANKRD53Ankyrin repeat domain-containing protein 53. (509 aa)
MYO19Unconventional myosin-XIX isoform X4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (766 aa)
INSCProtein inscuteable homolog isoform X2. (579 aa)
RAB11ARas-related protein Rab-11A. (215 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
SIRT2NAD-dependent protein deacetylase sirtuin-2. (379 aa)
BBS4Bardet-Biedl syndrome 4 protein. (516 aa)
INCENPInner centromere protein. (870 aa)
BECN1Beclin-1 isoform X2. (448 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
TAS1R2LOW QUALITY PROTEIN: taste receptor type 1 member 2. (761 aa)
ZFYVE19abscission/NoCut checkpoint regulator. (461 aa)
PDGFCPlatelet-derived growth factor C. (345 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (265 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (264 aa)
GAREM1GRB2-associated and regulator of MAPK protein 1 isoform X1. (806 aa)
PTCH1Protein patched homolog 1 isoform X1. (1313 aa)
BRCA2Breast cancer type 2 susceptibility protein. (3307 aa)
AURKBAurora kinase B isoform X4; Belongs to the protein kinase superfamily. (250 aa)
VEGFBVascular endothelial growth factor B isoform X1; Belongs to the PDGF/VEGF growth factor family. (172 aa)
GAREM2GRB2-associated and regulator of MAPK protein 2. (922 aa)
VPS4AVacuolar protein sorting-associated protein 4A isoform X1; Belongs to the AAA ATPase family. (433 aa)
UVRAGUV radiation resistance-associated gene protein isoform X1. (699 aa)
MLLT3Protein AF-9. (567 aa)
CDC25BCell division cycle 25B. (568 aa)
RAB11FIP3Rab11 family-interacting protein 3. (691 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (267 aa)
VEGFAVascular endothelial growth factor A. (402 aa)
TADA2ATranscriptional adapter 2-alpha. (438 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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