48 items (Tursiops truncatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DHRS3	Short-chain dehydrogenase/reductase 3 isoform X2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (301 aa)
	TBX2	T-box transcription factor TBX2. (703 aa)
	NKX2-5	Homeobox protein Nkx-2.5. (323 aa)
	SMAD7	Mothers against decapentaplegic homolog 7 isoform X1. (426 aa)
	CHD7	chromodomain-helicase-DNA-binding protein 7 isoform X3. (2970 aa)
	ZFPM2	Zinc finger protein ZFPM2. (1148 aa)
	SLIT3	Slit homolog 3 protein. (1521 aa)
	PROX1	Prospero homeobox protein 1. (744 aa)
	TBX3	T-box transcription factor TBX3. (742 aa)
	HAND1	Heart- and neural crest derivatives-expressed protein 1. (218 aa)
	DNAH11	LOW QUALITY PROTEIN: dynein heavy chain 11, axonemal. (4523 aa)
	CYR61	Protein CYR61. (382 aa)
	NOTCH2	Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa)
	PARVA	Alpha-parvin isoform X1. (371 aa)
	TBX5	T-box transcription factor TBX5. (519 aa)
	HES1	Transcription factor HES-1. (280 aa)
	RBM15	Putative RNA-binding protein 15. (975 aa)
	TBX20	T-box transcription factor TBX20. (449 aa)
	EGLN1	Egl nine homolog 1 isoform X1. (378 aa)
	ENG	Endoglin. (655 aa)
	HEY2	Hairy/enhancer-of-split related with YRPW motif protein 2. (336 aa)
	BMP7	Bone morphogenetic protein 7 isoform X2. (431 aa)
	APLNR	Apelin receptor; Belongs to the G-protein coupled receptor 1 family. (383 aa)
	FGF8	Fibroblast growth factor 8; Belongs to the heparin-binding growth factors family. (221 aa)
	NRP2	Neuropilin; Belongs to the neuropilin family. (931 aa)
	ZFPM1	Zinc finger protein ZFPM1. (984 aa)
	HEYL	Hairy/enhancer-of-split related with YRPW motif-like protein. (323 aa)
	NSD2	Histone-lysine N-methyltransferase NSD2. (1357 aa)
	TGFBR1	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (458 aa)
	CITED2	Cbp/p300-interacting transactivator 2. (272 aa)
	GATA6	Transcription factor GATA-6. (592 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
	GATA4	Transcription factor GATA-4 isoform X2. (442 aa)
	SMAD4	Mothers against decapentaplegic homolog. (407 aa)
	ISL1	Insulin gene enhancer protein ISL-1. (349 aa)
	SMAD6	SMAD family member 6. (492 aa)
	ENSTTRP00000009296	annotation not available (181 aa)
	SAV1	Protein salvador homolog 1. (385 aa)
	BMP4	Bone morphogenetic protein 4. (407 aa)
	SEMA3C	semaphorin-3C; Belongs to the semaphorin family. (751 aa)
	SMO	Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
	NOTCH1	Neurogenic locus notch homolog protein 1. (2527 aa)
	MKS1	Meckel syndrome type 1 protein. (559 aa)
	LRP2	Low-density lipoprotein receptor-related protein 2. (4599 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
	BMPR2	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	BMP7	ENSTTRP00000008787	ENSTTRP00000014836	Bone morphogenetic protein 4.	Bone morphogenetic protein 7 isoform X2.	0.863
BMP4	BMPR1A	ENSTTRP00000008787	ENSTTRP00000007678	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.995
BMP4	BMPR2	ENSTTRP00000008787	ENSTTRP00000004697	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.986
BMP4	FGF8	ENSTTRP00000008787	ENSTTRP00000014158	Bone morphogenetic protein 4.	Fibroblast growth factor 8; Belongs to the heparin-binding growth factors family.	0.670
BMP4	GATA4	ENSTTRP00000008787	ENSTTRP00000011331	Bone morphogenetic protein 4.	Transcription factor GATA-4 isoform X2.	0.721
BMP4	GATA6	ENSTTRP00000008787	ENSTTRP00000012663	Bone morphogenetic protein 4.	Transcription factor GATA-6.	0.662
BMP4	ISL1	ENSTTRP00000008787	ENSTTRP00000010273	Bone morphogenetic protein 4.	Insulin gene enhancer protein ISL-1.	0.550
BMP4	JAG1	ENSTTRP00000008787	ENSTTRP00000005880	Bone morphogenetic protein 4.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.718
BMP4	NKX2-5	ENSTTRP00000008787	ENSTTRP00000004234	Bone morphogenetic protein 4.	Homeobox protein Nkx-2.5.	0.493
BMP4	NOTCH1	ENSTTRP00000008787	ENSTTRP00000007173	Bone morphogenetic protein 4.	Neurogenic locus notch homolog protein 1.	0.417
BMP4	SMAD4	ENSTTRP00000008787	ENSTTRP00000011160	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.913
BMP4	SMAD6	ENSTTRP00000008787	ENSTTRP00000009705	Bone morphogenetic protein 4.	SMAD family member 6.	0.810
BMP4	SMAD7	ENSTTRP00000008787	ENSTTRP00000004100	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog 7 isoform X1.	0.793
BMP4	SMO	ENSTTRP00000008787	ENSTTRP00000008000	Bone morphogenetic protein 4.	Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family.	0.414
BMP4	TBX3	ENSTTRP00000008787	ENSTTRP00000003015	Bone morphogenetic protein 4.	T-box transcription factor TBX3.	0.522
BMP4	TBX5	ENSTTRP00000008787	ENSTTRP00000000924	Bone morphogenetic protein 4.	T-box transcription factor TBX5.	0.547
BMP4	TGFBR1	ENSTTRP00000008787	ENSTTRP00000012962	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.	0.835
BMP4	WNT11	ENSTTRP00000008787	ENSTTRP00000012600	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.474
BMP4	WNT5A	ENSTTRP00000008787	ENSTTRP00000004970	Bone morphogenetic protein 4.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.591
BMP7	BMP4	ENSTTRP00000014836	ENSTTRP00000008787	Bone morphogenetic protein 7 isoform X2.	Bone morphogenetic protein 4.	0.863