37 items (Tursiops truncatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TCF21	Transcription factor 21. (162 aa)
	NKX2-1	Homeobox protein Nkx-2.1. (394 aa)
	BMP4	Bone morphogenetic protein 4. (407 aa)
	RDH10	Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
	CTSZ	Cathepsin Z; Belongs to the peptidase C1 family. (303 aa)
	DLG5	Disks large homolog 5; Belongs to the MAGUK family. (1816 aa)
	HHIP	Hedgehog-interacting protein isoform X1. (700 aa)
	SRF	Serum response factor isoform X2. (509 aa)
	HOXA5	Homeobox A5. (268 aa)
	MAP2K1	Dual specificity mitogen-activated protein kinase kinase 1. (393 aa)
	WNT2	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
	FGF10	Fibroblast growth factor 10. (142 aa)
	SPRY2	Protein sprouty homolog 2. (315 aa)
	YAP1	Transcriptional coactivator YAP1 isoform X4. (488 aa)
	STK40	Serine/threonine-protein kinase 40. (440 aa)
	KRAS	GTPase KRas. (189 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1092 aa)
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
	EXT1	Exostosin-1; Belongs to the glycosyltransferase 47 family. (746 aa)
	ESRP2	Epithelial splicing regulatory protein 2. (717 aa)
	FGF8	Fibroblast growth factor 8; Belongs to the heparin-binding growth factors family. (221 aa)
	SPRY1	Protein sprouty homolog 1. (319 aa)
	SEC24B	Protein transport protein Sec24B. (1253 aa)
	CTSH	Cathepsin H. (335 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa)
	CTNNB1	Catenin beta-1. (781 aa)
	FOXF1	Forkhead box F1. (372 aa)
	GRHL2	Grainyhead-like protein 2 homolog isoform X4. (619 aa)
	SOX9	Transcription factor SOX-9. (509 aa)
	MAPK3	Mitogen-activated protein kinase 3. (382 aa)
	PLOD3	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3. (739 aa)
	TBX2	T-box transcription factor TBX2. (703 aa)
	CELSR1	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family. (3004 aa)
	LAMA1	Laminin subunit alpha-1. (3051 aa)
	NODAL	Nodal homolog. (348 aa)
	FOXA1	Hepatocyte nuclear factor 3-alpha. (442 aa)
	LIF	Leukemia inhibitory factor. (202 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	CTNNB1	ENSTTRP00000008787	ENSTTRP00000005764	Bone morphogenetic protein 4.	Catenin beta-1.	0.688
BMP4	FGF10	ENSTTRP00000008787	ENSTTRP00000009805	Bone morphogenetic protein 4.	Fibroblast growth factor 10.	0.819
BMP4	FGF8	ENSTTRP00000008787	ENSTTRP00000014158	Bone morphogenetic protein 4.	Fibroblast growth factor 8; Belongs to the heparin-binding growth factors family.	0.670
BMP4	FOXF1	ENSTTRP00000008787	ENSTTRP00000005561	Bone morphogenetic protein 4.	Forkhead box F1.	0.555
BMP4	LIF	ENSTTRP00000008787	ENSTTRP00000001444	Bone morphogenetic protein 4.	Leukemia inhibitory factor.	0.562
BMP4	SHH	ENSTTRP00000008787	ENSTTRP00000013015	Bone morphogenetic protein 4.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.765
BMP4	SOX9	ENSTTRP00000008787	ENSTTRP00000005370	Bone morphogenetic protein 4.	Transcription factor SOX-9.	0.664
BMP4	SPRY2	ENSTTRP00000008787	ENSTTRP00000011048	Bone morphogenetic protein 4.	Protein sprouty homolog 2.	0.491
CELSR1	SEC24B	ENSTTRP00000003919	ENSTTRP00000015459	Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.	Protein transport protein Sec24B.	0.418
CTNNB1	BMP4	ENSTTRP00000005764	ENSTTRP00000008787	Catenin beta-1.	Bone morphogenetic protein 4.	0.688
CTNNB1	DLG5	ENSTTRP00000005764	ENSTTRP00000007372	Catenin beta-1.	Disks large homolog 5; Belongs to the MAGUK family.	0.505
CTNNB1	FGF10	ENSTTRP00000005764	ENSTTRP00000009805	Catenin beta-1.	Fibroblast growth factor 10.	0.576
CTNNB1	FGF8	ENSTTRP00000005764	ENSTTRP00000014158	Catenin beta-1.	Fibroblast growth factor 8; Belongs to the heparin-binding growth factors family.	0.552
CTNNB1	KRAS	ENSTTRP00000005764	ENSTTRP00000011954	Catenin beta-1.	GTPase KRas.	0.705
CTNNB1	MAPK1	ENSTTRP00000005764	ENSTTRP00000015859	Catenin beta-1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.650
CTNNB1	MAPK3	ENSTTRP00000005764	ENSTTRP00000005227	Catenin beta-1.	Mitogen-activated protein kinase 3.	0.644
CTNNB1	SHH	ENSTTRP00000005764	ENSTTRP00000013015	Catenin beta-1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.683
CTNNB1	SOX9	ENSTTRP00000005764	ENSTTRP00000005370	Catenin beta-1.	Transcription factor SOX-9.	0.920
CTNNB1	WNT2	ENSTTRP00000005764	ENSTTRP00000009799	Catenin beta-1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.752
CTNNB1	YAP1	ENSTTRP00000005764	ENSTTRP00000011064	Catenin beta-1.	Transcriptional coactivator YAP1 isoform X4.	0.839