node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
JMJD1C | KDM4B | ENSTTRP00000006797 | ENSTTRP00000016023 | Probable JmjC domain-containing histone demethylation protein 2C isoform X1. | Lysine-specific demethylase 4B. | 0.418 |
JMJD1C | KDM5C | ENSTTRP00000006797 | ENSTTRP00000004859 | Probable JmjC domain-containing histone demethylation protein 2C isoform X1. | Lysine-specific demethylase 5C isoform X2. | 0.493 |
JMJD1C | KDM7A | ENSTTRP00000006797 | ENSTTRP00000009023 | Probable JmjC domain-containing histone demethylation protein 2C isoform X1. | Lysine-specific demethylase 7A isoform X1. | 0.720 |
JMJD1C | PHF8 | ENSTTRP00000006797 | ENSTTRP00000000351 | Probable JmjC domain-containing histone demethylation protein 2C isoform X1. | Histone lysine demethylase PHF8 isoform X1. | 0.570 |
KDM1A | KDM1B | ENSTTRP00000007320 | ENSTTRP00000006759 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Lysine-specific histone demethylase 1B isoform X1. | 0.632 |
KDM1A | KDM2B | ENSTTRP00000007320 | ENSTTRP00000013558 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | LOW QUALITY PROTEIN: lysine-specific demethylase 2B. | 0.581 |
KDM1A | KDM3A | ENSTTRP00000007320 | ENSTTRP00000009851 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Lysine-specific demethylase 3A. | 0.590 |
KDM1A | KDM3B | ENSTTRP00000007320 | ENSTTRP00000005174 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Lysine-specific demethylase 3B isoform X1. | 0.557 |
KDM1A | KDM4A | ENSTTRP00000007320 | ENSTTRP00000002230 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Lysine-specific demethylase 4A. | 0.913 |
KDM1A | KDM4B | ENSTTRP00000007320 | ENSTTRP00000016023 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Lysine-specific demethylase 4B. | 0.741 |
KDM1A | KDM5A | ENSTTRP00000007320 | ENSTTRP00000008413 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Lysine-specific demethylase 5A isoform X6. | 0.605 |
KDM1A | KDM5B | ENSTTRP00000007320 | ENSTTRP00000001014 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Lysine-specific demethylase 5B isoform X1. | 0.592 |
KDM1A | KDM5C | ENSTTRP00000007320 | ENSTTRP00000004859 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Lysine-specific demethylase 5C isoform X2. | 0.476 |
KDM1A | KDM6A | ENSTTRP00000007320 | ENSTTRP00000006394 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Lysine-specific demethylase 6A isoform X4. | 0.430 |
KDM1A | KDM6B | ENSTTRP00000007320 | ENSTTRP00000009761 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Dynein heavy chain 2, axonemal. | 0.471 |
KDM1A | KDM7A | ENSTTRP00000007320 | ENSTTRP00000009023 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Lysine-specific demethylase 7A isoform X1. | 0.589 |
KDM1B | KDM1A | ENSTTRP00000006759 | ENSTTRP00000007320 | Lysine-specific histone demethylase 1B isoform X1. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.632 |
KDM1B | KDM2B | ENSTTRP00000006759 | ENSTTRP00000013558 | Lysine-specific histone demethylase 1B isoform X1. | LOW QUALITY PROTEIN: lysine-specific demethylase 2B. | 0.482 |
KDM1B | KDM3B | ENSTTRP00000006759 | ENSTTRP00000005174 | Lysine-specific histone demethylase 1B isoform X1. | Lysine-specific demethylase 3B isoform X1. | 0.521 |
KDM1B | KDM4A | ENSTTRP00000006759 | ENSTTRP00000002230 | Lysine-specific histone demethylase 1B isoform X1. | Lysine-specific demethylase 4A. | 0.547 |