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| | RGS9 | Regulator of G protein signaling 9. (663 aa) |
| | F11R | Junctional adhesion molecule A isoform X1. (298 aa) |
| | XRCC5 | X-ray repair cross-complementing protein 5 isoform X1. (733 aa) |
| | CASP8 | Caspase-8 isoform X2; Belongs to the peptidase C14A family. (491 aa) |
| | CRB1 | Protein crumbs homolog 1. (1405 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (746 aa) |
| | ENSTTRP00000008101 | annotation not available (454 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (657 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (315 aa) |
| | SPIDR | DNA repair-scaffolding protein isoform X1. (900 aa) |
| | BRCC3 | Lys-63-specific deubiquitinase BRCC36 isoform X1. (317 aa) |
| | NEDD4 | E3 ubiquitin-protein ligase. (1193 aa) |
| | YBX3 | Y-box-binding protein 3 isoform X1. (264 aa) |
| | BNIP3 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3. (180 aa) |
| | FAS | Tumor necrosis factor receptor superfamily member 6 isoform X2. (350 aa) |
| | OPN4 | Opsin 4. (443 aa) |
| | CASP10 | Caspase-10; Belongs to the peptidase C14A family. (515 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (869 aa) |
| | SLC38A3 | Sodium-coupled neutral amino acid transporter 3. (504 aa) |
| | GNAT1 | Guanine nucleotide-binding protein G(T) subunit alpha-1. (350 aa) |
| | ACTR5 | Actin-related protein 5; Belongs to the actin family. (482 aa) |
| | TMEM161A | LOW QUALITY PROTEIN: transmembrane protein 161A. (342 aa) |
| | SLC12A6 | Solute carrier family 12 member 6 isoform X2. (1125 aa) |
| | NEUROD2 | Neuronal differentiation 2. (382 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (212 aa) |
| | HYAL2 | Hyaluronidase. (476 aa) |
| | HYAL1 | Hyaluronidase. (432 aa) |
| | HYAL3 | Hyaluronidase. (459 aa) |
| | XRCC6 | X-ray repair cross-complementing protein 6 isoform X2. (609 aa) |
| | TANK | TRAF family member-associated NF-kappa-B activator isoform X6. (425 aa) |
| | HSF1 | Heat shock transcription factor 1. (476 aa) |
| | SCX | Scleraxis bHLH transcription factor. (203 aa) |
| | POLH | DNA polymerase eta isoform X2. (708 aa) |
| | GTF2H5 | General transcription factor IIH subunit 5. (71 aa) |
| | MAP3K14 | Mitogen-activated protein kinase kinase kinase 14. (953 aa) |
| | PIEZO1 | Piezo-type mechanosensitive ion channel component 1. (2046 aa) |
| | SCNN1G | Amiloride-sensitive sodium channel subunit gamma; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (651 aa) |
| | GNB5 | Guanine nucleotide-binding protein subunit beta-5. (395 aa) |
| | ZMPSTE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa) |
| | TNFSF14 | Tumor necrosis factor ligand superfamily member 14. (241 aa) |
| | CUNH9orf116 | UPF0691 protein C9orf116 homolog. (136 aa) |
| | BMF | Bcl-2-modifying factor isoform X1. (184 aa) |
| | STK39 | STE20/SPS1-related proline-alanine-rich protein kinase isoform X1. (538 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase 1. (1011 aa) |
| | CHEK1 | Serine/threonine-protein kinase Chk1 isoform X1; Belongs to the protein kinase superfamily. (475 aa) |
| | GPLD1 | Phosphatidylinositol-glycan-specific phospholipase D isoform X2. (811 aa) |
| | SLC9A1 | Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (809 aa) |
| | aqp1 | Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (251 aa) |
| | CD40 | Tumor necrosis factor receptor superfamily member 5. (280 aa) |
| | XPA | DNA repair protein complementing XP-A cells. (273 aa) |
| | ZBTB1 | Zinc finger and BTB domain-containing protein 1. (713 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]. (622 aa) |
| | CLOCK | Circadian locomoter output cycles protein kaput. (845 aa) |
| | AQP2 | Aquaporin-2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa) |
| | AQP5 | Aquaporin 5. (261 aa) |
| | ASIC1 | Acid-sensing ion channel 1; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (562 aa) |
| | SFRP1 | Secreted frizzled-related protein 1 isoform X2. (307 aa) |
| | MMP2 | 72 kDa type IV collagenase. (657 aa) |
| | TRPV1 | Transient receptor potential cation channel subfamily V member 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (843 aa) |
| | TRPM1 | Transient receptor potential cation channel subfamily M member 1 isoform X2. (1601 aa) |
| | POLD3 | DNA polymerase delta subunit 3 isoform X1. (465 aa) |
| | PTPRK | Receptor-type tyrosine-protein phosphatase kappa. (1338 aa) |
| | SOX9 | Transcription factor SOX-9. (509 aa) |
| | MAPK3 | Mitogen-activated protein kinase 3. (382 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (509 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1462 aa) |
| | MYD88 | MYD88 innate immune signal transduction adaptor. (296 aa) |
| | RHNO1 | RAD9, HUS1, RAD1-interacting nuclear orphan protein 1. (240 aa) |
| | KCNK18 | Potassium two pore domain channel subfamily K member 18. (377 aa) |
| | SCNN1B | Amiloride-sensitive sodium channel subunit beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (683 aa) |
| | PBK | Lymphokine-activated killer T-cell-originated protein kinase. (198 aa) |
| | RS1 | Retinoschisin. (224 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (443 aa) |
| | BCL10 | B-cell lymphoma/leukemia 10. (233 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3043 aa) |
| | SFRP2 | Secreted frizzled-related protein 2. (294 aa) |
| | FBXO4 | F-box only protein 4 isoform X1. (387 aa) |
| | LRRC8D | Volume-regulated anion channel subunit LRRC8D. (855 aa) |
| | OPN5 | Opsin-5; Belongs to the G-protein coupled receptor 1 family. (310 aa) |
| | ENSTTRP00000003732 | annotation not available (574 aa) |
| | MCOLN1 | Mucolipin-1. (578 aa) |
| | REST | RE1-silencing transcription factor. (656 aa) |
| | BDKRB2 | B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (392 aa) |
| | TNFRSF8 | Tumor necrosis factor receptor superfamily member 8. (589 aa) |
| | ZFP36L1 | mRNA decay activator protein ZFP36L1. (338 aa) |
| | EP300 | Histone acetyltransferase p300. (2422 aa) |
| | CRADD | Death domain-containing protein CRADD isoform X1. (199 aa) |
| | RAD1 | Cell cycle checkpoint protein RAD1 isoform X1. (278 aa) |
| | TLR8 | Toll-like receptor 8; Belongs to the Toll-like receptor family. (1054 aa) |
| | TLR7 | Toll-like receptor 7 isoform X2. (1050 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (731 aa) |
| | PDE2A | Phosphodiesterase. (936 aa) |
| | CUL4B | cullin-4B; Belongs to the cullin family. (892 aa) |
| | RPE65 | Retinoid isomerohydrolase. (533 aa) |
| | IRF1 | Interferon regulatory factor. (318 aa) |
| | CAPN3 | Calpain-3; Belongs to the peptidase C2 family. (822 aa) |
| | POLD1 | LOW QUALITY PROTEIN: DNA polymerase delta catalytic subunit. (1125 aa) |
| | PRKCD | Protein kinase C delta. (671 aa) |
| | ENSTTRP00000002090 | annotation not available (193 aa) |
| | TNKS1BP1 | 182 kDa tankyrase-1-binding protein. (1707 aa) |
| | INTS7 | Integrator complex subunit 7. (930 aa) |
| | DDX3X | ATP-dependent RNA helicase DDX3X; Belongs to the DEAD box helicase family. (645 aa) |
| | SLC24A4 | Sodium/potassium/calcium exchanger 4 isoform X2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (547 aa) |
| | CNN2 | Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (309 aa) |
| | MAP3K2 | Mitogen-activated protein kinase kinase kinase 2. (559 aa) |
| | CREBBP | CREB-binding protein isoform X6. (2402 aa) |
| | BAG3 | BAG family molecular chaperone regulator 3 isoform X2. (576 aa) |
| | DHX36 | ATP-dependent RNA helicase DHX36 isoform X1. (1012 aa) |
| | PASD1 | Circadian clock protein PASD1. (620 aa) |
| | ENSTTRP00000015784 | annotation not available (149 aa) |
| | ENSTTRP00000015677 | annotation not available (289 aa) |
| | BLM | Bloom syndrome protein isoform X1. (1409 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa) |
| | PPID | LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase D-like. (370 aa) |
| | SIRT1 | NAD-dependent protein deacetylase sirtuin-1 isoform X1. (616 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (732 aa) |
| | RIPOR2 | Protein FAM65B isoform X7. (1064 aa) |
| | N4BP1 | NEDD4-binding protein 1 isoform X2. (830 aa) |
| | CDC25A | M-phase inducer phosphatase 1 isoform X1. (523 aa) |
| | NIPBL | Nipped-B protein. (2801 aa) |
| | AQP10 | LOW QUALITY PROTEIN: aquaporin-10; Belongs to the MIP/aquaporin (TC 1.A.8) family. (294 aa) |
| | RDH11 | Retinol dehydrogenase 11 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | ENSTTRP00000014985 | annotation not available (90 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit 1. (315 aa) |
| | CASP9 | Caspase-9; Belongs to the peptidase C14A family. (365 aa) |
| | TLR3 | Toll-like receptor 3 isoform X1; Belongs to the Toll-like receptor family. (904 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase MLT isoform X1. (800 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (187 aa) |
| | ENSTTRP00000014547 | annotation not available (387 aa) |
| | PIEZO2 | Piezo-type mechanosensitive ion channel component. (506 aa) |
| | METTL3 | N6-adenosine-methyltransferase 70 kDa subunit; Belongs to the MT-A70-like family. (578 aa) |
| | PKD2 | Polycystin-2 isoform X2. (975 aa) |
| | HVCN1 | Voltage-gated hydrogen channel 1 isoform X1. (257 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (420 aa) |
| | RGR | RPE-retinal G protein-coupled receptor isoform X1; Belongs to the G-protein coupled receptor 1 family. Opsin subfamily. (253 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa) |
| | RHBDD1 | Rhomboid-related protein 4. (315 aa) |
| | STK11 | Serine/threonine-protein kinase STK11 isoform X3. (340 aa) |
| | ECT2 | Protein ECT2 isoform X5. (914 aa) |
| | ANKRD1 | Ankyrin repeat domain-containing protein 1. (318 aa) |
| | IMPACT | Protein IMPACT isoform X3. (319 aa) |
| | OPN1SW | LOW QUALITY PROTEIN: short-wave-sensitive opsin 1. (340 aa) |
| | INSRR | Insulin receptor-related protein. (1300 aa) |
| | NET1 | Neuroepithelial cell-transforming gene 1 protein isoform X2. (556 aa) |
| | LTBR | Tumor necrosis factor receptor superfamily member 3. (429 aa) |
| | SCNN1A | Amiloride-sensitive sodium channel subunit alpha; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (539 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (439 aa) |
| | GRB2 | Growth factor receptor-bound protein 2. (156 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | DDB2 | DNA damage-binding protein 2 isoform X3. (426 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1067 aa) |
| | NOX1 | LOW QUALITY PROTEIN: NADPH oxidase 1. (558 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (262 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa) |
| | RAD9A | RAD9 checkpoint clamp component A. (390 aa) |
| | TP53INP1 | Tumor protein p53-inducible nuclear protein 1 isoform X1. (240 aa) |
| | TGFB1 | Transforming growth factor beta 1. (338 aa) |
| | LIG4 | DNA ligase. (911 aa) |
| | TLK2 | Serine/threonine-protein kinase tousled-like 2 isoform X4. (766 aa) |
| | BABAM2 | BRCA1-A complex subunit BRE. (411 aa) |
| | SDE2 | Protein SDE2 homolog isoform X1. (418 aa) |
| | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 isoform X1; Belongs to the protein kinase superfamily. (360 aa) |
| | WRN | Werner syndrome ATP-dependent helicase isoform X2. (1352 aa) |
| | GNA11 | G protein subunit alpha 11. (359 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2. (603 aa) |
| | MMP9 | Matrix metalloproteinase-9. (670 aa) |
| | DHRS12 | Dehydrogenase/reductase SDR family member 12. (264 aa) |
| | PKD2L1 | LOW QUALITY PROTEIN: polycystic kidney disease 2-like 1 protein. (797 aa) |
| | RP1 | Oxygen-regulated protein 1. (2148 aa) |
| | CHEK2 | Serine/threonine-protein kinase Chk2 isoform X2. (580 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1825 aa) |
| | OPN3 | Opsin 3. (392 aa) |
| | TRPV4 | Transient receptor potential cation channel subfamily V member 4-like. (591 aa) |
| | YAP1 | Transcriptional coactivator YAP1 isoform X4. (488 aa) |
| | INO80 | DNA helicase INO80 isoform X1. (1536 aa) |
| | WNK3 | Serine/threonine-protein kinase WNK3 isoform X1. (1759 aa) |
| | RHO | Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Signaling mediates the activation of phospholipase C (By similarity). Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by arrestin and terminates signaling (By similarity). (348 aa) |
| | MAP3K1 | Mitogen-activated protein kinase kinase kinase 1 isoform X1. (1469 aa) |
| | XPC | DNA repair protein complementing XP-C cells. (907 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | RAD51AP1 | RAD51-associated protein 1 isoform X1. (345 aa) |
| | DDB1 | DNA damage-binding protein 1 isoform X1. (1118 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (265 aa) |
| | EPO | Erythropoietin. (192 aa) |
| | PTGER4 | Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family. (484 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa) |
| | LOC101333926 | RE1-silencing transcription factor-like. (974 aa) |
| | CASP2 | Caspase-2 isoform X2; Belongs to the peptidase C14A family. (452 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (299 aa) |
| | BRCA2 | Breast cancer type 2 susceptibility protein. (3307 aa) |
| | USP47 | Ubiquitin carboxyl-terminal hydrolase 47 isoform X1; Belongs to the peptidase C19 family. (1362 aa) |
| | CRYAB | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa) |
| | NUCKS1 | Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 isoform X1. (306 aa) |
| | PLEC | Plectin. (4664 aa) |
| | MFAP4 | Microfibril associated protein 4. (272 aa) |
| | AURKB | Aurora kinase B isoform X4; Belongs to the protein kinase superfamily. (250 aa) |
| | KCNK4 | Potassium channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (394 aa) |
| | BAD | BCL2 associated agonist of cell death. (150 aa) |
| | ENSTTRP00000009732 | annotation not available (544 aa) |
| | LRRC8E | Volume-regulated anion channel subunit LRRC8E. (795 aa) |
| | ATR | Serine/threonine-protein kinase ATR isoform X2; Belongs to the PI3/PI4-kinase family. (2623 aa) |
| | TIMP1 | Metalloproteinase inhibitor 1 isoform X1. (196 aa) |
| | GRM1 | Metabotropic glutamate receptor 1 isoform X1. (1195 aa) |
| | SLC2A4 | Solute carrier family 2 member 4. (505 aa) |
| | RAB11B | RAB11B, member RAS oncogene family. (218 aa) |
| | POLK | DNA polymerase kappa. (871 aa) |
| | SLC4A11 | Sodium bicarbonate transporter-like protein 11 isoform X1. (915 aa) |
| | ERCC4 | DNA repair endonuclease XPF. (914 aa) |
| | GPR88 | Probable G-protein coupled receptor 88. (383 aa) |
