STRINGSTRING
BMP10 BMP10 ENSTTRP00000012809 ENSTTRP00000012809 KIAA1324L KIAA1324L LDLRAD4 LDLRAD4 SLC2A10 SLC2A10 SMAD7 SMAD7 GDF10 GDF10 WFIKKN1 WFIKKN1 BMP4 BMP4 SNW1 SNW1 SCUBE3 SCUBE3 CUNH20orf27 CUNH20orf27 NKX2-1 NKX2-1 ENSTTRP00000009086 ENSTTRP00000009086 ING2 ING2 DACT2 DACT2 CDKN1C CDKN1C GDF11 GDF11 ENSTTRP00000009296 ENSTTRP00000009296 SOSTDC1 SOSTDC1 SKI SKI GDF2 GDF2 ONECUT1 ONECUT1 PBLD PBLD SPRED1 SPRED1 INHBE INHBE INHBC INHBC ONECUT2 ONECUT2 FERMT1 FERMT1 TGFB1 TGFB1 CHRDL1 CHRDL1 TGFB1I1 TGFB1I1 LATS2 LATS2 CILP2 CILP2 SFRP5 SFRP5 ZNF451 ZNF451 SMAD6 SMAD6 LOC101317021 LOC101317021 FGF10 FGF10 FOLR1 FOLR1 CDH5 CDH5 UCMA UCMA CHRD CHRD SULF1 SULF1 FSTL3 FSTL3 DLX1 DLX1 LOC101325454 LOC101325454 GDF1 GDF1 CRB2 CRB2 SPRY2 SPRY2 DAB2 DAB2 SMAD4 SMAD4 ZEB1 ZEB1 MSX1 MSX1 LEMD3 LEMD3 FST FST GDF6 GDF6 ENSTTRP00000011729 ENSTTRP00000011729 RBPMS RBPMS CITED1 CITED1 CAV3 CAV3 LATS1 LATS1 GPC3 GPC3 THBS1 THBS1 CDKN2B CDKN2B ZNF423 ZNF423 NOTCH2 NOTCH2 GLG1 GLG1 FGF9 FGF9 PMEPA1 PMEPA1 GDF3 GDF3 ENSTTRP00000000710 ENSTTRP00000000710 SFRP1 SFRP1 TMPRSS6 TMPRSS6 CYR61 CYR61 TNFAIP6 TNFAIP6 HES1 HES1 LRG1 LRG1 PELO PELO SKIL SKIL ENSTTRP00000002026 ENSTTRP00000002026 FAM89B FAM89B KDR KDR BMP2 BMP2 TRIM33 TRIM33 WFIKKN2 WFIKKN2 TOB1 TOB1 SORL1 SORL1 ACVR1B ACVR1B MYOCD MYOCD BCL9L BCL9L SMURF1 SMURF1 SMAD3 SMAD3 SKOR1 SKOR1 BAMBI BAMBI NODAL NODAL EP300 EP300 PRDM16 PRDM16 STRAP STRAP BMPER BMPER INHBA INHBA CIDEA CIDEA IL17F IL17F SDCBP SDCBP TFAP2B TFAP2B SPART SPART HTRA3 HTRA3 NUMA1 NUMA1 BMP3 BMP3 PPARA PPARA NUP93 NUP93 LEMD2 LEMD2 ZBTB7A ZBTB7A LRP2 LRP2 LTBP1 LTBP1 DAND5 DAND5 IL17RD IL17RD AXIN1 AXIN1 PPM1A PPM1A MEN1 MEN1 SMURF2 SMURF2 VASN VASN CAV1 CAV1 PIN1 PIN1 CAV2 CAV2 ENSTTRP00000007925 ENSTTRP00000007925 ASPN ASPN PDPK1 PDPK1 BMPR1A BMPR1A CER1 CER1 GIPC1 GIPC1 SH2B1 SH2B1 CHRDL2 CHRDL2 GIPC3 GIPC3 BMP5 BMP5 CHST11 CHST11 ITGA3 ITGA3 WNT5A WNT5A RNF111 RNF111 HTRA1 HTRA1 CRIM1 CRIM1 EMILIN1 EMILIN1 SOX11 SOX11 GDF15 GDF15 HSPA5 HSPA5 TBX20 TBX20 CILP CILP VWC2 VWC2 HJV HJV GDF5 GDF5 CREBBP CREBBP FBN2 FBN2 ZNF703 ZNF703 HFE HFE FSTL1 FSTL1 ENG ENG ACVR2A ACVR2A SKOR2 SKOR2 KIAA0319 KIAA0319 SIRT1 SIRT1 BMP6 BMP6 UBE2O UBE2O MPP5 MPP5 RASL11B RASL11B NEO1 NEO1 BMP7 BMP7 FBN1 FBN1 UBL3 UBL3 GIPC2 GIPC2 TGFB3 TGFB3 CTDSPL2 CTDSPL2 SPRY1 SPRY1 ABL1 ABL1 HIPK2 HIPK2 ZC3H3 ZC3H3 STK11 STK11 BMPR2 BMPR2 ACVRL1 ACVRL1 NPNT NPNT ILK ILK WNT1 WNT1 SNX25 SNX25 SFRP2 SFRP2 NBL1 NBL1 TWSG1 TWSG1 ENSTTRP00000013860 ENSTTRP00000013860 LOC101331122 LOC101331122 VEPH1 VEPH1 LOC101327238 LOC101327238 CD109 CD109 ADAMTSL2 ADAMTSL2 INHBB INHBB CSNK2B CSNK2B RNF165 RNF165 TGFBR3 TGFBR3 NRROS NRROS TGFBR1 TGFBR1 CITED2 CITED2 FLCN FLCN LOX LOX VWC2L VWC2L DLX6 DLX6 NOTCH1 NOTCH1 TGFB2 TGFB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMP10Bone morphogenetic protein 10. (423 aa)
ENSTTRP00000012809annotation not available (161 aa)
KIAA1324LUPF0577 protein KIAA1324-like homolog. (802 aa)
LDLRAD4LOW QUALITY PROTEIN: low-density lipoprotein receptor class A domain-containing protein 4. (324 aa)
SLC2A10Solute carrier family 2, facilitated glucose transporter member 10; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (513 aa)
SMAD7Mothers against decapentaplegic homolog 7 isoform X1. (426 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (476 aa)
WFIKKN1WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1. (550 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
SNW1SNW domain-containing protein 1. (536 aa)
SCUBE3Signal peptide, CUB and EGF-like domain-containing protein 1. (1007 aa)
CUNH20orf27UPF0687 protein C20orf27 homolog. (343 aa)
NKX2-1Homeobox protein Nkx-2.1. (394 aa)
ENSTTRP00000009086annotation not available (269 aa)
ING2Inhibitor of growth protein. (222 aa)
DACT2Dapper homolog 2. (675 aa)
CDKN1CCyclin-dependent kinase inhibitor 1C. (249 aa)
GDF11Growth differentiation factor 11. (313 aa)
ENSTTRP00000009296annotation not available (181 aa)
SOSTDC1Sclerostin domain-containing protein 1. (229 aa)
SKISki oncogene. (633 aa)
GDF2Growth/differentiation factor 2. (431 aa)
ONECUT1One cut homeobox 1. (465 aa)
PBLDPhenazine biosynthesis-like domain-containing protein. (288 aa)
SPRED1Sprouty-related, EVH1 domain-containing protein 1. (436 aa)
INHBEInhibin subunit beta E. (351 aa)
INHBCInhibin beta C chain. (247 aa)
ONECUT2One cut domain family member 2. (419 aa)
FERMT1Fermitin family homolog 1 isoform X1. (677 aa)
TGFB1Transforming growth factor beta 1. (338 aa)
CHRDL1Chordin-like protein 1 isoform X3. (457 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein. (456 aa)
LATS2Large tumor suppressor kinase 2. (992 aa)
CILP2Cartilage intermediate layer protein 2. (1155 aa)
SFRP5Secreted frizzled-related protein 5. (252 aa)
ZNF451E3 SUMO-protein ligase ZNF451 isoform X1. (1024 aa)
SMAD6SMAD family member 6. (492 aa)
LOC101317021Nodal modulator 1. (1260 aa)
FGF10Fibroblast growth factor 10. (142 aa)
FOLR1Folate receptor gamma. (251 aa)
CDH5Cadherin-5. (779 aa)
UCMAUnique cartilage matrix-associated protein. (138 aa)
CHRDChordin. (908 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
FSTL3Follistatin like 3. (262 aa)
DLX1Distal-less homeobox 1. (255 aa)
LOC101325454Bone morphogenetic protein 8B. (241 aa)
GDF1Embryonic growth/differentiation factor 1. (370 aa)
CRB2Crumbs cell polarity complex component 2. (1254 aa)
SPRY2Protein sprouty homolog 2. (315 aa)
DAB2Disabled homolog 2 isoform X2. (753 aa)
SMAD4Mothers against decapentaplegic homolog. (407 aa)
ZEB1Zinc finger E-box-binding homeobox 1 isoform X1. (1120 aa)
MSX1Homeobox protein MSX-1. (303 aa)
LEMD3Inner nuclear membrane protein Man1 isoform X1. (904 aa)
FSTFollistatin isoform X2. (343 aa)
GDF6Growth/differentiation factor 6. (458 aa)
ENSTTRP00000011729annotation not available (367 aa)
RBPMSRNA-binding protein with multiple splicing isoform X1. (218 aa)
CITED1Cbp/p300-interacting transactivator 1 isoform X1. (191 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (192 aa)
LATS1Serine/threonine-protein kinase LATS1. (958 aa)
GPC3Glypican-3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (597 aa)
THBS1Thrombospondin-1. (1144 aa)
CDKN2BCyclin-dependent kinase 4 inhibitor B. (86 aa)
ZNF423Zinc finger protein 423. (1278 aa)
NOTCH2Neurogenic locus notch homolog protein 2 isoform X1. (2471 aa)
GLG1Golgi apparatus protein 1. (1196 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
PMEPA1Protein TMEPAI. (289 aa)
GDF3Growth/differentiation factor 3. (364 aa)
ENSTTRP00000000710annotation not available (306 aa)
SFRP1Secreted frizzled-related protein 1 isoform X2. (307 aa)
TMPRSS6Transmembrane serine protease 6. (821 aa)
CYR61Protein CYR61. (382 aa)
TNFAIP6Tumor necrosis factor-inducible gene 6 protein isoform X2. (277 aa)
HES1Transcription factor HES-1. (280 aa)
LRG1Leucine-rich alpha-2-glycoprotein. (347 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
SKILSki-like protein isoform X1. (681 aa)
ENSTTRP00000002026annotation not available (118 aa)
FAM89BProtein FAM89B. (100 aa)
KDRVascular endothelial growth factor receptor 2 isoform X1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1307 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
TRIM33E3 ubiquitin-protein ligase TRIM33 isoform X3. (1127 aa)
WFIKKN2WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2. (574 aa)
TOB1Protein Tob1. (344 aa)
SORL1Sortilin-related receptor. (2205 aa)
ACVR1BActivin A receptor type 1B. (504 aa)
MYOCDMyocardin isoform X1. (968 aa)
BCL9LBCL9 like. (1485 aa)
SMURF1E3 ubiquitin-protein ligase. (738 aa)
SMAD3Mothers against decapentaplegic homolog 3. (291 aa)
SKOR1SKI family transcriptional corepressor 1. (960 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (234 aa)
NODALNodal homolog. (348 aa)
EP300Histone acetyltransferase p300. (2422 aa)
PRDM16PR/SET domain 16. (1217 aa)
STRAPSerine-threonine kinase receptor-associated protein isoform X1. (350 aa)
BMPERBMP-binding endothelial regulator protein. (640 aa)
INHBAInhibin beta A chain. (421 aa)
CIDEACell death activator CIDE-A isoform X2. (206 aa)
IL17Finterleukin-17F. (158 aa)
SDCBPSyntenin-1 isoform X1. (298 aa)
TFAP2BTranscription factor AP-2-beta isoform X4. (360 aa)
SPARTSpartin isoform X1. (666 aa)
HTRA3HtrA serine peptidase 3. (453 aa)
NUMA1Nuclear mitotic apparatus protein 1 isoform X1. (2113 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (475 aa)
PPARAPeroxisome proliferator-activated receptor alpha. (469 aa)
NUP93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (817 aa)
LEMD2LEM domain-containing protein 2 isoform X1. (503 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (587 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4599 aa)
LTBP1Latent-transforming growth factor beta-binding protein 1 isoform X1. (1599 aa)
DAND5DAN domain BMP antagonist family member 5. (182 aa)
IL17RDInterleukin-17 receptor D. (734 aa)
AXIN1Axin-1 isoform X2. (866 aa)
PPM1AProtein phosphatase 1A. (382 aa)
MEN1Menin 1. (615 aa)
SMURF2E3 ubiquitin-protein ligase. (648 aa)
VASNVasorin. (676 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (134 aa)
PIN1LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase NIMA-interacting 1. (162 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
ENSTTRP00000007925annotation not available (380 aa)
ASPNAsporin isoform X2. (370 aa)
PDPK13-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
CER1Cerberus. (271 aa)
GIPC1PDZ domain-containing protein GIPC1. (332 aa)
SH2B1SH2B adapter protein 1. (756 aa)
CHRDL2Chordin like 2. (452 aa)
GIPC3PDZ domain-containing protein GIPC3. (237 aa)
BMP5Bone morphogenetic protein 5 isoform X2. (454 aa)
CHST11Carbohydrate sulfotransferase. (350 aa)
ITGA3Integrin subunit alpha 3. (1068 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
RNF111E3 ubiquitin-protein ligase Arkadia isoform X11. (993 aa)
HTRA1Serine protease HTRA1. (322 aa)
CRIM1Cysteine-rich motor neuron 1 protein isoform X1. (1025 aa)
EMILIN1EMILIN-1. (994 aa)
SOX11Transcription factor SOX. (309 aa)
GDF15Growth differentiation factor 15. (308 aa)
HSPA578 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family. (654 aa)
TBX20T-box transcription factor TBX20. (449 aa)
CILPCartilage intermediate layer protein 1 isoform X2. (1182 aa)
VWC2Brorin isoform X1. (199 aa)
HJVHemojuvelin isoform X1. (426 aa)
GDF5Growth/differentiation factor 5. (489 aa)
CREBBPCREB-binding protein isoform X6. (2402 aa)
FBN2Fibrillin-2. (2776 aa)
ZNF703Zinc finger protein 703. (585 aa)
HFEHereditary hemochromatosis protein; Belongs to the MHC class I family. (348 aa)
FSTL1Follistatin-related protein 1. (306 aa)
ENGEndoglin. (655 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa)
SKOR2SKI family transcriptional corepressor 2. (296 aa)
KIAA0319Dyslexia-associated protein KIAA0319 homolog. (1011 aa)
SIRT1NAD-dependent protein deacetylase sirtuin-1 isoform X1. (616 aa)
BMP6Bone morphogenetic protein 6. (304 aa)
UBE2O(E3-independent) E2 ubiquitin-conjugating enzyme. (1293 aa)
MPP5MAGUK p55 subfamily member 5 isoform X1; Belongs to the MAGUK family. (621 aa)
RASL11BRas-like protein family member 11B. (179 aa)
NEO1Neogenin isoform X4. (1450 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
FBN1Fibrillin-1. (2826 aa)
UBL3Ubiquitin-like protein. (117 aa)
GIPC2PDZ domain-containing protein GIPC2. (312 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
CTDSPL2CTD small phosphatase-like protein 2 isoform X1. (461 aa)
SPRY1Protein sprouty homolog 1. (319 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
HIPK2Homeodomain-interacting protein kinase 2. (1185 aa)
ZC3H3Zinc finger CCCH domain-containing protein 3. (884 aa)
STK11Serine/threonine-protein kinase STK11 isoform X3. (340 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ACVRL1Activin A receptor like type 1. (497 aa)
NPNTNephronectin isoform X2. (560 aa)
ILKIntegrin-linked protein kinase. (450 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SNX25Sorting nexin-25 isoform X1. (834 aa)
SFRP2Secreted frizzled-related protein 2. (294 aa)
NBL1Neuroblastoma suppressor of tumorigenicity 1 isoform X2. (211 aa)
TWSG1Twisted gastrulation protein homolog 1. (223 aa)
ENSTTRP00000013860annotation not available (807 aa)
LOC101331122Kielin/chordin-like protein. (254 aa)
VEPH1Ventricular zone-expressed PH domain-containing protein homolog 1. (831 aa)
LOC101327238Left-right determination factor. (201 aa)
CD109CD109 antigen isoform X1. (1440 aa)
ADAMTSL2ADAMTS-like protein 2. (1020 aa)
INHBBInhibin beta B chain. (407 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
RNF165RING finger protein 165. (308 aa)
TGFBR3Transforming growth factor beta receptor type 3 isoform X4. (848 aa)
NRROSNegative regulator of reactive oxygen species isoform X2. (692 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (458 aa)
CITED2Cbp/p300-interacting transactivator 2. (272 aa)
FLCNFolliculin isoform X2. (574 aa)
LOXLysyl oxidase. (411 aa)
VWC2LVon Willebrand factor C domain-containing protein 2-like. (137 aa)
DLX6Homeobox protein DLX-6. (232 aa)
NOTCH1Neurogenic locus notch homolog protein 1. (2527 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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