(33 nodes) Positive regulation of miRNA transcription network (Tursiops truncatus)

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	BMPR1A	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
	PDGFB	Platelet-derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (240 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (574 aa)
	NR1H2	Oxysterols receptor LXR-beta isoform X1. (446 aa)
	BMP2	Bone morphogenetic protein 2. (388 aa)
	MYOCD	Myocardin isoform X1. (968 aa)
	SMAD3	Mothers against decapentaplegic homolog 3. (291 aa)
	TERT	Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1124 aa)
	KLF5	Krueppel-like factor 5. (370 aa)
	GATA3	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1. (444 aa)
	EGR1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (509 aa)
	TEAD1	Transcriptional enhancer factor TEF-1 isoform X4. (426 aa)
	MRTFB	MKL/myocardin-like protein 2 isoform X3. (969 aa)
	SRF	Serum response factor isoform X2. (509 aa)
	STAT3	Signal transducer and activator of transcription. (767 aa)
	NGFR	Tumor necrosis factor receptor superfamily member 16. (427 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	GNL3	Guanine nucleotide-binding protein-like 3 isoform X2. (341 aa)
	BMP4	Bone morphogenetic protein 4. (407 aa)
	SMARCA4	Transcription activator BRG1. (1644 aa)
	SMAD6	SMAD family member 6. (492 aa)
	ETS1	Protein C-ets-1. (485 aa)
	ATOH8	Protein atonal homolog 8. (411 aa)
	MRTFA	Phosphatase and actin regulator. (925 aa)
	JUN	Transcription factor AP-1; Belongs to the bZIP family. (321 aa)
	SMAD4	Mothers against decapentaplegic homolog. (407 aa)
	HIF1A	Hypoxia-inducible factor 1-alpha isoform X1. (824 aa)
	WT1	Wilms tumor protein isoform X2. (336 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa)
	FOSL1	Fos-related antigen 1. (271 aa)
	FOXO3	Forkhead box protein O3. (612 aa)
	SREBF2	Sterol regulatory element-binding protein 2. (1029 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP2	BMP4	ENSTTRP00000002383	ENSTTRP00000008787	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.899
BMP2	BMPR1A	ENSTTRP00000002383	ENSTTRP00000007678	Bone morphogenetic protein 2.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.999
BMP2	SMAD1	ENSTTRP00000002383	ENSTTRP00000007646	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.837
BMP2	SMAD3	ENSTTRP00000002383	ENSTTRP00000002846	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog 3.	0.663
BMP2	SMAD4	ENSTTRP00000002383	ENSTTRP00000011160	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.874
BMP2	SMAD6	ENSTTRP00000002383	ENSTTRP00000009705	Bone morphogenetic protein 2.	SMAD family member 6.	0.789
BMP2	TGFB2	ENSTTRP00000002383	ENSTTRP00000012883	Bone morphogenetic protein 2.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.431
BMP4	BMP2	ENSTTRP00000008787	ENSTTRP00000002383	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.899
BMP4	BMPR1A	ENSTTRP00000008787	ENSTTRP00000007678	Bone morphogenetic protein 4.	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	0.995
BMP4	GATA3	ENSTTRP00000008787	ENSTTRP00000004761	Bone morphogenetic protein 4.	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	0.403
BMP4	SMAD1	ENSTTRP00000008787	ENSTTRP00000007646	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.791
BMP4	SMAD3	ENSTTRP00000008787	ENSTTRP00000002846	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog 3.	0.749
BMP4	SMAD4	ENSTTRP00000008787	ENSTTRP00000011160	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.913
BMP4	SMAD6	ENSTTRP00000008787	ENSTTRP00000009705	Bone morphogenetic protein 4.	SMAD family member 6.	0.810
BMP4	STAT3	ENSTTRP00000008787	ENSTTRP00000006780	Bone morphogenetic protein 4.	Signal transducer and activator of transcription.	0.495
BMP4	WT1	ENSTTRP00000008787	ENSTTRP00000012161	Bone morphogenetic protein 4.	Wilms tumor protein isoform X2.	0.419
BMPR1A	BMP2	ENSTTRP00000007678	ENSTTRP00000002383	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 2.	0.999
BMPR1A	BMP4	ENSTTRP00000007678	ENSTTRP00000008787	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Bone morphogenetic protein 4.	0.995
BMPR1A	GATA3	ENSTTRP00000007678	ENSTTRP00000004761	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Trans-acting T-cell-specific transcription factor GATA-3 isoform X1.	0.548
BMPR1A	SMAD1	ENSTTRP00000007678	ENSTTRP00000007646	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.	Mothers against decapentaplegic homolog.	0.946