STRINGSTRING
PIWIL4 PIWIL4 EXD1 EXD1 TOE1 TOE1 PAN2 PAN2 ERI1 ERI1 KRBA2 KRBA2 POLA1 POLA1 TEFM TEFM PARN PARN POLQ POLQ EXOSC10 EXOSC10 GIN1 GIN1 ESRP1 ESRP1 PIWIL1 PIWIL1 REXO5 REXO5 ERI2 ERI2 CNOT8 CNOT8 ZBED9 ZBED9 AGO3 AGO3 AGO1 AGO1 AGO4 AGO4 REXO2 REXO2 REV3L REV3L ISG20L2 ISG20L2 PIWIL2 PIWIL2 NYNRIN NYNRIN CNOT7 CNOT7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIWIL4Piwi-like protein 4; Belongs to the argonaute family. (850 aa)
EXD1piRNA biogenesis protein EXD1. (512 aa)
TOE1Target of EGR1 protein 1 isoform X1. (509 aa)
PAN2PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...] (1199 aa)
ERI13'-5' exoribonuclease 1. (349 aa)
KRBA2KRAB-A domain-containing protein 2. (491 aa)
POLA1DNA polymerase. (1467 aa)
TEFMTranscription elongation factor, mitochondrial isoform X2. (360 aa)
PARNpoly(A)-specific ribonuclease PARN isoform X2. (627 aa)
POLQDNA polymerase theta. (2722 aa)
EXOSC10Exosome component 10 isoform X2. (886 aa)
GIN1Gypsy retrotransposon integrase-like protein 1 isoform X2. (522 aa)
ESRP1Epithelial splicing regulatory protein 1 isoform X2. (675 aa)
PIWIL1Piwi-like protein 1; Belongs to the argonaute family. (861 aa)
REXO5Putative RNA exonuclease NEF-sp isoform X1. (774 aa)
ERI2ERI1 exoribonuclease 2 isoform X1. (680 aa)
CNOT8CCR4-NOT transcription complex subunit 8 isoform X1. (292 aa)
ZBED9SCAN domain-containing protein 3. (1326 aa)
AGO3Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (853 aa)
AGO1Protein argonaute-1 isoform X1; Belongs to the argonaute family. (854 aa)
AGO4Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (854 aa)
REXO2Oligoribonuclease, mitochondrial. (237 aa)
REV3LDNA polymerase zeta catalytic subunit isoform X1. (3122 aa)
ISG20L2Interferon-stimulated 20 kDa exonuclease-like 2. (344 aa)
PIWIL2Piwi-like protein 2 isoform X1; Belongs to the argonaute family. (964 aa)
NYNRINProtein NYNRIN. (484 aa)
CNOT7CCR4-NOT transcription complex subunit 7. (285 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.