STRINGSTRING
SEPTIN3 SEPTIN3 TUBD1 TUBD1 ARL1 ARL1 RHEB RHEB DNM3 DNM3 SAR1B SAR1B DNM2 DNM2 RHOF RHOF RHOT1 RHOT1 AK4 AK4 TUBG1 TUBG1 SEPTIN7 SEPTIN7 GUF1 GUF1 RHOBTB1 RHOBTB1 SRP54 SRP54 TUBA4A TUBA4A RP2 RP2 ATL1 ATL1 GNA13 GNA13 LOC101330624 LOC101330624 GNAQ GNAQ GNL2 GNL2 RASL11A RASL11A ARL5B ARL5B GNAT1 GNAT1 ARL16 ARL16 SUCLG2 SUCLG2 RASD2 RASD2 ARL13B ARL13B RAB21 RAB21 DIRAS2 DIRAS2 IFT27 IFT27 SAR1A SAR1A TRIM23 TRIM23 RAP2B RAP2B GNAI1 GNAI1 RAP2C RAP2C THG1L THG1L RTCB RTCB MRAS MRAS TUBB2B TUBB2B ATL2 ATL2 RND3 RND3 ARF5 ARF5 RASL12 RASL12 REM1 REM1 CDC42 CDC42 RHOB RHOB ARL13A ARL13A SEPTIN12 SEPTIN12 ARL10 ARL10 GFM2 GFM2 RAP1A RAP1A TUBB1-2 TUBB1-2 RAC1 RAC1 TUBA1B TUBA1B RHEBL1 RHEBL1 ARF3 ARF3 RND1 RND1 GBP2 GBP2 LOC101337451 LOC101337451 TUBE1 TUBE1 GNA12 GNA12 TUBB6 TUBB6 ARF6 ARF6 ARL15 ARL15 OPA1 OPA1 RHOU RHOU RHOH RHOH DIRAS3 DIRAS3 SEPTIN8 SEPTIN8 RALB RALB ADSS ADSS RHOJ RHOJ TUFM TUFM GFM1 GFM1 SEPT14 SEPT14 ARL6 ARL6 RAC3 RAC3 GNAT2 GNAT2 RAC2 RAC2 MX1 MX1 RRAD RRAD GNAS GNAS MTG1 MTG1 RASL11B RASL11B GBP6 GBP6 RAP1B RAP1B ARL5A ARL5A RERG RERG SEPTIN2 SEPTIN2 RRAS2 RRAS2 GBP1 GBP1 RALA RALA ARL9 ARL9 RERGL RERGL HRAS HRAS RHOV RHOV GNA14 GNA14 RASL10A RASL10A RHOQ RHOQ ARFRP1 ARFRP1 GEM GEM ARL4A ARL4A KRAS KRAS ARL3 ARL3 RAN RAN SEPTIN6 SEPTIN6 RIT1 RIT1 ATL3 ATL3 RASD1 RASD1 SEPTIN11 SEPTIN11 TUBAL3 TUBAL3 ARL8B ARL8B GNAT3 GNAT3 ADSS1 ADSS1 ARF1 ARF1 RASL10B RASL10B RNGTT RNGTT DNM1L DNM1L RHOA RHOA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SEPTIN3Neuronal-specific septin-3 isoform X4; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
TUBD1Tubulin delta chain isoform X1; Belongs to the tubulin family. (454 aa)
ARL1ADP-ribosylation factor-like protein 1; Belongs to the small GTPase superfamily. Arf family. (191 aa)
RHEBGTP-binding protein Rheb. (166 aa)
DNM3Dynamin-3 isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (814 aa)
SAR1BGTP-binding protein SAR1b; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
DNM2Dynamin-2 isoform X4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (871 aa)
RHOFRho-related GTP-binding protein RhoF. (211 aa)
RHOT1Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (691 aa)
AK4Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (223 aa)
TUBG1Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (451 aa)
SEPTIN7Septin-7 isoform X6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (415 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (669 aa)
RHOBTB1Rho-related BTB domain-containing protein 1 isoform X1. (698 aa)
SRP54Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Belongs to the GTP-binding SRP family. SRP54 subfamily. (504 aa)
TUBA4ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (369 aa)
RP2Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization. (350 aa)
ATL1Atlastin-1 isoform X1. (558 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (282 aa)
LOC101330624Tubulin beta chain-like isoform X2; Belongs to the tubulin family. (346 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (732 aa)
RASL11ARas-like protein family member 11A isoform X1. (242 aa)
ARL5BADP-ribosylation factor-like protein 5B; Belongs to the small GTPase superfamily. Arf family. (179 aa)
GNAT1Guanine nucleotide-binding protein G(T) subunit alpha-1. (350 aa)
ARL16LOW QUALITY PROTEIN: ADP-ribosylation factor-like protein 16. (190 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (432 aa)
RASD2GTP-binding protein Rhes isoform X1. (266 aa)
ARL13BADP-ribosylation factor-like protein 13B. (410 aa)
RAB21Ras-related protein Rab-21. (125 aa)
DIRAS2GTP-binding protein Di-Ras2. (199 aa)
IFT27Intraflagellar transport protein 27 homolog isoform X1. (276 aa)
SAR1AGTP-binding protein SAR1a; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
TRIM23E3 ubiquitin-protein ligase TRIM23 isoform X1. (574 aa)
RAP2BRas-related protein Rap-2b. (183 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
RAP2CRas-related protein Rap-2c. (183 aa)
THG1LtRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (298 aa)
RTCBRNA-splicing ligase RtcB homolog; Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs. (470 aa)
MRASRas-related protein M-Ras. (175 aa)
TUBB2BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
ATL2Atlastin-2 isoform X1. (583 aa)
RND3Rho-related GTP-binding protein RhoE. (244 aa)
ARF5ADP-ribosylation factor 5; Belongs to the small GTPase superfamily. Arf family. (162 aa)
RASL12Ras-like protein family member 12. (264 aa)
REM1GTP-binding protein REM 1. (298 aa)
CDC42Cell division control protein 42 homolog. (156 aa)
RHOBRho-related GTP-binding protein RhoB. (196 aa)
ARL13AADP-ribosylation factor-like protein 13A. (297 aa)
SEPTIN12Septin-12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (376 aa)
ARL10ADP-ribosylation factor-like protein 10. (244 aa)
GFM2Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (776 aa)
RAP1ARas-related protein Rap-1A isoform X1. (184 aa)
TUBB1-2Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. Belongs to the tubulin family. (774 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (199 aa)
TUBA1BTubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (450 aa)
RHEBL1GTPase RhebL1 isoform X2. (183 aa)
ARF3ADP-ribosylation factor 3 isoform X1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
RND1Rho-related GTP-binding protein Rho6. (231 aa)
GBP2LOW QUALITY PROTEIN: guanylate-binding protein 2-like. (548 aa)
LOC101337451Guanylate-binding protein 4. (628 aa)
TUBE1Tubulin epsilon chain; Belongs to the tubulin family. (475 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (382 aa)
TUBB6Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (426 aa)
ARF6ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (201 aa)
ARL15ADP-ribosylation factor-like protein 15 isoform X3. (169 aa)
OPA1Dynamin-like 120 kDa protein, mitochondrial isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (1015 aa)
RHOURho-related GTP-binding protein RhoU. (170 aa)
RHOHRho-related GTP-binding protein RhoH. (191 aa)
DIRAS3GTP-binding protein Di-Ras3. (230 aa)
SEPTIN8Septin-6 isoform X5; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (472 aa)
RALBRas-related protein Ral-B isoform X2. (202 aa)
ADSSAdenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. (456 aa)
RHOJRho-related GTP-binding protein RhoJ. (214 aa)
TUFMElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (275 aa)
GFM1Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mito [...] (755 aa)
SEPT14Septin-14 isoform X2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (373 aa)
ARL6ADP-ribosylation factor-like protein 6; Belongs to the small GTPase superfamily. Arf family. (186 aa)
RAC3Ras-related C3 botulinum toxin substrate 1 isoform X2. (192 aa)
GNAT2Guanine nucleotide-binding protein G(T) subunit alpha-2. (354 aa)
RAC2Ras-related C3 botulinum toxin substrate 1. (192 aa)
MX1LOW QUALITY PROTEIN: interferon-induced GTP-binding protein Mx1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (496 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
MTG1Mitochondrial GTPase 1; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (331 aa)
RASL11BRas-like protein family member 11B. (179 aa)
GBP6Guanylate-binding protein 6. (632 aa)
RAP1BRas-related protein Rap-1b. (184 aa)
ARL5AADP-ribosylation factor-like protein 5A isoform X1; Belongs to the small GTPase superfamily. Arf family. (179 aa)
RERGRas-related and estrogen-regulated growth inhibitor isoform X4. (199 aa)
SEPTIN2Septin-2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (372 aa)
RRAS2Ras-related protein R-Ras2 isoform X2. (204 aa)
GBP1Guanylate-binding protein 1-like. (552 aa)
RALARas-related protein Ral-A isoform X1. (206 aa)
ARL9ADP-ribosylation factor-like protein 9; Belongs to the small GTPase superfamily. Arf family. (195 aa)
RERGLRas-related and estrogen-regulated growth inhibitor-like protein. (186 aa)
HRASGTPase HRas isoform X1. (189 aa)
RHOVRho-related GTP-binding protein RhoV. (236 aa)
GNA14Guanine nucleotide-binding protein subunit alpha-14. (328 aa)
RASL10ARas-like protein family member 10A. (202 aa)
RHOQRho-related GTP-binding protein RhoQ. (138 aa)
ARFRP1ADP-ribosylation factor-related protein 1 isoform X1. (201 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
ARL4ALOW QUALITY PROTEIN: ADP-ribosylation factor-like protein 4A. (200 aa)
KRASGTPase KRas. (189 aa)
ARL3ADP-ribosylation factor-like protein 3; Belongs to the small GTPase superfamily. Arf family. (181 aa)
RANGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (231 aa)
SEPTIN6Septin-6 isoform X2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (495 aa)
RIT1GTP-binding protein Rit1. (232 aa)
ATL3Atlastin-3 isoform X1. (565 aa)
RASD1Dexamethasone-induced Ras-related protein 1. (276 aa)
SEPTIN11Septin-11 isoform X1; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (429 aa)
TUBAL3Tubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (445 aa)
ARL8BLOW QUALITY PROTEIN: ADP-ribosylation factor-like protein 8B; Belongs to the small GTPase superfamily. Arf family. (186 aa)
GNAT3LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(T) subunit alpha-3-like. (302 aa)
ADSS1Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (391 aa)
ARF1ADP-ribosylation factor 2 isoform X1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
RASL10BRas-like protein family member 10B isoform X2. (131 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (574 aa)
DNM1LDynamin-1-like protein isoform X2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (746 aa)
RHOATransforming protein RhoA. (193 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.