(49 nodes) Elastic fibre formation network (Tursiops truncatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	EFEMP1	EGF-containing fibulin-like extracellular matrix protein 1 isoform X1. (489 aa)
	GDF5	Growth/differentiation factor 5. (489 aa)
	FBN2	Fibrillin-2. (2776 aa)
	HHIPL1	HHIP-like protein 1. (561 aa)
	EFEMP2	EGF containing fibulin extracellular matrix protein 2. (443 aa)
	HHIPL2	LOW QUALITY PROTEIN: HHIP-like protein 2. (405 aa)
	BMP6	Bone morphogenetic protein 6. (304 aa)
	BMP7	Bone morphogenetic protein 7 isoform X2. (431 aa)
	FBN1	Fibrillin-1. (2826 aa)
	MFAP2	Microfibrillar-associated protein 2. (183 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
	ITGB8	Integrin beta; Belongs to the integrin beta chain family. (765 aa)
	ITGB5	Integrin beta; Belongs to the integrin beta chain family. (782 aa)
	PCSK4	Proprotein convertase subtilisin/kexin type 4. (758 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
	BMP10	Bone morphogenetic protein 10. (423 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (783 aa)
	LTBP2	Latent transforming growth factor beta binding protein 2. (1814 aa)
	TGFB1	Transforming growth factor beta 1. (338 aa)
	LOXL3	Lysyl oxidase homolog 3 isoform X2. (752 aa)
	ITGAV	Integrin alpha-V isoform X1; Belongs to the integrin alpha chain family. (1095 aa)
	GDF6	Growth/differentiation factor 6. (458 aa)
	LOXL2	Lysyl oxidase homolog 2. (771 aa)
	FBLN2	Fibulin 2. (1213 aa)
	ITGB6	Integrin beta; Belongs to the integrin beta chain family. (788 aa)
	MFAP3L	Microfibrillar-associated protein 3-like. (406 aa)
	MFAP4	Microfibril associated protein 4. (272 aa)
	VTN	Vitronectin. (480 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (786 aa)
	BMP4	Bone morphogenetic protein 4. (407 aa)
	ELN	Elastin. (728 aa)
	EMILIN2	EMILIN-2. (1042 aa)
	FBLN5	Fibulin-5. (500 aa)
	FURIN	Furin; Belongs to the peptidase S8 family. (792 aa)
	LOX	Lysyl oxidase. (411 aa)
	LTBP4	Latent transforming growth factor beta binding protein 4. (1624 aa)
	LTBP1	Latent-transforming growth factor beta-binding protein 1 isoform X1. (1599 aa)
	LOXL4	Lysyl oxidase homolog 4. (755 aa)
	BMP5	Bone morphogenetic protein 5 isoform X2. (454 aa)
	EMILIN1	EMILIN-1. (994 aa)
	MFAP3	Microfibril-associated glycoprotein 3. (361 aa)
	ITGA8	Integrin alpha-8; Belongs to the integrin alpha chain family. (1060 aa)
	EMILIN3	EMILIN-3. (676 aa)
	BMP2	Bone morphogenetic protein 2. (388 aa)
	LTBP3	Latent transforming growth factor beta binding protein 3. (1301 aa)
	FBN3	Fibrillin 3. (2775 aa)
	FBLN1	Fibulin-1 isoform X1. (724 aa)
	MFAP5	Microfibrillar-associated protein 5. (169 aa)
	LOXL1	Lysyl oxidase homolog 1. (584 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP10	BMP2	ENSTTRP00000012877	ENSTTRP00000002383	Bone morphogenetic protein 10.	Bone morphogenetic protein 2.	0.417
BMP10	BMP4	ENSTTRP00000012877	ENSTTRP00000008787	Bone morphogenetic protein 10.	Bone morphogenetic protein 4.	0.630
BMP10	BMP5	ENSTTRP00000012877	ENSTTRP00000005374	Bone morphogenetic protein 10.	Bone morphogenetic protein 5 isoform X2.	0.653
BMP10	BMP7	ENSTTRP00000012877	ENSTTRP00000014836	Bone morphogenetic protein 10.	Bone morphogenetic protein 7 isoform X2.	0.423
BMP10	GDF5	ENSTTRP00000012877	ENSTTRP00000016136	Bone morphogenetic protein 10.	Growth/differentiation factor 5.	0.406
BMP2	BMP10	ENSTTRP00000002383	ENSTTRP00000012877	Bone morphogenetic protein 2.	Bone morphogenetic protein 10.	0.417
BMP2	BMP4	ENSTTRP00000002383	ENSTTRP00000008787	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.899
BMP2	BMP5	ENSTTRP00000002383	ENSTTRP00000005374	Bone morphogenetic protein 2.	Bone morphogenetic protein 5 isoform X2.	0.616
BMP2	BMP6	ENSTTRP00000002383	ENSTTRP00000015103	Bone morphogenetic protein 2.	Bone morphogenetic protein 6.	0.938
BMP2	BMP7	ENSTTRP00000002383	ENSTTRP00000014836	Bone morphogenetic protein 2.	Bone morphogenetic protein 7 isoform X2.	0.719
BMP2	GDF5	ENSTTRP00000002383	ENSTTRP00000016136	Bone morphogenetic protein 2.	Growth/differentiation factor 5.	0.543
BMP2	GDF6	ENSTTRP00000002383	ENSTTRP00000011723	Bone morphogenetic protein 2.	Growth/differentiation factor 6.	0.435
BMP2	ITGB1	ENSTTRP00000002383	ENSTTRP00000009434	Bone morphogenetic protein 2.	Integrin beta; Belongs to the integrin beta chain family.	0.599
BMP2	TGFB1	ENSTTRP00000002383	ENSTTRP00000012180	Bone morphogenetic protein 2.	Transforming growth factor beta 1.	0.504
BMP2	TGFB2	ENSTTRP00000002383	ENSTTRP00000012883	Bone morphogenetic protein 2.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.431
BMP4	BMP10	ENSTTRP00000008787	ENSTTRP00000012877	Bone morphogenetic protein 4.	Bone morphogenetic protein 10.	0.630
BMP4	BMP2	ENSTTRP00000008787	ENSTTRP00000002383	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.899
BMP4	BMP5	ENSTTRP00000008787	ENSTTRP00000005374	Bone morphogenetic protein 4.	Bone morphogenetic protein 5 isoform X2.	0.739
BMP4	BMP6	ENSTTRP00000008787	ENSTTRP00000015103	Bone morphogenetic protein 4.	Bone morphogenetic protein 6.	0.955
BMP4	BMP7	ENSTTRP00000008787	ENSTTRP00000014836	Bone morphogenetic protein 4.	Bone morphogenetic protein 7 isoform X2.	0.863