(55 nodes) AUF1 (hnRNP D0) binds and destabilizes mRNA network (Tursiops truncatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	PSMB11	Proteasome subunit beta. (259 aa)
	PSMD10	26S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
	PSME3	Proteasome activator subunit 3. (268 aa)
	PSMB7	Proteasome subunit beta. (277 aa)
	PSMA3	Proteasome subunit alpha type. (255 aa)
	PSMD13	26S proteasome non-ATPase regulatory subunit 13. (376 aa)
	PSMC1	26S protease regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
	PSMD6	26S proteasome non-ATPase regulatory subunit 6 isoform X1. (389 aa)
	RPS27A	ubiquitin-40S ribosomal protein S27a. (156 aa)
	PSMD12	26S proteasome non-ATPase regulatory subunit 12 isoform X2. (455 aa)
	PSMD7	26S proteasome non-ATPase regulatory subunit 7 isoform X2. (322 aa)
	HSPA6	LOW QUALITY PROTEIN: heat shock 70 kDa protein 6; Belongs to the heat shock protein 70 family. (641 aa)
	PSMC3	26S protease regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (433 aa)
	PSMD14	26S proteasome non-ATPase regulatory subunit 14. (294 aa)
	PSMD5	26S proteasome non-ATPase regulatory subunit 5 isoform X1. (504 aa)
	PSMB3	Proteasome subunit beta. (205 aa)
	PSMC5	26S protease regulatory subunit 8 isoform X3; Belongs to the AAA ATPase family. (406 aa)
	PSMD4	26S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
	PSMB2	Proteasome subunit beta. (248 aa)
	PSME4	Proteasome activator complex subunit 4 isoform X2. (1762 aa)
	HNRNPD	Heterogeneous nuclear ribonucleoprotein D0 isoform X1. (355 aa)
	PABPC1L	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (585 aa)
	PSMD3	26S proteasome non-ATPase regulatory subunit 3. (534 aa)
	PSMD1	26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (949 aa)
	PSMB1	Proteasome subunit beta. (239 aa)
	PSMA8	Proteasome subunit alpha type. (221 aa)
	PABPC4	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (555 aa)
	PSMA5	Proteasome subunit alpha type. (241 aa)
	PSMB10	Proteasome 20S subunit beta 10. (273 aa)
	UBB	polyubiquitin-B. (229 aa)
	PSME2	Proteasome activator complex subunit 2. (248 aa)
	PSME1	Proteasome activator complex subunit 1. (248 aa)
	PSMA6	Proteasome subunit alpha type. (246 aa)
	PSMB4	Proteasome 20S subunit beta 4. (259 aa)
	EIF4G1	Eukaryotic translation initiation factor 4 gamma 1. (1537 aa)
	PSMD11	26S proteasome non-ATPase regulatory subunit 11. (422 aa)
	HSPA8	Heat shock cognate 71 kDa protein. (650 aa)
	PSMA7	Proteasome subunit alpha type. (248 aa)
	PSMC2	26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
	PSMD8	26S proteasome non-ATPase regulatory subunit 8. (351 aa)
	HNRNPAB	Heterogeneous nuclear ribonucleoprotein A/B isoform X3. (299 aa)
	PSMF1	Proteasome inhibitor PI31 subunit isoform X1. (256 aa)
	PSMA2	Proteasome subunit alpha type. (234 aa)
	PABPC1	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (620 aa)
	PSMB9	Proteasome subunit beta. (219 aa)
	PSMB8	Proteasome subunit beta. (247 aa)
	PSMC6	26S protease regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (389 aa)
	PSMA1	Proteasome subunit alpha type. (269 aa)
	PSMD9	26S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
	UBC	polyubiquitin-C. (457 aa)
	PSMB5	Proteasome subunit beta. (215 aa)
	PSMC4	26S protease regulatory subunit 6B isoform X2; Belongs to the AAA ATPase family. (416 aa)
	PSMA4	Proteasome subunit alpha type. (258 aa)
	PSMB6	Proteasome subunit beta type-6. (238 aa)
	UBA52	ubiquitin-60S ribosomal protein L40. (128 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EIF4G1	HNRNPAB	ENSTTRP00000010666	ENSTTRP00000010055	Eukaryotic translation initiation factor 4 gamma 1.	Heterogeneous nuclear ribonucleoprotein A/B isoform X3.	0.584
EIF4G1	HNRNPD	ENSTTRP00000010666	ENSTTRP00000007180	Eukaryotic translation initiation factor 4 gamma 1.	Heterogeneous nuclear ribonucleoprotein D0 isoform X1.	0.616
EIF4G1	HSPA6	ENSTTRP00000010666	ENSTTRP00000013406	Eukaryotic translation initiation factor 4 gamma 1.	LOW QUALITY PROTEIN: heat shock 70 kDa protein 6; Belongs to the heat shock protein 70 family.	0.942
EIF4G1	HSPA8	ENSTTRP00000010666	ENSTTRP00000010561	Eukaryotic translation initiation factor 4 gamma 1.	Heat shock cognate 71 kDa protein.	0.974
EIF4G1	PABPC1	ENSTTRP00000010666	ENSTTRP00000004419	Eukaryotic translation initiation factor 4 gamma 1.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.989
EIF4G1	PABPC1L	ENSTTRP00000010666	ENSTTRP00000007204	Eukaryotic translation initiation factor 4 gamma 1.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.944
EIF4G1	PABPC4	ENSTTRP00000010666	ENSTTRP00000013598	Eukaryotic translation initiation factor 4 gamma 1.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.951
EIF4G1	RPS27A	ENSTTRP00000010666	ENSTTRP00000013220	Eukaryotic translation initiation factor 4 gamma 1.	ubiquitin-40S ribosomal protein S27a.	0.735
EIF4G1	UBB	ENSTTRP00000010666	ENSTTRP00000008479	Eukaryotic translation initiation factor 4 gamma 1.	polyubiquitin-B.	0.573
EIF4G1	UBC	ENSTTRP00000010666	ENSTTRP00000001552	Eukaryotic translation initiation factor 4 gamma 1.	polyubiquitin-C.	0.573
HNRNPAB	EIF4G1	ENSTTRP00000010055	ENSTTRP00000010666	Heterogeneous nuclear ribonucleoprotein A/B isoform X3.	Eukaryotic translation initiation factor 4 gamma 1.	0.584
HNRNPAB	HSPA6	ENSTTRP00000010055	ENSTTRP00000013406	Heterogeneous nuclear ribonucleoprotein A/B isoform X3.	LOW QUALITY PROTEIN: heat shock 70 kDa protein 6; Belongs to the heat shock protein 70 family.	0.549
HNRNPAB	HSPA8	ENSTTRP00000010055	ENSTTRP00000010561	Heterogeneous nuclear ribonucleoprotein A/B isoform X3.	Heat shock cognate 71 kDa protein.	0.644
HNRNPAB	PABPC1	ENSTTRP00000010055	ENSTTRP00000004419	Heterogeneous nuclear ribonucleoprotein A/B isoform X3.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.619
HNRNPAB	PABPC1L	ENSTTRP00000010055	ENSTTRP00000007204	Heterogeneous nuclear ribonucleoprotein A/B isoform X3.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.500
HNRNPAB	PABPC4	ENSTTRP00000010055	ENSTTRP00000013598	Heterogeneous nuclear ribonucleoprotein A/B isoform X3.	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family.	0.500
HNRNPAB	PSMA1	ENSTTRP00000010055	ENSTTRP00000003409	Heterogeneous nuclear ribonucleoprotein A/B isoform X3.	Proteasome subunit alpha type.	0.408
HNRNPAB	PSMA5	ENSTTRP00000010055	ENSTTRP00000009061	Heterogeneous nuclear ribonucleoprotein A/B isoform X3.	Proteasome subunit alpha type.	0.404
HNRNPAB	PSMA7	ENSTTRP00000010055	ENSTTRP00000010473	Heterogeneous nuclear ribonucleoprotein A/B isoform X3.	Proteasome subunit alpha type.	0.417
HNRNPAB	PSMB2	ENSTTRP00000010055	ENSTTRP00000006870	Heterogeneous nuclear ribonucleoprotein A/B isoform X3.	Proteasome subunit beta.	0.429