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ENSTTRP00000015893 ENSTTRP00000015893 LOC101330510 LOC101330510 PSMB6 PSMB6 PSMA4 PSMA4 PSMC4 PSMC4 PRIM2 PRIM2 POLE3 POLE3 RPA1 RPA1 PSMB5 PSMB5 UBC UBC ANAPC2 ANAPC2 PRIM1 PRIM1 FAM89B FAM89B UBE2S UBE2S UBE2E1 UBE2E1 TM7SF3 TM7SF3 H2BC1 H2BC1 ANAPC4 ANAPC4 PSMD9 PSMD9 CDC26 CDC26 PSMA1 PSMA1 MCM6 MCM6 MCM3 MCM3 PSMC6 PSMC6 PSMB8 PSMB8 PSMB9 PSMB9 CDT1 CDT1 KPNB1 KPNB1 H2BC18 H2BC18 LOC101320102 LOC101320102 ENSTTRP00000004809 ENSTTRP00000004809 ENSTTRP00000004818 ENSTTRP00000004818 LOC101322350 LOC101322350 H2AC20 H2AC20 POLA1 POLA1 CDC23 CDC23 PSMA2 PSMA2 CDC7 CDC7 H2BU1 H2BU1 DBF4 DBF4 PSMD14 PSMD14 PSMD5 PSMD5 PSMB3 PSMB3 H2AZ2 H2AZ2 PSMC5 PSMC5 PSMD4 PSMD4 PSMB2 PSMB2 MCM5 MCM5 H2AJ H2AJ ENSTTRP00000006970 ENSTTRP00000006970 RPA2 RPA2 POLE2 POLE2 PSMA6 PSMA6 MCM4 MCM4 PSME1 PSME1 PSME2 PSME2 FZR1 FZR1 ORC3 ORC3 UBB UBB UBE2D1 UBE2D1 PSMB10 PSMB10 PSMA5 PSMA5 KPNA6 KPNA6 ANAPC16 ANAPC16 PSMD10 PSMD10 POLE4 POLE4 PSMF1 PSMF1 KXD1 KXD1 PSMD8 PSMD8 POLE POLE PSMC2 PSMC2 ORC5 ORC5 ANAPC15 ANAPC15 KPNA5 KPNA5 PSMA7 PSMA7 MCM10 MCM10 PSMD11 PSMD11 MEIOB MEIOB PSMB4 PSMB4 PSME3 PSME3 ORC2 ORC2 CREBZF CREBZF ANAPC10 ANAPC10 ANAPC11 ANAPC11 MCM7 MCM7 TM4SF19 TM4SF19 MCM8 MCM8 PSMB7 PSMB7 ORC6 ORC6 KPNA1 KPNA1 LOC101322612 LOC101322612 LOC101330510-2 LOC101330510-2 LOC101320102-2 LOC101320102-2 LOC101329634 LOC101329634 LOC101329341 LOC101329341 H2BC15 H2BC15 LOC101322612-2 LOC101322612-2 LOC101320102-3 LOC101320102-3 LOC101322612-3 LOC101322612-3 LOC101328760 LOC101328760 PSMA3 PSMA3 PSMD13 PSMD13 CDC27 CDC27 PSMC1 PSMC1 PSMD6 PSMD6 RPA3 RPA3 RPS27A RPS27A PSMD12 PSMD12 MCM9 MCM9 PSMD7 PSMD7 PSMC3 PSMC3 ANAPC5 ANAPC5 PSMB1 PSMB1 CDC45 CDC45 CDK2 CDK2 H2AZ1 H2AZ1 ANAPC7 ANAPC7 CDC16 CDC16 H2BC11 H2BC11 LOC101320102-4 LOC101320102-4 LOC101319223 LOC101319223 CDK3 CDK3 UBE2C UBE2C PSMD1 PSMD1 GMNN GMNN ORC1 ORC1 ORC4 ORC4 ANAPC1 ANAPC1 LOC101322612-4 LOC101322612-4 ENSTTRP00000015863 ENSTTRP00000015863 LOC101320102-5 LOC101320102-5 LOC101322612-5 LOC101322612-5 ENSTTRP00000015867 ENSTTRP00000015867 H2BC3 H2BC3 LOC101322612-6 LOC101322612-6 LOC101320102-6 LOC101320102-6 LOC101328661 LOC101328661 LOC101327496 LOC101327496 LOC101320102-7 LOC101320102-7 LOC101332610 LOC101332610 LOC101321474 LOC101321474 LOC101322612-7 LOC101322612-7 LOC101320102-8 LOC101320102-8 LOC101322612-8 LOC101322612-8 LOC101324906 LOC101324906 LOC101322612-9 LOC101322612-9 LOC101323719 LOC101323719 LOC101320102-9 LOC101320102-9 PSMD3 PSMD3 CDC6 CDC6 MCM2 MCM2 LOC101316193 LOC101316193 UBA52 UBA52
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSTTRP00000015893annotation not available (99 aa)
LOC101330510Histone H2B; Belongs to the histone H2B family. (126 aa)
PSMB6Proteasome subunit beta type-6. (238 aa)
PSMA4Proteasome subunit alpha type. (258 aa)
PSMC426S protease regulatory subunit 6B isoform X2; Belongs to the AAA ATPase family. (416 aa)
PRIM2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (347 aa)
POLE3DNA polymerase epsilon subunit 3. (147 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa)
PSMB5Proteasome subunit beta. (215 aa)
UBCpolyubiquitin-C. (457 aa)
ANAPC2Anaphase-promoting complex subunit 2; Belongs to the cullin family. (816 aa)
PRIM1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (411 aa)
FAM89BProtein FAM89B. (100 aa)
UBE2SUbiquitin conjugating enzyme E2 S. (222 aa)
UBE2E1Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
TM7SF3Transmembrane 7 superfamily member 3. (569 aa)
H2BC1Histone H2B; Belongs to the histone H2B family. (127 aa)
ANAPC4Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa)
PSMD926S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa)
CDC26Anaphase-promoting complex subunit CDC26 isoform X2. (85 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
MCM6DNA helicase; Belongs to the MCM family. (820 aa)
MCM3DNA helicase; Belongs to the MCM family. (801 aa)
PSMC626S protease regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (389 aa)
PSMB8Proteasome subunit beta. (247 aa)
PSMB9Proteasome subunit beta. (219 aa)
CDT1DNA replication factor Cdt1. (372 aa)
KPNB1Importin subunit beta-1. (843 aa)
H2BC18Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC101320102Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSTTRP00000004809annotation not available (130 aa)
ENSTTRP00000004818annotation not available (130 aa)
LOC101322350Histone H2B; Belongs to the histone H2B family. (126 aa)
H2AC20Histone H2A; Belongs to the histone H2A family. (129 aa)
POLA1DNA polymerase. (1467 aa)
CDC23Cell division cycle protein 23 homolog. (597 aa)
PSMA2Proteasome subunit alpha type. (234 aa)
CDC7Cell division cycle 7-related protein kinase. (572 aa)
H2BU1Histone H2B; Belongs to the histone H2B family. (126 aa)
DBF4Protein DBF4 homolog A isoform X1. (675 aa)
PSMD1426S proteasome non-ATPase regulatory subunit 14. (294 aa)
PSMD526S proteasome non-ATPase regulatory subunit 5 isoform X1. (504 aa)
PSMB3Proteasome subunit beta. (205 aa)
H2AZ2Histone H2A; Belongs to the histone H2A family. (125 aa)
PSMC526S protease regulatory subunit 8 isoform X3; Belongs to the AAA ATPase family. (406 aa)
PSMD426S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa)
PSMB2Proteasome subunit beta. (248 aa)
MCM5DNA replication licensing factor MCM5-like. (734 aa)
H2AJHistone H2A; Belongs to the histone H2A family. (103 aa)
ENSTTRP00000006970annotation not available (102 aa)
RPA2Replication protein A 32 kDa subunit. (344 aa)
POLE2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
PSMA6Proteasome subunit alpha type. (246 aa)
MCM4DNA helicase; Belongs to the MCM family. (692 aa)
PSME1Proteasome activator complex subunit 1. (248 aa)
PSME2Proteasome activator complex subunit 2. (248 aa)
FZR1Fizzy-related protein homolog. (494 aa)
ORC3Origin recognition complex subunit 3 isoform X3. (714 aa)
UBBpolyubiquitin-B. (229 aa)
UBE2D1Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
PSMB10Proteasome 20S subunit beta 10. (273 aa)
PSMA5Proteasome subunit alpha type. (241 aa)
KPNA6Importin subunit alpha; Functions in nuclear protein import. (535 aa)
ANAPC16Anaphase-promoting complex subunit 16. (110 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa)
POLE4LOW QUALITY PROTEIN: DNA polymerase epsilon subunit 4. (116 aa)
PSMF1Proteasome inhibitor PI31 subunit isoform X1. (256 aa)
KXD1KxDL motif containing 1. (176 aa)
PSMD826S proteasome non-ATPase regulatory subunit 8. (351 aa)
POLEDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2262 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
ORC5Origin recognition complex subunit 5 isoform X1. (376 aa)
ANAPC15Anaphase-promoting complex subunit 15 isoform X2. (120 aa)
KPNA5Importin subunit alpha; Functions in nuclear protein import. (581 aa)
PSMA7Proteasome subunit alpha type. (248 aa)
MCM10Protein MCM10 homolog. (872 aa)
PSMD1126S proteasome non-ATPase regulatory subunit 11. (422 aa)
MEIOBMeiosis-specific with OB domain-containing protein isoform X1. (442 aa)
PSMB4Proteasome 20S subunit beta 4. (259 aa)
PSME3Proteasome activator subunit 3. (268 aa)
ORC2Origin recognition complex subunit 2 isoform X1. (496 aa)
CREBZFCREB/ATF bZIP transcription factor isoform X2. (353 aa)
ANAPC10Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa)
ANAPC11Anaphase-promoting complex subunit 11. (193 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (718 aa)
TM4SF19Transmembrane 4 L6 family member 19. (208 aa)
MCM8DNA helicase MCM8 isoform X1; Belongs to the MCM family. (821 aa)
PSMB7Proteasome subunit beta. (277 aa)
ORC6Origin recognition complex subunit 6. (252 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
LOC101322612Uncharacterized protein LOC109551478; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa)
LOC101330510-2Histone H2B type 1-L-like. (126 aa)
LOC101320102-2Histone H4. (103 aa)
LOC101329634Histone H4. (103 aa)
LOC101329341Histone H2A; Belongs to the histone H2A family. (130 aa)
H2BC15Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC101322612-2Histone H3.1. (136 aa)
LOC101320102-3Histone H4. (103 aa)
LOC101322612-3Histone H3.1. (136 aa)
LOC101328760Histone H2B; Belongs to the histone H2B family. (126 aa)
PSMA3Proteasome subunit alpha type. (255 aa)
PSMD1326S proteasome non-ATPase regulatory subunit 13. (376 aa)
CDC27Cell division cycle protein 27 homolog isoform X3. (824 aa)
PSMC126S protease regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
PSMD626S proteasome non-ATPase regulatory subunit 6 isoform X1. (389 aa)
RPA3Replication protein A 14 kDa subunit. (121 aa)
RPS27Aubiquitin-40S ribosomal protein S27a. (156 aa)
PSMD1226S proteasome non-ATPase regulatory subunit 12 isoform X2. (455 aa)
MCM9DNA helicase MCM9 isoform X4; Belongs to the MCM family. (696 aa)
PSMD726S proteasome non-ATPase regulatory subunit 7 isoform X2. (322 aa)
PSMC326S protease regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (433 aa)
ANAPC5Anaphase-promoting complex subunit 5 isoform X1. (754 aa)
PSMB1Proteasome subunit beta. (239 aa)
CDC45Cell division control protein 45 homolog. (567 aa)
CDK2Cyclin dependent kinase 2. (298 aa)
H2AZ1Histone H2A; Belongs to the histone H2A family. (122 aa)
ANAPC7LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7. (564 aa)
CDC16Cell division cycle protein 16 homolog isoform X1. (620 aa)
H2BC11Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC101320102-4Histone H4. (103 aa)
LOC101319223Histone H2B; Belongs to the histone H2B family. (126 aa)
CDK3Cyclin dependent kinase 3. (304 aa)
UBE2CUbiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa)
PSMD126S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (949 aa)
GMNNGeminin. (210 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
ANAPC1Anaphase-promoting complex subunit 1 isoform X1. (1943 aa)
LOC101322612-4Histone H3.1. (136 aa)
ENSTTRP00000015863annotation not available (110 aa)
LOC101320102-5Histone H4. (103 aa)
LOC101322612-5Histone H3.1. (136 aa)
ENSTTRP00000015867annotation not available (130 aa)
H2BC3Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC101322612-6Histone H3.1. (136 aa)
LOC101320102-6Histone H4. (103 aa)
LOC101328661Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC101327496Histone H2B type 1-L-like isoform X1; Belongs to the histone H2B family. (125 aa)
LOC101320102-7Histone H4. (103 aa)
LOC101332610Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC101321474Histone H2A; Belongs to the histone H2A family. (130 aa)
LOC101322612-7Histone H3.1. (136 aa)
LOC101320102-8Histone H4. (103 aa)
LOC101322612-8Histone H3.1. (136 aa)
LOC101324906Histone H2B; Belongs to the histone H2B family. (126 aa)
LOC101322612-9Histone H3.1. (136 aa)
LOC101323719Histone H2B; Belongs to the histone H2B family. (125 aa)
LOC101320102-9Histone H4. (103 aa)
PSMD326S proteasome non-ATPase regulatory subunit 3. (534 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (499 aa)
MCM2Minichromosome maintenance complex component 2. (905 aa)
LOC101316193DNA polymerase alpha subunit B isoform X2. (597 aa)
UBA52ubiquitin-60S ribosomal protein L40. (128 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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