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| | MCM3 | DNA helicase; Belongs to the MCM family. (801 aa) |
| | PSMC6 | 26S protease regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (389 aa) |
| | PSMB8 | Proteasome subunit beta. (247 aa) |
| | RCBTB2 | RCC1 and BTB domain-containing protein 2 isoform X1. (550 aa) |
| | PSMB9 | Proteasome subunit beta. (219 aa) |
| | CDT1 | DNA replication factor Cdt1. (372 aa) |
| | CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa) |
| | MEIOB | Meiosis-specific with OB domain-containing protein isoform X1. (442 aa) |
| | RFC3 | Replication factor C subunit 3 isoform X2. (355 aa) |
| | FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | PSMD11 | 26S proteasome non-ATPase regulatory subunit 11. (422 aa) |
| | PSMA7 | Proteasome subunit alpha type. (248 aa) |
| | ANAPC15 | Anaphase-promoting complex subunit 15 isoform X2. (120 aa) |
| | ATAD5 | ATPase family AAA domain-containing protein 5 isoform X1. (1830 aa) |
| | POLA1 | DNA polymerase. (1467 aa) |
| | CDC23 | Cell division cycle protein 23 homolog. (597 aa) |
| | PSMA2 | Proteasome subunit alpha type. (234 aa) |
| | POLD3 | DNA polymerase delta subunit 3 isoform X1. (465 aa) |
| | POLD2 | DNA polymerase delta subunit 2. (469 aa) |
| | PSMD14 | 26S proteasome non-ATPase regulatory subunit 14. (294 aa) |
| | PSMD5 | 26S proteasome non-ATPase regulatory subunit 5 isoform X1. (504 aa) |
| | PSMB3 | Proteasome subunit beta. (205 aa) |
| | PSMC5 | 26S protease regulatory subunit 8 isoform X3; Belongs to the AAA ATPase family. (406 aa) |
| | PSMD4 | 26S proteasome non-ATPase regulatory subunit 4 isoform X1. (380 aa) |
| | PSMB2 | Proteasome subunit beta. (248 aa) |
| | PSME4 | Proteasome activator complex subunit 4 isoform X2. (1762 aa) |
| | MCM5 | DNA replication licensing factor MCM5-like. (734 aa) |
| | POLE2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | PSMA6 | Proteasome subunit alpha type. (246 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (350 aa) |
| | SKP2 | S-phase kinase-associated protein 2 isoform X2. (441 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (692 aa) |
| | GINS3 | DNA replication complex GINS protein PSF3. (216 aa) |
| | PSME1 | Proteasome activator complex subunit 1. (248 aa) |
| | PSME2 | Proteasome activator complex subunit 2. (248 aa) |
| | LIG1 | DNA ligase. (923 aa) |
| | RFC2 | Replication factor C subunit 2. (316 aa) |
| | FZR1 | Fizzy-related protein homolog. (494 aa) |
| | ORC3 | Origin recognition complex subunit 3 isoform X3. (714 aa) |
| | UBB | polyubiquitin-B. (229 aa) |
| | UBE2D1 | Ubiquitin-conjugating enzyme E2 D1 isoform X1; Belongs to the ubiquitin-conjugating enzyme family. (147 aa) |
| | PSMB10 | Proteasome 20S subunit beta 10. (273 aa) |
| | PSMA5 | Proteasome subunit alpha type. (241 aa) |
| | ANAPC16 | Anaphase-promoting complex subunit 16. (110 aa) |
| | PSMD10 | 26S proteasome non-ATPase regulatory subunit 10 isoform X1. (226 aa) |
| | POLE4 | LOW QUALITY PROTEIN: DNA polymerase epsilon subunit 4. (116 aa) |
| | PSMF1 | Proteasome inhibitor PI31 subunit isoform X1. (256 aa) |
| | KXD1 | KxDL motif containing 1. (176 aa) |
| | PSMD8 | 26S proteasome non-ATPase regulatory subunit 8. (351 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2262 aa) |
| | PSMC2 | 26S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa) |
| | ORC5 | Origin recognition complex subunit 5 isoform X1. (376 aa) |
| | PSMB11 | Proteasome subunit beta. (259 aa) |
| | UBA52 | ubiquitin-60S ribosomal protein L40. (128 aa) |
| | CUL1 | Cullin-1; Belongs to the cullin family. (767 aa) |
| | LOC101316193 | DNA polymerase alpha subunit B isoform X2. (597 aa) |
| | MCM2 | Minichromosome maintenance complex component 2. (905 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (499 aa) |
| | PSMD3 | 26S proteasome non-ATPase regulatory subunit 3. (534 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | RFC4 | Replication factor C subunit 4. (364 aa) |
| | ANAPC1 | Anaphase-promoting complex subunit 1 isoform X1. (1943 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa) |
| | GMNN | Geminin. (210 aa) |
| | PSMD1 | 26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family. (949 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | UBE2C | Ubiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) |
| | CDK3 | Cyclin dependent kinase 3. (304 aa) |
| | CDC16 | Cell division cycle protein 16 homolog isoform X1. (620 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (187 aa) |
| | ANAPC7 | LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7. (564 aa) |
| | CDK2 | Cyclin dependent kinase 2. (298 aa) |
| | PSMB1 | Proteasome subunit beta. (239 aa) |
| | PSMA8 | Proteasome subunit alpha type. (221 aa) |
| | ANAPC5 | Anaphase-promoting complex subunit 5 isoform X1. (754 aa) |
| | RFC1 | Replication factor C subunit 1-like isoform X1. (1149 aa) |
| | PSMC3 | 26S protease regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (433 aa) |
| | PSMD7 | 26S proteasome non-ATPase regulatory subunit 7 isoform X2. (322 aa) |
| | MCM9 | DNA helicase MCM9 isoform X4; Belongs to the MCM family. (696 aa) |
| | PSMD12 | 26S proteasome non-ATPase regulatory subunit 12 isoform X2. (455 aa) |
| | RPS27A | ubiquitin-40S ribosomal protein S27a. (156 aa) |
| | RPA3 | Replication protein A 14 kDa subunit. (121 aa) |
| | PSMD6 | 26S proteasome non-ATPase regulatory subunit 6 isoform X1. (389 aa) |
| | PSMC1 | 26S protease regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa) |
| | CDC27 | Cell division cycle protein 27 homolog isoform X3. (824 aa) |
| | PSMD13 | 26S proteasome non-ATPase regulatory subunit 13. (376 aa) |
| | PSMA3 | Proteasome subunit alpha type. (255 aa) |
| | DNA2 | DNA replication ATP-dependent helicase/nuclease DNA2 isoform X1. (1059 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | PSMB7 | Proteasome subunit beta. (277 aa) |
| | RCBTB1 | RCC1 and BTB domain-containing protein 1 isoform X2. (531 aa) |
| | MCM8 | DNA helicase MCM8 isoform X1; Belongs to the MCM family. (821 aa) |
| | TM4SF19 | Transmembrane 4 L6 family member 19. (208 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (718 aa) |
| | ANAPC11 | Anaphase-promoting complex subunit 11. (193 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1. (82 aa) |
| | ORC2 | Origin recognition complex subunit 2 isoform X1. (496 aa) |
| | PSME3 | Proteasome activator subunit 3. (268 aa) |
| | PSMB4 | Proteasome 20S subunit beta 4. (259 aa) |
| | PSMB6 | Proteasome subunit beta type-6. (238 aa) |
| | RFC5 | Replication factor C subunit 5. (341 aa) |
| | PSMA4 | Proteasome subunit alpha type. (258 aa) |
| | PSMC4 | 26S protease regulatory subunit 6B isoform X2; Belongs to the AAA ATPase family. (416 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (347 aa) |
| | POLE3 | DNA polymerase epsilon subunit 3. (147 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa) |
| | PSMB5 | Proteasome subunit beta. (215 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (431 aa) |
| | GINS1 | DNA replication complex GINS protein PSF1 isoform X3. (196 aa) |
| | UBC | polyubiquitin-C. (457 aa) |
| | ENSTTRP00000001764 | annotation not available (98 aa) |
| | ANAPC2 | Anaphase-promoting complex subunit 2; Belongs to the cullin family. (816 aa) |
| | PRIM1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (411 aa) |
| | FAM89B | Protein FAM89B. (100 aa) |
| | POLD1 | LOW QUALITY PROTEIN: DNA polymerase delta catalytic subunit. (1125 aa) |
| | UBE2S | Ubiquitin conjugating enzyme E2 S. (222 aa) |
| | UBE2E1 | Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa) |
| | TM7SF3 | Transmembrane 7 superfamily member 3. (569 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa) |
| | PSMD9 | 26S proteasome non-ATPase regulatory subunit 9 isoform X1. (223 aa) |
| | CDC26 | Anaphase-promoting complex subunit CDC26 isoform X2. (85 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (222 aa) |
| | PSMA1 | Proteasome subunit alpha type. (269 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (820 aa) |
| | CCNA1 | cyclin-A1 isoform X1; Belongs to the cyclin family. (464 aa) |
