STRINGSTRING
EIF4A3 EIF4A3 SUMO1 SUMO1 LOC109547770 LOC109547770 MX1 MX1 SOCS3 SOCS3 CAMK2D CAMK2D TRIM68 TRIM68 IRF6 IRF6 STAT1 STAT1 PPM1B PPM1B IRF4 IRF4 ENSTTRP00000001835 ENSTTRP00000001835 UBE2L6 UBE2L6 PRKCD PRKCD OAS1 OAS1 OAS2 OAS2 UBE2E1 UBE2E1 MID2 MID2 IRF1 IRF1 PLCG1 PLCG1 TRIM35 TRIM35 UBE2N UBE2N HERC5 HERC5 LOC101334165 LOC101334165 IFI27L2 IFI27L2 EIF4E EIF4E LOC101337451 LOC101337451 GBP2 GBP2 KPNB1 KPNB1 PTPN6 PTPN6 CIITA CIITA UBA7 UBA7 EIF4E3 EIF4E3 IFNK IFNK EGR1 EGR1 IRF3 IRF3 MAPK3 MAPK3 USP18 USP18 TRIM2 TRIM2 ATL2 ATL2 TRIM17 TRIM17 IFNG IFNG EIF2AK2 EIF2AK2 LOC109549916 LOC109549916 STAT2 STAT2 RSAD2 RSAD2 MID1 MID1 DDX58 DDX58 EIF4A2 EIF4A2 TRIM38 TRIM38 IFNB1 IFNB1 IFNGR1 IFNGR1 ENSTTRP00000015187 ENSTTRP00000015187 PIAS1 PIAS1 TRIM65 TRIM65 TRIM47 TRIM47 GBP6 GBP6 IFIT5 IFIT5 IFIT1 IFIT1 FLNB FLNB TRIM45 TRIM45 IFNAR1 IFNAR1 PDE12 PDE12 ISG20 ISG20 CAMK2A CAMK2A PTPN1 PTPN1 EIF4G2 EIF4G2 EIF4E1B EIF4E1B KPNA1 KPNA1 ATL3 ATL3 ENSTTRP00000012558 ENSTTRP00000012558 ISG15 ISG15 IFNGR2 IFNGR2 TRIM3 TRIM3 TRIM8 TRIM8 ENSTTRP00000011905 ENSTTRP00000011905 PTPN2 PTPN2 ABCE1 ABCE1 CAMK2G CAMK2G ARIH1 ARIH1 IFI35 IFI35 TRIM29 TRIM29 JAK2 JAK2 EIF4G3 EIF4G3 EIF4G1 EIF4G1 EIF4E2 EIF4E2 TRIM62 TRIM62 TRIM14 TRIM14 TRIM42 TRIM42 GBP1 GBP1 EIF4A1 EIF4A1 IFNAR2 IFNAR2 JAK1 JAK1 ATL1 ATL1 TYK2 TYK2 TRIM46 TRIM46 IRF2 IRF2 PTPN11 PTPN11 KPNA3 KPNA3 IRF9 IRF9 TRIM10 TRIM10 IFI6 IFI6 ENSTTRP00000007887 ENSTTRP00000007887 ENSTTRP00000007676 ENSTTRP00000007676 LOC109549914 LOC109549914 TRIM25 TRIM25 ENSTTRP00000007660 ENSTTRP00000007660 NEDD4 NEDD4 FOXS1 FOXS1 CAMK2B CAMK2B RNASEL RNASEL KPNA4 KPNA4 ENSTTRP00000000476 ENSTTRP00000000476
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (354 aa)
SUMO1Small ubiquitin-related modifier. (142 aa)
LOC109547770Interferon-induced GTP-binding protein Mx2-like. (461 aa)
MX1LOW QUALITY PROTEIN: interferon-induced GTP-binding protein Mx1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (496 aa)
SOCS3Suppressor of cytokine signaling 3. (229 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4; Belongs to the protein kinase superfamily. (498 aa)
TRIM68E3 ubiquitin-protein ligase TRIM68 isoform X1. (485 aa)
IRF6Interferon regulatory factor 6 isoform X2. (467 aa)
STAT1Signal transducer and activator of transcription. (720 aa)
PPM1BProtein phosphatase 1B isoform X1. (378 aa)
IRF4Interferon regulatory factor 4 isoform X1. (451 aa)
ENSTTRP00000001835annotation not available (349 aa)
UBE2L6ubiquitin/ISG15-conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
PRKCDProtein kinase C delta. (671 aa)
OAS12'-5'-oligoadenylate synthase 1. (407 aa)
OAS2LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 2. (693 aa)
UBE2E1Ubiquitin-conjugating enzyme E2 E1; Belongs to the ubiquitin-conjugating enzyme family. (193 aa)
MID2Probable E3 ubiquitin-protein ligase MID2 isoform X6. (715 aa)
IRF1Interferon regulatory factor. (318 aa)
PLCG1Phosphoinositide phospholipase C. (1290 aa)
TRIM35Tripartite motif-containing protein 35. (491 aa)
UBE2NUbiquitin-conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
HERC5E3 ISG15--protein ligase HERC5 isoform X2. (1018 aa)
LOC101334165Uncharacterized protein LOC101334165 isoform X1. (94 aa)
IFI27L2Uncharacterized protein LOC101334745. (130 aa)
EIF4EEukaryotic translation initiation factor 4E isoform X2; Belongs to the eukaryotic initiation factor 4E family. (211 aa)
LOC101337451Guanylate-binding protein 4. (628 aa)
GBP2LOW QUALITY PROTEIN: guanylate-binding protein 2-like. (548 aa)
KPNB1Importin subunit beta-1. (843 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type 6. (620 aa)
CIITAMHC class II transactivator. (1159 aa)
UBA7Ubiquitin like modifier activating enzyme 7. (1010 aa)
EIF4E3Eukaryotic translation initiation factor 4E type 3 isoform X2; Belongs to the eukaryotic initiation factor 4E family. (165 aa)
IFNKInterferon kappa. (207 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (509 aa)
IRF3Interferon regulatory factor 3. (438 aa)
MAPK3Mitogen-activated protein kinase 3. (382 aa)
USP18Ubl carboxyl-terminal hydrolase 18 isoform X1; Belongs to the peptidase C19 family. (359 aa)
TRIM2Tripartite motif-containing protein 2 isoform X1. (744 aa)
ATL2Atlastin-2 isoform X1. (583 aa)
TRIM17E3 ubiquitin-protein ligase TRIM17-like. (470 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons (By similarity); Belongs to the type II (or gamma) interferon family. (166 aa)
EIF2AK2Interferon-induced, double-stranded RNA-activated protein kinase isoform X1. (539 aa)
LOC109549916Interferon omega-1-like. (195 aa)
STAT2Signal transducer and activator of transcription. (849 aa)
RSAD2Radical S-adenosyl methionine domain-containing protein 2. (307 aa)
MID1E3 ubiquitin-protein ligase Midline-1 isoform X1. (667 aa)
DDX58LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DDX58. (771 aa)
EIF4A2Eukaryotic translation initiation factor 4A2. (407 aa)
TRIM38E3 ubiquitin-protein ligase TRIM38. (461 aa)
IFNB1Interferon beta. (185 aa)
IFNGR1Interferon gamma receptor 1. (463 aa)
ENSTTRP00000015187annotation not available (367 aa)
PIAS1E3 SUMO-protein ligase PIAS1 isoform X1. (682 aa)
TRIM65Tripartite motif-containing protein 65 isoform X1. (511 aa)
TRIM47Tripartite motif-containing protein 47 isoform X4. (638 aa)
GBP6Guanylate-binding protein 6. (632 aa)
IFIT5Interferon-induced protein with tetratricopeptide repeats 5. (482 aa)
IFIT1Interferon-induced protein with tetratricopeptide repeats 1 isoform X1. (476 aa)
FLNBfilamin-B isoform X2. (2600 aa)
TRIM45Tripartite motif-containing protein 45. (577 aa)
IFNAR1Interferon alpha/beta receptor 1 isoform X1. (536 aa)
PDE122',5'-phosphodiesterase 12. (609 aa)
ISG20Interferon-stimulated gene 20 kDa protein. (176 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (539 aa)
PTPN1Tyrosine-protein phosphatase non-receptor type. (428 aa)
EIF4G2Eukaryotic translation initiation factor 4 gamma 2. (903 aa)
EIF4E1BEukaryotic translation initiation factor 4E family member 1B. (210 aa)
KPNA1Importin subunit alpha; Functions in nuclear protein import. (538 aa)
ATL3Atlastin-3 isoform X1. (565 aa)
ENSTTRP00000012558annotation not available (443 aa)
ISG15ISG15 ubiquitin like modifier. (166 aa)
IFNGR2Interferon gamma receptor 2. (311 aa)
TRIM3Tripartite motif containing 3. (743 aa)
TRIM8Probable E3 ubiquitin-protein ligase TRIM8 isoform X2. (548 aa)
ENSTTRP00000011905annotation not available (362 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (386 aa)
ABCE1ATP-binding cassette sub-family E member 1. (594 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X5. (535 aa)
ARIH1RBR-type E3 ubiquitin transferase. (502 aa)
IFI35Interferon-induced 35 kDa protein isoform X1. (279 aa)
TRIM29Tripartite motif-containing protein 29. (584 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
EIF4G3Eukaryotic translation initiation factor 4 gamma 3 isoform X4. (1581 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1537 aa)
EIF4E2Eukaryotic translation initiation factor 4E type 2 isoform X1; Belongs to the eukaryotic initiation factor 4E family. (245 aa)
TRIM62E3 ubiquitin-protein ligase TRIM62. (339 aa)
TRIM14LOW QUALITY PROTEIN: tripartite motif-containing protein 14. (440 aa)
TRIM42Tripartite motif-containing protein 42 isoform X1. (723 aa)
GBP1Guanylate-binding protein 1-like. (552 aa)
EIF4A1Eukaryotic initiation factor 4A-I isoform X1; Belongs to the DEAD box helicase family. (406 aa)
IFNAR2Interferon alpha/beta receptor 2 isoform X1. (514 aa)
JAK1Tyrosine-protein kinase. (1154 aa)
ATL1Atlastin-1 isoform X1. (558 aa)
TYK2Tyrosine kinase 2. (1182 aa)
TRIM46Tripartite motif containing 46. (751 aa)
IRF2Interferon regulatory factor. (315 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
KPNA3Importin subunit alpha; Functions in nuclear protein import. (498 aa)
IRF9Interferon regulatory factor 9. (392 aa)
TRIM10Tripartite motif-containing protein 10. (481 aa)
IFI6Interferon alpha-inducible protein 6 isoform X1. (125 aa)
ENSTTRP00000007887annotation not available (134 aa)
ENSTTRP00000007676annotation not available (195 aa)
LOC109549914Interferon alpha-4-like. (189 aa)
TRIM25E3 ubiquitin/ISG15 ligase TRIM25 isoform X1. (475 aa)
ENSTTRP00000007660annotation not available (189 aa)
NEDD4E3 ubiquitin-protein ligase. (1193 aa)
FOXS1Forkhead box S1. (330 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (489 aa)
RNASEL2-5A-dependent ribonuclease isoform X2. (736 aa)
KPNA4Importin subunit alpha; Functions in nuclear protein import. (498 aa)
ENSTTRP00000000476annotation not available (195 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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