STRINGSTRING
ABCG2 ABCG2 TOR4A TOR4A NVL NVL RAD51D RAD51D RAD51B RAD51B NLRP10 NLRP10 ABCB9 ABCB9 YME1L1 YME1L1 ORC1 ORC1 ATAD1 ATAD1 ORC4 ORC4 DNAH3 DNAH3 TOR2A TOR2A RFC4 RFC4 CDC6 CDC6 ATAD3A ATAD3A CFTR CFTR ABCC9 ABCC9 TOR3A TOR3A DNAH7 DNAH7 CLPX CLPX SNRNP200 SNRNP200 ATAD5 ATAD5 DNAH8 DNAH8 DYNC1H1 DYNC1H1 SPG7 SPG7 ABCA12 ABCA12 TAP1 TAP1 TAP2 TAP2 AK9 AK9 PSMC6 PSMC6 MCM3 MCM3 AFG3L2 AFG3L2 NSF NSF ABCA5 ABCA5 ABCC5 ABCC5 DNAH10 DNAH10 ABCB7 ABCB7 NLRP9 NLRP9 ATP5F1B ATP5F1B ABCA2 ABCA2 DNAH11 DNAH11 RUVBL2 RUVBL2 DNAH1 DNAH1 KATNAL2 KATNAL2 RUVBL1 RUVBL1 FIGN FIGN ABCA4 ABCA4 ABCF2 ABCF2 ABCB8 ABCB8 ABCC4 ABCC4 ABCG1 ABCG1 PSMC4 PSMC4 RFC5 RFC5 RNF213 RNF213 SPAST SPAST NLRP8 NLRP8 ABCC3 ABCC3 LOC101330933-2 LOC101330933-2 ATAD2 ATAD2 ABCG4 ABCG4 DMC1 DMC1 KATNAL1 KATNAL1 NAV1 NAV1 KATNA1 KATNA1 DNAH6 DNAH6 ABCB11 ABCB11 VCP VCP ABCC10 ABCC10 ABCG5 ABCG5 ABCD4 ABCD4 ABCB4 ABCB4 ABCB1 ABCB1 PSMC5 PSMC5 PEX6 PEX6 VWA8 VWA8 NAV3 NAV3 MDN1 MDN1 SPATA5L1 SPATA5L1 ABCD3 ABCD3 SPATA5 SPATA5 ABCA3 ABCA3 ASCC3 ASCC3 ABCF1 ABCF1 ABCF3 ABCF3 RFC2 RFC2 TRIP13 TRIP13 ABCB10 ABCB10 CLPB CLPB VPS4A VPS4A ABCB6 ABCB6 CHTF18 CHTF18 DNAH2 DNAH2 ABCC1 ABCC1 ABCC6 ABCC6 ABCA1 ABCA1 RAD51 RAD51 PSMC2 PSMC2 DNAH5 DNAH5 RFC3 RFC3 PEX1 PEX1 ABCD1 ABCD1 DHX15 DHX15 ABCC2 ABCC2 ABCE1 ABCE1 MCM7 MCM7 ABCD2 ABCD2 MCM8 MCM8 ABCB5 ABCB5 PSMC1 PSMC1 LONP1 LONP1 ATAD2B ATAD2B FIGNL2 FIGNL2 PSMC3 PSMC3 RFC1 RFC1 ABCC8 ABCC8 ABCC12 ABCC12 ABCC11 ABCC11 LONP2 LONP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABCG2ATP-binding cassette sub-family G member 2. (653 aa)
TOR4Atorsin-4A. (416 aa)
NVLNuclear valosin-containing protein-like. (856 aa)
RAD51DDNA repair protein RAD51 homolog 4. (305 aa)
RAD51BDNA repair protein RAD51 homolog 2 isoform X2. (345 aa)
NLRP10LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 10. (530 aa)
ABCB9ATP-binding cassette sub-family B member 9. (765 aa)
YME1L1ATP-dependent zinc metalloprotease YME1L1. (764 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa)
ATAD1ATPase family AAA domain-containing protein 1; Belongs to the AAA ATPase family. (361 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa)
DNAH3Dynein heavy chain 3, axonemal. (4109 aa)
TOR2ATorsin. (321 aa)
RFC4Replication factor C subunit 4. (364 aa)
CDC6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (499 aa)
ATAD3AATPase family AAA domain-containing protein 3A. (557 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1480 aa)
ABCC9ATP-binding cassette sub-family C member 9. (1540 aa)
TOR3Atorsin-3A isoform X1. (400 aa)
DNAH7Dynein heavy chain 7, axonemal. (4021 aa)
CLPXATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial. (634 aa)
SNRNP200U5 small nuclear ribonucleoprotein 200 kDa helicase. (2135 aa)
ATAD5ATPase family AAA domain-containing protein 5 isoform X1. (1830 aa)
DNAH8Dynein heavy chain 8, axonemal. (4701 aa)
DYNC1H1Cytoplasmic dynein 1 heavy chain 1. (4640 aa)
SPG7LOW QUALITY PROTEIN: paraplegin; Belongs to the AAA ATPase family. (792 aa)
ABCA12ATP-binding cassette sub-family A member 12 isoform X1. (2575 aa)
TAP1Antigen peptide transporter 1. (811 aa)
TAP2Antigen peptide transporter 2 isoform X1. (484 aa)
AK9Adenylate kinase 9. (745 aa)
PSMC626S protease regulatory subunit 10B isoform X1; Belongs to the AAA ATPase family. (389 aa)
MCM3DNA helicase; Belongs to the MCM family. (801 aa)
AFG3L2AFG3-like protein 2 isoform X1. (793 aa)
NSFVesicle-fusing ATPase isoform X4. (737 aa)
ABCA5ATP-binding cassette sub-family A member 5. (1643 aa)
ABCC5Multidrug resistance-associated protein 5 isoform X1. (1437 aa)
DNAH10Dynein heavy chain 10, axonemal. (3063 aa)
ABCB7ATP-binding cassette sub-family B member 7, mitochondrial isoform X1. (754 aa)
NLRP9NACHT, LRR and PYD domains-containing protein 9. (995 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (529 aa)
ABCA2ATP binding cassette subfamily A member 2. (2202 aa)
DNAH11LOW QUALITY PROTEIN: dynein heavy chain 11, axonemal. (4523 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (443 aa)
DNAH1LOW QUALITY PROTEIN: dynein heavy chain 1, axonemal. (4311 aa)
KATNAL2Katanin p60 ATPase-containing subunit A-like 2; Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays. (464 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (454 aa)
FIGNFidgetin isoform X1; Belongs to the AAA ATPase family. (759 aa)
ABCA4Retinal-specific ATP-binding cassette transporter isoform X2. (2297 aa)
ABCF2ATP-binding cassette sub-family F member 2. (636 aa)
ABCB8ATP-binding cassette sub-family B member 8, mitochondrial. (730 aa)
ABCC4Multidrug resistance-associated protein 4. (1271 aa)
ABCG1ATP-binding cassette sub-family G member 1 isoform X1. (631 aa)
PSMC426S protease regulatory subunit 6B isoform X2; Belongs to the AAA ATPase family. (416 aa)
RFC5Replication factor C subunit 5. (341 aa)
RNF213E3 ubiquitin-protein ligase RNF213. (3260 aa)
SPASTSpastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] (609 aa)
NLRP8NACHT, LRR and PYD domains-containing protein 8. (1047 aa)
ABCC3Canalicular multispecific organic anion transporter 2. (1519 aa)
LOC101330933-2Baculoviral IAP repeat-containing protein 1 isoform X6. (1061 aa)
ATAD2ATPase family AAA domain-containing protein 2 isoform X1. (1321 aa)
ABCG4ATP-binding cassette sub-family G member 4. (646 aa)
DMC1Meiotic recombination protein DMC1/LIM15 homolog; Belongs to the RecA family. (340 aa)
KATNAL1Katanin p60 ATPase-containing subunit A-like 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neur [...] (489 aa)
NAV1Neuron navigator 1. (1822 aa)
KATNA1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (491 aa)
DNAH6Dynein heavy chain 6, axonemal. (2182 aa)
ABCB11Bile salt export pump isoform X1. (1323 aa)
VCPTransitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. (795 aa)
ABCC10Multidrug resistance-associated protein 7. (1492 aa)
ABCG5ATP-binding cassette sub-family G member 5. (652 aa)
ABCD4ATP-binding cassette sub-family D member 4. (605 aa)
ABCB4Phosphatidylcholine translocator ABCB4 isoform X1. (1254 aa)
ABCB1Multidrug resistance protein 1. (1276 aa)
PSMC526S protease regulatory subunit 8 isoform X3; Belongs to the AAA ATPase family. (406 aa)
PEX6Peroxisome biogenesis factor 6. (959 aa)
VWA8Von Willebrand factor A domain-containing protein 8 isoform X1. (1904 aa)
NAV3Neuron navigator 3 isoform X1. (2376 aa)
MDN1Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5576 aa)
SPATA5L1Spermatogenesis-associated protein 5-like protein 1 isoform X1. (753 aa)
ABCD3ATP-binding cassette sub-family D member 3 isoform X2. (621 aa)
SPATA5Spermatogenesis-associated protein 5 isoform X1. (884 aa)
ABCA3ATP-binding cassette sub-family A member 3. (1693 aa)
ASCC3Activating signal cointegrator 1 complex subunit 3 isoform X1. (2196 aa)
ABCF1ATP binding cassette subfamily F member 1. (840 aa)
ABCF3ATP-binding cassette sub-family F member 3. (707 aa)
RFC2Replication factor C subunit 2. (316 aa)
TRIP13Pachytene checkpoint protein 2 homolog. (434 aa)
ABCB10ATP binding cassette subfamily B member 10. (743 aa)
CLPBCaseinolytic peptidase B protein homolog. (707 aa)
VPS4AVacuolar protein sorting-associated protein 4A isoform X1; Belongs to the AAA ATPase family. (433 aa)
ABCB6ATP binding cassette subfamily B member 6 (Langereis blood group). (844 aa)
CHTF18Chromosome transmission fidelity protein 18 homolog. (1090 aa)
DNAH2Dynein axonemal heavy chain 2. (4459 aa)
ABCC1Multidrug resistance-associated protein 1. (1522 aa)
ABCC6Multidrug resistance-associated protein 6. (1503 aa)
ABCA1ATP-binding cassette sub-family A member 1 isoform X1. (1908 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (299 aa)
PSMC226S protease regulatory subunit 7; Belongs to the AAA ATPase family. (433 aa)
DNAH5Dynein heavy chain 5, axonemal. (4616 aa)
RFC3Replication factor C subunit 3 isoform X2. (355 aa)
PEX1Peroxisome biogenesis factor 1. (1282 aa)
ABCD1ATP-binding cassette sub-family D member 1. (634 aa)
DHX15pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15. (794 aa)
ABCC2Canalicular multispecific organic anion transporter 1. (1543 aa)
ABCE1ATP-binding cassette sub-family E member 1. (594 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (718 aa)
ABCD2ATP binding cassette subfamily D member 2. (664 aa)
MCM8DNA helicase MCM8 isoform X1; Belongs to the MCM family. (821 aa)
ABCB5LOW QUALITY PROTEIN: ATP-binding cassette sub-family B member 5. (1245 aa)
PSMC126S protease regulatory subunit 4 isoform X1; Belongs to the AAA ATPase family. (440 aa)
LONP1Lon peptidase 1, mitochondrial. (956 aa)
ATAD2BATPase family AAA domain-containing protein 2B isoform X1. (1456 aa)
FIGNL2Putative fidgetin-like protein 2. (583 aa)
PSMC326S protease regulatory subunit 6A isoform X1; Belongs to the AAA ATPase family. (433 aa)
RFC1Replication factor C subunit 1-like isoform X1. (1149 aa)
ABCC8ATP-binding cassette sub-family C member 8. (1575 aa)
ABCC12LOW QUALITY PROTEIN: multidrug resistance-associated protein 9. (1338 aa)
ABCC11ATP binding cassette subfamily C member 11. (1263 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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