STRINGSTRING
SMG5 SMG5 PPP2CB PPP2CB LOC101332449 LOC101332449 PPP2R1A PPP2R1A FNBP4 FNBP4 NCBP1 NCBP1 EIF4A3 EIF4A3 CPSF3 CPSF3 CZIB CZIB MAGOH MAGOH PCF11 PCF11 SMG6 SMG6 WDR82 WDR82 MAGOHB MAGOHB TARDBP TARDBP ACIN1 ACIN1 PELO PELO CPSF1 CPSF1 CLP1 CLP1 MSI2 MSI2 ZC3H4 ZC3H4 PPP2R5E PPP2R5E LOC101326630 LOC101326630 TMEM223 TMEM223 NXF1 NXF1 RNF141 RNF141 RBBP6 RBBP6 CPSF4 CPSF4 PPP2R3A PPP2R3A CSTF2T CSTF2T BOLL BOLL HBS1L HBS1L MORN1 MORN1 WDR90 WDR90 ENSTTRP00000003903 ENSTTRP00000003903 LOC101323346 LOC101323346 PPP2R5C PPP2R5C PABPN1L PABPN1L PABPC1 PABPC1 PYM1 PYM1 PPP2R2A PPP2R2A TWF2 TWF2 COPS5 COPS5 PPP1R42 PPP1R42 PIH1D3 PIH1D3 PNN PNN ENSTTRP00000016165 ENSTTRP00000016165 ENSTTRP00000016164 ENSTTRP00000016164 INTS11 INTS11 SAP18 SAP18 CASC3 CASC3 MSL1 MSL1 PPP2CA PPP2CA UPF2 UPF2 CSTF3 CSTF3 RNMT RNMT RBMX2 RBMX2 PPP2R2C PPP2R2C PPP2R2B PPP2R2B FIP1L1 FIP1L1 ENSTTRP00000014765 ENSTTRP00000014765 LOC101323349 LOC101323349 FUS FUS LOC109547780 LOC109547780 UPF3A UPF3A JAZF1 JAZF1 PPP2R5A PPP2R5A PARP12 PARP12 POLDIP3 POLDIP3 ZC3H3 ZC3H3 PPP1CC PPP1CC CSTF1 CSTF1 SMG7 SMG7 DAZAP1 DAZAP1 PABPC4 PABPC4 PPP4R1 PPP4R1 SYMPK SYMPK DDX39B DDX39B RNGTT RNGTT CPSF6 CPSF6 NCBP2 NCBP2 CSTF2 CSTF2 NUDT21 NUDT21 C3orf67 C3orf67 PPP1CA PPP1CA LOC101335974 LOC101335974 ZC3H6 ZC3H6 ZC3H8 ZC3H8 DCLRE1B DCLRE1B ALYREF ALYREF DDX25 DDX25 WDR77 WDR77 DCLRE1A DCLRE1A GSPT1 GSPT1 WDR33 WDR33 GLE1 GLE1 UPF1 UPF1 ST13 ST13 UPF3B UPF3B NXT1 NXT1 LOC109548436 LOC109548436 TMEM258 TMEM258 CPSF7 CPSF7 CIRBP CIRBP KIAA1614 KIAA1614 GSPT2 GSPT2 PPP2R1B PPP2R1B TWF1 TWF1 SERAC1 SERAC1 MKRN1 MKRN1 SRRM1 SRRM1 NEDD1 NEDD1 INTS9 INTS9 RBM8A RBM8A PPP2R5B PPP2R5B CPSF2 CPSF2 RBM3 RBM3 PARP11 PARP11 CFAP20 CFAP20 PPP1CB PPP1CB RNPS1 RNPS1 PPP2R2D PPP2R2D PPP2R3C PPP2R3C DDX39A DDX39A PABPC1L PABPC1L EIF2A EIF2A NXF3 NXF3 PPP4R4 PPP4R4 PPP2R5D PPP2R5D PAPOLG PAPOLG ZC3HAV1 ZC3HAV1 DDX19B DDX19B LOC109547085 LOC109547085 PAPOLA PAPOLA MSI1 MSI1 ENSTTRP00000005246 ENSTTRP00000005246 ETF1 ETF1 SMG1 SMG1 CPSF4L CPSF4L ZGRF1 ZGRF1 ENSTTRP00000004905 ENSTTRP00000004905 NXT2 NXT2 YTHDC1 YTHDC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMG5LOW QUALITY PROTEIN: protein SMG5. (1014 aa)
PPP2CBProtein phosphatase 2 catalytic subunit beta. (285 aa)
LOC101332449Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (318 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like. (589 aa)
FNBP4Formin-binding protein 4 isoform X2. (1015 aa)
NCBP1Nuclear cap-binding protein subunit 1 isoform X1. (790 aa)
EIF4A3Eukaryotic initiation factor 4A-III; Belongs to the DEAD box helicase family. (354 aa)
CPSF3Cleavage and polyadenylation specificity factor subunit 3 isoform X5. (683 aa)
CZIBUPF0587 protein C1orf123 homolog isoform X1. (160 aa)
MAGOHMago homolog, exon junction complex subunit. (147 aa)
PCF11pre-mRNA cleavage complex 2 protein Pcf11 isoform X2. (1491 aa)
SMG6Telomerase-binding protein EST1A. (1410 aa)
WDR82WD repeat-containing protein 82 isoform X1. (259 aa)
MAGOHBProtein mago nashi homolog 2 isoform X1. (148 aa)
TARDBPTAR DNA-binding protein 43. (411 aa)
ACIN1Apoptotic chromatin condensation inducer in the nucleus isoform X1. (1334 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
CPSF1Cleavage and polyadenylation specificity factor subunit 1. (1442 aa)
CLP1Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa)
MSI2RNA-binding protein Musashi homolog 2 isoform X1. (238 aa)
ZC3H4Zinc finger CCCH-type containing 4. (1305 aa)
PPP2R5EProtein phosphatase 2 regulatory subunit B'epsilon. (467 aa)
LOC101326630Speckle targeted PIP5K1A-regulated poly(A) polymerase isoform X3. (871 aa)
TMEM223Transmembrane protein 223. (207 aa)
NXF1Nuclear RNA export factor 1 isoform X4. (618 aa)
RNF141RING finger protein 141. (231 aa)
RBBP6E3 ubiquitin-protein ligase RBBP6 isoform X1. (1781 aa)
CPSF4Cleavage and polyadenylation specificity factor subunit 4 isoform X7. (269 aa)
PPP2R3ASerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1. (1147 aa)
CSTF2TCleavage stimulation factor subunit 2 tau variant. (609 aa)
BOLLProtein boule-like isoform X1. (334 aa)
HBS1LHBS1-like protein isoform X2. (683 aa)
MORN1MORN repeat-containing protein 1. (417 aa)
WDR90WD repeat-containing protein 90. (1742 aa)
ENSTTRP00000003903annotation not available (624 aa)
LOC101323346Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (491 aa)
PPP2R5CSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (531 aa)
PABPN1LPABPN1 like, cytoplasmic. (277 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (620 aa)
PYM1Partner of Y14 and mago. (204 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (505 aa)
TWF2Twinfilin-2 isoform X1. (349 aa)
COPS5COP9 signalosome complex subunit 5 isoform X1. (334 aa)
PPP1R42Protein phosphatase 1 regulatory subunit 42 isoform X1. (228 aa)
PIH1D3Protein PIH1D3. (200 aa)
PNNPinin. (705 aa)
ENSTTRP00000016165annotation not available (194 aa)
ENSTTRP00000016164annotation not available (195 aa)
INTS11Integrator complex subunit 11. (599 aa)
SAP18Histone deacetylase complex subunit SAP18. (153 aa)
CASC3Protein CASC3. (604 aa)
MSL1Male-specific lethal 1 homolog isoform X1. (413 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
UPF2Regulator of nonsense transcripts 2 isoform X2. (1270 aa)
CSTF3Cleavage stimulation factor subunit 3 isoform X1. (714 aa)
RNMTmRNA cap guanine-N7 methyltransferase. (477 aa)
RBMX2RNA-binding motif protein, X-linked 2 isoform X1. (337 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (423 aa)
PPP2R2BProtein phosphatase 2 regulatory subunit Bbeta. (509 aa)
FIP1L1pre-mRNA 3'-end-processing factor FIP1 isoform X4. (550 aa)
ENSTTRP00000014765annotation not available (408 aa)
LOC101323349LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 4 regulatory subunit 1-like. (437 aa)
FUSRNA-binding protein FUS. (506 aa)
LOC109547780LOW QUALITY PROTEIN: RNA/RNP complex-1-interacting phosphatase-like. (179 aa)
UPF3ARegulator of nonsense transcripts 3A isoform X1. (477 aa)
JAZF1Juxtaposed with another zinc finger protein 1. (243 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa)
PARP12Poly [ADP-ribose] polymerase 12 isoform X1. (699 aa)
POLDIP3Polymerase delta-interacting protein 3 isoform X1. (401 aa)
ZC3H3Zinc finger CCCH domain-containing protein 3. (884 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (293 aa)
CSTF1Cleavage stimulation factor subunit 1. (431 aa)
SMG7Protein SMG7 isoform X8. (1171 aa)
DAZAP1DAZ associated protein 1. (397 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (555 aa)
PPP4R1Serine/threonine-protein phosphatase 4 regulatory subunit 1 isoform X5. (921 aa)
SYMPKSymplekin. (1275 aa)
DDX39BDExD-box helicase 39B. (432 aa)
RNGTTPolynucleotide 5'-triphosphatase; Bifunctional mRNA-capping enzyme exhibiting RNA 5'- triphosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the gmp moiety of GTP to the 5'-diphosphate terminus. (574 aa)
CPSF6Cleavage and polyadenylation specificity factor subunit 6 isoform X2. (566 aa)
NCBP2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (156 aa)
CSTF2Cleavage stimulation factor subunit 2. (577 aa)
NUDT21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)
C3orf67Chromosome 3 open reading frame 67. (556 aa)
PPP1CAProtein phosphatase 1 catalytic subunit alpha. (321 aa)
LOC101335974Polyadenylate-binding protein 1-like 2. (200 aa)
ZC3H6Zinc finger CCCH domain-containing protein 6 isoform X2. (1173 aa)
ZC3H8Zinc finger CCCH domain-containing protein 8 isoform X1. (308 aa)
DCLRE1B5' exonuclease Apollo. (468 aa)
ALYREFTHO complex subunit 4. (255 aa)
DDX25ATP-dependent RNA helicase DDX25. (483 aa)
WDR77Methylosome protein 50 isoform X1. (341 aa)
DCLRE1ADNA cross-link repair 1A protein. (1044 aa)
GSPT1Eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1. (707 aa)
WDR33pre-mRNA 3' end processing protein WDR33 isoform X6. (1328 aa)
GLE1Nucleoporin GLE1. (698 aa)
UPF1Regulator of nonsense transcripts 1 isoform X2. (1112 aa)
ST13Hsc70-interacting protein isoform X1. (369 aa)
UPF3BRegulator of nonsense transcripts 3B isoform X1. (477 aa)
NXT1NTF2-related export protein 1 isoform X2. (140 aa)
LOC109548436Nuclear RNA export factor 5-like. (356 aa)
TMEM258Transmembrane protein 258. (79 aa)
CPSF7Cleavage and polyadenylation specificity factor subunit 7 isoform X3. (452 aa)
CIRBPCold-inducible RNA-binding protein. (172 aa)
KIAA1614Uncharacterized protein KIAA1614 homolog. (1172 aa)
GSPT2Eukaryotic peptide chain release factor GTP-binding subunit ERF3B. (632 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (664 aa)
TWF1Twinfilin-1. (341 aa)
SERAC1Protein SERAC1 isoform X2. (654 aa)
MKRN1E3 ubiquitin-protein ligase makorin-1-like. (441 aa)
SRRM1Serine/arginine repetitive matrix protein 1 isoform X1. (901 aa)
NEDD1Protein NEDD1 isoform X2. (653 aa)
INTS9Integrator complex subunit 9 isoform X4. (658 aa)
RBM8ARNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (151 aa)
PPP2R5BSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (496 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (780 aa)
RBM3LOW QUALITY PROTEIN: RNA-binding protein 3-like. (156 aa)
PARP11Poly [ADP-ribose] polymerase. (331 aa)
CFAP20Cilia- and flagella-associated protein 20 isoform X1. (193 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (367 aa)
RNPS1RNA-binding protein with serine-rich domain 1. (305 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (420 aa)
PPP2R3CSerine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X2. (453 aa)
DDX39AATP-dependent RNA helicase DDX39A. (427 aa)
PABPC1LPolyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (585 aa)
EIF2AEukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (608 aa)
NXF3Nuclear RNA export factor 3-like. (546 aa)
PPP4R4Serine/threonine-protein phosphatase 4 regulatory subunit 4. (847 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (599 aa)
PAPOLGpoly(A) polymerase gamma isoform X1. (741 aa)
ZC3HAV1Poly [ADP-ribose] polymerase. (795 aa)
DDX19BATP-dependent RNA helicase DDX19B. (478 aa)
LOC109547085ATP-dependent RNA helicase DDX19A-like. (460 aa)
PAPOLAPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (742 aa)
MSI1RNA-binding protein Musashi homolog 1. (342 aa)
ENSTTRP00000005246annotation not available (623 aa)
ETF1Eukaryotic peptide chain release factor subunit 1 isoform X1. (415 aa)
SMG1Serine/threonine-protein kinase SMG1 isoform X1; Belongs to the PI3/PI4-kinase family. (3627 aa)
CPSF4LPutative cleavage and polyadenylation specificity factor subunit 4-like protein. (151 aa)
ZGRF1Protein ZGRF1. (1051 aa)
ENSTTRP00000004905annotation not available (927 aa)
NXT2NTF2-related export protein 2 isoform X1. (196 aa)
YTHDC1YTH domain-containing protein 1 isoform X2. (727 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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