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| | NRAS | NRAS proto-oncogene, GTPase. (152 aa) |
| | FCER1A | High affinity immunoglobulin epsilon receptor subunit alpha isoform X1. (261 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (487 aa) |
| | ROCK1 | Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1353 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (574 aa) |
| | SGPP1 | Sphingosine-1-phosphate phosphatase 1. (441 aa) |
| | PPP2R5E | Protein phosphatase 2 regulatory subunit B'epsilon. (467 aa) |
| | DEGS2 | Sphingolipid delta(4)-desaturase/C4-monooxygenase DES2. (322 aa) |
| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa) |
| | RAC3 | Ras-related C3 botulinum toxin substrate 1 isoform X2. (192 aa) |
| | TMIGD3 | LOW QUALITY PROTEIN: transmembrane and immunoglobulin domain containing 3. (347 aa) |
| | DEGS1 | Sphingolipid delta(4)-desaturase DES1 isoform X1. (292 aa) |
| | PLCB2 | Phosphoinositide phospholipase C. (1184 aa) |
| | PPP2CB | Protein phosphatase 2 catalytic subunit beta. (285 aa) |
| | ADAMTS19 | A disintegrin and metalloproteinase with thrombospondin motifs 19. (1190 aa) |
| | LOC101336559 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2. (90 aa) |
| | ENSTTRP00000000228 | annotation not available (57 aa) |
| | CERS3 | Ceramide synthase 3. (399 aa) |
| | ENSTTRP00000000311 | annotation not available (180 aa) |
| | PPP2R1A | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like. (589 aa) |
| | PLD2 | Phospholipase D2. (929 aa) |
| | CERS4 | Ceramide synthase 4. (393 aa) |
| | MAPK9 | Mitogen-activated protein kinase 9. (424 aa) |
| | AKT2 | RAC-beta serine/threonine-protein kinase. (481 aa) |
| | NOS3 | Nitric oxide synthase 3. (1197 aa) |
| | CERS5 | Ceramide synthase 5 isoform X1. (391 aa) |
| | RAC2 | Ras-related C3 botulinum toxin substrate 1. (192 aa) |
| | BAX | Apoptosis regulator BAX. (198 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | ENSTTRP00000014090 | annotation not available (387 aa) |
| | GAB2 | GRB2-associated-binding protein 2 isoform X1. (686 aa) |
| | SGMS1 | Phosphatidylcholine:ceramide cholinephosphotransferase 1 isoform X1. (419 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A. (439 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | MAPK14 | Mitogen-activated protein kinase 14. (360 aa) |
| | AKT1 | AKT serine/threonine kinase 1. (480 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1067 aa) |
| | PLCB4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | OPRD1 | Delta-type opioid receptor; Belongs to the G-protein coupled receptor 1 family. (368 aa) |
| | PIK3R3 | Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa) |
| | ROCK2 | Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1378 aa) |
| | KRAS | GTPase KRas. (189 aa) |
| | MAPK11 | Mitogen-activated protein kinase. (364 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (367 aa) |
| | S1PR4 | Sphingosine 1-phosphate receptor 4. (385 aa) |
| | PRKCZ | Protein kinase C zeta. (592 aa) |
| | PRKCE | Protein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa) |
| | HRAS | GTPase HRas isoform X1. (189 aa) |
| | PRKCG | Protein kinase C gamma type. (697 aa) |
| | NFKB1 | Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa) |
| | PPP2R1B | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (664 aa) |
| | ABCC1 | Multidrug resistance-associated protein 1. (1522 aa) |
| | PLCB3 | Phosphoinositide phospholipase C. (1230 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) |
| | TRADD | Tumor necrosis factor receptor type 1-associated DEATH domain protein. (262 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1. (393 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa) |
| | ADORA1 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (212 aa) |
| | MS4A2 | High affinity immunoglobulin epsilon receptor subunit beta. (242 aa) |
| | LOC101334835 | Interferon-induced transmembrane protein 3. (148 aa) |
| | GNA13 | Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (282 aa) |
| | SPTLC2 | Serine palmitoyltransferase 2 isoform X2. (448 aa) |
| | FCER1G | High affinity immunoglobulin epsilon receptor subunit gamma. (66 aa) |
| | SGPP2 | Sphingosine-1-phosphate phosphatase 2 isoform X1. (399 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (496 aa) |
| | GNAQ | Guanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa) |
| | SPTLC1 | Serine palmitoyltransferase 1 isoform X1. (473 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (657 aa) |
| | PDPK1 | 3-phosphoinositide-dependent protein kinase 1 isoform X1. (558 aa) |
| | PRKCA | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa) |
| | SGMS2 | Phosphatidylcholine:ceramide cholinephosphotransferase 2. (365 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (420 aa) |
| | PPP2R3C | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma isoform X2. (453 aa) |
| | GNAI2 | G protein subunit alpha i2. (351 aa) |
| | SGPL1 | Sphingosine-1-phosphate lyase 1. (406 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (599 aa) |
| | CERS2 | Ceramide synthase 2 isoform X1. (399 aa) |
| | ENSTTRP00000006413 | annotation not available (364 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa) |
| | GNAI1 | Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa) |
| | CERS6 | Ceramide synthase 6 isoform X1. (391 aa) |
| | ENSTTRP00000005523 | annotation not available (722 aa) |
| | MAPK3 | Mitogen-activated protein kinase 3. (382 aa) |
| | PLD1 | Phospholipase. (1074 aa) |
| | BCL2 | Apoptosis regulator Bcl-2 isoform X1. (233 aa) |
| | RAC1 | Ras-related C3 botulinum toxin substrate 1 isoform X1. (199 aa) |
| | S1PR1 | Sphingosine 1-phosphate receptor 1 isoform X2; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | ERAS | ES cell expressed Ras. (233 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (531 aa) |
| | LOC101323346 | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta. (491 aa) |
| | SMPD2 | Sphingomyelin phosphodiesterase 2. (423 aa) |
| | SPTLC3 | Serine palmitoyltransferase 3 isoform X1. (548 aa) |
| | GNA12 | Guanine nucleotide-binding protein subunit alpha-12. (382 aa) |
| | NSMAF | Protein FAN isoform X4. (897 aa) |
| | BDKRB2 | B2 bradykinin receptor; Belongs to the G-protein coupled receptor 1 family. (392 aa) |
| | ASAH1 | Acid ceramidase isoform X8; Belongs to the acid ceramidase family. (403 aa) |
| | ASAH2 | Neutral ceramidase. (666 aa) |
| | S1PR2 | Sphingosine-1-phosphate receptor 2. (352 aa) |
| | PPP2R3A | Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1. (1147 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1049 aa) |
| | PRKCB | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa) |
| | TRAF2 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (504 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 isoform X2. (1362 aa) |
| | ADAMTS17 | A disintegrin and metalloproteinase with thrombospondin motifs 17 isoform X2. (1089 aa) |
| | ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (505 aa) |
| | RHOA | Transforming protein RhoA. (193 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase. (309 aa) |
| | KNG1 | Kininogen-1 isoform X1. (627 aa) |
| | MAPK1 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa) |
| | ENSTTRP00000015784 | annotation not available (149 aa) |
| | ENSTTRP00000015457 | annotation not available (403 aa) |
| | ENSTTRP00000015396 | annotation not available (256 aa) |
| | PTK6 | Tyrosine-protein kinase. (425 aa) |
| | PIK3R1 | Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (732 aa) |
| | PPP2R2C | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (423 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (463 aa) |
| | PPP2R2B | Protein phosphatase 2 regulatory subunit Bbeta. (509 aa) |
| | ENSTTRP00000015100 | annotation not available (189 aa) |
| | SPHK1 | Sphingosine kinase 1 isoform X2. (473 aa) |
| | CSDE1 | Cold shock domain-containing protein E1. (813 aa) |
