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| | ANAPC5 | Anaphase-promoting complex subunit 5 isoform X1. (754 aa) |
| | CUL1 | Cullin-1; Belongs to the cullin family. (767 aa) |
| | CCND1 | G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa) |
| | MCM2 | Minichromosome maintenance complex component 2. (905 aa) |
| | CREBBP | CREB-binding protein isoform X6. (2402 aa) |
| | CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (499 aa) |
| | SKP1 | S-phase kinase-associated protein 1; Belongs to the SKP1 family. (163 aa) |
| | SFN | Stratifin. (248 aa) |
| | GSK3B | Glycogen synthase kinase-3 beta isoform X2; Belongs to the protein kinase superfamily. (433 aa) |
| | PKMYT1 | Protein kinase, membrane associated tyrosine/threonine 1. (499 aa) |
| | YWHAE | 14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa) |
| | ENSTTRP00000015677 | annotation not available (289 aa) |
| | ANAPC1 | Anaphase-promoting complex subunit 1 isoform X1. (1943 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa) |
| | BUB3 | Mitotic checkpoint protein BUB3 isoform X1. (328 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (828 aa) |
| | E2F2 | Transcription factor E2F2 isoform X1. (433 aa) |
| | CDC25A | M-phase inducer phosphatase 1 isoform X1. (523 aa) |
| | YWHAZ | 14-3-3 protein zeta/delta isoform X1; Belongs to the 14-3-3 family. (245 aa) |
| | CDK3 | Cyclin dependent kinase 3. (304 aa) |
| | MDM2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (495 aa) |
| | ZBTB17 | Zinc finger and BTB domain-containing protein 17. (699 aa) |
| | CCNH | cyclin-H; Belongs to the cyclin family. (323 aa) |
| | CDC16 | Cell division cycle protein 16 homolog isoform X1. (620 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (187 aa) |
| | WEE1 | Wee1-like protein kinase. (646 aa) |
| | CDC14A | Dual specificity protein phosphatase CDC14A isoform X1. (622 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa) |
| | ABL1 | Tyrosine-protein kinase. (1148 aa) |
| | ANAPC7 | LOW QUALITY PROTEIN: anaphase-promoting complex subunit 7. (564 aa) |
| | GADD45A | Growth arrest and DNA damage-inducible protein GADD45 alpha isoform X1. (165 aa) |
| | HDAC2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (583 aa) |
| | CDKN1B | Cyclin-dependent kinase inhibitor 1B. (173 aa) |
| | CDK2 | Cyclin dependent kinase 2. (298 aa) |
| | CDC45 | Cell division control protein 45 homolog. (567 aa) |
| | YWHAG | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma. (238 aa) |
| | BUB1B | Mitotic checkpoint serine/threonine-protein kinase BUB1 beta isoform X1. (1051 aa) |
| | LOC109549807 | LOW QUALITY PROTEIN: uncharacterized protein LOC109549807. (169 aa) |
| | CDKN2B | Cyclin-dependent kinase 4 inhibitor B. (86 aa) |
| | CHEK1 | Serine/threonine-protein kinase Chk1 isoform X1; Belongs to the protein kinase superfamily. (475 aa) |
| | YWHAQ | 14-3-3 protein theta; Belongs to the 14-3-3 family. (242 aa) |
| | SMC1B | Structural maintenance of chromosomes protein. (1197 aa) |
| | CDK1 | Cyclin-dependent kinase 1 isoform X3; Belongs to the protein kinase superfamily. (301 aa) |
| | CCNA2 | cyclin-A2; Belongs to the cyclin family. (431 aa) |
| | HDAC1 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (428 aa) |
| | MYNN | Myoneurin isoform X2. (608 aa) |
| | RBL1 | Retinoblastoma-like protein 1 isoform X2. (1067 aa) |
| | RAD21 | Double-strand-break repair protein rad21 homolog isoform X1. (630 aa) |
| | STAG2 | Cohesin subunit SA-2 isoform X1. (1268 aa) |
| | ANAPC13 | Anaphase-promoting complex subunit 13. (40 aa) |
| | ANAPC2 | Anaphase-promoting complex subunit 2; Belongs to the cullin family. (816 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | SNPH | Syntaphilin isoform X1. (478 aa) |
| | ESPL1 | Extra spindle pole bodies like 1, separase. (2106 aa) |
| | CCNB1 | G2/mitotic-specific cyclin-B1; Belongs to the cyclin family. (433 aa) |
| | CDK7 | Cyclin-dependent kinase 7 isoform X1; Belongs to the protein kinase superfamily. (346 aa) |
| | TTK | Dual specificity protein kinase TTK isoform X1. (856 aa) |
| | ANAPC4 | Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family. (808 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog 3. (291 aa) |
| | BUB1 | Mitotic checkpoint serine/threonine-protein kinase BUB1 isoform X1. (1083 aa) |
| | CDC26 | Anaphase-promoting complex subunit CDC26 isoform X2. (85 aa) |
| | EP300 | Histone acetyltransferase p300. (2422 aa) |
| | GADD45G | Growth arrest and DNA damage inducible gamma. (159 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (820 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (801 aa) |
| | CCNA1 | cyclin-A1 isoform X1; Belongs to the cyclin family. (464 aa) |
| | RB1 | Retinoblastoma-associated protein. (922 aa) |
| | TFDP1 | Transcription factor. (410 aa) |
| | CCNE2 | G1/S-specific cyclin-E2; Belongs to the cyclin family. (404 aa) |
| | ZNF652 | Zinc finger protein 652 isoform X1. (606 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (602 aa) |
| | CCNB2 | G2/mitotic-specific cyclin-B2 isoform X1; Belongs to the cyclin family. (371 aa) |
| | CDC23 | Cell division cycle protein 23 homolog. (597 aa) |
| | CDC25C | M-phase inducer phosphatase 3 isoform X2. (475 aa) |
| | CDC14B | Dual specificity protein phosphatase CDC14B isoform X2. (498 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3043 aa) |
| | CDC7 | Cell division cycle 7-related protein kinase. (572 aa) |
| | DBF4 | Protein DBF4 homolog A isoform X1. (675 aa) |
| | GADD45B | Growth arrest and DNA damage inducible beta. (160 aa) |
| | MCM5 | DNA replication licensing factor MCM5-like. (734 aa) |
| | YWHAB | 14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (246 aa) |
| | FAM126B | Protein FAM126B isoform X3. (530 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1215 aa) |
| | CDKN2D | Cyclin-dependent kinase 4 inhibitor D. (161 aa) |
| | CCNE1 | G1/S-specific cyclin-E1; Belongs to the cyclin family. (350 aa) |
| | SKP2 | S-phase kinase-associated protein 2 isoform X2. (441 aa) |
| | PRKDC | DNA-dependent protein kinase catalytic subunit-like isoform X2; Belongs to the PI3/PI4-kinase family. (4120 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (692 aa) |
| | CDK4 | Cyclin-dependent kinase 4 isoform X1; Belongs to the protein kinase superfamily. (254 aa) |
| | CDK20 | Cyclin-dependent kinase 20-like. (409 aa) |
| | CDC20B | Cell division cycle protein 20 homolog B. (519 aa) |
| | FZR1 | Fizzy-related protein homolog. (494 aa) |
| | ORC3 | Origin recognition complex subunit 3 isoform X3. (714 aa) |
| | E2F3 | Transcription factor E2F3. (334 aa) |
| | CDKN2C | Cyclin-dependent kinase 4 inhibitor C. (168 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (88 aa) |
| | CCND3 | Cyclin D3. (225 aa) |
| | CDC25B | Cell division cycle 25B. (568 aa) |
| | CDKN1C | Cyclin-dependent kinase inhibitor 1C. (249 aa) |
| | ZBTB47 | Zinc finger protein 652 isoform X3. (615 aa) |
| | WEE2 | Wee1-like protein kinase. (569 aa) |
| | ATR | Serine/threonine-protein kinase ATR isoform X2; Belongs to the PI3/PI4-kinase family. (2623 aa) |
| | MAD2L2 | Mitotic spindle assembly checkpoint protein MAD2B. (223 aa) |
| | E2F1 | Transcription factor E2F1 isoform X1. (437 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (387 aa) |
| | E2F4 | LOW QUALITY PROTEIN: transcription factor E2F4. (398 aa) |
| | YWHAH | 14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa) |
| | CCNB3 | Cyclin B3. (1237 aa) |
| | STAG1 | Cohesin subunit SA-1 isoform X1. (1258 aa) |
| | MAD1L1 | Mitotic spindle assembly checkpoint protein MAD1 isoform X1. (755 aa) |
| | ORC5 | Origin recognition complex subunit 5 isoform X1. (376 aa) |
| | CDC20 | LOW QUALITY PROTEIN: cell division cycle protein 20 homolog. (499 aa) |
| | MAD2L1 | Mitotic spindle assembly checkpoint protein MAD2A. (205 aa) |
| | CDK6 | Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1233 aa) |
| | TMEM82 | Transmembrane protein 82. (341 aa) |
| | ZBTB10 | Zinc finger and BTB domain-containing protein 10. (523 aa) |
| | PTTG1 | Securin isoform X1. (202 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (407 aa) |
| | ORC2 | Origin recognition complex subunit 2 isoform X1. (496 aa) |
| | CHEK2 | Serine/threonine-protein kinase Chk2 isoform X2. (580 aa) |
| | RBX1 | E3 ubiquitin-protein ligase RBX1. (82 aa) |
| | TFDP2 | Transcription factor. (445 aa) |
| | E2F5 | Transcription factor E2F5 isoform X2. (340 aa) |
| | ANAPC10 | Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. (185 aa) |
| | ZBTB46 | Zinc finger and BTB domain-containing protein 46. (466 aa) |
| | ANAPC11 | Anaphase-promoting complex subunit 11. (193 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (718 aa) |
| | RBL2 | Retinoblastoma-like protein 2. (1140 aa) |
| | TGFB1 | Transforming growth factor beta 1. (338 aa) |
| | ORC6 | Origin recognition complex subunit 6. (252 aa) |
| | CDKN1A | Cyclin-dependent kinase inhibitor 1. (164 aa) |
| | CDC27 | Cell division cycle protein 27 homolog isoform X3. (824 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa) |
