32 items (Tursiops truncatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PIK3C3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (885 aa)
	ATG13	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (552 aa)
	PPP2CB	Protein phosphatase 2 catalytic subunit beta. (285 aa)
	RPTOR	Regulatory-associated protein of mTOR-like. (1324 aa)
	ATG12	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (185 aa)
	ATG9B	Autophagy related 9B. (895 aa)
	IGBP1	Immunoglobulin-binding protein 1 isoform X1. (338 aa)
	GABARAPL2	Gamma-aminobutyric acid receptor-associated protein-like 2. (117 aa)
	MTOR	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2442 aa)
	PIK3R4	Phosphoinositide 3-kinase regulatory subunit 4 isoform X1. (1357 aa)
	ATG101	Autophagy-related protein 101. (218 aa)
	ATG3	Autophagy-related protein 3. (290 aa)
	ATG2B	Autophagy-related protein 2 homolog B isoform X5. (2021 aa)
	WIPI2	WD repeat domain phosphoinositide-interacting protein 2 isoform X1. (416 aa)
	ULK2	Serine/threonine-protein kinase ULK2 isoform X2. (1033 aa)
	ULK3	Serine/threonine-protein kinase ULK3 isoform X2; Belongs to the protein kinase superfamily. (214 aa)
	ENSTTRP00000007761	annotation not available (312 aa)
	ATG2A	Autophagy-related protein 2 homolog A isoform X1. (1932 aa)
	GABARAPL1	Gamma-aminobutyric acid receptor-associated protein-like 1. (117 aa)
	GABARAP	GABA type A receptor-associated protein. (80 aa)
	ATG4A	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (425 aa)
	ATG9A	Autophagy-related protein 9A isoform X1. (899 aa)
	BECN1	Beclin-1 isoform X2. (448 aa)
	WIPI1	WD repeat domain phosphoinositide-interacting protein 1 isoform X4. (387 aa)
	ATG5	Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
	ATG10	Ubiquitin-like-conjugating enzyme ATG10 isoform X1. (221 aa)
	ATG4C	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa)
	TTC14	Tetratricopeptide repeat protein 14 isoform X1. (771 aa)
	ATG16L1	Autophagy-related protein 16-1 isoform X1. (624 aa)
	ATG7	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (702 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	ATG4B	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (376 aa)

Your Current Organism:

Tursiops truncatus

NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATG10	ATG101	ENSTTRP00000012985	ENSTTRP00000002641	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Autophagy-related protein 101.	0.664
ATG10	ATG12	ENSTTRP00000012985	ENSTTRP00000000765	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family.	0.994
ATG10	ATG13	ENSTTRP00000012985	ENSTTRP00000000419	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily.	0.748
ATG10	ATG16L1	ENSTTRP00000012985	ENSTTRP00000015450	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Autophagy-related protein 16-1 isoform X1.	0.777
ATG10	ATG2A	ENSTTRP00000012985	ENSTTRP00000008433	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Autophagy-related protein 2 homolog A isoform X1.	0.541
ATG10	ATG2B	ENSTTRP00000012985	ENSTTRP00000004655	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Autophagy-related protein 2 homolog B isoform X5.	0.533
ATG10	ATG3	ENSTTRP00000012985	ENSTTRP00000004092	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Autophagy-related protein 3.	0.791
ATG10	ATG4A	ENSTTRP00000012985	ENSTTRP00000009510	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.740
ATG10	ATG4B	ENSTTRP00000012985	ENSTTRP00000016381	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.730
ATG10	ATG4C	ENSTTRP00000012985	ENSTTRP00000013192	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family.	0.693
ATG10	ATG5	ENSTTRP00000012985	ENSTTRP00000012078	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Autophagy protein 5; Involved in autophagic vesicle formation.	0.897
ATG10	ATG7	ENSTTRP00000012985	ENSTTRP00000015699	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]	0.981
ATG10	ATG9A	ENSTTRP00000012985	ENSTTRP00000009516	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Autophagy-related protein 9A isoform X1.	0.638
ATG10	ATG9B	ENSTTRP00000012985	ENSTTRP00000000793	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Autophagy related 9B.	0.537
ATG10	BECN1	ENSTTRP00000012985	ENSTTRP00000011116	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Beclin-1 isoform X2.	0.680
ATG10	GABARAP	ENSTTRP00000012985	ENSTTRP00000009258	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	GABA type A receptor-associated protein.	0.496
ATG10	GABARAPL1	ENSTTRP00000012985	ENSTTRP00000008604	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Gamma-aminobutyric acid receptor-associated protein-like 1.	0.496
ATG10	GABARAPL2	ENSTTRP00000012985	ENSTTRP00000001145	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Gamma-aminobutyric acid receptor-associated protein-like 2.	0.600
ATG10	PIK3C3	ENSTTRP00000012985	ENSTTRP00000000105	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Phosphatidylinositol 3-kinase catalytic subunit type 3.	0.493
ATG10	PIK3R4	ENSTTRP00000012985	ENSTTRP00000002386	Ubiquitin-like-conjugating enzyme ATG10 isoform X1.	Phosphoinositide 3-kinase regulatory subunit 4 isoform X1.	0.493