STRINGSTRING
KCNMB2 KCNMB2 MYH10 MYH10 ENSTTRP00000006413 ENSTTRP00000006413 ETV3 ETV3 ETV3L ETV3L ITPR3 ITPR3 LOC101331987 LOC101331987 ACTG2 ACTG2 ADM ADM PLA2G5 PLA2G5 MYLK2 MYLK2 PRKCA PRKCA PPP1CB PPP1CB ARHGEF1 ARHGEF1 ERF ERF ADCY4 ADCY4 GNAQ GNAQ NPPC NPPC GNA13 GNA13 ENSTTRP00000008884 ENSTTRP00000008884 EDN3 EDN3 AGTR1 AGTR1 PPP1R14A PPP1R14A PLCB1 PLCB1 PLA2G12B PLA2G12B RAMP3 RAMP3 ADRA1D ADRA1D ARAF ARAF ENSTTRP00000009532 ENSTTRP00000009532 MAP2K1 MAP2K1 PLA2G3 PLA2G3 MYH11 MYH11 PLCB3 PLCB3 PPP1R12A PPP1R12A LOC101315484 LOC101315484 PRKCG PRKCG CALML6 CALML6 PPP1R12B PPP1R12B ADCY6 ADCY6 PRKACB PRKACB NPPA NPPA NPPB NPPB RAMP2 RAMP2 ARHGEF12 ARHGEF12 PRKCE PRKCE CALCB CALCB NPR2 NPR2 ENSTTRP00000011347 ENSTTRP00000011347 CALM2 CALM2 CACNA1D CACNA1D GNA11 GNA11 ESYT2 ESYT2 ADRA1B ADRA1B ROCK2 ROCK2 PRKCQ PRKCQ PPP1CA PPP1CA MYLK3 MYLK3 ADCY1 ADCY1 ADCY7 ADCY7 ADCY8 ADCY8 CALM1 CALM1 GUCY1A2 GUCY1A2 CACNA1S CACNA1S CALCRL CALCRL PRKCH PRKCH PLCB4 PLCB4 KCNMB3 KCNMB3 MYH9 MYH9 ITPR1 ITPR1 ENSTTRP00000013721 ENSTTRP00000013721 ARHGEF11 ARHGEF11 PRKACA PRKACA PLCB2 PLCB2 LOC101332449 LOC101332449 RAMP1 RAMP1 ADORA2A ADORA2A ADCY5 ADCY5 MYLK MYLK GUCY1A1 GUCY1A1 GUCY1B1 GUCY1B1 MYL9 MYL9 AVPR1A AVPR1A KCNU1 KCNU1 ADORA2B ADORA2B KCNMB1 KCNMB1 KCNMA1 KCNMA1 PRKCD PRKCD MYH14 MYH14 EDNRA EDNRA BRAF BRAF LOC101320351 LOC101320351 PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F ENSTTRP00000002457 ENSTTRP00000002457 PRKCB PRKCB ADCY9 ADCY9 PLA2G10 PLA2G10 CACNA1C CACNA1C CALD1 CALD1 CALM3 CALM3 PRKG1 PRKG1 ITPR2 ITPR2 GNA12 GNA12 LYVE1 LYVE1 MYLK4 MYLK4 MRVI1 MRVI1 AGT AGT PLA2G2E PLA2G2E ADCY2 ADCY2 PROCA1 PROCA1 ACTA2 ACTA2 RHOA RHOA PLA2G2C PLA2G2C PLA2G2D PLA2G2D CACNA1F CACNA1F MAPK1 MAPK1 PLA2G4A PLA2G4A LOC101323342 LOC101323342 MYL6 MYL6 MYL6B MYL6B ESYT1 ESYT1 PLA2G12A PLA2G12A CALML4 CALML4 GNAS GNAS PPP1R12C PPP1R12C AVPR1B AVPR1B ROCK1 ROCK1 ADCY3 ADCY3 PTRHD1 PTRHD1 PPP1CC PPP1CC NPR1 NPR1 ADRA1A ADRA1A KCNMB4 KCNMB4 MAPK3 MAPK3 EDN2 EDN2 PLA2G6 PLA2G6 PLA2G1B PLA2G1B ENSTTRP00000005432 ENSTTRP00000005432 ENSTTRP00000005443 ENSTTRP00000005443 ENSTTRP00000005447 ENSTTRP00000005447 EDN1 EDN1 ESYT3 ESYT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNMB2Calcium-activated potassium channel subunit beta-2. (235 aa)
MYH10Myosin-10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2004 aa)
ENSTTRP00000006413annotation not available (364 aa)
ETV3ETS translocation variant 3 isoform X2. (511 aa)
ETV3LETS variant transcription factor 3 like. (355 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3-like. (2669 aa)
LOC101331987Calcitonin receptor-stimulating peptide 2-like. (72 aa)
ACTG2Actin, gamma-enteric smooth muscle. (376 aa)
ADMADM. (185 aa)
PLA2G5Phospholipase A(2). (124 aa)
MYLK2Myosin light chain kinase 2. (597 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (367 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (838 aa)
ERFETS2 repressor factor. (549 aa)
ADCY4Adenylate cyclase type 4; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1077 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
NPPCNatriuretic peptide C. (126 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (282 aa)
ENSTTRP00000008884annotation not available (287 aa)
EDN3Endothelin-3. (213 aa)
AGTR1Type-1 Angiotensin II receptor; Belongs to the G-protein coupled receptor 1 family. (359 aa)
PPP1R14AProtein phosphatase 1 regulatory subunit 14A. (105 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
PLA2G12BGroup XIIB secretory phospholipase A2-like protein isoform X1. (195 aa)
RAMP3Receptor activity-modifying protein 3. (151 aa)
ADRA1Dalpha-1D adrenergic receptor. (569 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform X1. (609 aa)
ENSTTRP00000009532annotation not available (73 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (393 aa)
PLA2G3Phospholipase A2 group III. (505 aa)
MYH11Myosin-11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1975 aa)
PLCB3Phosphoinositide phospholipase C. (1230 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
LOC101315484LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like. (613 aa)
PRKCGProtein kinase C gamma type. (697 aa)
CALML6Calmodulin-like protein 6. (179 aa)
PPP1R12BProtein phosphatase 1 regulatory subunit. (976 aa)
ADCY6Adenylate cyclase 6. (1167 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
NPPAAtrial natriuretic peptide. (177 aa)
NPPBNatriuretic peptides B. (127 aa)
RAMP2Receptor activity modifying protein 2. (176 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12 isoform X1. (1542 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (736 aa)
CALCBCalcitonin gene-related peptide 2 isoform X2. (125 aa)
NPR2Guanylate cyclase. (1047 aa)
ENSTTRP00000011347annotation not available (185 aa)
CALM2Calmodulin 2. (148 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
GNA11G protein subunit alpha 11. (359 aa)
ESYT2Extended synaptotagmin-2 isoform X4. (884 aa)
ADRA1Balpha-1B adrenergic receptor. (395 aa)
ROCK2Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1378 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
PPP1CAProtein phosphatase 1 catalytic subunit alpha. (321 aa)
MYLK3Myosin light chain kinase 3. (800 aa)
ADCY1Adenylate cyclase 1. (1088 aa)
ADCY7Adenylate cyclase type 7-like. (1080 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
CALM1Calmodulin; Belongs to the calmodulin family. (149 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (749 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha-1S-like. (1856 aa)
CALCRLCalcitonin gene-related peptide type 1 receptor; Belongs to the G-protein coupled receptor 2 family. (461 aa)
PRKCHProtein kinase C eta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction integrity and foam cell formation, and is required for glioblastoma proliferation and apoptosis prevention in MCF-7 cells. In keratinocytes, binds and activates the tyrosine kinase FYN, which in turn blocks epidermal growth factor receptor (EGFR) signaling and leads to keratinocyte growth arrest and differentia [...] (635 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
KCNMB3LOW QUALITY PROTEIN: calcium-activated potassium channel subunit beta-3. (271 aa)
MYH9Myosin-9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1885 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2752 aa)
ENSTTRP00000013721annotation not available (118 aa)
ARHGEF11Rho guanine nucleotide exchange factor 11 isoform X2. (1548 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (351 aa)
PLCB2Phosphoinositide phospholipase C. (1184 aa)
LOC101332449Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (318 aa)
RAMP1Receptor activity-modifying protein 1. (130 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (411 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
MYLKMyosin light chain kinase. (1911 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (684 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (610 aa)
MYL9Myosin regulatory light polypeptide 9. (172 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
KCNU1Potassium channel subfamily U member 1. (956 aa)
ADORA2BAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (315 aa)
KCNMB1Calcium-activated potassium channel subunit beta-1. (191 aa)
KCNMA1Calcium-activated potassium channel subunit alpha-1 isoform X1. (1173 aa)
PRKCDProtein kinase C delta. (671 aa)
MYH14Myosin heavy chain 14. (1933 aa)
EDNRAEndothelin-1 receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X4. (757 aa)
LOC101320351Cytosolic phospholipase A2 beta isoform X1. (1010 aa)
PLA2G4ECytosolic phospholipase A2 epsilon. (858 aa)
PLA2G4DPhospholipase A2. (817 aa)
PLA2G4FCytosolic phospholipase A2 zeta. (848 aa)
ENSTTRP00000002457annotation not available (138 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1226 aa)
PLA2G10Phospholipase A(2). (128 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha-1C-like. (2195 aa)
CALD1Caldesmon isoform X14. (744 aa)
CALM3Calmodulin 3. (148 aa)
PRKG1cGMP-dependent protein kinase 1; Belongs to the protein kinase superfamily. (686 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2697 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (382 aa)
LYVE1Lymphatic vessel endothelial hyaluronic acid receptor 1 isoform X1. (320 aa)
MYLK4Myosin light chain kinase family member 4. (388 aa)
MRVI1Murine retrovirus integration site 1 homolog. (885 aa)
AGTAngiotensinogen; Belongs to the serpin family. (484 aa)
PLA2G2EPhospholipase A(2). (142 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
PROCA1Protein interacting with cyclin A1. (333 aa)
ACTA2Actin, aortic smooth muscle. (378 aa)
RHOATransforming protein RhoA. (193 aa)
PLA2G2CPhospholipase A2 group IIC. (143 aa)
PLA2G2DPhospholipase A2 group IID. (142 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha-1F isoform X1. (1973 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa)
PLA2G4APhospholipase A2. (748 aa)
LOC101323342Calcitonin receptor-stimulating peptide 1-like. (74 aa)
MYL6Myosin light chain 6. (151 aa)
MYL6BMyosin light chain 6B. (207 aa)
ESYT1Extended synaptotagmin-1 isoform X3. (1106 aa)
PLA2G12AGroup XIIA secretory phospholipase A2. (182 aa)
CALML4Calmodulin-like protein 4 isoform X2. (195 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
PPP1R12CProtein phosphatase 1 regulatory subunit 12C. (780 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (355 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1353 aa)
ADCY3Adenylate cyclase type 3. (1141 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (139 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (293 aa)
NPR1Natriuretic peptide receptor 1. (1055 aa)
ADRA1Aalpha-1A adrenergic receptor. (423 aa)
KCNMB4Calcium-activated potassium channel subunit beta-4. (206 aa)
MAPK3Mitogen-activated protein kinase 3. (382 aa)
EDN2Endothelin-2. (180 aa)
PLA2G685/88 kDa calcium-independent phospholipase A2 isoform X2. (784 aa)
PLA2G1BPhospholipase A(2). (148 aa)
ENSTTRP00000005432annotation not available (287 aa)
ENSTTRP00000005443annotation not available (370 aa)
ENSTTRP00000005447annotation not available (519 aa)
EDN1Endothelin-1. (202 aa)
ESYT3Extended synaptotagmin-3 isoform X1. (775 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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