STRINGSTRING
PAK6 PAK6 RGMA RGMA EPHA4 EPHA4 EPHA3 EPHA3 PPP3CB PPP3CB CDK5 CDK5 CAMK2D CAMK2D RAC2 RAC2 SEMA3A SEMA3A SEMA3G SEMA3G MYL9 MYL9 SEMA4A SEMA4A GNAI3 GNAI3 RAC3 RAC3 TRPC3 TRPC3 EPHA6 EPHA6 SEMA6B SEMA6B TRPC6 TRPC6 RHOD RHOD SSH3 SSH3 PLXNA1 PLXNA1 PARD6G PARD6G EPHA8 EPHA8 EPHB2 EPHB2 PLCG1 PLCG1 PPP3CA PPP3CA CCDC125 CCDC125 MYL5 MYL5 PIK3CD PIK3CD SEMA4D SEMA4D TRPC4 TRPC4 NTN4 NTN4 RYK RYK ABLIM2 ABLIM2 LDAH LDAH SLIT3 SLIT3 SSH1 SSH1 NTNG1 NTNG1 SRGAP1 SRGAP1 RND1 RND1 ERAS ERAS DPYSL2 DPYSL2 ILK ILK SEMA6A SEMA6A SEMA5A SEMA5A BMPR2 BMPR2 RAC1 RAC1 SEMA3E SEMA3E WNT5A WNT5A RRAS RRAS MAPK3 MAPK3 EPHA5 EPHA5 SRC SRC CDC42 CDC42 WNT4 WNT4 SLIT2 SLIT2 BOC BOC ENSTTRP00000005523 ENSTTRP00000005523 FZD3 FZD3 EFNB1 EFNB1 LRRC4 LRRC4 UNC5D UNC5D GNAI1 GNAI1 PIK3CB PIK3CB MET MET PLCG2 PLCG2 EFNB2 EFNB2 SEMA6C SEMA6C ENSTTRP00000007008 ENSTTRP00000007008 L1CAM L1CAM SEMA3F SEMA3F GNAI2 GNAI2 SEMA3B SEMA3B NFATC2 NFATC2 EPHB6 EPHB6 SEMA4C SEMA4C FES FES CAMK2B CAMK2B SEMA7A SEMA7A PRKCA PRKCA MYL12A MYL12A MYL12B MYL12B ABLIM3 ABLIM3 CXCL12 CXCL12 SMO SMO EPHA10 EPHA10 NFATC4 NFATC4 LIMK1 LIMK1 SEMA3C SEMA3C PAK1 PAK1 PARD3 PARD3 PTPN11 PTPN11 PARD6A PARD6A ROBO1 ROBO1 SRGAP2 SRGAP2 SEMA3D SEMA3D SRGAP3 SRGAP3 PTK2 PTK2 ROBO2 ROBO2 SLIT1 SLIT1 EFNA5 EFNA5 ITGB1 ITGB1 NRP1 NRP1 TRPC1 TRPC1 EFNB3 EFNB3 LIMK2 LIMK2 DPYSL5 DPYSL5 EPHB1 EPHB1 EPHA1 EPHA1 PTCH1 PTCH1 NGEF NGEF EFNA2 EFNA2 EPHB4 EPHB4 HRAS HRAS PLXNA3 PLXNA3 PDK1 PDK1 ARHGEF12 ARHGEF12 PLXNB3 PLXNB3 SEMA5B SEMA5B NCK1 NCK1 PRKCZ PRKCZ PLXNC1 PLXNC1 CAMK2G CAMK2G NTNG2 NTNG2 UNC5A UNC5A PLXNB2 PLXNB2 KRAS KRAS PLXNA2 PLXNA2 PPP3CC PPP3CC SEMA4F SEMA4F PAK3 PAK3 ROCK2 ROCK2 PIK3R3 PIK3R3 ENSTTRP00000012558 ENSTTRP00000012558 ROBO3 ROBO3 EPHB3 EPHB3 NCK2 NCK2 ABLIM1 ABLIM1 SHH SHH RGS3 RGS3 PAK2 PAK2 PAK5 PAK5 PIK3CA PIK3CA PARD6B PARD6B FYN FYN NFATC3 NFATC3 CAMK2A CAMK2A ARSI ARSI ENAH ENAH PAK4 PAK4 BMPR1B BMPR1B UNC5C UNC5C SEMA4G SEMA4G ABL1 ABL1 ROCK1 ROCK1 NRAS NRAS CSDE1 CSDE1 RASA1 RASA1 DCC DCC BMP7 BMP7 NEO1 NEO1 SEMA6D SEMA6D TRPC5 TRPC5 EPHA7 EPHA7 SEMA4B SEMA4B EFNA1 EFNA1 EFNA3 EFNA3 EFNA4 EFNA4 ADAM15 ADAM15 PIK3R1 PIK3R1 PTK6 PTK6 ENSTTRP00000015396 ENSTTRP00000015396 TRPC7 TRPC7 SSH2 SSH2 NTN1 NTN1 ENSTTRP00000015784 ENSTTRP00000015784 GSK3B GSK3B MAPK1 MAPK1 CFL1 CFL1 UNC5B UNC5B WNT5B WNT5B PLXNB1 PLXNB1 RHOA RHOA EPHA2 EPHA2 PLXNA4 PLXNA4 ENSTTRP00000016529 ENSTTRP00000016529
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAK6P21 (RAC1) activated kinase 6. (675 aa)
RGMARepulsive guidance molecule A isoform X1. (450 aa)
EPHA4Ephrin type-A receptor 4 isoform X1. (979 aa)
EPHA3Ephrin type-A receptor 3 isoform X1. (984 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
CDK5Cyclin dependent kinase 5. (292 aa)
CAMK2DCalcium/calmodulin-dependent protein kinase type II subunit delta isoform X4; Belongs to the protein kinase superfamily. (498 aa)
RAC2Ras-related C3 botulinum toxin substrate 1. (192 aa)
SEMA3Asemaphorin-3A; Belongs to the semaphorin family. (772 aa)
SEMA3GSemaphorin 3G. (765 aa)
MYL9Myosin regulatory light polypeptide 9. (172 aa)
SEMA4Asemaphorin-4A; Belongs to the semaphorin family. (762 aa)
GNAI3G protein subunit alpha i3. (354 aa)
RAC3Ras-related C3 botulinum toxin substrate 1 isoform X2. (192 aa)
TRPC3Short transient receptor potential channel 3 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (914 aa)
EPHA6Ephrin type-A receptor 6. (1011 aa)
SEMA6Bsemaphorin-6B-like. (677 aa)
TRPC6Short transient receptor potential channel 6; Belongs to the transient receptor (TC 1.A.4) family. (930 aa)
RHODRas homolog family member D. (208 aa)
SSH3Protein phosphatase Slingshot homolog 3. (644 aa)
PLXNA1plexin-A1. (1889 aa)
PARD6GPartitioning defective 6 homolog gamma. (367 aa)
EPHA8EPH receptor A8. (1001 aa)
EPHB2Ephrin type-B receptor 2. (1031 aa)
PLCG1Phosphoinositide phospholipase C. (1290 aa)
PPP3CASerine/threonine-protein phosphatase. (560 aa)
CCDC125Coiled-coil domain-containing protein 125 isoform X1. (512 aa)
MYL5Myosin light chain 5. (178 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1049 aa)
SEMA4Dsemaphorin-4D isoform X1; Belongs to the semaphorin family. (863 aa)
TRPC4Short transient receptor potential channel 4 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (982 aa)
NTN4Netrin-4 isoform X1. (628 aa)
RYKTyrosine-protein kinase RYK isoform X2. (559 aa)
ABLIM2Uncharacterized protein LOC109552769. (644 aa)
LDAHLipid droplet-associated hydrolase isoform X1. (315 aa)
SLIT3Slit homolog 3 protein. (1521 aa)
SSH1Protein phosphatase Slingshot homolog 1 isoform X1. (998 aa)
NTNG1netrin-G1 isoform X1. (538 aa)
SRGAP1SLIT-ROBO Rho GTPase-activating protein 1 isoform X1. (1085 aa)
RND1Rho-related GTP-binding protein Rho6. (231 aa)
ERASES cell expressed Ras. (233 aa)
DPYSL2Dihydropyrimidinase-related protein 2. (571 aa)
ILKIntegrin-linked protein kinase. (450 aa)
SEMA6Asemaphorin-6A isoform X1; Belongs to the semaphorin family. (1032 aa)
SEMA5Asemaphorin-5A. (1073 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (199 aa)
SEMA3Esemaphorin-3E; Belongs to the semaphorin family. (775 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
RRASRAS related. (218 aa)
MAPK3Mitogen-activated protein kinase 3. (382 aa)
EPHA5Ephrin type-A receptor 5. (1036 aa)
SRCProto-oncogene tyrosine-protein kinase Src. (538 aa)
CDC42Cell division control protein 42 homolog. (156 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
SLIT2Slit homolog 2 protein isoform X2. (1470 aa)
BOCBrother of CDO. (1116 aa)
ENSTTRP00000005523annotation not available (722 aa)
FZD3Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
EFNB1Ephrin B1. (346 aa)
LRRC4Leucine-rich repeat-containing protein 4. (652 aa)
UNC5DNetrin receptor UNC5D. (951 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
METHepatocyte growth factor receptor isoform X1. (1403 aa)
PLCG2Phosphoinositide phospholipase C. (1264 aa)
EFNB2ephrin-B2; Belongs to the ephrin family. (333 aa)
SEMA6CSemaphorin 6C. (966 aa)
ENSTTRP00000007008annotation not available (158 aa)
L1CAML1 cell adhesion molecule. (1252 aa)
SEMA3FSemaphorin 3F. (784 aa)
GNAI2G protein subunit alpha i2. (351 aa)
SEMA3Bsemaphorin-3B; Belongs to the semaphorin family. (747 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X2. (919 aa)
EPHB6Ephrin type-B receptor 6. (1016 aa)
SEMA4Csemaphorin-4C. (833 aa)
FESTyrosine-protein kinase Fes/Fps. (815 aa)
CAMK2BCalcium/calmodulin dependent protein kinase II beta. (489 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group). (663 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
MYL12AMyosin regulatory light polypeptide 9. (172 aa)
MYL12BMyosin regulatory light chain 12B. (171 aa)
ABLIM3Actin binding LIM protein family member 3. (680 aa)
CXCL12Stromal cell-derived factor 1 isoform X5; Belongs to the intercrine alpha (chemokine CxC) family. (138 aa)
SMOSmoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family. (782 aa)
EPHA10EPH receptor A10. (1007 aa)
NFATC4Nuclear factor of activated T cells 4. (746 aa)
LIMK1LIM domain kinase 1. (561 aa)
SEMA3Csemaphorin-3C; Belongs to the semaphorin family. (751 aa)
PAK1Serine/threonine-protein kinase PAK 1. (550 aa)
PARD3Partitioning defective 3 homolog isoform X1. (1281 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (593 aa)
PARD6APar-6 family cell polarity regulator alpha. (339 aa)
ROBO1Roundabout homolog 1 isoform X4. (1622 aa)
SRGAP2SLIT-ROBO Rho GTPase-activating protein 2 isoform X1. (172 aa)
SEMA3Dsemaphorin-3D; Belongs to the semaphorin family. (777 aa)
SRGAP3SLIT-ROBO Rho GTPase-activating protein 3 isoform X1. (1099 aa)
PTK2Focal adhesion kinase 1 isoform X3; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1062 aa)
ROBO2Roundabout homolog 2 isoform X2. (1393 aa)
SLIT1LOW QUALITY PROTEIN: slit homolog 1 protein. (1531 aa)
EFNA5ephrin-A5 isoform X1; Belongs to the ephrin family. (228 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (786 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
TRPC1Short transient receptor potential channel 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
EFNB3Ephrin B3. (340 aa)
LIMK2LIM domain kinase 2 isoform X4. (551 aa)
DPYSL5Dihydropyrimidinase-related protein 5. (564 aa)
EPHB1Ephrin type-B receptor 1. (1057 aa)
EPHA1Ephrin type-A receptor 1. (979 aa)
PTCH1Protein patched homolog 1 isoform X1. (1313 aa)
NGEFEphexin-1. (705 aa)
EFNA2Ephrin A2. (165 aa)
EPHB4Ephrin type-B receptor 4. (980 aa)
HRASGTPase HRas isoform X1. (189 aa)
PLXNA3plexin-A3. (1872 aa)
PDK1Protein-serine/threonine kinase. (457 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12 isoform X1. (1542 aa)
PLXNB3plexin-B3. (1891 aa)
SEMA5BSemaphorin 5B. (1138 aa)
NCK1Cytoplasmic protein. (376 aa)
PRKCZProtein kinase C zeta. (592 aa)
PLXNC1plexin-C1. (1547 aa)
CAMK2GCalcium/calmodulin-dependent protein kinase type II subunit gamma isoform X5. (535 aa)
NTNG2Netrin G2. (535 aa)
UNC5ANetrin receptor UNC5A-like. (841 aa)
PLXNB2Plexin B2. (1819 aa)
KRASGTPase KRas. (189 aa)
PLXNA2plexin-A2. (1909 aa)
PPP3CCSerine/threonine-protein phosphatase. (535 aa)
SEMA4Fsemaphorin-4F isoform X1; Belongs to the semaphorin family. (773 aa)
PAK3Serine/threonine-protein kinase PAK 3 isoform X1. (580 aa)
ROCK2Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1378 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
ENSTTRP00000012558annotation not available (443 aa)
ROBO3Roundabout guidance receptor 3. (1386 aa)
EPHB3EPH receptor B3. (994 aa)
NCK2Cytoplasmic protein NCK2 isoform X4. (375 aa)
ABLIM1Actin-binding LIM protein 1 isoform X8. (846 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (449 aa)
RGS3Regulator of G protein signaling 3. (1158 aa)
PAK2Non-specific serine/threonine protein kinase. (523 aa)
PAK5Non-specific serine/threonine protein kinase. (719 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1067 aa)
PARD6BPartitioning defective 6 homolog beta. (372 aa)
FYNTyrosine-protein kinase. (537 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3. (1071 aa)
CAMK2ACalcium/calmodulin-dependent protein kinase type II subunit alpha. (539 aa)
ARSIArylsulfatase I. (571 aa)
ENAHProtein enabled homolog isoform X4. (791 aa)
PAK4P21 (RAC1) activated kinase 4. (591 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
UNC5CNetrin receptor UNC5C isoform X2. (931 aa)
SEMA4Gsemaphorin-4G; Belongs to the semaphorin family. (774 aa)
ABL1Tyrosine-protein kinase. (1148 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1353 aa)
NRASNRAS proto-oncogene, GTPase. (152 aa)
CSDE1Cold shock domain-containing protein E1. (813 aa)
RASA1Ras GTPase-activating protein 1. (1006 aa)
DCCLOW QUALITY PROTEIN: netrin receptor DCC. (1446 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
NEO1Neogenin isoform X4. (1450 aa)
SEMA6Dsemaphorin-6D; Belongs to the semaphorin family. (1073 aa)
TRPC5Short transient receptor potential channel 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
EPHA7Ephrin type-A receptor 7 isoform X1. (998 aa)
SEMA4Bsemaphorin-4B isoform X1; Belongs to the semaphorin family. (827 aa)
EFNA1ephrin-A1 isoform X2; Belongs to the ephrin family. (205 aa)
EFNA3Ephrin A3. (238 aa)
EFNA4Ephrin A4. (166 aa)
ADAM15ADAM metallopeptidase domain 15. (862 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (732 aa)
PTK6Tyrosine-protein kinase. (425 aa)
ENSTTRP00000015396annotation not available (256 aa)
TRPC7Short transient receptor potential channel 7. (861 aa)
SSH2Protein phosphatase Slingshot homolog 2 isoform X1. (1391 aa)
NTN1Netrin-1. (604 aa)
ENSTTRP00000015784annotation not available (149 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X2; Belongs to the protein kinase superfamily. (433 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa)
CFL1Cofilin-2; Belongs to the actin-binding proteins ADF family. (166 aa)
UNC5BNetrin receptor UNC5B-like. (945 aa)
WNT5BWnt family member 5B. (361 aa)
PLXNB1plexin-B1 isoform X1. (2135 aa)
RHOATransforming protein RhoA. (193 aa)
EPHA2Ephrin type-A receptor 2-like. (974 aa)
PLXNA4plexin-A4. (1859 aa)
ENSTTRP00000016529annotation not available (169 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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