STRINGSTRING
CTNNA3 CTNNA3 BMP7 BMP7 FZD6 FZD6 MPP5 MPP5 LLGL2 LLGL2 ENSTTRP00000015043 ENSTTRP00000015043 LOC109547099 LOC109547099 YWHAZ YWHAZ BMP6 BMP6 CDH1 CDH1 PPP2R2B PPP2R2B WWC1 WWC1 PPP2R2C PPP2R2C WNT16 WNT16 MYC MYC WNT7B WNT7B YWHAE YWHAE GSK3B GSK3B TCF7 TCF7 PPP2CA PPP2CA GDF5 GDF5 DVL1 DVL1 WNT5B WNT5B SCRIB SCRIB CCND1 CCND1 PPP2R2A PPP2R2A ENSTTRP00000015677 ENSTTRP00000015677 PPP2CB PPP2CB LOC101332449 LOC101332449 PPP2R1A PPP2R1A NF2 NF2 FZD7 FZD7 LRRC1 LRRC1 SERPINE1 SERPINE1 YWHAQ YWHAQ ITGB2 ITGB2 BIRC2 BIRC2 CTNNA1 CTNNA1 FZD10 FZD10 AJUBA AJUBA APC APC PRKCI PRKCI ACTB ACTB GLI2 GLI2 ENSTTRP00000002090 ENSTTRP00000002090 TCF7L2 TCF7L2 PARD6G PARD6G CTNNA2 CTNNA2 BMP2 BMP2 SMAD2 SMAD2 CCN2 CCN2 BIRC3 BIRC3 SMAD3 SMAD3 DVL3 DVL3 AMOT AMOT TP73 TP73 WWTR1 WWTR1 WNT3 WNT3 WNT9B WNT9B LDAH LDAH WNT8B WNT8B SMAD7 SMAD7 TGFBR2 TGFBR2 WNT10B WNT10B WNT1 WNT1 FGF1 FGF1 SOX2 SOX2 BMPR2 BMPR2 WNT5A WNT5A TEAD2 TEAD2 LOC101324875 LOC101324875 BMP5 BMP5 WNT4 WNT4 ID1 ID1 FZD3 FZD3 LATS1 LATS1 CTNNB1 CTNNB1 FZD4 FZD4 STK3 STK3 ACTG1 ACTG1 AFP AFP RASSF6 RASSF6 TEAD1 TEAD1 MOB1A MOB1A WNT9A WNT9A ENSTTRP00000006381 ENSTTRP00000006381 RASSF1 RASSF1 YWHAB YWHAB TEAD4 TEAD4 DLG5 DLG5 DLG3 DLG3 PPP2R2D PPP2R2D SMAD1 SMAD1 LEF1 LEF1 BMPR1A BMPR1A MYO15A MYO15A LLGL1 LLGL1 PPP1CB PPP1CB MOB1B MOB1B ENSTTRP00000008060 ENSTTRP00000008060 PATJ PATJ ID2 ID2 CRB1 CRB1 PARD3 PARD3 TCF7L1 TCF7L1 AXIN1 AXIN1 PARD6A PARD6A BMP4 BMP4 AXIN2 AXIN2 CCND3 CCND3 TEAD3 TEAD3 CSNK1D CSNK1D WNT8A WNT8A SAV1 SAV1 DLG4 DLG4 DVL2 DVL2 LATS2 LATS2 WNT2B WNT2B WNT6 WNT6 WNT10A WNT10A ENSTTRP00000009655 ENSTTRP00000009655 YWHAH YWHAH WNT2 WNT2 LIMD1 LIMD1 PPP2R1B PPP2R1B BIRC5 BIRC5 WNT7A WNT7A LOC101325454 LOC101325454 CRB2 CRB2 YAP1 YAP1 AREG AREG SMAD4 SMAD4 PRKCZ PRKCZ FZD1 FZD1 FBXW11 FBXW11 GDF6 GDF6 DLG1 DLG1 FRMD6 FRMD6 TGFB1 TGFB1 WTIP WTIP PPP1CA PPP1CA WNT11 WNT11 NKD1 NKD1 TGFB2 TGFB2 TGFBR1 TGFBR1 TP53BP2 TP53BP2 PARD6B PARD6B APC2 APC2 ACTL8 ACTL8 DLG2 DLG2 ENSTTRP00000014050 ENSTTRP00000014050 YWHAG YWHAG BTRC BTRC BMPR1B BMPR1B PPP1CC PPP1CC TGFB3 TGFB3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTNNA3Catenin alpha-3. (895 aa)
BMP7Bone morphogenetic protein 7 isoform X2. (431 aa)
FZD6Frizzled-6 isoform X1; Belongs to the G-protein coupled receptor Fz/Smo family. (707 aa)
MPP5MAGUK p55 subfamily member 5 isoform X1; Belongs to the MAGUK family. (621 aa)
LLGL2Lethal(2) giant larvae protein homolog 2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1068 aa)
ENSTTRP00000015043annotation not available (1532 aa)
LOC109547099Unconventional myosin-XV-like. (488 aa)
YWHAZ14-3-3 protein zeta/delta isoform X1; Belongs to the 14-3-3 family. (245 aa)
BMP6Bone morphogenetic protein 6. (304 aa)
CDH1Cadherin-1 isoform X1; Cadherins are calcium-dependent cell adhesion proteins. (882 aa)
PPP2R2BProtein phosphatase 2 regulatory subunit Bbeta. (509 aa)
WWC1Protein KIBRA. (1118 aa)
PPP2R2CSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (423 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (361 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (453 aa)
WNT7BWnt family member 7B. (350 aa)
YWHAE14-3-3 protein epsilon; Belongs to the 14-3-3 family. (255 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X2; Belongs to the protein kinase superfamily. (433 aa)
TCF7Transcription factor 7. (480 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
GDF5Growth/differentiation factor 5. (489 aa)
DVL1Segment polarity protein dishevelled homolog DVL-1 isoform X1. (700 aa)
WNT5BWnt family member 5B. (361 aa)
SCRIBProtein scribble homolog. (1596 aa)
CCND1G1/S-specific cyclin-D1; Belongs to the cyclin family. (295 aa)
PPP2R2ASerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (505 aa)
ENSTTRP00000015677annotation not available (289 aa)
PPP2CBProtein phosphatase 2 catalytic subunit beta. (285 aa)
LOC101332449Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (318 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like. (589 aa)
NF2Merlin isoform X2. (567 aa)
FZD7Frizzled-7; Belongs to the G-protein coupled receptor Fz/Smo family. (544 aa)
LRRC1Leucine-rich repeat-containing protein 1 isoform X1. (522 aa)
SERPINE1Plasminogen activator inhibitor 1; Belongs to the serpin family. (402 aa)
YWHAQ14-3-3 protein theta; Belongs to the 14-3-3 family. (242 aa)
ITGB2Integrin beta. (750 aa)
BIRC2Baculoviral IAP repeat-containing protein 2. (621 aa)
CTNNA1Catenin alpha-1 isoform X1. (924 aa)
FZD10Frizzled-10; Belongs to the G-protein coupled receptor Fz/Smo family. (581 aa)
AJUBALIM domain-containing protein ajuba. (537 aa)
APCAdenomatous polyposis coli protein isoform X2. (2845 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
ACTBActin beta. (375 aa)
GLI2Zinc finger protein GLI2. (1571 aa)
ENSTTRP00000002090annotation not available (193 aa)
TCF7L2Transcription factor 7-like 2 isoform X5. (639 aa)
PARD6GPartitioning defective 6 homolog gamma. (367 aa)
CTNNA2Catenin alpha-2 isoform X3. (918 aa)
BMP2Bone morphogenetic protein 2. (388 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
CCN2Connective tissue growth factor. (349 aa)
BIRC3Baculoviral IAP repeat-containing protein 3. (601 aa)
SMAD3Mothers against decapentaplegic homolog 3. (291 aa)
DVL3Segment polarity protein dishevelled homolog DVL-3. (498 aa)
AMOTAngiomotin. (998 aa)
TP73Tumor protein p73 isoform X4. (638 aa)
WWTR1WW domain-containing transcription regulator protein 1. (400 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT9BWnt family member 9B. (330 aa)
LDAHLipid droplet-associated hydrolase isoform X1. (315 aa)
WNT8BWnt family member 8B. (353 aa)
SMAD7Mothers against decapentaplegic homolog 7 isoform X1. (426 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (579 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
SOX2Transcription factor SOX-2. (314 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (470 aa)
TEAD2Transcriptional enhancer factor TEF-4 isoform X2. (447 aa)
LOC101324875Casein kinase I. (414 aa)
BMP5Bone morphogenetic protein 5 isoform X2. (454 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
ID1DNA-binding protein inhibitor ID-1. (154 aa)
FZD3Frizzled-3 isoform X2; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
LATS1Serine/threonine-protein kinase LATS1. (958 aa)
CTNNB1Catenin beta-1. (781 aa)
FZD4Frizzled-4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa)
STK3Serine/threonine-protein kinase 3 isoform X1. (480 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
AFPAlpha-fetoprotein. (610 aa)
RASSF6Ras association domain-containing protein 6 isoform X1. (365 aa)
TEAD1Transcriptional enhancer factor TEF-1 isoform X4. (426 aa)
MOB1AMOB kinase activator 1A. (215 aa)
WNT9AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
ENSTTRP00000006381annotation not available (382 aa)
RASSF1Ras association domain-containing protein 1 isoform X1. (342 aa)
YWHAB14-3-3 protein beta/alpha; Belongs to the 14-3-3 family. (246 aa)
TEAD4TEA domain transcription factor 4. (431 aa)
DLG5Disks large homolog 5; Belongs to the MAGUK family. (1816 aa)
DLG3Discs large MAGUK scaffold protein 3. (843 aa)
PPP2R2DSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (420 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
LEF1Lymphoid enhancer binding factor 1. (396 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
MYO15AUnconventional myosin-XV isoform X4. (3486 aa)
LLGL1Lethal(2) giant larvae protein homolog 1-like. (1065 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (367 aa)
MOB1BMOB kinase activator 1B. (265 aa)
ENSTTRP00000008060annotation not available (447 aa)
PATJinaD-like protein isoform X4. (1797 aa)
ID2DNA-binding protein inhibitor ID-2. (134 aa)
CRB1Protein crumbs homolog 1. (1405 aa)
PARD3Partitioning defective 3 homolog isoform X1. (1281 aa)
TCF7L1Transcription factor 7-like 1. (441 aa)
AXIN1Axin-1 isoform X2. (866 aa)
PARD6APar-6 family cell polarity regulator alpha. (339 aa)
BMP4Bone morphogenetic protein 4. (407 aa)
AXIN2Axin-2-like. (839 aa)
CCND3Cyclin D3. (225 aa)
TEAD3Transcriptional enhancer factor TEF-5 isoform X1. (472 aa)
CSNK1DCasein kinase I; Belongs to the protein kinase superfamily. (415 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
SAV1Protein salvador homolog 1. (385 aa)
DLG4Discs large MAGUK scaffold protein 4. (767 aa)
DVL2Segment polarity protein dishevelled homolog DVL-2 isoform X9. (736 aa)
LATS2Large tumor suppressor kinase 2. (992 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (393 aa)
WNT6Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (337 aa)
WNT10AWnt family member 10A. (417 aa)
ENSTTRP00000009655annotation not available (318 aa)
YWHAH14-3-3 protein eta; Belongs to the 14-3-3 family. (246 aa)
WNT2Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (360 aa)
LIMD1LIM domain-containing protein 1 isoform X1. (654 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (664 aa)
BIRC5Baculoviral IAP repeat-containing protein 5. (141 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
LOC101325454Bone morphogenetic protein 8B. (241 aa)
CRB2Crumbs cell polarity complex component 2. (1254 aa)
YAP1Transcriptional coactivator YAP1 isoform X4. (488 aa)
AREGAmphiregulin isoform X2. (253 aa)
SMAD4Mothers against decapentaplegic homolog. (407 aa)
PRKCZProtein kinase C zeta. (592 aa)
FZD1Frizzled-1; Belongs to the G-protein coupled receptor Fz/Smo family. (644 aa)
FBXW11F-box/WD repeat-containing protein 11 isoform X2. (573 aa)
GDF6Growth/differentiation factor 6. (458 aa)
DLG1Disks large homolog 1 isoform X3; Belongs to the MAGUK family. (920 aa)
FRMD6FERM domain-containing protein 6 isoform X1. (589 aa)
TGFB1Transforming growth factor beta 1. (338 aa)
WTIPWilms tumor protein 1-interacting protein. (292 aa)
PPP1CAProtein phosphatase 1 catalytic subunit alpha. (321 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (296 aa)
NKD1Protein naked cuticle homolog 1. (468 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (416 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (458 aa)
TP53BP2Apoptosis-stimulating of p53 protein 2 isoform X1. (1125 aa)
PARD6BPartitioning defective 6 homolog beta. (372 aa)
APC2Adenomatous polyposis coli protein 2-like. (2262 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (364 aa)
DLG2Disks large homolog 2 isoform X2. (966 aa)
ENSTTRP00000014050annotation not available (239 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma. (238 aa)
BTRCF-box/WD repeat-containing protein 1A isoform X1. (605 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (502 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (293 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (411 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (20%) [HD]