STRINGSTRING
PPP1R12A PPP1R12A ITGA2B ITGA2B LOC101315484 LOC101315484 VWF VWF ADCY6 ADCY6 PRKACB PRKACB AKT3 AKT3 ARHGAP35 ARHGAP35 ARHGEF12 ARHGEF12 TLN1 TLN1 PRKCZ PRKCZ RASGRP1 RASGRP1 MAPK12 MAPK12 MAPK11 MAPK11 FGG FGG FGA FGA BTK BTK ROCK2 ROCK2 PLCB4 PLCB4 AKT1 AKT1 ORAI1 ORAI1 MAPK14 MAPK14 MAPK13 MAPK13 ITPR1 ITPR1 FYN FYN ACTL8 ACTL8 PRKACA PRKACA F2RL3 F2RL3 PPP1CC PPP1CC PTRHD1 PTRHD1 ADCY3 ADCY3 TBXAS1 TBXAS1 ROCK1 ROCK1 RDH13 RDH13 RAP1B RAP1B GNAS GNAS PIK3R1 PIK3R1 PTK6 PTK6 ENSTTRP00000015396 ENSTTRP00000015396 PLA2G4A PLA2G4A MAPK1 MAPK1 LYN LYN P2RY12 P2RY12 RHOA RHOA RDH14 RDH14 GNAI3 GNAI3 PRKCI PRKCI ACTB ACTB LCP2 LCP2 LOC101320351 LOC101320351 PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F SNAP23 SNAP23 LOC101336860 LOC101336860 ADCY9 ADCY9 F2 F2 PIK3CD PIK3CD APBB1IP APBB1IP PIK3CG PIK3CG PRKG1 PRKG1 SYK SYK CPN2 CPN2 LRRC15 LRRC15 GP5 GP5 ITPR2 ITPR2 COL1A2 COL1A2 MYLK4 MYLK4 PRKG2 PRKG2 ADCY2 ADCY2 MESDC1 MESDC1 RAP1A RAP1A COL1A1 COL1A1 MAPK3 MAPK3 STIM1 STIM1 SRC SRC TBXA2R TBXA2R ENSTTRP00000005523 ENSTTRP00000005523 P2RX1 P2RX1 ACTG1 ACTG1 GNAI1 GNAI1 PIK3CB PIK3CB PIK3R6 PIK3R6 PIK3R5 PIK3R5 PLCG2 PLCG2 ITPR3 ITPR3 PTGS1 PTGS1 F2R F2R DHRSX DHRSX GNAI2 GNAI2 MYLK2 MYLK2 TLN2 TLN2 ENSTTRP00000007715 ENSTTRP00000007715 PPP1CB PPP1CB ARHGEF1 ARHGEF1 MYL12A MYL12A MYL12B MYL12B VASP VASP ADCY4 ADCY4 GNAQ GNAQ RASGRP2 RASGRP2 VAMP8 VAMP8 FCER1G FCER1G P2RY1 P2RY1 ENSTTRP00000008789 ENSTTRP00000008789 GNA13 GNA13 PLCB1 PLCB1 ITGB1 ITGB1 FGB FGB FERMT3 FERMT3 PLCB3 PLCB3 COL3A1 COL3A1 PIK3R3 PIK3R3 PPP1CA PPP1CA MYLK3 MYLK3 ADCY1 ADCY1 ADCY7 ADCY7 ADCY8 ADCY8 ITGB3 ITGB3 GUCY1A2 GUCY1A2 PLCB2 PLCB2 LOC101332449 LOC101332449 ITGA2 ITGA2 ZNF408 ZNF408 ADCY5 ADCY5 MYLK MYLK GUCY1A1 GUCY1A1 GUCY1B1 GUCY1B1 AKT2 AKT2 NOS3 NOS3 GP1BA GP1BA PIK3CA PIK3CA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PPP1R12AProtein phosphatase 1 regulatory subunit. (1029 aa)
ITGA2BIntegrin alpha-IIb. (1034 aa)
LOC101315484LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like. (613 aa)
VWFVon Willebrand factor. (2796 aa)
ADCY6Adenylate cyclase 6. (1167 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)
ARHGAP35Rho GTPase-activating protein 35 isoform X1. (1510 aa)
ARHGEF12Rho guanine nucleotide exchange factor 12 isoform X1. (1542 aa)
TLN1Talin 1. (2388 aa)
PRKCZProtein kinase C zeta. (592 aa)
RASGRP1RAS guanyl-releasing protein 1 isoform X2. (738 aa)
MAPK12Mitogen-activated protein kinase. (367 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
FGGFibrinogen gamma chain isoform X1. (457 aa)
FGAFibrinogen alpha chain. (820 aa)
BTKTyrosine-protein kinase. (659 aa)
ROCK2Rho-associated protein kinase 2 isoform X1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1378 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
AKT1AKT serine/threonine kinase 1. (480 aa)
ORAI1Calcium release-activated calcium channel protein 1. (238 aa)
MAPK14Mitogen-activated protein kinase 14. (360 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2752 aa)
FYNTyrosine-protein kinase. (537 aa)
ACTL8Actin-like protein 8; Belongs to the actin family. (364 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (351 aa)
F2RL3Proteinase-activated receptor 4; Belongs to the G-protein coupled receptor 1 family. (380 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (293 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (139 aa)
ADCY3Adenylate cyclase type 3. (1141 aa)
TBXAS1thromboxane-A synthase isoform X1; Belongs to the cytochrome P450 family. (534 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1353 aa)
RDH13Retinol dehydrogenase 13 isoform X4; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (334 aa)
RAP1BRas-related protein Rap-1b. (184 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (732 aa)
PTK6Tyrosine-protein kinase. (425 aa)
ENSTTRP00000015396annotation not available (256 aa)
PLA2G4APhospholipase A2. (748 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa)
LYNTyrosine-protein kinase. (491 aa)
P2RY12P2Y purinoceptor 12. (339 aa)
RHOATransforming protein RhoA. (193 aa)
RDH14Retinol dehydrogenase 14 isoform X1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (336 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (597 aa)
ACTBActin beta. (375 aa)
LCP2Lymphocyte cytosolic protein 2 isoform X4. (525 aa)
LOC101320351Cytosolic phospholipase A2 beta isoform X1. (1010 aa)
PLA2G4ECytosolic phospholipase A2 epsilon. (858 aa)
PLA2G4DPhospholipase A2. (817 aa)
PLA2G4FCytosolic phospholipase A2 zeta. (848 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (211 aa)
LOC101336860LOW QUALITY PROTEIN: SCO-spondin. (766 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1226 aa)
F2Coagulation factor II, thrombin. (623 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1049 aa)
APBB1IPAmyloid beta A4 precursor protein-binding family B member 1-interacting protein isoform X1. (659 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform; Belongs to the PI3/PI4-kinase family. (1103 aa)
PRKG1cGMP-dependent protein kinase 1; Belongs to the protein kinase superfamily. (686 aa)
SYKTyrosine-protein kinase. (629 aa)
CPN2Carboxypeptidase N subunit 2. (547 aa)
LRRC15Leucine-rich repeat-containing protein 15. (570 aa)
GP5Platelet glycoprotein V. (560 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2697 aa)
COL1A2Collagen alpha-2(I) chain isoform X1. (1360 aa)
MYLK4Myosin light chain kinase family member 4. (388 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
MESDC1Mesoderm development candidate 1. (362 aa)
RAP1ARas-related protein Rap-1A isoform X1. (184 aa)
COL1A1Collagen type I alpha 1 chain. (1462 aa)
MAPK3Mitogen-activated protein kinase 3. (382 aa)
STIM1Stromal interaction molecule 1 isoform X3. (638 aa)
SRCProto-oncogene tyrosine-protein kinase Src. (538 aa)
TBXA2RThromboxane A2 receptor. (324 aa)
ENSTTRP00000005523annotation not available (722 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
ACTG1Actin, cytoplasmic 2. (375 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
PIK3R6Phosphoinositide 3-kinase regulatory subunit 6. (755 aa)
PIK3R5Phosphoinositide 3-kinase regulatory subunit 5. (836 aa)
PLCG2Phosphoinositide phospholipase C. (1264 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3-like. (2669 aa)
PTGS1Prostaglandin G/H synthase 1. (600 aa)
F2RProteinase-activated receptor 1 isoform X1; Belongs to the G-protein coupled receptor 1 family. (426 aa)
DHRSXDehydrogenase/reductase SDR family member on chromosome X. (293 aa)
GNAI2G protein subunit alpha i2. (351 aa)
MYLK2Myosin light chain kinase 2. (597 aa)
TLN2Talin-2. (2541 aa)
ENSTTRP00000007715annotation not available (128 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (367 aa)
ARHGEF1Rho guanine nucleotide exchange factor 1. (838 aa)
MYL12AMyosin regulatory light polypeptide 9. (172 aa)
MYL12BMyosin regulatory light chain 12B. (171 aa)
VASPVasodilator-stimulated phosphoprotein. (406 aa)
ADCY4Adenylate cyclase type 4; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1077 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
RASGRP2RAS guanyl releasing protein 2. (665 aa)
VAMP8Vesicle-associated membrane protein 8. (100 aa)
FCER1GHigh affinity immunoglobulin epsilon receptor subunit gamma. (66 aa)
P2RY1P2Y purinoceptor 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
ENSTTRP00000008789annotation not available (318 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (282 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (786 aa)
FGBFibrinogen beta chain. (490 aa)
FERMT3Fermitin family member 3. (666 aa)
PLCB3Phosphoinositide phospholipase C. (1230 aa)
COL3A1Collagen alpha-1(III) chain. (1464 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
PPP1CAProtein phosphatase 1 catalytic subunit alpha. (321 aa)
MYLK3Myosin light chain kinase 3. (800 aa)
ADCY1Adenylate cyclase 1. (1088 aa)
ADCY7Adenylate cyclase type 7-like. (1080 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (783 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (749 aa)
PLCB2Phosphoinositide phospholipase C. (1184 aa)
LOC101332449Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (318 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1178 aa)
ZNF408Zinc finger protein 408 isoform X4. (719 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
MYLKMyosin light chain kinase. (1911 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (684 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (610 aa)
AKT2RAC-beta serine/threonine-protein kinase. (481 aa)
NOS3Nitric oxide synthase 3. (1197 aa)
GP1BAPlatelet glycoprotein Ib alpha chain. (556 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1067 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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