STRINGSTRING
IL7R IL7R LOC101338055 LOC101338055 KITLG KITLG ITGA4 ITGA4 CSF3 CSF3 CD3G CD3G LOC101335803 LOC101335803 HLA-DMA HLA-DMA HLA-DOA HLA-DOA ENSTTRP00000004065 ENSTTRP00000004065 CR2 CR2 ITGA5 ITGA5 ENSTTRP00000004328 ENSTTRP00000004328 CD4 CD4 ITGA3 ITGA3 CD37 CD37 FLT3LG FLT3LG CD14 CD14 HLA-DQB2 HLA-DQB2 IL11RA IL11RA IL1R2 IL1R2 IL1R1 IL1R1 ENSTTRP00000006594 ENSTTRP00000006594 CSF2 CSF2 CD34 CD34 MME MME IL5RA IL5RA CD19 CD19 ENSTTRP00000007715 ENSTTRP00000007715 CSF1R CSF1R ENSTTRP00000008070 ENSTTRP00000008070 MS4A1 MS4A1 CD5 CD5 LOC101325973 LOC101325973 ITGA2 ITGA2 DCLK2 DCLK2 IL7 IL7 SIGLEC11 SIGLEC11 GP1BA GP1BA IL2RA IL2RA EPOR EPOR ITGA1 ITGA1 CSF3R CSF3R CD2 CD2 IL11 IL11 CD38 CD38 IL5 IL5 IL4 IL4 FLT3 FLT3 CD7 CD7 CPN2 CPN2 LRRC15 LRRC15 GP5 GP5 LOC101338969 LOC101338969 ENSTTRP00000003726 ENSTTRP00000003726 LOC101321859 LOC101321859 LOC101336776 LOC101336776 HLA-DRA HLA-DRA LOC101328860 LOC101328860 HLA-DOB HLA-DOB CD3E CD3E CD3D CD3D IL6 IL6 CD44 CD44 CD22 CD22 IL4R IL4R CD9 CD9 ITGA2B ITGA2B EPO EPO IL1A IL1A IL1B IL1B ZAN ZAN THPO THPO ITGA6 ITGA6 CSF2RA CSF2RA ITGAM ITGAM TFRC TFRC ITGB3 ITGB3 LOC101335330 LOC101335330 IL6R IL6R TNF TNF LOC101326776 LOC101326776 CD8A CD8A CD8B CD8B KIT KIT ENSTTRP00000014593 ENSTTRP00000014593 ANPEP ANPEP DNTT DNTT ENSTTRP00000015206 ENSTTRP00000015206
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL7RInterleukin-7 receptor subunit alpha. (412 aa)
LOC101338055CD59 glycoprotein isoform X2. (122 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
ITGA4Integrin alpha-4; Belongs to the integrin alpha chain family. (1037 aa)
CSF3Colony stimulating factor 3. (207 aa)
CD3GT-cell surface glycoprotein CD3 gamma chain. (178 aa)
LOC101335803HLA class II histocompatibility antigen, DM beta chain isoform X2. (244 aa)
HLA-DMAHLA class II histocompatibility antigen, DM alpha chain; Belongs to the MHC class II family. (231 aa)
HLA-DOAMajor histocompatibility complex, class II, DO alpha. (250 aa)
ENSTTRP00000004065annotation not available (268 aa)
CR2Complement C3d receptor 2. (1092 aa)
ITGA5Integrin subunit alpha 5. (1053 aa)
ENSTTRP00000004328annotation not available (424 aa)
CD4Tursiops truncatus CD4 molecule (CD4), mRNA. (454 aa)
ITGA3Integrin subunit alpha 3. (1068 aa)
CD37Leukocyte antigen CD37; Belongs to the tetraspanin (TM4SF) family. (281 aa)
FLT3LGFms related tyrosine kinase 3 ligand. (227 aa)
CD14Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa)
HLA-DQB2boLa class II histocompatibility antigen, DQB*0101 beta chain-like isoform X5. (230 aa)
IL11RAInterleukin-11 receptor subunit alpha. (422 aa)
IL1R2Interleukin-1 receptor type 2. (393 aa)
IL1R1Interleukin-1 receptor type 1 isoform X2. (572 aa)
ENSTTRP00000006594annotation not available (143 aa)
CSF2Granulocyte-macrophage colony-stimulating factor. (144 aa)
CD34Hematopoietic progenitor cell antigen CD34 isoform a precursor. (383 aa)
MMENeprilysin. (749 aa)
IL5RAInterleukin-5 receptor subunit alpha isoform X1. (420 aa)
CD19CD19 molecule. (562 aa)
ENSTTRP00000007715annotation not available (128 aa)
CSF1RLOW QUALITY PROTEIN: macrophage colony-stimulating factor 1 receptor-like. (959 aa)
ENSTTRP00000008070annotation not available (119 aa)
MS4A1B-lymphocyte antigen CD20-like. (289 aa)
CD5T-cell surface glycoprotein CD5. (492 aa)
LOC101325973Platelet glycoprotein 4-like isoform X1; Belongs to the CD36 family. (471 aa)
ITGA2Integrin alpha-2; Belongs to the integrin alpha chain family. (1178 aa)
DCLK2Serine/threonine-protein kinase DCLK2 isoform X1. (767 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (176 aa)
SIGLEC11Sialic acid-binding Ig-like lectin 11 isoform X2. (366 aa)
GP1BAPlatelet glycoprotein Ib alpha chain. (556 aa)
IL2RAInterleukin-2 receptor subunit alpha isoform X2. (270 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (509 aa)
ITGA1Integrin alpha-1; Belongs to the integrin alpha chain family. (1178 aa)
CSF3RGranulocyte colony-stimulating factor receptor isoform X3. (853 aa)
CD2T-cell surface antigen CD2. (344 aa)
IL11Interleukin 11. (199 aa)
CD38ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1. (219 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (135 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (134 aa)
FLT3Receptor-type tyrosine-protein kinase FLT3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (980 aa)
CD7T-cell antigen CD7. (206 aa)
CPN2Carboxypeptidase N subunit 2. (547 aa)
LRRC15Leucine-rich repeat-containing protein 15. (570 aa)
GP5Platelet glycoprotein V. (560 aa)
LOC101338969Sialic acid-binding Ig-like lectin 13. (302 aa)
ENSTTRP00000003726annotation not available (363 aa)
LOC101321859IgGFc-binding protein. (5392 aa)
LOC101336776Sialic acid-binding Ig-like lectin 10. (604 aa)
HLA-DRAMajor histocompatibility complex, class II, DR alpha. (252 aa)
LOC101328860SLA class II histocompatibility antigen, DQ haplotype D alpha chain-like isoform X2; Belongs to the MHC class II family. (255 aa)
HLA-DOBHLA class II histocompatibility antigen, DO beta chain isoform X1. (265 aa)
CD3ET-cell surface glycoprotein CD3 epsilon chain. (187 aa)
CD3DT-cell surface glycoprotein CD3 delta chain. (171 aa)
IL6Interleukin-6. (208 aa)
CD44CD44 antigen isoform X1. (742 aa)
CD22B-cell receptor CD22. (844 aa)
IL4RInterleukin-4 receptor subunit alpha isoform X1. (805 aa)
CD9Tetraspanin. (205 aa)
ITGA2BIntegrin alpha-IIb. (1034 aa)
EPOErythropoietin. (192 aa)
IL1AInterleukin-1; Belongs to the IL-1 family. (264 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (265 aa)
ZANZonadhesin. (2637 aa)
THPOThrombopoietin. (353 aa)
ITGA6Integrin alpha-6 isoform X1; Belongs to the integrin alpha chain family. (1130 aa)
CSF2RAGranulocyte-macrophage colony-stimulating factor receptor subunit alpha isoform X1. (305 aa)
ITGAMIntegrin alpha-M-like. (1139 aa)
TFRCTransferrin receptor protein 1 isoform X1. (770 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (783 aa)
LOC101335330Sialic acid-binding Ig-like lectin 5. (553 aa)
IL6RInterleukin-6 receptor subunit alpha isoform X2. (466 aa)
TNFTumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (233 aa)
LOC101326776Platelet glycoprotein 4; Belongs to the CD36 family. (472 aa)
CD8AT-cell surface glycoprotein CD8 alpha chain isoform X1. (236 aa)
CD8BT-cell surface glycoprotein CD8 beta chain. (206 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (953 aa)
ENSTTRP00000014593annotation not available (370 aa)
ANPEPAminopeptidase N. (964 aa)
DNTTDNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (510 aa)
ENSTTRP00000015206annotation not available (554 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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