STRINGSTRING
KRAS KRAS PPP3CC PPP3CC BTK BTK PIK3R3 PIK3R3 CD81 CD81 PIK3CA PIK3CA AKT1 AKT1 SOS1 SOS1 GRB2 GRB2 NFATC3 NFATC3 DAPP1 DAPP1 NRAS NRAS CSDE1 CSDE1 VAV2 VAV2 PIK3AP1 PIK3AP1 PIK3R1 PIK3R1 INPP5D INPP5D RASGRP3 RASGRP3 NFATC1 NFATC1 ENSTTRP00000015784 ENSTTRP00000015784 GSK3B GSK3B MAPK1 MAPK1 LYN LYN ENSTTRP00000016529 ENSTTRP00000016529 AKT2 AKT2 PPP3CB PPP3CB RAC2 RAC2 ENSTTRP00000001195 ENSTTRP00000001195 LOC101333314 LOC101333314 ENSTTRP00000001198 ENSTTRP00000001198 BCL10 BCL10 RAC3 RAC3 CARD11 CARD11 IKBKB IKBKB RELA RELA PRKCB PRKCB PPP3CA PPP3CA PIK3CD PIK3CD SYK SYK SOS2 SOS2 CR2 CR2 ERAS ERAS PTPN6 PTPN6 RAC1 RAC1 BLNK BLNK MAPK3 MAPK3 ENSTTRP00000005523 ENSTTRP00000005523 VAV1 VAV1 CD72 CD72 PIK3CB PIK3CB ENSTTRP00000006219 ENSTTRP00000006219 ENSTTRP00000006413 ENSTTRP00000006413 PLCG2 PLCG2 NFKBIE NFKBIE CD79B CD79B IKBKG IKBKG MALT1 MALT1 NFATC2 NFATC2 FOS FOS CD19 CD19 NFKBIA NFKBIA CD79A CD79A CD22 CD22 VAV3 VAV3 INPPL1 INPPL1 MAP2K1 MAP2K1 NFKB1 NFKB1 HRAS HRAS AKT3 AKT3 JUN JUN NFKBIB NFKBIB CHUK CHUK
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KRASGTPase KRas. (189 aa)
PPP3CCSerine/threonine-protein phosphatase. (535 aa)
BTKTyrosine-protein kinase. (659 aa)
PIK3R3Phosphatidylinositol 3-kinase regulatory subunit gamma. (461 aa)
CD81CD81 molecule. (214 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; Belongs to the PI3/PI4-kinase family. (1067 aa)
AKT1AKT serine/threonine kinase 1. (480 aa)
SOS1Son of sevenless homolog 1 isoform X1. (1304 aa)
GRB2Growth factor receptor-bound protein 2. (156 aa)
NFATC3Nuclear factor of activated T-cells, cytoplasmic 3. (1071 aa)
DAPP1Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide isoform X1. (280 aa)
NRASNRAS proto-oncogene, GTPase. (152 aa)
CSDE1Cold shock domain-containing protein E1. (813 aa)
VAV2Vav guanine nucleotide exchange factor 2. (872 aa)
PIK3AP1Phosphoinositide 3-kinase adapter protein 1 isoform X1. (800 aa)
PIK3R1Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1. (732 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1128 aa)
RASGRP3Ras guanyl-releasing protein 3. (692 aa)
NFATC1Nuclear factor of activated T-cells, cytoplasmic 1. (904 aa)
ENSTTRP00000015784annotation not available (149 aa)
GSK3BGlycogen synthase kinase-3 beta isoform X2; Belongs to the protein kinase superfamily. (433 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa)
LYNTyrosine-protein kinase. (491 aa)
ENSTTRP00000016529annotation not available (169 aa)
AKT2RAC-beta serine/threonine-protein kinase. (481 aa)
PPP3CBSerine/threonine-protein phosphatase. (525 aa)
RAC2Ras-related C3 botulinum toxin substrate 1. (192 aa)
ENSTTRP00000001195annotation not available (464 aa)
LOC101333314Leukocyte immunoglobulin-like receptor subfamily A member 4. (586 aa)
ENSTTRP00000001198annotation not available (387 aa)
BCL10B-cell lymphoma/leukemia 10. (233 aa)
RAC3Ras-related C3 botulinum toxin substrate 1 isoform X2. (192 aa)
CARD11Caspase recruitment domain-containing protein 11. (1165 aa)
IKBKBInhibitor of nuclear factor kappa-B kinase subunit beta. (735 aa)
RELARELA proto-oncogene, NF-kB subunit. (574 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
PPP3CASerine/threonine-protein phosphatase. (560 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; Belongs to the PI3/PI4-kinase family. (1049 aa)
SYKTyrosine-protein kinase. (629 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1303 aa)
CR2Complement C3d receptor 2. (1092 aa)
ERASES cell expressed Ras. (233 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type 6. (620 aa)
RAC1Ras-related C3 botulinum toxin substrate 1 isoform X1. (199 aa)
BLNKLOW QUALITY PROTEIN: B-cell linker protein. (459 aa)
MAPK3Mitogen-activated protein kinase 3. (382 aa)
ENSTTRP00000005523annotation not available (722 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
CD72B-cell differentiation antigen CD72. (360 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1065 aa)
ENSTTRP00000006219annotation not available (645 aa)
ENSTTRP00000006413annotation not available (364 aa)
PLCG2Phosphoinositide phospholipase C. (1264 aa)
NFKBIENF-kappa-B inhibitor epsilon isoform X1. (482 aa)
CD79BB-cell antigen receptor complex-associated protein beta chain. (230 aa)
IKBKGNF-kappa-B essential modulator. (424 aa)
MALT1Mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X1. (758 aa)
NFATC2Nuclear factor of activated T-cells, cytoplasmic 2 isoform X2. (919 aa)
FOSProto-oncogene c-Fos. (374 aa)
CD19CD19 molecule. (562 aa)
NFKBIANF-kappa-B inhibitor alpha. (314 aa)
CD79ACD79a molecule. (223 aa)
CD22B-cell receptor CD22. (844 aa)
VAV3Guanine nucleotide exchange factor VAV3. (846 aa)
INPPL1Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2-like. (1262 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (393 aa)
NFKB1Nuclear factor NF-kappa-B p105 subunit isoform X1. (964 aa)
HRASGTPase HRas isoform X1. (189 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (462 aa)
JUNTranscription factor AP-1; Belongs to the bZIP family. (321 aa)
NFKBIBNF-kappa-B inhibitor beta. (359 aa)
CHUKInhibitor of nuclear factor kappa-B kinase subunit alpha isoform X1. (744 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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