STRINGSTRING
HTR2C HTR2C ENSTTRP00000000542 ENSTTRP00000000542 ADCY5 ADCY5 ENSTTRP00000000575 ENSTTRP00000000575 GNG5 GNG5 HTR4 HTR4 HTR1A HTR1A GNAI3 GNAI3 GNB4 GNB4 KCNJ9 KCNJ9 GNG3 GNG3 BRAF BRAF LOC101320351 LOC101320351 PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F HTR2A HTR2A PRKCB PRKCB HTR1F HTR1F CACNA1C CACNA1C APP APP GNG8 GNG8 ENSTTRP00000003029 ENSTTRP00000003029 ITPR2 ITPR2 KCNJ3 KCNJ3 HTR1E HTR1E HTR6 HTR6 GNGT2 GNGT2 GNB5 GNB5 CYP2J2 CYP2J2 GNB3 GNB3 ERAS ERAS ENSTTRP00000004849 ENSTTRP00000004849 SLC18A2 SLC18A2 ENSTTRP00000005002 ENSTTRP00000005002 KCNJ6 KCNJ6 MAPK3 MAPK3 GNG2 GNG2 GNB2 GNB2 GABRB1 GABRB1 GNAI1 GNAI1 ENSTTRP00000006141 ENSTTRP00000006141 TPH2 TPH2 ITPR3 ITPR3 GNG7 GNG7 PTGS1 PTGS1 PELP1 PELP1 GNAI2 GNAI2 GNG4 GNG4 PRKCA PRKCA ALOX12 ALOX12 GNAQ GNAQ DDC DDC MAOA MAOA MAOB MAOB KCNJ5 KCNJ5 PLCB1 PLCB1 ARAF ARAF TRPC1 TRPC1 HTR5A HTR5A MAP2K1 MAP2K1 GNG13 GNG13 PLCB3 PLCB3 ALOX15B ALOX15B KCNN2 KCNN2 DUSP1 DUSP1 GABRB3 GABRB3 PRKCG PRKCG HRAS HRAS PRKACB PRKACB CYP2W1 CYP2W1 ALOX5 ALOX5 CACNA1A CACNA1A HTR3B HTR3B HTR3A HTR3A PTGS2 PTGS2 CACNA1D CACNA1D RAPGEF3 RAPGEF3 KRAS KRAS GNAO1 GNAO1 SLC18A1 SLC18A1 CACNA1S CACNA1S CACNA1B CACNA1B TPH1 TPH1 PLCB4 PLCB4 ITPR1 ITPR1 PRKACA PRKACA HTR7 HTR7 PLCB2 PLCB2 GNG12 GNG12 NRAS NRAS CSDE1 CSDE1 GNAS GNAS HTR2B HTR2B GNGT1 GNGT1 GNG11 GNG11 ENSTTRP00000015348 ENSTTRP00000015348 GABRB2 GABRB2 KCND2 KCND2 SLC6A4 SLC6A4 PLA2G4A PLA2G4A ENSTTRP00000015784 ENSTTRP00000015784 MAPK1 MAPK1 CACNA1F CACNA1F
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HTR2C5-hydroxytryptamine receptor 2C. (457 aa)
ENSTTRP00000000542annotation not available (353 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
ENSTTRP00000000575annotation not available (325 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
HTR45-hydroxytryptamine receptor 4 isoform X4; Belongs to the G-protein coupled receptor 1 family. (427 aa)
HTR1A5-hydroxytryptamine receptor 1A. (422 aa)
GNAI3G protein subunit alpha i3. (354 aa)
GNB4Guanine nucleotide-binding protein subunit beta-4. (340 aa)
KCNJ9Potassium inwardly rectifying channel subfamily J member 9. (283 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X4. (757 aa)
LOC101320351Cytosolic phospholipase A2 beta isoform X1. (1010 aa)
PLA2G4ECytosolic phospholipase A2 epsilon. (858 aa)
PLA2G4DPhospholipase A2. (817 aa)
PLA2G4FCytosolic phospholipase A2 zeta. (848 aa)
HTR2A5-hydroxytryptamine receptor 2A. (470 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
HTR1F5-hydroxytryptamine receptor 1F. (365 aa)
CACNA1CVoltage-dependent L-type calcium channel subunit alpha-1C-like. (2195 aa)
APPAmyloid beta A4 protein isoform X1. (763 aa)
GNG8G protein subunit gamma 8. (70 aa)
ENSTTRP00000003029annotation not available (275 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2697 aa)
KCNJ3G protein-activated inward rectifier potassium channel 1 isoform X1. (501 aa)
HTR1E5-hydroxytryptamine receptor 1E. (365 aa)
HTR65-hydroxytryptamine receptor 6. (440 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GNB5Guanine nucleotide-binding protein subunit beta-5. (395 aa)
CYP2J2Cytochrome P450 2J2 isoform X1; Belongs to the cytochrome P450 family. (461 aa)
GNB3G protein subunit beta 3. (340 aa)
ERASES cell expressed Ras. (233 aa)
ENSTTRP00000004849annotation not available (371 aa)
SLC18A2Synaptic vesicular amine transporter. (515 aa)
ENSTTRP00000005002annotation not available (435 aa)
KCNJ6G protein-activated inward rectifier potassium channel 2. (414 aa)
MAPK3Mitogen-activated protein kinase 3. (382 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
GNB2G protein subunit beta 2. (340 aa)
GABRB1LOW QUALITY PROTEIN: gamma-aminobutyric acid receptor subunit beta-1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
ENSTTRP00000006141annotation not available (161 aa)
TPH2Tryptophan 5-hydroxylase 2. (497 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3-like. (2669 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PTGS1Prostaglandin G/H synthase 1. (600 aa)
PELP1Proline-, glutamic acid- and leucine-rich protein 1 isoform X2. (1249 aa)
GNAI2G protein subunit alpha i2. (351 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S-type isoform X1. (663 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
DDCaromatic-L-amino-acid decarboxylase isoform X1. (480 aa)
MAOAAmine oxidase. (359 aa)
MAOBAmine oxidase. (555 aa)
KCNJ5G protein-activated inward rectifier potassium channel 4 isoform X1. (419 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform X1. (609 aa)
TRPC1Short transient receptor potential channel 1 isoform X1; Belongs to the transient receptor (TC 1.A.4) family. (794 aa)
HTR5A5-hydroxytryptamine receptor 5A. (357 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (393 aa)
GNG13Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13. (67 aa)
PLCB3Phosphoinositide phospholipase C. (1230 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (675 aa)
KCNN2Small conductance calcium-activated potassium channel protein 2 isoform X1. (758 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (366 aa)
GABRB3Gamma-aminobutyric acid receptor subunit beta-3 isoform X2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (519 aa)
PRKCGProtein kinase C gamma type. (697 aa)
HRASGTPase HRas isoform X1. (189 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
CYP2W1LOW QUALITY PROTEIN: cytochrome P450 2W1; Belongs to the cytochrome P450 family. (483 aa)
ALOX5Arachidonate 5-lipoxygenase isoform X1. (672 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2393 aa)
HTR3B5-hydroxytryptamine receptor 3B; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (442 aa)
HTR3A5-hydroxytryptamine receptor 3A isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (517 aa)
PTGS2Prostaglandin G/H synthase 2. (603 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2182 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3 isoform X2. (923 aa)
KRASGTPase KRas. (189 aa)
GNAO1G protein subunit alpha o1. (354 aa)
SLC18A1Chromaffin granule amine transporter isoform X1. (517 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha-1S-like. (1856 aa)
CACNA1BCalcium voltage-gated channel subunit alpha1 B. (2178 aa)
TPH1Tryptophan 5-hydroxylase 1. (465 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2752 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (351 aa)
HTR75-hydroxytryptamine receptor 7 isoform X2; Belongs to the G-protein coupled receptor 1 family. (306 aa)
PLCB2Phosphoinositide phospholipase C. (1184 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (53 aa)
NRASNRAS proto-oncogene, GTPase. (152 aa)
CSDE1Cold shock domain-containing protein E1. (813 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
HTR2BLOW QUALITY PROTEIN: 5-hydroxytryptamine receptor 2B. (479 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
ENSTTRP00000015348annotation not available (321 aa)
GABRB2Gamma-aminobutyric acid receptor subunit beta-2 isoform X1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
KCND2Potassium voltage-gated channel subfamily D member 2 isoform X2; Belongs to the potassium channel family. (630 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (665 aa)
PLA2G4APhospholipase A2. (748 aa)
ENSTTRP00000015784annotation not available (149 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa)
CACNA1FVoltage-dependent L-type calcium channel subunit alpha-1F isoform X1. (1973 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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