STRINGSTRING
PLCB2 PLCB2 PPP2CB PPP2CB PPP1R17 PPP1R17 PPP2R1A PPP2R1A GUCY1A1 GUCY1A1 GUCY1B1 GUCY1B1 GNAI3 GNAI3 FBXO21 FBXO21 NOS1 NOS1 BRAF BRAF LOC101320351 LOC101320351 PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F PRKCB PRKCB GRIA3 GRIA3 PRKG1 PRKG1 ITPR2 ITPR2 GNA12 GNA12 PRKG2 PRKG2 CRH CRH ERAS ERAS MAPK3 MAPK3 GRIA1 GRIA1 GNAI1 GNAI1 ENSTTRP00000006413 ENSTTRP00000006413 ITPR3 ITPR3 GRID2 GRID2 GNAI2 GNAI2 PRKCA PRKCA GNAQ GNAQ GNAZ GNAZ ENSTTRP00000008594 ENSTTRP00000008594 GNA13 GNA13 PLCB1 PLCB1 GRM1 GRM1 ARAF ARAF MAP2K1 MAP2K1 PLCB3 PLCB3 PPP2R1B PPP2R1B RYR1 RYR1 LOC101315484 LOC101315484 PRKCG PRKCG HRAS HRAS GRIA2 GRIA2 CACNA1A CACNA1A GNA11 GNA11 KRAS KRAS GNAO1 GNAO1 GUCY1A2 GUCY1A2 PLCB4 PLCB4 ITPR1 ITPR1 IGF1R IGF1R NRAS NRAS CSDE1 CSDE1 GNAS GNAS PLA2G4A PLA2G4A ENSTTRP00000015784 ENSTTRP00000015784 MAPK1 MAPK1 LYN LYN PPP2CA PPP2CA IGF1 IGF1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLCB2Phosphoinositide phospholipase C. (1184 aa)
PPP2CBProtein phosphatase 2 catalytic subunit beta. (285 aa)
PPP1R17Protein phosphatase 1 regulatory subunit 17. (154 aa)
PPP2R1ASerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like. (589 aa)
GUCY1A1Guanylate cyclase soluble subunit alpha-3; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (684 aa)
GUCY1B1Guanylate cyclase soluble subunit beta-1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (610 aa)
GNAI3G protein subunit alpha i3. (354 aa)
FBXO21F-box only protein 21 isoform X1. (627 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1466 aa)
BRAFSerine/threonine-protein kinase B-raf isoform X4. (757 aa)
LOC101320351Cytosolic phospholipase A2 beta isoform X1. (1010 aa)
PLA2G4ECytosolic phospholipase A2 epsilon. (858 aa)
PLA2G4DPhospholipase A2. (817 aa)
PLA2G4FCytosolic phospholipase A2 zeta. (848 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
GRIA3Glutamate receptor 3 isoform X2. (894 aa)
PRKG1cGMP-dependent protein kinase 1; Belongs to the protein kinase superfamily. (686 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2697 aa)
GNA12Guanine nucleotide-binding protein subunit alpha-12. (382 aa)
PRKG2cGMP-dependent protein kinase. (762 aa)
CRHCorticoliberin. (193 aa)
ERASES cell expressed Ras. (233 aa)
MAPK3Mitogen-activated protein kinase 3. (382 aa)
GRIA1Glutamate receptor 1 isoform X1. (905 aa)
GNAI1Guanine nucleotide-binding protein G(I) subunit alpha-1. (354 aa)
ENSTTRP00000006413annotation not available (364 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3-like. (2669 aa)
GRID2Glutamate receptor ionotropic, delta-2. (1008 aa)
GNAI2G protein subunit alpha i2. (351 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
GNAZGuanine nucleotide-binding protein G(Z) subunit alpha. (355 aa)
ENSTTRP00000008594annotation not available (430 aa)
GNA13Guanine nucleotide-binding protein subunit alpha-13 isoform X1. (282 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
GRM1Metabotropic glutamate receptor 1 isoform X1. (1195 aa)
ARAFSerine/threonine-protein kinase A-Raf isoform X1. (609 aa)
MAP2K1Dual specificity mitogen-activated protein kinase kinase 1. (393 aa)
PLCB3Phosphoinositide phospholipase C. (1230 aa)
PPP2R1BSerine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform. (664 aa)
RYR1Ryanodine receptor 1. (5021 aa)
LOC101315484LOW QUALITY PROTEIN: guanylate cyclase soluble subunit beta-2-like. (613 aa)
PRKCGProtein kinase C gamma type. (697 aa)
HRASGTPase HRas isoform X1. (189 aa)
GRIA2Glutamate receptor 2 isoform X4. (883 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (2393 aa)
GNA11G protein subunit alpha 11. (359 aa)
KRASGTPase KRas. (189 aa)
GNAO1G protein subunit alpha o1. (354 aa)
GUCY1A2Guanylate cyclase soluble subunit alpha-2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (749 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2752 aa)
IGF1RTyrosine-protein kinase receptor. (1358 aa)
NRASNRAS proto-oncogene, GTPase. (152 aa)
CSDE1Cold shock domain-containing protein E1. (813 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
PLA2G4APhospholipase A2. (748 aa)
ENSTTRP00000015784annotation not available (149 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (320 aa)
LYNTyrosine-protein kinase. (491 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
IGF1Insulin-like growth factor 1 transcript variant X4. (194 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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