STRINGSTRING
TTF2 TTF2 HSPA5 HSPA5 GPX1 GPX1 GSR GSR CREB3L1 CREB3L1 GPX7 GPX7 GNAS GNAS CREB1 CREB1 PDIA4 PDIA4 LOC101330299 LOC101330299 LOC101329723 LOC101329723 CREB5 CREB5 ADCY3 ADCY3 PTRHD1 PTRHD1 PRKACA PRKACA TPO TPO ATF4 ATF4 ITPR1 ITPR1 TTF1 TTF1 PLCB4 PLCB4 ENSTTRP00000012876 ENSTTRP00000012876 DUOXA2 DUOXA2 DUOX2 DUOX2 ADCY8 ADCY8 ATP1B3 ATP1B3 PAX8 PAX8 CREB3 CREB3 CGA CGA SERPINA7 SERPINA7 ATP1A1 ATP1A1 PRKACB PRKACB ADCY6 ADCY6 CREB3L4 CREB3L4 PRKCG PRKCG PLCB3 PLCB3 ATP1B2 ATP1B2 CREB3L3 CREB3L3 TSHB TSHB SYCP1 SYCP1 PLCB1 PLCB1 ASGR1 ASGR1 ASGR2 ASGR2 HSP90B1 HSP90B1 SLC5A5 SLC5A5 GNAQ GNAQ GPX8 GPX8 ADCY4 ADCY4 ENSTTRP00000007871 ENSTTRP00000007871 PRKCA PRKCA LOC101329840 LOC101329840 ITPR3 ITPR3 CLEC10A CLEC10A SLC26A4 SLC26A4 ALB ALB IYD IYD LRP2 LRP2 ATF6B ATF6B GPX3 GPX3 ATP1B1 ATP1B1 CREB3L2 CREB3L2 ADCY2 ADCY2 ITPR2 ITPR2 ENSTTRP00000002833 ENSTTRP00000002833 ATP1B4 ATP1B4 ADCY9 ADCY9 PRKCB PRKCB TTR TTR ATP1A4 ATP1A4 ATP1A2 ATP1A2 GPX2 GPX2 TSHR TSHR ADCY5 ADCY5 CANX CANX ATF2 ATF2 PLCB2 PLCB2 ADCY7 ADCY7 ADCY1 ADCY1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TTF2Transcription termination factor 2. (1165 aa)
HSPA578 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family. (654 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (206 aa)
GSRGlutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (518 aa)
CREB3L1Cyclic AMP-responsive element-binding protein 3-like protein 1. (519 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (186 aa)
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoforms XLas. (969 aa)
CREB1Cyclic AMP-responsive element-binding protein 1 isoform X1. (341 aa)
PDIA4Protein disulfide-isomerase A4-like; Belongs to the protein disulfide isomerase family. (645 aa)
LOC101330299Glutathione peroxidase; Belongs to the glutathione peroxidase family. (191 aa)
LOC101329723Glutathione peroxidase 6. (119 aa)
CREB5Cyclic AMP-responsive element-binding protein 5 isoform X1. (508 aa)
ADCY3Adenylate cyclase type 3. (1141 aa)
PTRHD1Putative peptidyl-tRNA hydrolase PTRHD1. (139 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (351 aa)
TPOThyroid peroxidase isoform X1. (881 aa)
ATF4Cyclic AMP-dependent transcription factor ATF-4. (351 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2752 aa)
TTF1Transcription termination factor 1 isoform X2. (762 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1192 aa)
ENSTTRP00000012876annotation not available (865 aa)
DUOXA2Dual oxidase maturation factor 2. (321 aa)
DUOX2Dual oxidase 2. (1544 aa)
ADCY8Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1250 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (277 aa)
PAX8Paired box protein Pax-8. (445 aa)
CREB3Cyclic AMP-responsive element-binding protein 3. (365 aa)
CGAGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (118 aa)
SERPINA7Thyroxine-binding globulin; Belongs to the serpin family. (412 aa)
ATP1A1Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
PRKACBcAMP-dependent protein kinase catalytic subunit beta isoform X1; Belongs to the protein kinase superfamily. (397 aa)
ADCY6Adenylate cyclase 6. (1167 aa)
CREB3L4Cyclic AMP-responsive element-binding protein 3-like protein 4 isoform X3. (395 aa)
PRKCGProtein kinase C gamma type. (697 aa)
PLCB3Phosphoinositide phospholipase C. (1230 aa)
ATP1B2ATPase Na+/K+ transporting subunit beta 2. (290 aa)
CREB3L3Cyclic AMP-responsive element-binding protein 3-like protein 3. (455 aa)
TSHBThyroid stimulating hormone beta subunit. (140 aa)
SYCP1Synaptonemal complex protein 1. (945 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1183 aa)
ASGR1Asialoglycoprotein receptor 1. (291 aa)
ASGR2Asialoglycoprotein receptor 2. (308 aa)
HSP90B1Endoplasmin. (803 aa)
SLC5A5Solute carrier family 5 member 5. (639 aa)
GNAQGuanine nucleotide-binding protein G(Q) subunit alpha isoform X1. (329 aa)
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (209 aa)
ADCY4Adenylate cyclase type 4; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1077 aa)
ENSTTRP00000007871annotation not available (1012 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
LOC101329840LOW QUALITY PROTEIN: serpin A9; Belongs to the serpin family. (426 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3-like. (2669 aa)
CLEC10AC-type lectin domain family 10 member A-like. (291 aa)
SLC26A4Pendrin; Sodium-independent transporter of chloride and iodide. Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. (776 aa)
ALBSerum albumin isoform X1. (623 aa)
IYDIodotyrosine deiodinase 1. (289 aa)
LRP2Low-density lipoprotein receptor-related protein 2. (4599 aa)
ATF6BActivating transcription factor 6 beta. (671 aa)
GPX3Glutathione peroxidase 3. (225 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (284 aa)
CREB3L2LOW QUALITY PROTEIN: cyclic AMP-responsive element-binding protein 3-like protein 2. (520 aa)
ADCY2Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1082 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2697 aa)
ENSTTRP00000002833annotation not available (131 aa)
ATP1B4Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (353 aa)
ADCY9Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1226 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (673 aa)
TTRTransthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (145 aa)
ATP1A4Sodium/potassium-transporting ATPase subunit alpha. (1009 aa)
ATP1A2ATPase Na+/K+ transporting subunit alpha 2. (1020 aa)
GPX2Glutathione peroxidase 2. (185 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
ADCY5Adenylate cyclase 5. (1263 aa)
CANXCalnexin isoform X1. (573 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2 isoform X1. (505 aa)
PLCB2Phosphoinositide phospholipase C. (1184 aa)
ADCY7Adenylate cyclase type 7-like. (1080 aa)
ADCY1Adenylate cyclase 1. (1088 aa)
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.